rowid,run.accession,experiment.accession,sample.accession,study.accession,bioproject,study.title,study.alias,study.type,study.abstract,study.attributes,study.PMIDs,sample.description,sample.title,sample.alias,sample.centername,sample.attributes,GEOsample.title,GEOsample.dataprocessing,GEOsample.source,GEOsample.treatmentprotocol,GEOsample.extractprotocol,GEOsample.growthprotocol,GEOsample.characteristics,GEOsample.accession,experiment.title,experiment.alias,experiment.library_name,experiment.design_description,experiment.library_construction_protocol,experiment.attributes,experiment.library_strategy,experiment.library_source,experiment.library_selection,experiment.library_layout,experiment.platform,experiment.instrument_model,experiment.spot_descriptor,experiment.study_ref,run.title,run.attributes,run.filename,run.semantic_name,run.total_bases,run.total_spots,run.alias,run.read_lengths,run.base_counts,run.r1_length,run.r2_length,run.r3_length,run.r4_length,run.Acount,run.Ccount,run.Gcount,run.Tcount,run.Ncount,run.experiment,run.pool_member,submission.accession,submission.srasource,submission.bioprojectsource,seqdetective.n_mates,seqdetective.mapping_rate.mate1,seqdetective.mapping_rate.mate2,seqdetective.nofeature_rate.mate1,seqdetective.nofeature_rate.mate2,seqdetective.sparsity.mate1,seqdetective.sparsity.mate2,seqdetective.pos_strand_rate.mate1,seqdetective.pos_strand_rate.mate2,seqdetective.readlen.mate1,seqdetective.readlen.mate2,seqdetective.judgement.mate1,seqdetective.judgement.mate2,seqdetective.judgement.reason,platform_family,instrument_generation,read_bias,selection_class,prep_kit,sc_or_bulk,tech_class,technology,tech_variant,submission.bioprojectsource.country,earliest_date,devstage_curation,devstage_curation_coarse,tissue_curation,tissue_curation_coarse 60007,SRR12109607,SRX8633610,SRS6920345,SRP269241,PRJNA641989,Zebrafish intestinal SmallRNA,PRJNA641989,Other,A model of streptococcus agalactiae infected zebrafish was established to determine intestinal small RNA of zebrafish.To explore the molecular mechanism of antibacterial immunity of zebrafish.,,,,,Drt3,,strain:Streptococcus agalactiae|age:adult|sex:male|tissue:gut|BioSampleModel:Model organism or animal,,,,,,,,,miRNA Seq of zebrafish intestine,F,F,BGISEQ,,,miRNA-Seq,TRANSCRIPTOMIC,RT-PCR,SINGLE,BGISEQ,BGISEQ-500,,SRP269241,,loader:fastq load.py,Drt3.fq.gz,fastq,953116651.0,39450392.0,Drt3.fq.gz,0:24.16,A:165275545;C:266933722;G:285524079;T:235383107;N:198,24,,,,165275545,266933722,285524079,235383107,198,SRX8633610,SRS6920345,SRA1092425,Kunming University of Science and Technology|faculty of life science and technology,Kunming University of Science and Technology,1,0.86243,,0.21541,,0.80294,,0.67181,,29,,B,,usable mapping rate,bgi,bgi,unknown,small_rna,unknown,bulk,unknown,unknown,,China,2020-07-10,Adult,Adult,Gut,Digestive System 60008,SRR12109608,SRX8633609,SRS6920344,SRP269241,PRJNA641989,Zebrafish intestinal SmallRNA,PRJNA641989,Other,A model of streptococcus agalactiae infected zebrafish was established to determine intestinal small RNA of zebrafish.To explore the molecular mechanism of antibacterial immunity of zebrafish.,,,,,Drt2,,strain:Streptococcus agalactiae|age:adult|sex:male|tissue:gut|BioSampleModel:Model organism or animal,,,,,,,,,miRNA Seq of zebrafish intestine,E,E,BGISEQ,,,miRNA-Seq,TRANSCRIPTOMIC,RT-PCR,SINGLE,BGISEQ,BGISEQ-500,,SRP269241,,loader:fastq load.py,Drt2.fq.gz,fastq,629335361.0,26037543.0,Drt2.fq.gz,0:24.17,A:111827613;C:172564695;G:192159133;T:152783892;N:28,24,,,,111827613,172564695,192159133,152783892,28,SRX8633609,SRS6920344,SRA1092425,Kunming University of Science and Technology|faculty of life science and technology,Kunming University of Science and Technology,1,0.86328,,0.21943,,0.7992,,0.64786,,26,,B,,usable mapping rate,bgi,bgi,unknown,small_rna,unknown,bulk,unknown,unknown,,China,2020-07-10,Adult,Adult,Gut,Digestive System 60009,SRR12109609,SRX8633608,SRS6920343,SRP269241,PRJNA641989,Zebrafish intestinal SmallRNA,PRJNA641989,Other,A model of streptococcus agalactiae infected zebrafish was established to determine intestinal small RNA of zebrafish.To explore the molecular mechanism of antibacterial immunity of zebrafish.,,,,,Drt1,,strain:Streptococcus agalactiae|age:adult|sex:male|tissue:gut|BioSampleModel:Model organism or animal,,,,,,,,,miRNA Seq of zebrafish intestine,D,D,BGISEQ,,,miRNA-Seq,TRANSCRIPTOMIC,RT-PCR,SINGLE,BGISEQ,BGISEQ-500,,SRP269241,,loader:fastq load.py,Drt1.fq.gz,fastq,898185854.0,37273958.0,Drt1.fq.gz,0:24.10,A:155257170;C:247725871;G:276963807;T:218238980;N:26,24,,,,155257170,247725871,276963807,218238980,26,SRX8633608,SRS6920343,SRA1092425,Kunming University of Science and Technology|faculty of life science and technology,Kunming University of Science and Technology,1,0.86686,,0.21764,,0.79508,,0.6694,,24,,B,,usable mapping rate,bgi,bgi,unknown,small_rna,unknown,bulk,unknown,unknown,,China,2020-07-10,Adult,Adult,Gut,Digestive System 60010,SRR12109610,SRX8633607,SRS6920342,SRP269241,PRJNA641989,Zebrafish intestinal SmallRNA,PRJNA641989,Other,A model of streptococcus agalactiae infected zebrafish was established to determine intestinal small RNA of zebrafish.To explore the molecular mechanism of antibacterial immunity of zebrafish.,,,,,Drc3,,strain:Streptococcus agalactiae|age:adult|sex:male|tissue:gut|BioSampleModel:Model organism or animal,,,,,,,,,miRNA Seq of zebrafish intestine,C,C,BGISEQ,,,miRNA-Seq,TRANSCRIPTOMIC,RT-PCR,SINGLE,BGISEQ,BGISEQ-500,,SRP269241,,loader:fastq load.py,Drc3.fq.gz,fastq,912782161.0,35931507.0,Drc3.fq.gz,0:25.40,A:153448479;C:252628189;G:280829895;T:225874586;N:1012,25,,,,153448479,252628189,280829895,225874586,1012,SRX8633607,SRS6920342,SRA1092425,Kunming University of Science and Technology|faculty of life science and technology,Kunming University of Science and Technology,1,0.89797,,0.21308,,0.80823,,0.62611,,23,,B,,usable mapping rate,bgi,bgi,unknown,small_rna,unknown,bulk,unknown,unknown,,China,2020-07-10,Adult,Adult,Gut,Digestive System 60011,SRR12109611,SRX8633606,SRS6920341,SRP269241,PRJNA641989,Zebrafish intestinal SmallRNA,PRJNA641989,Other,A model of streptococcus agalactiae infected zebrafish was established to determine intestinal small RNA of zebrafish.To explore the molecular mechanism of antibacterial immunity of zebrafish.,,,,,Drc2,,strain:Streptococcus agalactiae|age:adult|sex:male|tissue:gut|BioSampleModel:Model organism or animal,,,,,,,,,miRNA Seq of zebrafish intestine,B,B,BGISEQ,,,miRNA-Seq,TRANSCRIPTOMIC,RT-PCR,SINGLE,BGISEQ,BGISEQ-500,,SRP269241,,loader:fastq load.py,Drc2.fq.gz,fastq,784553020.0,31429473.0,Drc2.fq.gz,0:24.96,A:128271350;C:223302609;G:241310233;T:191668193;N:635,24,,,,128271350,223302609,241310233,191668193,635,SRX8633606,SRS6920341,SRA1092425,Kunming University of Science and Technology|faculty of life science and technology,Kunming University of Science and Technology,1,0.9087,,0.20487,,0.80805,,0.67324,,30,,B,,usable mapping rate,bgi,bgi,unknown,small_rna,unknown,bulk,unknown,unknown,,China,2020-07-10,Adult,Adult,Gut,Digestive System 60012,SRR12109612,SRX8633605,SRS6920340,SRP269241,PRJNA641989,Zebrafish intestinal SmallRNA,PRJNA641989,Other,A model of streptococcus agalactiae infected zebrafish was established to determine intestinal small RNA of zebrafish.To explore the molecular mechanism of antibacterial immunity of zebrafish.,,,,,Drc1,,strain:Streptococcus agalactiae|age:adult|sex:male|tissue:gut|BioSampleModel:Model organism or animal,,,,,,,,,miRNA Seq of zebrafish intestine,A,A,BGISEQ,,,miRNA-Seq,TRANSCRIPTOMIC,RT-PCR,SINGLE,BGISEQ,BGISEQ-500,,SRP269241,,loader:fastq load.py,Drc1.fq.gz,fastq,814894343.0,32234530.0,Drc1.fq.gz,0:25.28,A:133616147;C:230834630;G:253965304;T:196477437;N:825,25,,,,133616147,230834630,253965304,196477437,825,SRX8633605,SRS6920340,SRA1092425,Kunming University of Science and Technology|faculty of life science and technology,Kunming University of Science and Technology,1,0.89344,,0.21273,,0.80738,,0.66815,,28,,B,,usable mapping rate,bgi,bgi,unknown,small_rna,unknown,bulk,unknown,unknown,,China,2020-07-10,Adult,Adult,Gut,Digestive System 74161,SRR23576625,SRX19463432,SRS16856055,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M9,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M9,M9,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M9_1.fq.gz M9_2.fq.gz,fastq fastq,10791781600.0,107917816.0,M9 1.fq.gz,0:100 1:100,A:2848108353;C:2487301410;G:2561260439;T:2895111398;N:0,100,100,,,2848108353,2487301410,2561260439,2895111398,0,SRX19463432,SRS16856055,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95252,,0.05974,,0.79184,,0.6274,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74162,SRR23576626,SRX19463431,SRS16856054,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M8,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M8,M8,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M8_1.fq.gz M8_2.fq.gz,fastq fastq,10803624400.0,108036244.0,M8 1.fq.gz,0:100 1:100,A:2826927335;C:2516499907;G:2585204327;T:2874992831;N:0,100,100,,,2826927335,2516499907,2585204327,2874992831,0,SRX19463431,SRS16856054,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95494,,0.06268,,0.79139,,0.60873,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74163,SRR23576627,SRX19463430,SRS16856053,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M7,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M7,M7,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M7_1.fq.gz M7_2.fq.gz,fastq fastq,10794944600.0,107949446.0,M7 1.fq.gz,0:100 1:100,A:2822800001;C:2515936087;G:2583221720;T:2872986792;N:0,100,100,,,2822800001,2515936087,2583221720,2872986792,0,SRX19463430,SRS16856053,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95392,,0.0552,,0.78967,,0.61766,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74164,SRR23576628,SRX19463429,SRS16856052,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M6,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M6,M6,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M6_1.fq.gz M6_2.fq.gz,fastq fastq,10806717200.0,108067172.0,M6 1.fq.gz,0:100 1:100,A:2872422644;C:2476696362;G:2537205428;T:2920392766;N:0,100,100,,,2872422644,2476696362,2537205428,2920392766,0,SRX19463429,SRS16856052,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95383,,0.06563,,0.79293,,0.63948,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74165,SRR23576629,SRX19463428,SRS16856051,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M5,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M5,M5,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M5_1.fq.gz M5_2.fq.gz,fastq fastq,10553024000.0,105530240.0,M5 1.fq.gz,0:100 1:100,A:2756587901;C:2467885042;G:2531072385;T:2797478672;N:0,100,100,,,2756587901,2467885042,2531072385,2797478672,0,SRX19463428,SRS16856051,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95761,,0.05754,,0.79435,,0.61791,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74166,SRR23576630,SRX19463427,SRS16856048,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M4,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M4,M4,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M4_1.fq.gz M4_2.fq.gz,fastq fastq,10821109400.0,108211094.0,M4 1.fq.gz,0:100 1:100,A:2853720356;C:2500021520;G:2567460910;T:2899906614;N:0,100,100,,,2853720356,2500021520,2567460910,2899906614,0,SRX19463427,SRS16856048,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95171,,0.0636,,0.78644,,0.61061,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74174,SRR23576638,SRX19463419,SRS16856040,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M3,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M3,M3,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M3_1.fq.gz M3_2.fq.gz,fastq fastq,10811204400.0,108112044.0,M3 1.fq.gz,0:100 1:100,A:2826338851;C:2514522241;G:2594843889;T:2875499419;N:0,100,100,,,2826338851,2514522241,2594843889,2875499419,0,SRX19463419,SRS16856040,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95049,,0.05611,,0.79127,,0.60997,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74185,SRR23576649,SRX19463408,SRS16856031,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M2,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M2,M2,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M2_1.fq.gz M2_2.fq.gz,fastq fastq,10784874600.0,107848746.0,M2 1.fq.gz,0:100 1:100,A:2800268243;C:2532669517;G:2601088355;T:2850848485;N:0,100,100,,,2800268243,2532669517,2601088355,2850848485,0,SRX19463408,SRS16856031,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95513,,0.05808,,0.78171,,0.60306,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74186,SRR23576650,SRX19463407,SRS16856030,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M1,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M1,M1,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M1_1.fq.gz M1_2.fq.gz,fastq fastq,10797666400.0,107976664.0,M1 1.fq.gz,0:100 1:100,A:2818869037;C:2522566664;G:2592727107;T:2863503592;N:0,100,100,,,2818869037,2522566664,2592727107,2863503592,0,SRX19463407,SRS16856030,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95195,,0.06111,,0.78184,,0.6129,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System