run_metadata: 25319
This data as json
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 25319 | SRR25786852 | SRX21509235 | SRS18740265 | SRP457465 | PRJNA1010662 | The miR 144/Hmgn2 regulatory axis orchestrates chromatin organization during erythropoiesis. | PRJNA1010662 | Other | Differentiation of stem and progenitor cells is a highly regulated process that involves the coordinated action of multiple layers of regulation. Here we show how the post transcriptional regulatory layer instructs the chromatin regulation level via miR 144 and its targets to orchestrate chromatin condensation during erythropoiesis. The loss of miR 144 leads to impaired chromatin condensation during erythrocyte maturation. | RNA seq Erythrocytes Wild type Danio rerio 3 dpf | CD KD WT | strain:Wildtype|age:3 days|collection date:not provided|geo loc name:not provided|sex:mixed|tissue:whole embryo|BioSampleModel:Model organism or animal | RNA seq Erythrocytes Wild type Danio rerio 3 dpf replicate 1 | CD KD WT1 | CD KD WT1 | Libraries were made using Illumina mRNA seq library prep kit | RNA-Seq | TRANSCRIPTOMIC | Oligo-dT | PAIRED | ILLUMINA | NextSeq 2000 | SRP457465 | CD_KD_WT1-R_S1_L001_R1_001.fastq.gz CD_KD_WT1-R_S1_L001_R2_001.fastq.gz | fastq fastq | 13279321095.0 | 67105432.0 | CD KD WT1 R S1 L001 R1 001.fastq.gz | 0:98.98 1:98.91 | A:3310018513;C:3313506420;G:3374819099;T:3243710775;N:37266288 | 98 | 98 | 3310018513 | 3313506420 | 3374819099 | 3243710775 | 37266288 | SRX21509235 | SRS18740265 | SRA1701488 | University of East Anglia|Biological Sciences | University of East Anglia | 2 | 0.97038 | 0.97604 | 0.04235 | 0.04238 | 0.83676 | 0.8367 | 0.45607 | 0.45443 | 101 | 101 | B | B | biological fallback assumption | illumina | nextseq_v2 | unknown | poly_a | unknown | bulk | unknown | unknown | United Kingdom | 2023-08-30 | Larval | Larval | Whole Organism | All anatomical structures |