run_metadata: 53815
This data as json
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 53815 | SRR10058763 | SRX6792672 | SRS5347942 | SRP220275 | PRJNA563535 | Dopamine Agonists Have Differential Effects on Molecular Targets and Behavior | PRJNA563535 | Other | Dopamine is critical for neural circuit modulation and also affects behavior. Dopamine agonists have been used to treat multiple neurological disorders and lead to different clinical outcomes. However their effects on behavior and the underlying molecular mechanisms are unclear. In this study we used zebrafish as a model to study the effects of the dopamine agonists SKF 38393 quinpirole and pergolide on behavior and systematically analyzed their effects on molecular events with highresolution transcriptome analysis. | Pergo1 | strain:not collected|age:7 days|sex:pooled male and female|tissue:whole mount|treatment:Pergo1|BioSampleModel:Model organism or animal | Dopamine Agonists Have Differential Effects on Molecular Targets and Behavior | Pergo1 | Pergo1 | Pergo1 | RNA-Seq | TRANSCRIPTOMIC | PCR | PAIRED | ILLUMINA | Illumina HiSeq 4000 | SRP220275 | Pergo1_1.fq.gz Pergo1_2.fq.gz | fastq fastq | 9002685900.0 | 30008953.0 | Pergo1 1.fq.gz | 0:150 1:150 | A:2284233380;C:2226407977;G:2221649755;T:2270297656;N:97132 | 150 | 150 | 2284233380 | 2226407977 | 2221649755 | 2270297656 | 97132 | SRX6792672 | SRS5347942 | SRA954969 | Nantong University|Key Laboratory of Neuroregeneration of Jiangsu and | Nantong University | 2 | 0.96714 | 0.96683 | 0.06127 | 0.06067 | 0.65234 | 0.65228 | 0.48061 | 0.48752 | 150 | 150 | B | B | biological fallback assumption | illumina | hiseq_era | unknown | random_priming | unknown | bulk | unknown | unknown | China | 2019-09-03 | Larval | Larval | Whole Organism | All anatomical structures |