rowid,run.accession,experiment.accession,sample.accession,study.accession,bioproject,study.title,study.alias,study.type,study.abstract,study.attributes,study.PMIDs,sample.description,sample.title,sample.alias,sample.centername,sample.attributes,GEOsample.title,GEOsample.dataprocessing,GEOsample.source,GEOsample.treatmentprotocol,GEOsample.extractprotocol,GEOsample.growthprotocol,GEOsample.characteristics,GEOsample.accession,experiment.title,experiment.alias,experiment.library_name,experiment.design_description,experiment.library_construction_protocol,experiment.attributes,experiment.library_strategy,experiment.library_source,experiment.library_selection,experiment.library_layout,experiment.platform,experiment.instrument_model,experiment.spot_descriptor,experiment.study_ref,run.title,run.attributes,run.filename,run.semantic_name,run.total_bases,run.total_spots,run.alias,run.read_lengths,run.base_counts,run.r1_length,run.r2_length,run.r3_length,run.r4_length,run.Acount,run.Ccount,run.Gcount,run.Tcount,run.Ncount,run.experiment,run.pool_member,submission.accession,submission.srasource,submission.bioprojectsource,seqdetective.n_mates,seqdetective.mapping_rate.mate1,seqdetective.mapping_rate.mate2,seqdetective.nofeature_rate.mate1,seqdetective.nofeature_rate.mate2,seqdetective.sparsity.mate1,seqdetective.sparsity.mate2,seqdetective.pos_strand_rate.mate1,seqdetective.pos_strand_rate.mate2,seqdetective.readlen.mate1,seqdetective.readlen.mate2,seqdetective.judgement.mate1,seqdetective.judgement.mate2,seqdetective.judgement.reason,platform_family,instrument_generation,read_bias,selection_class,prep_kit,sc_or_bulk,tech_class,technology,tech_variant,submission.bioprojectsource.country,earliest_date,devstage_curation,devstage_curation_coarse,tissue_curation,tissue_curation_coarse
7950,ERR015567,ERX005930,ERS000089,ERP000263,PRJEB2208,Zebrafish gene three prime end pull down for genome annotation,E-MTAB-308,Transcriptome Analysis,,,,RNA extracted from male adult zebrafish head,,SAMEA708835,SC,ENA FIRST PUBLIC:2010 02 26T10:44:13Z|ENA LAST UPDATE:2018 03 08T15:51:30Z|External Id:SAMEA708835|INSDC center name:SC|INSDC first public:2010 02 26T10:44:13Z|INSDC last update:2018 03 08T15:51:30Z|INSDC status:public|Submitter Id:ZF male head sample1|common name:zebrafish|sample name:ZF male head sample1|scientific name:Danio rerio|sex:male|strain:Tuebingen,,,,,,,,,Illumina Genome Analyzer II paired end sequencing; Zebrafish gene 3 prime end pull down for genome annotation,E MTAB 308:Illumina Genome Analyzer II sequencing of adult Zebrafish male head dpf three prime pull down paired end 250 to 300 bp insert,Zebrafish adult male head mRNA three prime end,Zebrafish gene three prime end pull down for genome annotation,20 ug of total RNA was fragmented using RNA Fragmentation Reagent Ambion for 5 minutes at 70 C and ethanol precipitated with glycogen and LiCl.   RNA was annealed to the oligo stBPM1polyT22 biotin GGCCAGTCCTGGAGTTTTTTTTTTTTTTTTTTTTTTVN and bound to streptavidin  magnetic beads.   post washing by pull down on a magnet  the bound RNA was reverse transcribed with SuperScript II Invitrogen and a second strand synthesised with DNA polymerase I Promega and RNase H NEB.   post further washing  the double strand cDNA was released from the beads with BpmI NEB.   The cDNA was recovered with the QIAgen PCR Purification Kit and made into a standard Illumina library following the manufacturer's protocol with a fragment size of 250 to 300 bp.,Experimental Factor: DEVELOPMENTAL STAGE:adult|Experimental Factor: ORGANISM PART:head|Experimental Factor: SEX:male,RNA-Seq,TRANSCRIPTOMIC,other,PAIRED,ILLUMINA,Illumina Genome Analyzer II,,ERP000263,Illumina Genome Analyzer II paired end sequencing; Zebrafish gene three prime end pull down for genome annotation,ENA FIRST PUBLIC:2010 08 19|ENA LAST UPDATE:2018 11 16,3444_7.srf,srf,1384012896.0,9105348.0,E MTAB 308:Illumina Genome Analyzer II sequencing of adult Zebrafish male head dpf three prime pull down paired end 250 to 300 bp insert,0:76 1:76,A:369912216;C:306963547;G:292249178;T:392053840;N:22834115,76,76,,,369912216,306963547,292249178,392053840,22834115,ERX005930,ERS000089,ERA010603,SC|Wellcome Trust Sanger Institute,SC|Wellcome Trust Sanger Institute,2,0.95932,0.96084,0.20719,0.21321,0.73959,0.74763,0.47227,0.48033,76,76,B,B,biological fallback assumption,illumina,early_illumina,3prime,other,unknown,bulk,unknown,unknown,,United Kingdom,2010-02-26,Adult,Adult,Head,Nervous System
10407,ERR9077202,ERX8620336,ERS10857224,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT5S8,SAMEA13254181,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254181|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT5S8|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT5S8|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT5S8 s,Sv2aWT5S8 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT5S8L001-1.fastq.gz,fastq,652046291.0,8633105.0,E MTAB 11505:sv2aWT5S8L001,0:75.53 1:0,A:159570243;C:156420495;G:154853315;T:181073030;N:129208,75,0,,,159570243,156420495,154853315,181073030,129208,ERX8620336,ERS10857224,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95245,,0.1148,,0.65756,,0.47011,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10408,ERR9077203,ERX8620336,ERS10857224,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT5S8,SAMEA13254181,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254181|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT5S8|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT5S8|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT5S8 s,Sv2aWT5S8 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT5S8L002-1.fastq.gz,fastq,653840525.0,8656886.0,E MTAB 11505:sv2aWT5S8L002,0:75.53 1:0,A:159902458;C:156826842;G:155509070;T:181475104;N:127051,75,0,,,159902458,156826842,155509070,181475104,127051,ERX8620336,ERS10857224,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95226,,0.1156,,0.65792,,0.4667,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10409,ERR9077204,ERX8620336,ERS10857224,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT5S8,SAMEA13254181,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254181|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT5S8|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT5S8|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT5S8 s,Sv2aWT5S8 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT5S8L003-1.fastq.gz,fastq,659584196.0,8732885.0,E MTAB 11505:sv2aWT5S8L003,0:75.53 1:0,A:161257146;C:158299734;G:156793443;T:183128972;N:104901,75,0,,,161257146,158299734,156793443,183128972,104901,ERX8620336,ERS10857224,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95298,,0.11485,,0.65798,,0.46853,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10410,ERR9077205,ERX8620336,ERS10857224,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT5S8,SAMEA13254181,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254181|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT5S8|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT5S8|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT5S8 s,Sv2aWT5S8 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT5S8L004-1.fastq.gz,fastq,666627746.0,8826123.0,E MTAB 11505:sv2aWT5S8L004,0:75.53 1:0,A:162975131;C:159937258;G:158506242;T:185106149;N:102966,75,0,,,162975131,159937258,158506242,185106149,102966,ERX8620336,ERS10857224,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.9531,,0.11425,,0.65736,,0.47309,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10411,ERR9077198,ERX8620335,ERS10857223,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT4S7,SAMEA13254180,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254180|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT4S7|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT4S7|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT4S7 s,Sv2aWT4S7 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT4S7L001-1.fastq.gz,fastq,683751258.0,9051795.0,E MTAB 11505:sv2aWT4S7L001,0:75.54 1:0,A:162889923;C:167127644;G:164779384;T:188822907;N:131400,75,0,,,162889923,167127644,164779384,188822907,131400,ERX8620335,ERS10857223,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95739,,0.0959,,0.6606,,0.46826,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10412,ERR9077199,ERX8620335,ERS10857223,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT4S7,SAMEA13254180,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254180|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT4S7|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT4S7|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT4S7 s,Sv2aWT4S7 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT4S7L002-1.fastq.gz,fastq,684187711.0,9057591.0,E MTAB 11505:sv2aWT4S7L002,0:75.54 1:0,A:162923879;C:167246213;G:165071145;T:188818774;N:127700,75,0,,,162923879,167246213,165071145,188818774,127700,ERX8620335,ERS10857223,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95724,,0.0959,,0.66036,,0.47026,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10413,ERR9077200,ERX8620335,ERS10857223,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT4S7,SAMEA13254180,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254180|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT4S7|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT4S7|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT4S7 s,Sv2aWT4S7 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT4S7L003-1.fastq.gz,fastq,692320213.0,9165132.0,E MTAB 11505:sv2aWT4S7L003,0:75.54 1:0,A:164772792;C:169329920;G:166952052;T:191164422;N:101027,75,0,,,164772792,169329920,166952052,191164422,101027,ERX8620335,ERS10857223,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95786,,0.09701,,0.66131,,0.47564,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10414,ERR9077201,ERX8620335,ERS10857223,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT4S7,SAMEA13254180,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254180|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT4S7|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT4S7|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT4S7 s,Sv2aWT4S7 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT4S7L004-1.fastq.gz,fastq,697047881.0,9227702.0,E MTAB 11505:sv2aWT4S7L004,0:75.54 1:0,A:165881728;C:170388393;G:168105900;T:192572068;N:99792,75,0,,,165881728,170388393,168105900,192572068,99792,ERX8620335,ERS10857223,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.9584,,0.09565,,0.66115,,0.46967,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10415,ERR9077194,ERX8620334,ERS10857222,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT3S2,SAMEA13254179,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254179|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT3S2|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT3S2|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT3S2 s,Sv2aWT3S2 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT3S2L001-1.fastq.gz,fastq,723508205.0,9579193.0,E MTAB 11505:sv2aWT3S2L001,0:75.53 1:0,A:177832489;C:174193135;G:169978598;T:201360184;N:143799,75,0,,,177832489,174193135,169978598,201360184,143799,ERX8620334,ERS10857222,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95218,,0.11732,,0.65916,,0.47955,,71,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10416,ERR9077195,ERX8620334,ERS10857222,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT3S2,SAMEA13254179,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254179|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT3S2|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT3S2|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT3S2 s,Sv2aWT3S2 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT3S2L002-1.fastq.gz,fastq,726190024.0,9614674.0,E MTAB 11505:sv2aWT3S2L002,0:75.53 1:0,A:178408224;C:174776263;G:170820745;T:202047224;N:137568,75,0,,,178408224,174776263,170820745,202047224,137568,ERX8620334,ERS10857222,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95093,,0.11567,,0.65865,,0.46877,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10417,ERR9077196,ERX8620334,ERS10857222,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT3S2,SAMEA13254179,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254179|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT3S2|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT3S2|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT3S2 s,Sv2aWT3S2 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT3S2L003-1.fastq.gz,fastq,735499955.0,9737845.0,E MTAB 11505:sv2aWT3S2L003,0:75.53 1:0,A:180659962;C:177141362;G:172905323;T:204678308;N:115000,75,0,,,180659962,177141362,172905323,204678308,115000,ERX8620334,ERS10857222,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95233,,0.11614,,0.65898,,0.47114,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10418,ERR9077197,ERX8620334,ERS10857222,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT3S2,SAMEA13254179,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254179|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT3S2|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT3S2|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT3S2 s,Sv2aWT3S2 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT3S2L004-1.fastq.gz,fastq,745285512.0,9867337.0,E MTAB 11505:sv2aWT3S2L004,0:75.53 1:0,A:183067487;C:179408382;G:175250814;T:207445912;N:112917,75,0,,,183067487,179408382,175250814,207445912,112917,ERX8620334,ERS10857222,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95245,,0.11655,,0.65857,,0.47087,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10419,ERR9077190,ERX8620333,ERS10857221,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT1S1,SAMEA13254178,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254178|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT1S1|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT1S1|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT1S1 s,Sv2aWT1S1 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT1S1L001-1.fastq.gz,fastq,647414748.0,8571883.0,E MTAB 11505:sv2aWT1S1L001,0:75.53 1:0,A:154593859;C:160498057;G:153809612;T:178389112;N:124108,75,0,,,154593859,160498057,153809612,178389112,124108,ERX8620333,ERS10857221,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95955,,0.08686,,0.65955,,0.47406,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10420,ERR9077191,ERX8620333,ERS10857221,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT1S1,SAMEA13254178,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254178|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT1S1|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT1S1|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT1S1 s,Sv2aWT1S1 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT1S1L002-1.fastq.gz,fastq,646657758.0,8561861.0,E MTAB 11505:sv2aWT1S1L002,0:75.53 1:0,A:154348044;C:160294625;G:153804048;T:178092212;N:118829,75,0,,,154348044,160294625,153804048,178092212,118829,ERX8620333,ERS10857221,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95942,,0.08632,,0.65991,,0.47539,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10421,ERR9077192,ERX8620333,ERS10857221,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT1S1,SAMEA13254178,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254178|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT1S1|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT1S1|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT1S1 s,Sv2aWT1S1 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT1S1L003-1.fastq.gz,fastq,654781451.0,8669333.0,E MTAB 11505:sv2aWT1S1L003,0:75.53 1:0,A:156252744;C:162396721;G:155681450;T:180352911;N:97625,75,0,,,156252744,162396721,155681450,180352911,97625,ERX8620333,ERS10857221,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95972,,0.08498,,0.66137,,0.47457,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10422,ERR9077193,ERX8620333,ERS10857221,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aWT1S1,SAMEA13254178,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254178|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aWT1S1|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/+|individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aWT1S1|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aWT1S1 s,Sv2aWT1S1 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/+,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aWT1S1L004-1.fastq.gz,fastq,659716937.0,8734618.0,E MTAB 11505:sv2aWT1S1L004,0:75.53 1:0,A:157367211;C:163585842;G:156911139;T:181757809;N:94936,75,0,,,157367211,163585842,156911139,181757809,94936,ERX8620333,ERS10857221,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95985,,0.08585,,0.65857,,0.47349,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10423,ERR9077186,ERX8620332,ERS10857220,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO6S12,SAMEA13254177,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254177|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO6S12|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO6S12|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO6S12 s,Sv2aHO6S12 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO6S12L001-1.fastq.gz,fastq,675018261.0,8937958.0,E MTAB 11505:sv2aHO6S12L001,0:75.52 1:0,A:166564263;C:160539328;G:160003980;T:187773509;N:137181,75,0,,,166564263,160539328,160003980,187773509,137181,ERX8620332,ERS10857220,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94964,,0.13009,,0.65413,,0.47079,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10424,ERR9077187,ERX8620332,ERS10857220,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO6S12,SAMEA13254177,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254177|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO6S12|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO6S12|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO6S12 s,Sv2aHO6S12 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO6S12L002-1.fastq.gz,fastq,672995667.0,8911161.0,E MTAB 11505:sv2aHO6S12L002,0:75.52 1:0,A:165990319;C:160039398;G:159722501;T:187108781;N:134668,75,0,,,165990319,160039398,159722501,187108781,134668,ERX8620332,ERS10857220,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94837,,0.13029,,0.65744,,0.47959,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10425,ERR9077188,ERX8620332,ERS10857220,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO6S12,SAMEA13254177,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254177|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO6S12|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO6S12|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO6S12 s,Sv2aHO6S12 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO6S12L003-1.fastq.gz,fastq,683276767.0,9047147.0,E MTAB 11505:sv2aHO6S12L003,0:75.52 1:0,A:168501690;C:162583852;G:162063190;T:190018001;N:110034,75,0,,,168501690,162583852,162063190,190018001,110034,ERX8620332,ERS10857220,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94983,,0.13248,,0.6565,,0.47977,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10426,ERR9077189,ERX8620332,ERS10857220,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO6S12,SAMEA13254177,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254177|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO6S12|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO6S12|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO6S12 s,Sv2aHO6S12 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO6S12L004-1.fastq.gz,fastq,686469910.0,9089431.0,E MTAB 11505:sv2aHO6S12L004,0:75.52 1:0,A:169287189;C:163276361;G:162844724;T:190954218;N:107418,75,0,,,169287189,163276361,162844724,190954218,107418,ERX8620332,ERS10857220,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95061,,0.13029,,0.65389,,0.48044,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10427,ERR9077182,ERX8620331,ERS10857219,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO4S10,SAMEA13254176,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254176|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO4S10|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO4S10|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO4S10 s,Sv2aHO4S10 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO4S10L001-1.fastq.gz,fastq,713858966.0,9452474.0,E MTAB 11505:sv2aHO4S10L001,0:75.52 1:0,A:177913695;C:169425317;G:167540012;T:198835532;N:144410,75,0,,,177913695,169425317,167540012,198835532,144410,ERX8620331,ERS10857219,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94848,,0.12981,,0.6636,,0.47772,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10428,ERR9077183,ERX8620331,ERS10857219,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO4S10,SAMEA13254176,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254176|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO4S10|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO4S10|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO4S10 s,Sv2aHO4S10 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO4S10L002-1.fastq.gz,fastq,717619593.0,9502301.0,E MTAB 11505:sv2aHO4S10L002,0:75.52 1:0,A:178830542;C:170284720;G:168594514;T:199773382;N:136435,75,0,,,178830542,170284720,168594514,199773382,136435,ERX8620331,ERS10857219,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94812,,0.12868,,0.6645,,0.47281,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10429,ERR9077184,ERX8620331,ERS10857219,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO4S10,SAMEA13254176,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254176|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO4S10|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO4S10|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO4S10 s,Sv2aHO4S10 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO4S10L003-1.fastq.gz,fastq,727263626.0,9629858.0,E MTAB 11505:sv2aHO4S10L003,0:75.52 1:0,A:181201278;C:172619520;G:170780953;T:202550397;N:111478,75,0,,,181201278,172619520,170780953,202550397,111478,ERX8620331,ERS10857219,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94768,,0.12827,,0.66596,,0.47332,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10430,ERR9077185,ERX8620331,ERS10857219,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO4S10,SAMEA13254176,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254176|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO4S10|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO4S10|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO4S10 s,Sv2aHO4S10 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO4S10L004-1.fastq.gz,fastq,736595278.0,9753337.0,E MTAB 11505:sv2aHO4S10L004,0:75.52 1:0,A:183510872;C:174806534;G:173027794;T:205140640;N:109438,75,0,,,183510872,174806534,173027794,205140640,109438,ERX8620331,ERS10857219,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94925,,0.12904,,0.66417,,0.47297,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10431,ERR9077178,ERX8620330,ERS10857218,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO3S6,SAMEA13254175,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254175|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO3S6|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO3S6|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO3S6 s,Sv2aHO3S6 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO3S6L001-1.fastq.gz,fastq,710756305.0,9410862.0,E MTAB 11505:sv2aHO3S6L001,0:75.53 1:0,A:175585613;C:170261120;G:166658917;T:198106388;N:144267,75,0,,,175585613,170261120,166658917,198106388,144267,ERX8620330,ERS10857218,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94827,,0.14002,,0.66785,,0.474,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10432,ERR9077179,ERX8620330,ERS10857218,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO3S6,SAMEA13254175,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254175|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO3S6|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO3S6|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO3S6 s,Sv2aHO3S6 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO3S6L002-1.fastq.gz,fastq,715330324.0,9471415.0,E MTAB 11505:sv2aHO3S6L002,0:75.53 1:0,A:176679775;C:171311031;G:167903237;T:199299483;N:136798,75,0,,,176679775,171311031,167903237,199299483,136798,ERX8620330,ERS10857218,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.9469,,0.13915,,0.67004,,0.47654,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10433,ERR9077180,ERX8620330,ERS10857218,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO3S6,SAMEA13254175,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254175|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO3S6|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO3S6|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO3S6 s,Sv2aHO3S6 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO3S6L003-1.fastq.gz,fastq,722810562.0,9570364.0,E MTAB 11505:sv2aHO3S6L003,0:75.53 1:0,A:178442845;C:173192786;G:169595085;T:201465522;N:114324,75,0,,,178442845,173192786,169595085,201465522,114324,ERX8620330,ERS10857218,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94918,,0.13979,,0.66902,,0.47572,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10434,ERR9077181,ERX8620330,ERS10857218,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHO3S6,SAMEA13254175,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254175|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHO3S6|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a / |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHO3S6|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHO3S6 s,Sv2aHO3S6 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHO3S6L004-1.fastq.gz,fastq,732990507.0,9705054.0,E MTAB 11505:sv2aHO3S6L004,0:75.53 1:0,A:180951130;C:175567778;G:172037542;T:204323488;N:110569,75,0,,,180951130,175567778,172037542,204323488,110569,ERX8620330,ERS10857218,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.94812,,0.13893,,0.67085,,0.47502,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10435,ERR9077174,ERX8620329,ERS10857217,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET7S9,SAMEA13254174,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254174|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET7S9|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET7S9|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET7S9 s,Sv2aHET7S9 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET7S9L001-1.fastq.gz,fastq,773209432.0,10238087.0,E MTAB 11505:sv2aHET7S9L001,0:75.52 1:0,A:191962953;C:184699376;G:180774008;T:215620759;N:152336,75,0,,,191962953,184699376,180774008,215620759,152336,ERX8620329,ERS10857217,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95047,,0.12485,,0.65705,,0.4775,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10436,ERR9077175,ERX8620329,ERS10857217,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET7S9,SAMEA13254174,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254174|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET7S9|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET7S9|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET7S9 s,Sv2aHET7S9 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET7S9L002-1.fastq.gz,fastq,773106152.0,10236677.0,E MTAB 11505:sv2aHET7S9L002,0:75.52 1:0,A:191812833;C:184676419;G:180997547;T:215473732;N:145621,75,0,,,191812833,184676419,180997547,215473732,145621,ERX8620329,ERS10857217,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95016,,0.12464,,0.65482,,0.47419,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10437,ERR9077176,ERX8620329,ERS10857217,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET7S9,SAMEA13254174,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254174|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET7S9|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET7S9|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET7S9 s,Sv2aHET7S9 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET7S9L003-1.fastq.gz,fastq,783061051.0,10368445.0,E MTAB 11505:sv2aHET7S9L003,0:75.52 1:0,A:194289152;C:187108364;G:183177036;T:218370500;N:115999,75,0,,,194289152,187108364,183177036,218370500,115999,ERX8620329,ERS10857217,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95172,,0.12488,,0.65445,,0.48157,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10438,ERR9077177,ERX8620329,ERS10857217,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET7S9,SAMEA13254174,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254174|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET7S9|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET7S9|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET7S9 s,Sv2aHET7S9 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET7S9L004-1.fastq.gz,fastq,790150025.0,10462214.0,E MTAB 11505:sv2aHET7S9L004,0:75.52 1:0,A:196056500;C:188746833;G:184927588;T:220305922;N:113182,75,0,,,196056500,188746833,184927588,220305922,113182,ERX8620329,ERS10857217,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95285,,0.12478,,0.65551,,0.4763,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10439,ERR9077170,ERX8620328,ERS10857216,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET4S5,SAMEA13254173,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254173|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET4S5|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET4S5|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET4S5 s,Sv2aHET4S5 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET4S5L001-1.fastq.gz,fastq,685650097.0,9076481.0,E MTAB 11505:sv2aHET4S5L001,0:75.54 1:0,A:161812875;C:167870520;G:166985310;T:188850530;N:130862,75,0,,,161812875,167870520,166985310,188850530,130862,ERX8620328,ERS10857216,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95733,,0.09974,,0.65691,,0.47392,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10440,ERR9077171,ERX8620328,ERS10857216,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET4S5,SAMEA13254173,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254173|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET4S5|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET4S5|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET4S5 s,Sv2aHET4S5 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET4S5L002-1.fastq.gz,fastq,684402241.0,9059974.0,E MTAB 11505:sv2aHET4S5L002,0:75.54 1:0,A:161493428;C:167520248;G:166882054;T:188383816;N:122695,75,0,,,161493428,167520248,166882054,188383816,122695,ERX8620328,ERS10857216,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95537,,0.09915,,0.65719,,0.48261,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10441,ERR9077172,ERX8620328,ERS10857216,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET4S5,SAMEA13254173,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254173|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET4S5|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET4S5|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET4S5 s,Sv2aHET4S5 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET4S5L003-1.fastq.gz,fastq,694099126.0,9188245.0,E MTAB 11505:sv2aHET4S5L003,0:75.54 1:0,A:163727378;C:169989210;G:169143224;T:191137588;N:101726,75,0,,,163727378,169989210,169143224,191137588,101726,ERX8620328,ERS10857216,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95629,,0.09861,,0.65705,,0.47187,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10442,ERR9077173,ERX8620328,ERS10857216,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET4S5,SAMEA13254173,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254173|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET4S5|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET4S5|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET4S5 s,Sv2aHET4S5 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET4S5L004-1.fastq.gz,fastq,698753836.0,9249820.0,E MTAB 11505:sv2aHET4S5L004,0:75.54 1:0,A:164809473;C:171057633;G:170349692;T:192441413;N:95625,75,0,,,164809473,171057633,170349692,192441413,95625,ERX8620328,ERS10857216,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95613,,0.09885,,0.65798,,0.47227,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10443,ERR9077166,ERX8620327,ERS10857215,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET3S4,SAMEA13254172,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254172|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET3S4|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET3S4|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET3S4 s,Sv2aHET3S4 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET3S4L001-1.fastq.gz,fastq,691298605.0,9151512.0,E MTAB 11505:sv2aHET3S4L001,0:75.54 1:0,A:164743919;C:170752099;G:164763621;T:190912044;N:126922,75,0,,,164743919,170752099,164763621,190912044,126922,ERX8620327,ERS10857215,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95684,,0.09604,,0.6603,,0.47285,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10444,ERR9077167,ERX8620327,ERS10857215,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET3S4,SAMEA13254172,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254172|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET3S4|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET3S4|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET3S4 s,Sv2aHET3S4 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET3S4L002-1.fastq.gz,fastq,694080975.0,9188259.0,E MTAB 11505:sv2aHET3S4L002,0:75.54 1:0,A:165336810;C:171397273;G:165632321;T:191591872;N:122699,75,0,,,165336810,171397273,165632321,191591872,122699,ERX8620327,ERS10857215,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95612,,0.09694,,0.65993,,0.46918,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10445,ERR9077168,ERX8620327,ERS10857215,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET3S4,SAMEA13254172,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254172|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET3S4|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET3S4|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET3S4 s,Sv2aHET3S4 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET3S4L003-1.fastq.gz,fastq,703689889.0,9315387.0,E MTAB 11505:sv2aHET3S4L003,0:75.54 1:0,A:167575230;C:173881977;G:167845574;T:194289403;N:97705,75,0,,,167575230,173881977,167845574,194289403,97705,ERX8620327,ERS10857215,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.9577,,0.09608,,0.66042,,0.47022,,74,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10446,ERR9077169,ERX8620327,ERS10857215,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET3S4,SAMEA13254172,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254172|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET3S4|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET3S4|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET3S4 s,Sv2aHET3S4 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET3S4L004-1.fastq.gz,fastq,712116538.0,9426961.0,E MTAB 11505:sv2aHET3S4L004,0:75.54 1:0,A:169598596;C:175885948;G:169866534;T:196669400;N:96060,75,0,,,169598596,175885948,169866534,196669400,96060,ERX8620327,ERS10857215,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95734,,0.09716,,0.66054,,0.47257,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10447,ERR9077162,ERX8620326,ERS10857214,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET2S3,SAMEA13254171,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254171|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET2S3|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET2S3|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET2S3 s,Sv2aHET2S3 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET2S3L001-1.fastq.gz,fastq,733440522.0,9709422.0,E MTAB 11505:sv2aHET2S3L001,0:75.54 1:0,A:173670000;C:181175353;G:175392793;T:203059256;N:143120,75,0,,,173670000,181175353,175392793,203059256,143120,ERX8620326,ERS10857214,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95885,,0.08758,,0.65393,,0.47249,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10448,ERR9077163,ERX8620326,ERS10857214,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET2S3,SAMEA13254171,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254171|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET2S3|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET2S3|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET2S3 s,Sv2aHET2S3 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET2S3L002-1.fastq.gz,fastq,732121929.0,9691967.0,E MTAB 11505:sv2aHET2S3L002,0:75.54 1:0,A:173332091;C:180805738;G:175271736;T:202574727;N:137637,75,0,,,173332091,180805738,175271736,202574727,137637,ERX8620326,ERS10857214,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95775,,0.08879,,0.6564,,0.4718,,76,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10449,ERR9077164,ERX8620326,ERS10857214,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET2S3,SAMEA13254171,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254171|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET2S3|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET2S3|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET2S3 s,Sv2aHET2S3 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET2S3L003-1.fastq.gz,fastq,743488189.0,9842286.0,E MTAB 11505:sv2aHET2S3L003,0:75.54 1:0,A:175979238;C:183726319;G:177933958;T:205735955;N:112719,75,0,,,175979238,183726319,177933958,205735955,112719,ERX8620326,ERS10857214,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.9593,,0.08716,,0.65437,,0.46976,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
10450,ERR9077165,ERX8620326,ERS10857214,ERP135966,PRJEB51339,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E-MTAB-11505,Transcriptome Analysis,Transcriptome analysis of the heads of 6 dpf sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,,Protocols: 6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Sv2aHET2S3,SAMEA13254171,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg",ENA first public:2022 04 21|ENA last update:2022 04 21|External Id:SAMEA13254171|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven  Campus Gasthuisberg|INSDC first public:2022 04 21T00:32:07Z|INSDC last update:2022 04 21T00:32:07Z|INSDC status:public|Submitter Id:E MTAB 11505:Sv2aHET2S3|age:6|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:sv2a+/ |individual:pool of 10 heads|organism part:head|sample name:E MTAB 11505:Sv2aHET2S3|sex:not available|strain:AB,,,,,,,,,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,E MTAB 11505:Sv2aHET2S3 s,Sv2aHET2S3 s,RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,6 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled per sample. Total RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas.  TruSeq RNA Seq sample preparation kit was used to prepare sequencing library of mRNA in accordance with the manufacturer guidelines.,Experimental Factor: genotype:sv2a+/ ,RNA-Seq,TRANSCRIPTOMIC,PolyA,SINGLE,ILLUMINA,NextSeq 500,,ERP135966,NextSeq 500 sequencing; RNA seq experiment of sv2a /   sv2a+/  and sv2a+/+ zebrafish larvae,ENA FIRST PUBLIC:2022 04 21|ENA LAST UPDATE:2022 04 21,sv2aHET2S3L004-1.fastq.gz,fastq,747723481.0,9898304.0,E MTAB 11505:sv2aHET2S3L004,0:75.54 1:0,A:176935451;C:184684782;G:179046040;T:206946124;N:111084,75,0,,,176935451,184684782,179046040,206946124,111084,ERX8620326,ERS10857214,ERA9644804,"Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven, Campus Gasthuisberg|European Nucleotide Archive",1,0.95934,,0.08676,,0.65533,,0.47523,,75,,B,,usable mapping rate,illumina,nextseq,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-04-21,Larval,Larval,Head,Nervous System
11025,ERR9787516,ERX9334792,ERS12088364,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 9,SAMEA14460887,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460887|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:24Z|INSDC last update:2022 09 12T12:19:24Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 9|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 9|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 9 p,Sample 9 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,TSCHOM1_1.fastq.gz TSCHOM1_2.fastq.gz,fastq fastq,6360351174.0,31486887.0,E MTAB 11776:TSCHOM1 ,0:101 1:101,A:1750731340;C:1410426576;G:1460021447;T:1739131898;N:39913,101,101,,,1750731340,1410426576,1460021447,1739131898,39913,ERX9334792,ERS12088364,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93517,0.92417,0.15551,0.15199,0.67736,0.6786,0.48763,0.48988,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11026,ERR9787515,ERX9334791,ERS12088363,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 8,SAMEA14460886,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460886|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:24Z|INSDC last update:2022 09 12T12:19:24Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 8|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 8|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 8 p,Sample 8 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,DEPHOM4_1.fastq.gz DEPHOM4_2.fastq.gz,fastq fastq,6195443828.0,30670514.0,E MTAB 11776:DEPHOM4 ,0:101 1:101,A:1524344281;C:1573560980;G:1585093004;T:1512406843;N:38720,101,101,,,1524344281,1573560980,1585093004,1512406843,38720,ERX9334791,ERS12088363,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.95088,0.9542,0.17631,0.17203,0.71121,0.70981,0.56015,0.57999,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11027,ERR9787514,ERX9334790,ERS12088362,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 7,SAMEA14460885,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460885|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 7|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 7|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 7 p,Sample 7 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,DEPHOM7_1.fastq.gz DEPHOM7_2.fastq.gz,fastq fastq,6201660378.0,30701289.0,E MTAB 11776:DEPHOM7 ,0:101 1:101,A:1699906420;C:1382805098;G:1427335171;T:1691574092;N:39597,101,101,,,1699906420,1382805098,1427335171,1691574092,39597,ERX9334790,ERS12088362,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.92781,0.92603,0.15556,0.15416,0.67965,0.67963,0.48209,0.48229,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11028,ERR9787513,ERX9334789,ERS12088361,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 6,SAMEA14460884,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460884|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 6|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 6|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 6 p,Sample 6 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,DEPHOM6_1.fastq.gz DEPHOM6_2.fastq.gz,fastq fastq,6255857382.0,30969591.0,E MTAB 11776:DEPHOM6 ,0:101 1:101,A:1722554517;C:1398134491;G:1424183345;T:1710945949;N:39080,101,101,,,1722554517,1398134491,1424183345,1710945949,39080,ERX9334789,ERS12088361,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93476,0.93206,0.16121,0.1592,0.67882,0.67898,0.48043,0.47851,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11029,ERR9787512,ERX9334788,ERS12088360,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 5,SAMEA14460883,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460883|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 5|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 5|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 5 p,Sample 5 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,DEPHOM1_1.fastq.gz DEPHOM1_2.fastq.gz,fastq fastq,6340417006.0,31388203.0,E MTAB 11776:DEPHOM1 ,0:101 1:101,A:1738622221;C:1420060351;G:1455477148;T:1726216833;N:40453,101,101,,,1738622221,1420060351,1455477148,1726216833,40453,ERX9334788,ERS12088360,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93634,0.93167,0.15036,0.14813,0.67809,0.67813,0.47978,0.47851,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11030,ERR9787511,ERX9334787,ERS12088359,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 4,SAMEA14460882,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460882|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 4|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 /  x tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 4|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 4 p,Sample 4 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 /  x tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,2XHOM7_1.fastq.gz 2XHOM7_2.fastq.gz,fastq fastq,6291880446.0,31147923.0,E MTAB 11776:2XHOM7 ,0:101 1:101,A:1712784902;C:1424143534;G:1452943449;T:1701969086;N:39475,101,101,,,1712784902,1424143534,1452943449,1701969086,39475,ERX9334787,ERS12088359,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93869,0.93511,0.15405,0.15042,0.67377,0.67351,0.50599,0.50683,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11031,ERR9787510,ERX9334786,ERS12088358,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 3,SAMEA14460881,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460881|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 3|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 /  x tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 3|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 3 p,Sample 3 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 /  x tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,2XHOM6_1.fastq.gz 2XHOM6_2.fastq.gz,fastq fastq,6214327596.0,30763998.0,E MTAB 11776:2XHOM6 ,0:101 1:101,A:1705019759;C:1384064144;G:1432455427;T:1692749964;N:38302,101,101,,,1705019759,1384064144,1432455427,1692749964,38302,ERX9334786,ERS12088358,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93591,0.92636,0.14492,0.14145,0.67489,0.67491,0.47753,0.49286,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11032,ERR9787509,ERX9334785,ERS12088357,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 2,SAMEA14460880,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460880|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 2|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 /  x tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 2|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 2 p,Sample 2 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 /  x tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,2XHOM4_1.fastq.gz 2XHOM4_2.fastq.gz,fastq fastq,6301691990.0,31196495.0,E MTAB 11776:2XHOM4 ,0:101 1:101,A:1698118705;C:1442276237;G:1473988715;T:1687268823;N:39510,101,101,,,1698118705,1442276237,1473988715,1687268823,39510,ERX9334785,ERS12088357,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.94255,0.93839,0.13232,0.13007,0.67326,0.67294,0.49084,0.49291,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11033,ERR9787508,ERX9334784,ERS12088356,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 16,SAMEA14460879,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460879|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 16|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:wild type genotype|individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 16|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 16 p,Sample 16 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:wild type genotype,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,WT7_1.fastq.gz WT7_2.fastq.gz,fastq fastq,6206666746.0,30726073.0,E MTAB 11776:WT7 ,0:101 1:101,A:1705689174;C:1387290312;G:1420249657;T:1693397929;N:39674,101,101,,,1705689174,1387290312,1420249657,1693397929,39674,ERX9334784,ERS12088356,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93493,0.92964,0.15803,0.1554,0.67405,0.67501,0.47988,0.46768,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11034,ERR9787507,ERX9334783,ERS12088355,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 15,SAMEA14460878,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460878|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 15|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:wild type genotype|individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 15|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 15 p,Sample 15 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:wild type genotype,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,WT6_1.fastq.gz WT6_2.fastq.gz,fastq fastq,6360740630.0,31488815.0,E MTAB 11776:WT6 ,0:101 1:101,A:1735195643;C:1436805269;G:1469558083;T:1719141699;N:39936,101,101,,,1735195643,1436805269,1469558083,1719141699,39936,ERX9334783,ERS12088355,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93629,0.93343,0.15169,0.1501,0.67572,0.67517,0.47499,0.47879,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11035,ERR9787506,ERX9334782,ERS12088354,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 14,SAMEA14460877,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460877|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 14|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:wild type genotype|individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 14|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 14 p,Sample 14 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:wild type genotype,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,WT4_1.fastq.gz WT4_2.fastq.gz,fastq fastq,6227472342.0,30829071.0,E MTAB 11776:WT4 ,0:101 1:101,A:1668352581;C:1434152947;G:1468645621;T:1656281986;N:39207,101,101,,,1668352581,1434152947,1468645621,1656281986,39207,ERX9334782,ERS12088354,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.94261,0.93675,0.15334,0.15049,0.67927,0.67872,0.48762,0.49138,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11036,ERR9787505,ERX9334781,ERS12088353,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 13,SAMEA14460876,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460876|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 13|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:wild type genotype|individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 13|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 13 p,Sample 13 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:wild type genotype,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,WT1_1.fastq.gz WT1_2.fastq.gz,fastq fastq,6332757570.0,31350285.0,E MTAB 11776:WT1 ,0:101 1:101,A:1726838066;C:1431452165;G:1460746594;T:1713681043;N:39702,101,101,,,1726838066,1431452165,1460746594,1713681043,39702,ERX9334781,ERS12088353,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.92422,0.93556,0.14884,0.14926,0.67694,0.67564,0.48223,0.48884,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11037,ERR9787504,ERX9334780,ERS12088352,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 12,SAMEA14460875,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460875|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 12|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 12|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 12 p,Sample 12 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,TSCHOM7_1.fastq.gz TSCHOM7_2.fastq.gz,fastq fastq,6216990360.0,30777180.0,E MTAB 11776:TSCHOM7 ,0:101 1:101,A:1710256020;C:1390027205;G:1419250792;T:1697417099;N:39244,101,101,,,1710256020,1390027205,1419250792,1697417099,39244,ERX9334780,ERS12088352,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93162,0.92801,0.15191,0.14943,0.67789,0.67951,0.47915,0.47762,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11038,ERR9787503,ERX9334779,ERS12088351,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 11,SAMEA14460874,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460874|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 11|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 11|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 11 p,Sample 11 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,TSCHOM6_1.fastq.gz TSCHOM6_2.fastq.gz,fastq fastq,6199081848.0,30688524.0,E MTAB 11776:TSCHOM6 ,0:101 1:101,A:1705859045;C:1387530558;G:1415224718;T:1690428701;N:38826,101,101,,,1705859045,1387530558,1415224718,1690428701,38826,ERX9334779,ERS12088351,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93583,0.93349,0.15923,0.15664,0.67976,0.67986,0.48632,0.48376,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11039,ERR9787502,ERX9334778,ERS12088350,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 10,SAMEA14460873,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460873|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 10|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 10|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 10 p,Sample 10 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,TSCHOM4_1.fastq.gz TSCHOM4_2.fastq.gz,fastq fastq,6287836204.0,31127902.0,E MTAB 11776:TSCHOM4 ,0:101 1:101,A:1673762523;C:1453880149;G:1493343671;T:1666809849;N:40012,101,101,,,1673762523,1453880149,1493343671,1666809849,40012,ERX9334778,ERS12088350,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.94269,0.9375,0.14166,0.13979,0.67476,0.67722,0.4927,0.49365,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
11040,ERR9787501,ERX9334777,ERS12088349,ERP137937,PRJEB53153,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E-MTAB-11776,Transcriptome Analysis,Transcriptome analysis of the heads of 5 dpf epdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae to provide insights into the neuropathological processes underlying the observed epileptic phenotype in sv2a /  zebrafish larvae.,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,,Protocols: 5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Sample 1,SAMEA14460872,"Laboratory for Molecular Biodiscovery, KU Leuven",ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12|External Id:SAMEA14460872|INSDC center alias:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC center name:Laboratory for Molecular Biodiscovery  KU Leuven|INSDC first public:2022 09 12T12:19:23Z|INSDC last update:2022 09 12T12:19:23Z|INSDC status:public|Submitter Id:E MTAB 11776:Sample 1|age:5|broker name:ArrayExpress|common name:zebrafish|developmental stage:larval stage|genotype:depdc5 /  x tsc2 / |individual:pool of 10 larvae|isolate:not applicable|organism part:head|sample name:E MTAB 11776:Sample 1|scientific name:Danio rerio|sex:non available|strain:AB,,,,,,,,,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,E MTAB 11776:Sample 1 p,Sample 1 p,RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,5 dpf zebrafish larvae were anesthetized and decapitated using a razor blade. 10 heads were pooled in quadruplicate per genotype. otal RNA was extracted using TRIzol reagent Invitrogen  followed by phenol chlorophorm extraction and isopropanol precipitation. post ethanol washes  the RNA pellet was air dried  dissolved in nuclease free water Fermentas. Illumina TruSeq Stranded mRNA Seq sample preparation kit was used to prepare the mRNA sequencing library according to the manufacturer guidelines.,Experimental Factor: genotype:depdc5 /  x tsc2 / ,RNA-Seq,TRANSCRIPTOMIC,PolyA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP137937,Illumina NovaSeq 6000 paired end sequencing; RNA seq of depdc5 /   tsc2 /   depdc5 /  x tsc2 /  and wildtype zebrafish larvae,ENA FIRST PUBLIC:2022 09 12|ENA LAST UPDATE:2022 09 12,2XHOM1_1.fastq.gz 2XHOM1_2.fastq.gz,fastq fastq,6232605768.0,30854484.0,E MTAB 11776:2XHOM1 ,0:101 1:101,A:1725401812;C:1384507160;G:1410306583;T:1712351429;N:38784,101,101,,,1725401812,1384507160,1410306583,1712351429,38784,ERX9334777,ERS12088349,ERA14756702,"Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive","Laboratory for Molecular Biodiscovery, KU Leuven|European Nucleotide Archive",2,0.93594,0.93262,0.15282,0.14977,0.67503,0.67373,0.49522,0.49759,101,101,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,trueseq,bulk,unknown,unknown,,Belgium,2022-09-12,Larval,Larval,Head,Nervous System
19221,ERR14935135,ERX14339377,ERS24360099,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H06,Humanized Plate 1   Well H06,SAMEA118225022,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 H06|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 H06|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 H06,webin reads Sample HUM1 H06,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 H06,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H06.R1.fastq.gz H06.R2.fastq.gz,fastq fastq,168135000.0,560450.0,webin reads Sample HUM1 H06,0:150 1:150,A:49336993;C:19637394;G:50002867;T:49156187;N:1559,150,150,,,49336993,19637394,50002867,49156187,1559,ERX14339377,ERS24360099,ERA33113052,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,mate1-mate2 similar by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19222,ERR14934924,ERX14339166,ERS24360038,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well C05,Humanized Plate 1   Well C05,SAMEA118224961,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 C05|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 C05|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 C05,webin reads Sample HUM1 C05,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 C05,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,C05.R1.fastq.gz C05.R2.fastq.gz,fastq fastq,406863000.0,1356210.0,webin reads Sample HUM1 C05,0:150 1:150,A:135043675;C:48707343;G:87607964;T:135501103;N:2915,150,150,,,135043675,48707343,87607964,135501103,2915,ERX14339166,ERS24360038,ERA33112290,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,mate1-mate2 similar by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19223,ERR14934974,ERX14339216,ERS24360047,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well D02,Humanized Plate 1   Well D02,SAMEA118224970,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 D02|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 D02|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 D02,webin reads Sample HUM1 D02,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 D02,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,D02.R1.fastq.gz D02.R2.fastq.gz,fastq fastq,231350700.0,771169.0,webin reads Sample HUM1 D02,0:150 1:150,A:61554211;C:27195025;G:82686912;T:59912853;N:1699,150,150,,,61554211,27195025,82686912,59912853,1699,ERX14339216,ERS24360047,ERA33112492,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19224,ERR14937148,ERX14341392,ERS24422818,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well G07,Humanized Plate 2   Well G07,SAMEA118242644,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 G07|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 G07|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 G07,webin reads Sample HUM2 G07,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 G07,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,G07.R1.fastq.gz G07.R2.fastq.gz,fastq fastq,1858827300.0,6196091.0,webin reads Sample HUM2 G07,0:150 1:150,A:377243729;C:275647713;G:834077378;T:371849924;N:8556,150,150,,,377243729,275647713,834077378,371849924,8556,ERX14341392,ERS24422818,ERA33115718,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19225,ERR14935143,ERX14339385,ERS24360101,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H08,Humanized Plate 1   Well H08,SAMEA118225024,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 H08|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 H08|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 H08,webin reads Sample HUM1 H08,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 H08,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H08.R1.fastq.gz H08.R2.fastq.gz,fastq fastq,104513100.0,348377.0,webin reads Sample HUM1 H08,0:150 1:150,A:24551652;C:12552824;G:43587381;T:23820238;N:1005,150,150,,,24551652,12552824,43587381,23820238,1005,ERX14339385,ERS24360101,ERA33113082,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19226,ERR14936904,ERX14341146,ERS24422763,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B12,Humanized Plate 2   Well B12,SAMEA118242589,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 B12|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 B12|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 B12,webin reads Sample HUM2 B12,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 B12,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B12.R1.fastq.gz B12.R2.fastq.gz,fastq fastq,14783024100.0,49276747.0,webin reads Sample HUM2 B12,0:150 1:150,A:4993941125;C:1900193626;G:3694935207;T:4193880937;N:73205,150,150,,,4993941125,1900193626,3694935207,4193880937,73205,ERX14341146,ERS24422763,ERA33115587,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19227,ERR14935120,ERX14339362,ERS24360094,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H01,Humanized Plate 1   Well H01,SAMEA118225017,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 H01|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 H01|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 H01,webin reads Sample HUM1 H01,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 H01,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H01.R1.fastq.gz H01.R2.fastq.gz,fastq fastq,214281900.0,714273.0,webin reads Sample HUM1 H01,0:150 1:150,A:63612930;C:24945238;G:64455038;T:61267490;N:1204,150,150,,,63612930,24945238,64455038,61267490,1204,ERX14339362,ERS24360094,ERA33112989,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19228,ERR14935021,ERX14339263,ERS24360064,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well E07,Humanized Plate 1   Well E07,SAMEA118224987,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 E07|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 E07|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 E07,webin reads Sample HUM1 E07,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 E07,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,E07.R1.fastq.gz E07.R2.fastq.gz,fastq fastq,274863600.0,916212.0,webin reads Sample HUM1 E07,0:150 1:150,A:89634361;C:31803602;G:65721376;T:87702420;N:1841,150,150,,,89634361,31803602,65721376,87702420,1841,ERX14339263,ERS24360064,ERA33112659,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,mate1-mate2 similar by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19229,ERR14950666,ERX14354790,ERS24422897,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well C09,Knockout Plate   Well C09,SAMEA118242723,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample KO C09|collection date:2022 05 13|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample KO C09|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample KO C09,webin reads Sample KO C09,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample KO C09,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,C09.R1.fastq.gz C09.R2.fastq.gz,fastq fastq,12910892700.0,43036309.0,webin reads Sample KO C09,0:150 1:150,A:4656205100;C:1791783755;G:2065221420;T:4397579948;N:102477,150,150,,,4656205100,1791783755,2065221420,4397579948,102477,ERX14354790,ERS24422897,ERA33121161,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19230,ERR14936878,ERX14341120,ERS24422755,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B04,Humanized Plate 2   Well B04,SAMEA118242581,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 B04|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 B04|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 B04,webin reads Sample HUM2 B04,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 B04,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B04.R1.fastq.gz B04.R2.fastq.gz,fastq fastq,2614344300.0,8714481.0,webin reads Sample HUM2 B04,0:150 1:150,A:495532634;C:388504084;G:1222436337;T:507858943;N:12302,150,150,,,495532634,388504084,1222436337,507858943,12302,ERX14341120,ERS24422755,ERA33115558,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19231,ERR14950561,ERX14354685,ERS24422871,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well A07,Knockout Plate   Well A07,SAMEA118242697,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample KO A07|collection date:2022 05 13|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample KO A07|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample KO A07,webin reads Sample KO A07,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample KO A07,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,A07.R1.fastq.gz A07.R2.fastq.gz,fastq fastq,3401128800.0,11337096.0,webin reads Sample KO A07,0:150 1:150,A:1234869505;C:459023584;G:579824655;T:1127383390;N:27666,150,150,,,1234869505,459023584,579824655,1127383390,27666,ERX14354685,ERS24422871,ERA33121056,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19232,ERR14936823,ERX14341065,ERS24422746,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well A07,Humanized Plate 2   Well A07,SAMEA118242572,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 A07|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 A07|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 A07,webin reads Sample HUM2 A07,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 A07,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,A07.R1.fastq.gz A07.R2.fastq.gz,fastq fastq,3778502100.0,12595007.0,webin reads Sample HUM2 A07,0:150 1:150,A:710336891;C:494217522;G:1880968771;T:692961837;N:17079,150,150,,,710336891,494217522,1880968771,692961837,17079,ERX14341065,ERS24422746,ERA33115511,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19233,ERR14937143,ERX14341387,ERS24422813,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well G02,Humanized Plate 2   Well G02,SAMEA118242639,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 G02|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 G02|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 G02,webin reads Sample HUM2 G02,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 G02,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,G02.R1.fastq.gz G02.R2.fastq.gz,fastq fastq,5962135800.0,19873786.0,webin reads Sample HUM2 G02,0:150 1:150,A:1745436521;C:821720129;G:1863789129;T:1531162608;N:27413,150,150,,,1745436521,821720129,1863789129,1531162608,27413,ERX14341387,ERS24422813,ERA33115710,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19234,ERR14934810,ERX14339052,ERS24360011,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well A02,Humanized Plate 1   Well A02,SAMEA118224934,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 A02|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 A02|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 A02,webin reads Sample HUM1 A02,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 A02,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,A02.R1.fastq.gz A02.R2.fastq.gz,fastq fastq,480559200.0,1601864.0,webin reads Sample HUM1 A02,0:150 1:150,A:163177108;C:53718756;G:98835089;T:164825485;N:2762,150,150,,,163177108,53718756,98835089,164825485,2762,ERX14339052,ERS24360011,ERA33111955,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,mate1-mate2 similar by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19235,ERR14934984,ERX14339226,ERS24360049,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well D04,Humanized Plate 1   Well D04,SAMEA118224972,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 D04|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 D04|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 D04,webin reads Sample HUM1 D04,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 D04,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,D04.R1.fastq.gz D04.R2.fastq.gz,fastq fastq,179225700.0,597419.0,webin reads Sample HUM1 D04,0:150 1:150,A:45457519;C:22876690;G:67395901;T:43493765;N:1825,150,150,,,45457519,22876690,67395901,43493765,1825,ERX14339226,ERS24360049,ERA33112537,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19236,ERR14934845,ERX14339087,ERS24360021,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well A12,Humanized Plate 1   Well A12,SAMEA118224944,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 A12|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 A12|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 A12,webin reads Sample HUM1 A12,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 A12,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,A12.R1.fastq.gz A12.R2.fastq.gz,fastq fastq,77425200.0,258084.0,webin reads Sample HUM1 A12,0:150 1:150,A:16644810;C:10391814;G:34720928;T:15667259;N:389,150,150,,,16644810,10391814,34720928,15667259,389,ERX14339087,ERS24360021,ERA33112104,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19237,ERR14934855,ERX14339097,ERS24360024,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B03,Humanized Plate 1   Well B03,SAMEA118224947,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 B03|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 B03|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 B03,webin reads Sample HUM1 B03,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 B03,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B03.R1.fastq.gz B03.R2.fastq.gz,fastq fastq,94155000.0,313850.0,webin reads Sample HUM1 B03,0:150 1:150,A:23101292;C:11479599;G:38484223;T:21089074;N:812,150,150,,,23101292,11479599,38484223,21089074,812,ERX14339097,ERS24360024,ERA33112137,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19238,ERR14943975,ERX14348127,ERS24422869,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well A05,Knockout Plate   Well A05,SAMEA118242695,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample KO A05|collection date:2022 05 13|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample KO A05|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample KO A05,webin reads Sample KO A05,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample KO A05,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,A05.R1.fastq.gz A05.R2.fastq.gz,fastq fastq,3911878200.0,13039594.0,webin reads Sample KO A05,0:150 1:150,A:1402938003;C:529582691;G:715316068;T:1264010327;N:31111,150,150,,,1402938003,529582691,715316068,1264010327,31111,ERX14348127,ERS24422869,ERA33119600,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19239,ERR14937117,ERX14341361,ERS24422810,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well F11,Humanized Plate 2   Well F11,SAMEA118242636,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 F11|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 F11|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 F11,webin reads Sample HUM2 F11,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 F11,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,F11.R1.fastq.gz F11.R2.fastq.gz,fastq fastq,3943764300.0,13145881.0,webin reads Sample HUM2 F11,0:150 1:150,A:1194917338;C:577472498;G:1192413538;T:978942667;N:18259,150,150,,,1194917338,577472498,1192413538,978942667,18259,ERX14341361,ERS24422810,ERA33115700,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19240,ERR14935149,ERX14339391,ERS24360104,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H11,Humanized Plate 1   Well H11,SAMEA118225027,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 H11|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 H11|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 H11,webin reads Sample HUM1 H11,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 H11,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H11.R1.fastq.gz H11.R2.fastq.gz,fastq fastq,29087400.0,96958.0,webin reads Sample HUM1 H11,0:150 1:150,A:5335277;C:3932942;G:14621885;T:5197119;N:177,150,150,,,5335277,3932942,14621885,5197119,177,ERX14339391,ERS24360104,ERA33113103,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19241,ERR14935025,ERX14339267,ERS24360065,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well E08,Humanized Plate 1   Well E08,SAMEA118224988,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 E08|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 E08|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 E08,webin reads Sample HUM1 E08,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 E08,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,E08.R1.fastq.gz E08.R2.fastq.gz,fastq fastq,220002300.0,733341.0,webin reads Sample HUM1 E08,0:150 1:150,A:62013327;C:25647839;G:72394925;T:59944865;N:1344,150,150,,,62013327,25647839,72394925,59944865,1344,ERX14339267,ERS24360065,ERA33112670,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19242,ERR14935108,ERX14339350,ERS24360090,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well G09,Humanized Plate 1   Well G09,SAMEA118225013,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 G09|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 G09|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 G09,webin reads Sample HUM1 G09,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 G09,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,G09.R1.fastq.gz G09.R2.fastq.gz,fastq fastq,55286400.0,184288.0,webin reads Sample HUM1 G09,0:150 1:150,A:9253015;C:6978214;G:29393822;T:9661042;N:307,150,150,,,9253015,6978214,29393822,9661042,307,ERX14339350,ERS24360090,ERA33112953,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19243,ERR14935106,ERX14339348,ERS24360089,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well G08,Humanized Plate 1   Well G08,SAMEA118225012,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 G08|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 G08|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 G08,webin reads Sample HUM1 G08,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 G08,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,G08.R1.fastq.gz G08.R2.fastq.gz,fastq fastq,90390000.0,301300.0,webin reads Sample HUM1 G08,0:150 1:150,A:14519869;C:11004100;G:49374862;T:15490478;N:691,150,150,,,14519869,11004100,49374862,15490478,691,ERX14339348,ERS24360089,ERA33112948,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19244,ERR14934877,ERX14339119,ERS24360032,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B11,Humanized Plate 1   Well B11,SAMEA118224955,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 B11|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 B11|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 B11,webin reads Sample HUM1 B11,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 B11,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B11.R1.fastq.gz B11.R2.fastq.gz,fastq fastq,99908700.0,333029.0,webin reads Sample HUM1 B11,0:150 1:150,A:22260827;C:11949991;G:42744522;T:22952623;N:737,150,150,,,22260827,11949991,42744522,22952623,737,ERX14339119,ERS24360032,ERA33112207,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19245,ERR14934885,ERX14339127,ERS24360034,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well C01,Humanized Plate 1   Well C01,SAMEA118224957,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 C01|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 C01|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 C01,webin reads Sample HUM1 C01,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 C01,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,C01.R1.fastq.gz C01.R2.fastq.gz,fastq fastq,101124300.0,337081.0,webin reads Sample HUM1 C01,0:150 1:150,A:21597244;C:13549354;G:45547786;T:20429406;N:510,150,150,,,21597244,13549354,45547786,20429406,510,ERX14339127,ERS24360034,ERA33112235,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19246,ERR14943984,ERX14348136,ERS24422880,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B04,Knockout Plate   Well B04,SAMEA118242706,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample KO B04|collection date:2022 05 13|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample KO B04|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample KO B04,webin reads Sample KO B04,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample KO B04,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B04.R1.fastq.gz B04.R2.fastq.gz,fastq fastq,561237900.0,1870793.0,webin reads Sample KO B04,0:150 1:150,A:192169170;C:77013107;G:120338699;T:171712356;N:4568,150,150,,,192169170,77013107,120338699,171712356,4568,ERX14348136,ERS24422880,ERA33119691,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19247,ERR14938992,ERX14343236,ERS24422834,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H11,Humanized Plate 2   Well H11,SAMEA118242660,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 H11|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 H11|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 H11,webin reads Sample HUM2 H11,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 H11,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H11.R1.fastq.gz H11.R2.fastq.gz,fastq fastq,1733814900.0,5779383.0,webin reads Sample HUM2 H11,0:150 1:150,A:378393702;C:284557462;G:721428373;T:349427441;N:7922,150,150,,,378393702,284557462,721428373,349427441,7922,ERX14343236,ERS24422834,ERA33115755,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19248,ERR14937159,ERX14341403,ERS24422829,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H06,Humanized Plate 2   Well H06,SAMEA118242655,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 H06|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 H06|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 H06,webin reads Sample HUM2 H06,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 H06,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H06.R1.fastq.gz H06.R2.fastq.gz,fastq fastq,8840167200.0,29467224.0,webin reads Sample HUM2 H06,0:150 1:150,A:3070163952;C:1202397032;G:1876790493;T:2690771671;N:44052,150,150,,,3070163952,1202397032,1876790493,2690771671,44052,ERX14341403,ERS24422829,ERA33115733,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,mate1-mate2 similar by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19249,ERR14934852,ERX14339094,ERS24360023,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B02,Humanized Plate 1   Well B02,SAMEA118224946,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 B02|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 B02|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 B02,webin reads Sample HUM1 B02,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 B02,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B02.R1.fastq.gz B02.R2.fastq.gz,fastq fastq,123106800.0,410356.0,webin reads Sample HUM1 B02,0:150 1:150,A:24870369;C:15859782;G:60046944;T:22329104;N:601,150,150,,,24870369,15859782,60046944,22329104,601,ERX14339094,ERS24360023,ERA33112126,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19250,ERR14936902,ERX14341144,ERS24422761,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B10,Humanized Plate 2   Well B10,SAMEA118242587,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 B10|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 B10|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 B10,webin reads Sample HUM2 B10,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 B10,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B10.R1.fastq.gz B10.R2.fastq.gz,fastq fastq,3818756100.0,12729187.0,webin reads Sample HUM2 B10,0:150 1:150,A:801009311;C:582803669;G:1691856038;T:743070146;N:16936,150,150,,,801009311,582803669,1691856038,743070146,16936,ERX14341144,ERS24422761,ERA33115582,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19251,ERR14935145,ERX14339387,ERS24360102,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well H09,Humanized Plate 1   Well H09,SAMEA118225025,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 H09|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 H09|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 H09,webin reads Sample HUM1 H09,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 H09,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,H09.R1.fastq.gz H09.R2.fastq.gz,fastq fastq,79435500.0,264785.0,webin reads Sample HUM1 H09,0:150 1:150,A:19325284;C:9616771;G:32084598;T:18408162;N:685,150,150,,,19325284,9616771,32084598,18408162,685,ERX14339387,ERS24360102,ERA33113089,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19252,ERR14935006,ERX14339248,ERS24360059,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well E02,Humanized Plate 1   Well E02,SAMEA118224982,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 E02|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 E02|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 E02,webin reads Sample HUM1 E02,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 E02,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,E02.R1.fastq.gz E02.R2.fastq.gz,fastq fastq,184473600.0,614912.0,webin reads Sample HUM1 E02,0:150 1:150,A:47275758;C:21941025;G:68635035;T:46620684;N:1098,150,150,,,47275758,21941025,68635035,46620684,1098,ERX14339248,ERS24360059,ERA33112606,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19253,ERR14937114,ERX14341358,ERS24422807,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well F08,Humanized Plate 2   Well F08,SAMEA118242633,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 F08|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 F08|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 F08,webin reads Sample HUM2 F08,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 F08,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,F08.R1.fastq.gz F08.R2.fastq.gz,fastq fastq,5604971400.0,18683238.0,webin reads Sample HUM2 F08,0:150 1:150,A:1272096391;C:927796029;G:2253030240;T:1152025287;N:23453,150,150,,,1272096391,927796029,2253030240,1152025287,23453,ERX14341358,ERS24422807,ERA33115697,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19254,ERR14935115,ERX14339357,ERS24360092,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well G11,Humanized Plate 1   Well G11,SAMEA118225015,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 G11|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 G11|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 G11,webin reads Sample HUM1 G11,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 G11,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,G11.R1.fastq.gz G11.R2.fastq.gz,fastq fastq,18225600.0,60752.0,webin reads Sample HUM1 G11,0:150 1:150,A:3396385;C:2248165;G:9171340;T:3409593;N:117,150,150,,,3396385,2248165,9171340,3409593,117,ERX14339357,ERS24360092,ERA33112973,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19255,ERR14950748,ERX14354872,ERS24422916,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well F01,Knockout Plate   Well F01,SAMEA118242742,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample KO F01|collection date:2022 05 13|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample KO F01|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample KO F01,webin reads Sample KO F01,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample KO F01,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,F01.R1.fastq.gz F01.R2.fastq.gz,fastq fastq,3161931900.0,10539773.0,webin reads Sample KO F01,0:150 1:150,A:1111325789;C:460593692;G:495389420;T:1094598021;N:24978,150,150,,,1111325789,460593692,495389420,1094598021,24978,ERX14354872,ERS24422916,ERA33121243,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,B,mate1 technical by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19256,ERR14934881,ERX14339123,ERS24360033,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well B12,Humanized Plate 1   Well B12,SAMEA118224956,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 B12|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 B12|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 B12,webin reads Sample HUM1 B12,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 B12,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,B12.R1.fastq.gz B12.R2.fastq.gz,fastq fastq,116537700.0,388459.0,webin reads Sample HUM1 B12,0:150 1:150,A:27658956;C:13844738;G:48483886;T:26549255;N:865,150,150,,,27658956,13844738,48483886,26549255,865,ERX14339123,ERS24360033,ERA33112224,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19257,ERR14934824,ERX14339066,ERS24360013,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well A04,Humanized Plate 1   Well A04,SAMEA118224936,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 A04|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 A04|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 A04,webin reads Sample HUM1 A04,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 A04,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,A04.R1.fastq.gz A04.R2.fastq.gz,fastq fastq,190861200.0,636204.0,webin reads Sample HUM1 A04,0:150 1:150,A:51866429;C:22469460;G:65825429;T:50698008;N:1874,150,150,,,51866429,22469460,65825429,50698008,1874,ERX14339066,ERS24360013,ERA33112023,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19258,ERR14934950,ERX14339192,ERS24360041,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well C08,Humanized Plate 1   Well C08,SAMEA118224964,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM1 C08|collection date:2022 11 14|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM1 C08|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM1 C08,webin reads Sample HUM1 C08,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM1 C08,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,C08.R1.fastq.gz C08.R2.fastq.gz,fastq fastq,347655600.0,1158852.0,webin reads Sample HUM1 C08,0:150 1:150,A:111273717;C:41410769;G:81188146;T:113779846;N:3122,150,150,,,111273717,41410769,81188146,113779846,3122,ERX14339192,ERS24360041,ERA33112408,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,B,B,mate1-mate2 similar by mapping diff,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System
19259,ERR14936959,ERX14341201,ERS24422772,ERP166068,PRJEB82358,Human gene duplications,53f6d331-4985-4b69-8ac3-a57d010118dd,Other,Duplicated genes expanded in the human lineage likely contributed to brain evolution  yet challenges exist in their discovery due to sequence assembly errors. We used a complete telomere to telomere genome sequence to identify 213 human specific gene families. From these  362 paralogs were found in all modern human genomes tested and brain transcriptomes  making them top candidates contributing to human universal brain features. Choosing a subset of paralogs  we used long read DNA sequencing of hundreds of modern humans to reveal previously hidden signatures of selection. To understand their roles in brain development  we generated zebrafish CRISPR “knockout” models of nine orthologs and introduced mRNA encoding paralogs  effectively “humanizing” larvae. Our findings implicate two new genes in possibly contributing to hallmark features of the human brain: GPR89B in dosage mediated brain expansion and FRMPD2B in altered synapse signaling. Our holistic approach provides new insights and a comprehensive resource for studying gene expansion drivers of human brain evolution.,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,,Single cell RNA sequencing of zebrafish heads from well C09,Humanized Plate 2   Well C09,SAMEA118242598,UNIVERSITY OF CALIFORNIA - DAVIS,ENA first public:2025 05 23|INSDC center name:UNIVERSITY OF CALIFORNIA   DAVIS|INSDC status:public|Submitter Id:Sample HUM2 C09|collection date:2022 12 21|common name:zebrafish|dev stage:72 hpf|geographic location country and/or sea:USA|sample name:Sample HUM2 C09|scientific name:Danio rerio,,,,,,,,,Raw reads: Sample HUM2 C09,webin reads Sample HUM2 C09,,unspecified,,ENA STATUS ID:4,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,cDNA,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,ERP166068,Raw reads: Sample HUM2 C09,ENA STATUS ID:4|ENA FIRST PUBLIC:2025 05 23|ENA LAST UPDATE:2025 05 23,C09.R1.fastq.gz C09.R2.fastq.gz,fastq fastq,3716150400.0,12387168.0,webin reads Sample HUM2 C09,0:150 1:150,A:950093356;C:589554852;G:1341746189;T:834739539;N:16464,150,150,,,950093356,589554852,1341746189,834739539,16464,ERX14341201,ERS24422772,ERA33115600,UNIVERSITY OF CALIFORNIA - DAVIS|European Nucleotide Archive,UNIVERSITY OF CALIFORNIA - DAVIS,,,,,,,,,,,,T,T,mates < 9% mapping rate,illumina,novaseq_era,unknown,poly_a,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2025-05-23,Larval,Larval,Head,Nervous System