rowid,run.accession,experiment.accession,sample.accession,study.accession,bioproject,study.title,study.alias,study.type,study.abstract,study.attributes,study.PMIDs,sample.description,sample.title,sample.alias,sample.centername,sample.attributes,GEOsample.title,GEOsample.dataprocessing,GEOsample.source,GEOsample.treatmentprotocol,GEOsample.extractprotocol,GEOsample.growthprotocol,GEOsample.characteristics,GEOsample.accession,experiment.title,experiment.alias,experiment.library_name,experiment.design_description,experiment.library_construction_protocol,experiment.attributes,experiment.library_strategy,experiment.library_source,experiment.library_selection,experiment.library_layout,experiment.platform,experiment.instrument_model,experiment.spot_descriptor,experiment.study_ref,run.title,run.attributes,run.filename,run.semantic_name,run.total_bases,run.total_spots,run.alias,run.read_lengths,run.base_counts,run.r1_length,run.r2_length,run.r3_length,run.r4_length,run.Acount,run.Ccount,run.Gcount,run.Tcount,run.Ncount,run.experiment,run.pool_member,submission.accession,submission.srasource,submission.bioprojectsource,seqdetective.n_mates,seqdetective.mapping_rate.mate1,seqdetective.mapping_rate.mate2,seqdetective.nofeature_rate.mate1,seqdetective.nofeature_rate.mate2,seqdetective.sparsity.mate1,seqdetective.sparsity.mate2,seqdetective.pos_strand_rate.mate1,seqdetective.pos_strand_rate.mate2,seqdetective.readlen.mate1,seqdetective.readlen.mate2,seqdetective.judgement.mate1,seqdetective.judgement.mate2,seqdetective.judgement.reason,platform_family,instrument_generation,read_bias,selection_class,prep_kit,sc_or_bulk,tech_class,technology,tech_variant,submission.bioprojectsource.country,earliest_date,devstage_curation,devstage_curation_coarse,tissue_curation,tissue_curation_coarse 31825,SRR28700412,SRX24268115,SRS21034395,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,PN 2,,isolate:PN2|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,PN 2,PN 2,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,PN_2_1.fq.gz PN_2_2.fq.gz,fastq fastq,6385048200.0,21283494.0,PN 2 1.fq.gz,0:150 1:150,A:1722127999;C:1463645587;G:1483173818;T:1716100796;N:0,150,150,,,1722127999,1463645587,1483173818,1716100796,0,SRX24268115,SRS21034395,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31826,SRR28700413,SRX24268114,SRS21034397,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,PN 1,,isolate:PN1|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,PN 1,PN 1,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,PN_1_1.fq.gz PN_1_2.fq.gz,fastq fastq,6692894100.0,22309647.0,PN 1 1.fq.gz,0:150 1:150,A:1827107021;C:1513034624;G:1533077624;T:1819674831;N:0,150,150,,,1827107021,1513034624,1533077624,1819674831,0,SRX24268114,SRS21034397,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31827,SRR28700414,SRX24268113,SRS21034396,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,EC 4,,isolate:EC4|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 4|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,EC 4,EC 4,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,EC_4_1.fq.gz EC_4_2.fq.gz,fastq fastq,6688857000.0,22296190.0,EC 4 1.fq.gz,0:150 1:150,A:1820989545;C:1516814697;G:1537970654;T:1813082104;N:0,150,150,,,1820989545,1516814697,1537970654,1813082104,0,SRX24268113,SRS21034396,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31828,SRR28700415,SRX24268112,SRS21034392,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,EC 3,,isolate:EC3|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,EC 3,EC 3,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,EC_3_1.fq.gz EC_3_2.fq.gz,fastq fastq,6696553800.0,22321846.0,EC 3 1.fq.gz,0:150 1:150,A:1821249100;C:1520587242;G:1541238550;T:1813478908;N:0,150,150,,,1821249100,1520587242,1541238550,1813478908,0,SRX24268112,SRS21034392,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31829,SRR28700416,SRX24268111,SRS21034391,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,EC 2,,isolate:EC2|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,EC 2,EC 2,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,EC_2_1.fq.gz EC_2_2.fq.gz,fastq fastq,6702179400.0,22340598.0,EC 2 1.fq.gz,0:150 1:150,A:1816692261;C:1527379142;G:1547365810;T:1810742187;N:0,150,150,,,1816692261,1527379142,1547365810,1810742187,0,SRX24268111,SRS21034391,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31830,SRR28700417,SRX24268110,SRS21034390,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,EC 1,,isolate:EC1|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,EC 1,EC 1,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,EC_1_1.fq.gz EC_1_2.fq.gz,fastq fastq,6686053500.0,22286845.0,EC 1 1.fq.gz,0:150 1:150,A:1812022780;C:1524359858;G:1544847441;T:1804823421;N:0,150,150,,,1812022780,1524359858,1544847441,1804823421,0,SRX24268110,SRS21034390,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31831,SRR28700418,SRX24268109,SRS21034388,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,Control 4,,isolate:con4|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 4|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,Control 4,Control 4,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,Control_4_1.fq.gz Control_4_2.fq.gz,fastq fastq,6669700500.0,22232335.0,Control 4 1.fq.gz,0:150 1:150,A:1804178265;C:1523547469;G:1543839484;T:1798135282;N:0,150,150,,,1804178265,1523547469,1543839484,1798135282,0,SRX24268109,SRS21034388,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31832,SRR28700419,SRX24268108,SRS21034387,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,Control 3,,isolate:con3|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,Control 3,Control 3,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,Control_3_1.fq.gz Control_3_2.fq.gz,fastq fastq,6683518800.0,22278396.0,Control 3 1.fq.gz,0:150 1:150,A:1808495506;C:1525725204;G:1545930043;T:1803368047;N:0,150,150,,,1808495506,1525725204,1545930043,1803368047,0,SRX24268108,SRS21034387,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31833,SRR28700420,SRX24268107,SRS21034386,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,PN 4,,isolate:PN4|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 4|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,PN 4,PN 4,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,PN_4_1.fq.gz PN_4_2.fq.gz,fastq fastq,6649316100.0,22164387.0,PN 4 1.fq.gz,0:150 1:150,A:1809816121;C:1508072480;G:1528272654;T:1803154845;N:0,150,150,,,1809816121,1508072480,1528272654,1803154845,0,SRX24268107,SRS21034386,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31834,SRR28700421,SRX24268106,SRS21034389,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,PN 3,,isolate:PN3|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,PN 3,PN 3,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,PN_3_1.fq.gz PN_3_2.fq.gz,fastq fastq,6616113900.0,22053713.0,PN 3 1.fq.gz,0:150 1:150,A:1802283686;C:1499008018;G:1519150002;T:1795672194;N:0,150,150,,,1802283686,1499008018,1519150002,1795672194,0,SRX24268106,SRS21034389,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31835,SRR28700422,SRX24268105,SRS21034385,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,Control 2,,isolate:con2|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,Control 2,Control 2,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,Control_2_1.fq.gz Control_2_2.fq.gz,fastq fastq,6701719200.0,22339064.0,Control 2 1.fq.gz,0:150 1:150,A:1812352260;C:1531672703;G:1551377072;T:1806317165;N:0,150,150,,,1812352260,1531672703,1551377072,1806317165,0,SRX24268105,SRS21034385,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 31836,SRR28700423,SRX24268104,SRS21034384,SRP501894,PRJNA1100624,Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis,PRJNA1100624,Other,Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.,,,,,Control 1,,isolate:con1|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish,Control 1,Control 1,Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP501894,,,Control_1_1.fq.gz Control_1_2.fq.gz,fastq fastq,6720214500.0,22400715.0,Control 1 1.fq.gz,0:150 1:150,A:1814883015;C:1537948710;G:1559376116;T:1808006659;N:0,150,150,,,1814883015,1537948710,1559376116,1808006659,0,SRX24268104,SRS21034384,,,"Xiangyang No.1 People's Hospital, Hubei University of Medicine",,,,,,,,,,,,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2024-04-15,Larval,Larval,Undetermined,Undetermined 55643,SRR10604044,SRX7283593,SRS5777402,SRP235014,PRJNA594101,Danio rerio Transcriptome,PRJNA594101,Other,Danio rerio Transcriptome post cGAS and STING knockout,,,,,stko2,,strain:not collected|isolate:sting knockout 2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebraish larvae,sting knockout 2,sting knockout 2,RNA seq,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP235014,,,stko2_1.fastq.gz stko2_2.fastq.gz,fastq fastq,10635609300.0,70904062.0,stko2 1.fastq.gz,0:150 1:150,A:2864931942;C:2450585568;G:2436540783;T:2882828480;N:722527,150,150,,,2864931942,2450585568,2436540783,2882828480,722527,SRX7283593,SRS5777402,SRA1007465,Shantou university medical college|Neuroscience Center,Shantou university medical college,1,0.93079,,0.07849,,0.70301,,0.47872,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2019-12-08,Larval,Larval,Undetermined,Undetermined 55644,SRR10604045,SRX7283592,SRS5777401,SRP235014,PRJNA594101,Danio rerio Transcriptome,PRJNA594101,Other,Danio rerio Transcriptome post cGAS and STING knockout,,,,,stko1,,strain:not collected|isolate:sting knockout 1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebraish larvae,sting knockout 1,sting knockout 1,RNA seq,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP235014,,,stko1_1.fastq.gz stko1_2.fastq.gz,fastq fastq,10453959000.0,69693060.0,stko1 1.fastq.gz,0:150 1:150,A:2823253748;C:2400078679;G:2379662427;T:2850274552;N:689594,150,150,,,2823253748,2400078679,2379662427,2850274552,689594,SRX7283592,SRS5777401,SRA1007465,Shantou university medical college|Neuroscience Center,Shantou university medical college,1,0.92736,,0.08475,,0.69822,,0.47233,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2019-12-08,Larval,Larval,Undetermined,Undetermined 55645,SRR10604046,SRX7283591,SRS5777400,SRP235014,PRJNA594101,Danio rerio Transcriptome,PRJNA594101,Other,Danio rerio Transcriptome post cGAS and STING knockout,,,,,cgko2,,strain:not collected|isolate:cgas knockout 2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebraish larvae,cgas knockout 2,cgas knockout 2,RNA seq,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP235014,,,cgko2_1.fastq.gz cgko2_2.fastq.gz,fastq fastq,10462236900.0,69748246.0,cgko2 1.fastq.gz,0:150 1:150,A:2836737922;C:2388112649;G:2370425883;T:2866326601;N:633845,150,150,,,2836737922,2388112649,2370425883,2866326601,633845,SRX7283591,SRS5777400,SRA1007465,Shantou university medical college|Neuroscience Center,Shantou university medical college,1,0.93603,,0.10606,,0.67765,,0.46153,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2019-12-08,Larval,Larval,Undetermined,Undetermined 55646,SRR10604047,SRX7283590,SRS5777399,SRP235014,PRJNA594101,Danio rerio Transcriptome,PRJNA594101,Other,Danio rerio Transcriptome post cGAS and STING knockout,,,,,cgko1,,strain:not collected|isolate:cgas knockout 1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebraish larvae,cgas knockout 1,cgas knockout 1,RNA seq,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP235014,,,cgko1_2.fastq.gz cgko1_1.fastq.gz,fastq fastq,10498495500.0,69989970.0,cgko1 1.fastq.gz,0:150 1:150,A:2845684832;C:2398817161;G:2379300746;T:2874108573;N:584188,150,150,,,2845684832,2398817161,2379300746,2874108573,584188,SRX7283590,SRS5777399,SRA1007465,Shantou university medical college|Neuroscience Center,Shantou university medical college,1,0.93684,,0.10589,,0.67933,,0.48363,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2019-12-08,Larval,Larval,Undetermined,Undetermined 55647,SRR10604048,SRX7283589,SRS5777398,SRP235014,PRJNA594101,Danio rerio Transcriptome,PRJNA594101,Other,Danio rerio Transcriptome post cGAS and STING knockout,,,,,wt2,,strain:not collected|isolate:normal 2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebraish larvae,wt normal 2,wt normal 2,RNA seq,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP235014,,,wt2_1.fastq.gz wt2_2.fastq.gz,fastq fastq,10660916400.0,71072776.0,wt2 1.fastq.gz,0:150 1:150,A:2906473511;C:2417423798;G:2405111864;T:2931146507;N:760720,150,150,,,2906473511,2417423798,2405111864,2931146507,760720,SRX7283589,SRS5777398,SRA1007465,Shantou university medical college|Neuroscience Center,Shantou university medical college,1,0.94167,,0.11781,,0.66831,,0.4757,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2019-12-08,Larval,Larval,Undetermined,Undetermined 55648,SRR10604049,SRX7283588,SRS5777397,SRP235014,PRJNA594101,Danio rerio Transcriptome,PRJNA594101,Other,Danio rerio Transcriptome post cGAS and STING knockout,,,,,wt1,,strain:not collected|isolate:normal 1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebraish larvae,wt nomal 1,wt nomal 1,RNA seq,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP235014,,,wt1_1.fastq.gz wt1_2.fastq.gz,fastq fastq,10599804000.0,70665360.0,wt1 1.fastq.gz,0:150 1:150,A:2896989124;C:2397285811;G:2382705623;T:2922067937;N:755505,150,150,,,2896989124,2397285811,2382705623,2922067937,755505,SRX7283588,SRS5777397,SRA1007465,Shantou university medical college|Neuroscience Center,Shantou university medical college,1,0.93947,,0.11723,,0.67203,,0.45826,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2019-12-08,Larval,Larval,Undetermined,Undetermined 65944,SRR15700565,SRX11996477,SRS10003992,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,R01,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:control|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,R01,R01,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,R01_1.fq.gz R01_2.fq.gz,fastq fastq,6781182900.0,45207886.0,R01 1.fq.gz,0:150 1:150,A:1988991157;C:1393829563;G:1402027963;T:1996312981;N:21236,150,150,,,1988991157,1393829563,1402027963,1996312981,21236,SRX11996477,SRS10003992,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91278,,0.20165,,0.71054,,0.54354,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65945,SRR15700566,SRX11996476,SRS10003991,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,EH3,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:AMI 40.0|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,EH3,EH3,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,EH3_1.fq.gz EH3_2.fq.gz,fastq fastq,6798939900.0,45326266.0,EH3 1.fq.gz,0:150 1:150,A:1958992563;C:1429773625;G:1441958341;T:1968192397;N:22974,150,150,,,1958992563,1429773625,1441958341,1968192397,22974,SRX11996476,SRS10003991,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91681,,0.18245,,0.7083,,0.5369,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65946,SRR15700567,SRX11996475,SRS10003990,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,EH2,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:AMI 40.0|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,EH2,EH2,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,EH2_1.fq.gz EH2_2.fq.gz,fastq fastq,6792825900.0,45285506.0,EH2 1.fq.gz,0:150 1:150,A:1958355652;C:1427389031;G:1440081079;T:1966978334;N:21804,150,150,,,1958355652,1427389031,1440081079,1966978334,21804,SRX11996475,SRS10003990,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91907,,0.17888,,0.70575,,0.54118,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65947,SRR15700568,SRX11996474,SRS10003989,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,EH1,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:AMI 40.0|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,EH1,EH1,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,EH1_1.fq.gz EH1_2.fq.gz,fastq fastq,6723154200.0,44821028.0,EH1 1.fq.gz,0:150 1:150,A:1939940725;C:1412087358;G:1424339686;T:1946764075;N:22356,150,150,,,1939940725,1412087358,1424339686,1946764075,22356,SRX11996474,SRS10003989,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91848,,0.1756,,0.71293,,0.54795,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65948,SRR15700569,SRX11996473,SRS10003988,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,EL3,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:AMI 2.5|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,EL3,EL3,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,EL3_1.fq.gz EL3_2.fq.gz,fastq fastq,6756746700.0,45044978.0,EL3 1.fq.gz,0:150 1:150,A:1958754520;C:1411572406;G:1418753117;T:1967647023;N:19634,150,150,,,1958754520,1411572406,1418753117,1967647023,19634,SRX11996473,SRS10003988,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91873,,0.18319,,0.71027,,0.55277,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65949,SRR15700570,SRX11996472,SRS10003987,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,EL2,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:AMI 2.5|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,EL2,EL2,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,EL2_1.fq.gz EL2_2.fq.gz,fastq fastq,6811200600.0,45408004.0,EL2 1.fq.gz,0:150 1:150,A:1961542081;C:1433135536;G:1446857456;T:1969644200;N:21327,150,150,,,1961542081,1433135536,1446857456,1969644200,21327,SRX11996472,SRS10003987,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91853,,0.17639,,0.71076,,0.54175,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65950,SRR15700571,SRX11996471,SRS10003986,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,EL1,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:AMI 2.5|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,EL1,EL1,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,EL1_1.fq.gz EL1_2.fq.gz,fastq fastq,6764302200.0,45095348.0,EL1 1.fq.gz,0:150 1:150,A:1943560425;C:1428175041;G:1441358638;T:1951185256;N:22840,150,150,,,1943560425,1428175041,1441358638,1951185256,22840,SRX11996471,SRS10003986,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91885,,0.17456,,0.71423,,0.53356,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65951,SRR15700572,SRX11996470,SRS10003985,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,E03,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:control|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,E03,E03,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,E03_1.fq.gz E03_2.fq.gz,fastq fastq,6762334500.0,45082230.0,E03 1.fq.gz,0:150 1:150,A:1941432663;C:1429093210;G:1444693949;T:1947091388;N:23290,150,150,,,1941432663,1429093210,1444693949,1947091388,23290,SRX11996470,SRS10003985,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91902,,0.17577,,0.71413,,0.54672,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65952,SRR15700573,SRX11996469,SRS10003984,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,RH3,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:AMI 40.0|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,RH3,RH3,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,RH3_1.fq.gz RH3_2.fq.gz,fastq fastq,6620159400.0,44134396.0,RH3 1.fq.gz,0:150 1:150,A:1906961918;C:1396128146;G:1402603611;T:1914452217;N:13508,150,150,,,1906961918,1396128146,1402603611,1914452217,13508,SRX11996469,SRS10003984,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91596,,0.18007,,0.70307,,0.53072,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65953,SRR15700574,SRX11996468,SRS10003983,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,RH2,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:AMI 40.0|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,RH2,RH2,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,RH2_1.fq.gz RH2_2.fq.gz,fastq fastq,6779957400.0,45199716.0,RH2 1.fq.gz,0:150 1:150,A:1943750299;C:1436936087;G:1447253724;T:1952003667;N:13623,150,150,,,1943750299,1436936087,1447253724,1952003667,13623,SRX11996468,SRS10003983,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91806,,0.17416,,0.70364,,0.53449,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65954,SRR15700575,SRX11996467,SRS10003982,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,RH1,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:AMI 40.0|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,RH1,RH1,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,RH1_1.fq.gz RH1_2.fq.gz,fastq fastq,6803711400.0,45358076.0,RH1 1.fq.gz,0:150 1:150,A:1919109429;C:1472916047;G:1485344758;T:1926327627;N:13539,150,150,,,1919109429,1472916047,1485344758,1926327627,13539,SRX11996467,SRS10003982,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.92595,,0.14064,,0.71392,,0.5508,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65955,SRR15700576,SRX11996466,SRS10003981,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,RL3,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:AMI 2.5|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,RL3,RL3,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,RL3_1.fq.gz RL3_2.fq.gz,fastq fastq,6775779300.0,45171862.0,RL3 1.fq.gz,0:150 1:150,A:1977555439;C:1404514814;G:1412262159;T:1981432811;N:14077,150,150,,,1977555439,1404514814,1412262159,1981432811,14077,SRX11996466,SRS10003981,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91883,,0.1833,,0.71638,,0.55343,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65956,SRR15700577,SRX11996465,SRS10003979,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,RL2,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:AMI 2.5|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,RL2,RL2,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,RL2_1.fq.gz RL2_2.fq.gz,fastq fastq,6716301900.0,44775346.0,RL2 1.fq.gz,0:150 1:150,A:1959165761;C:1392977724;G:1400724963;T:1963418595;N:14857,150,150,,,1959165761,1392977724,1400724963,1963418595,14857,SRX11996465,SRS10003979,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.92114,,0.18164,,0.7217,,0.55665,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65957,SRR15700578,SRX11996464,SRS10003980,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,RL1,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:AMI 2.5|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,RL1,RL1,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,RL1_1.fq.gz RL1_2.fq.gz,fastq fastq,6632905200.0,44219368.0,RL1 1.fq.gz,0:150 1:150,A:1930258593;C:1379056686;G:1391344096;T:1932223405;N:22420,150,150,,,1930258593,1379056686,1391344096,1932223405,22420,SRX11996464,SRS10003980,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91966,,0.18087,,0.72121,,0.5664,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65958,SRR15700579,SRX11996463,SRS10003978,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,R03,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:control|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,R03,R03,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,R03_1.fq.gz R03_2.fq.gz,fastq fastq,6574600200.0,43830668.0,R03 1.fq.gz,0:150 1:150,A:1940343461;C:1342685356;G:1350150434;T:1941399481;N:21468,150,150,,,1940343461,1342685356,1350150434,1941399481,21468,SRX11996463,SRS10003978,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91867,,0.19479,,0.72707,,0.57885,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65959,SRR15700580,SRX11996462,SRS10003977,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 21 DAY RECOVERY,,R02,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:control|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,R02,R02,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,R02_1.fq.gz R02_2.fq.gz,fastq fastq,6399007800.0,42660052.0,R02 1.fq.gz,0:150 1:150,A:1884110766;C:1308008993;G:1315054545;T:1891764364;N:69132,150,150,,,1884110766,1308008993,1315054545,1891764364,69132,SRX11996462,SRS10003977,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91477,,0.19859,,0.72417,,0.55394,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65960,SRR15700581,SRX11996461,SRS10003976,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,E02,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:control|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,E02,E02,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,E02_1.fq.gz E02_2.fq.gz,fastq fastq,6588207000.0,43921380.0,E02 1.fq.gz,0:150 1:150,A:1905685715;C:1379753621;G:1389708827;T:1913038146;N:20691,150,150,,,1905685715,1379753621,1389708827,1913038146,20691,SRX11996461,SRS10003976,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91596,,0.18027,,0.70903,,0.54349,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65961,SRR15700582,SRX11996460,SRS10003975,SRP335395,PRJNA759881,Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio,PRJNA759881,Other,Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.,,,END OF 7 DAY EXPOSURE,,E01,,strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:control|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: adult female brain,E01,E01,a standardized procedure at the Beijing Genome Institute,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP335395,,,E01_1.fq.gz E01_2.fq.gz,fastq fastq,6766213800.0,45108092.0,E01 1.fq.gz,0:150 1:150,A:1963125745;C:1410900205;G:1420069949;T:1972096961;N:20940,150,150,,,1963125745,1410900205,1420069949,1972096961,20940,SRX11996460,SRS10003975,SRA1288076,Jiangsu University|Institute of Environmental Health and Ecological S,Jiangsu University,1,0.91884,,0.18555,,0.71585,,0.5455,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-02,Adult,Adult,Brain,Nervous System 65984,SRR15859821,SRX12150937,SRS10130028,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at high concentration treatment,LNG H 1,AN,,strain:not collected2|isolate:whole fish13|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 1'|BioSampleModel:Model organism or animal,,,,,,,,,LNG H 1,BM,BM,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,50_1_R1.clean.fq.gz 50_1_R2.clean.fq.gz,fastq fastq,6850889266.0,22893917.0,50 1 R1.clean.fq.gz,0:149.83 1:149.42,A:1908972876;C:1556853849;G:1559240564;T:1825804841;N:17136,149,149,,,1908972876,1556853849,1559240564,1825804841,17136,SRX12150937,SRS10130028,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93957,0.92386,0.09467,0.08944,0.66582,0.67142,0.50349,0.499,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65985,SRR15859822,SRX12150936,SRS10130027,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at low concentration treatment,LNG L 4,M,,strain:not collected2|isolate:whole fish12|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 4'|BioSampleModel:Model organism or animal,,,,,,,,,LNG L 4,BL,BL,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,5_4_R1.clean.fq.gz 5_4_R2.clean.fq.gz,fastq fastq,6757301758.0,22579367.0,5 4 R1.clean.fq.gz,0:149.83 1:149.44,A:1886236851;C:1526321374;G:1529138861;T:1815587663;N:17009,149,149,,,1886236851,1526321374,1529138861,1815587663,17009,SRX12150936,SRS10130027,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93955,0.92322,0.09955,0.0937,0.66612,0.67056,0.4936,0.50296,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65986,SRR15859823,SRX12150935,SRS10130026,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at low concentration treatment,LNG L 3,AL,,strain:not collected2|isolate:whole fish11|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 3 prime|BioSampleModel:Model organism or animal,,,,,,,,,LNG L 3,BK,BK,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,5_3_R1.clean.fq.gz 5_3_R2.clean.fq.gz,fastq fastq,6942028867.0,23178890.0,5 3 R1.clean.fq.gz,0:149.82 1:149.68,A:1895507796;C:1573477638;G:1599422601;T:1873160988;N:459844,149,149,,,1895507796,1573477638,1599422601,1873160988,459844,SRX12150935,SRS10130026,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.92261,0.9213,0.10308,0.10394,0.67298,0.67677,0.50615,0.5026,150,145,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65987,SRR15859824,SRX12150934,SRS10130025,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Solvent control,SC2,AC,,strain:not collected2|isolate:whole fish2|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 2'|BioSampleModel:Model organism or animal,,,,,,,,,SC2,BB,BB,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,SC_2_R1.clean.fq.gz SC_2_R2.clean.fq.gz,fastq fastq,6847074418.0,22905359.0,SC 2 R1.clean.fq.gz,0:149.58 1:149.35,A:1835075664;C:1586631096;G:1607651961;T:1817247855;N:467842,149,149,,,1835075664,1586631096,1607651961,1817247855,467842,SRX12150934,SRS10130025,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93172,0.93195,0.07691,0.0771,0.67265,0.67665,0.48862,0.49579,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65988,SRR15859825,SRX12150933,SRS10130024,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Solvent control,SC1,AB,,strain:not collected2|isolate:whole fish1|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 1'|BioSampleModel:Model organism or animal,,,,,,,,,SC1,BA,BA,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,SC_1_R1.clean.fq.gz SC_1_R2.clean.fq.gz,fastq fastq,7101595814.0,23743270.0,SC 1 R1.clean.fq.gz,0:149.65 1:149.45,A:1888007422;C:1656304946;G:1683234514;T:1873563589;N:485343,149,149,,,1888007422,1656304946,1683234514,1873563589,485343,SRX12150933,SRS10130024,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93193,0.93408,0.08101,0.08156,0.6744,0.67785,0.49761,0.49038,150,149,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65989,SRR15859826,SRX12150932,SRS10130023,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at low concentration treatment,LNG L 2,AK,,strain:not collected2|isolate:whole fish10|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 2'|BioSampleModel:Model organism or animal,,,,,,,,,LNG L 2,BJ,BJ,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,5_2_R1.clean.fq.gz 5_2_R2.clean.fq.gz,fastq fastq,6978116268.0,23316955.0,5 2 R1.clean.fq.gz,0:149.72 1:149.55,A:1877413088;C:1609547451;G:1632121199;T:1858563731;N:470799,149,149,,,1877413088,1609547451,1632121199,1858563731,470799,SRX12150932,SRS10130023,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93086,0.93049,0.08702,0.08712,0.68357,0.68844,0.49793,0.48668,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65990,SRR15859827,SRX12150931,SRS10130022,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at low concentration treatment,LNG L 1,AJ,,strain:not collected2|isolate:whole fish9|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 1'|BioSampleModel:Model organism or animal,,,,,,,,,LNG L 1,BI,BI,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,5_1_R1.clean.fq.gz 5_1_R2.clean.fq.gz,fastq fastq,6306082896.0,21075245.0,5 1 R1.clean.fq.gz,0:149.70 1:149.52,A:1679788198;C:1469939151;G:1489873755;T:1666053801;N:427991,149,149,,,1679788198,1469939151,1489873755,1666053801,427991,SRX12150931,SRS10130022,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93145,0.93206,0.08123,0.08188,0.67951,0.68432,0.48499,0.48763,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65991,SRR15859828,SRX12150930,SRS10130021,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,dydrogesterone treatment,DDG 4,AI,,strain:not collected2|isolate:whole fish8|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 4'|BioSampleModel:Model organism or animal,,,,,,,,,DDG 4,BH,BH,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_4_R1.clean.fq.gz 100_4_R2.clean.fq.gz,fastq fastq,7014679884.0,23437449.0,100 4 R1.clean.fq.gz,0:149.72 1:149.57,A:1882114669;C:1625037935;G:1641102139;T:1865959279;N:465862,149,149,,,1882114669,1625037935,1641102139,1865959279,465862,SRX12150930,SRS10130021,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93236,0.93264,0.08797,0.08919,0.67574,0.67965,0.50279,0.495,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65992,SRR15859829,SRX12150929,SRS10130019,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,dydrogesterone treatment,DDG 3,AH,,strain:not collected2|isolate:whole fish7|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 3 prime|BioSampleModel:Model organism or animal,,,,,,,,,DDG 3,BG,BG,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_3_R1.clean.fq.gz 100_3_R2.clean.fq.gz,fastq fastq,7000790030.0,23371313.0,100 3 R1.clean.fq.gz,0:149.83 1:149.72,A:1906942833;C:1592634521;G:1609492258;T:1891245267;N:475151,149,149,,,1906942833,1592634521,1609492258,1891245267,475151,SRX12150929,SRS10130019,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.92801,0.92781,0.09747,0.09744,0.66517,0.66776,0.50246,0.49531,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65993,SRR15859830,SRX12150928,SRS10130020,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,dydrogesterone treatment,DDG 2,AG,,strain:not collected2|isolate:whole fish6|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 2'|BioSampleModel:Model organism or animal,,,,,,,,,DDG 2,BF,BF,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_2_R1.clean.fq.gz 100_2_R2.clean.fq.gz,fastq fastq,7075813310.0,23625836.0,100 2 R1.clean.fq.gz,0:149.82 1:149.68,A:1918796036;C:1619755625;G:1637664383;T:1899135516;N:461750,149,149,,,1918796036,1619755625,1637664383,1899135516,461750,SRX12150928,SRS10130020,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.92935,0.92868,0.08886,0.08912,0.65717,0.6621,0.4843,0.49415,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65994,SRR15859831,SRX12150927,SRS10130018,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,dydrogesterone treatment,DDG 1,AF,,strain:not collected2|isolate:whole fish5|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 1'|BioSampleModel:Model organism or animal,,,,,,,,,DDG 1,BE,BE,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_1_R1.clean.fq.gz 100_1_R2.clean.fq.gz,fastq fastq,6740898004.0,22511996.0,100 1 R1.clean.fq.gz,0:149.79 1:149.65,A:1828418830;C:1542362815;G:1564205385;T:1805464983;N:445991,149,149,,,1828418830,1542362815,1564205385,1805464983,445991,SRX12150927,SRS10130018,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.92893,0.92836,0.08577,0.08614,0.67639,0.68077,0.48573,0.49544,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65995,SRR15859832,SRX12150926,SRS10130016,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Solvent control,SC4,AE,,strain:not collected2|isolate:whole fish4|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 4'|BioSampleModel:Model organism or animal,,,,,,,,,SC4,BD,BD,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,SC_4_R1.clean.fq.gz SC_4_R2.clean.fq.gz,fastq fastq,6051468288.0,20209797.0,SC 4 R1.clean.fq.gz,0:149.80 1:149.63,A:1652651735;C:1373191643;G:1392749062;T:1632474997;N:400851,149,149,,,1652651735,1373191643,1392749062,1632474997,400851,SRX12150926,SRS10130016,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.92672,0.92501,0.09038,0.09121,0.66259,0.66565,0.49636,0.49698,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65996,SRR15859833,SRX12150925,SRS10130017,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at high concentration and dydrogesterone mixturestreatment,DDG+LNG H 1,AY,,strain:not collected2|isolate:whole fish24|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 4'|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG H 1,BX,BX,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_50_4_R1.clean.fq.gz 100_50_4_R2.clean.fq.gz,fastq fastq,6861007764.0,22938186.0,100 50 4 R1.clean.fq.gz,0:149.76 1:149.35,A:1881600852;C:1578987219;G:1582313999;T:1818088269;N:17425,149,149,,,1881600852,1578987219,1582313999,1818088269,17425,SRX12150925,SRS10130017,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93777,0.92424,0.09796,0.0931,0.66182,0.66746,0.49608,0.49787,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65997,SRR15859834,SRX12150924,SRS10130015,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at high concentration and dydrogesterone mixtures treatment,DDG+LNG H 1,AX,,strain:not collected2|isolate:whole fish23|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 3 prime|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG H 1,BW,BW,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_50_3_R1.clean.fq.gz 100_50_3_R2.clean.fq.gz,fastq fastq,6448167527.0,21546554.0,100 50 3 R1.clean.fq.gz,0:149.84 1:149.43,A:1776900923;C:1483436670;G:1478517308;T:1709296399;N:16227,149,149,,,1776900923,1483436670,1478517308,1709296399,16227,SRX12150924,SRS10130015,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.94114,0.92751,0.08812,0.0842,0.66557,0.67052,0.49525,0.49796,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65998,SRR15859835,SRX12150923,SRS10130014,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at high concentration and dydrogesterone mixtures treatment,DDG+LNG H 1,AW,,strain:not collected2|isolate:whole fish22|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 2'|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG H 1,BV,BV,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_50_2_R1.clean.fq.gz 100_50_2_R2.clean.fq.gz,fastq fastq,6097050612.0,20374795.0,100 50 2 R1.clean.fq.gz,0:149.83 1:149.42,A:1697937652;C:1387399999;G:1387536896;T:1624160680;N:15385,149,149,,,1697937652,1387399999,1387536896,1624160680,15385,SRX12150923,SRS10130014,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93921,0.92457,0.09156,0.08703,0.677,0.68268,0.51381,0.51338,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 65999,SRR15859836,SRX12150922,SRS10130013,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at high concentration and dydrogesterone mixtures treatment,DDG+LNG H 1,AV,,strain:not collected2|isolate:whole fish21|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 1'|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG H 1,BU,BU,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_50_1_R1.clean.fq.gz 100_50_1_R2.clean.fq.gz,fastq fastq,6200464490.0,20718210.0,100 50 1 R1.clean.fq.gz,0:149.84 1:149.44,A:1722773998;C:1411958803;G:1410364088;T:1655351787;N:15814,149,149,,,1722773998,1411958803,1410364088,1655351787,15814,SRX12150922,SRS10130013,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.94019,0.92317,0.09428,0.08799,0.66192,0.66813,0.50339,0.50384,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66000,SRR15859837,SRX12150921,SRS10130012,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Solvent control,SC3,AD,,strain:not collected2|isolate:whole fish3|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 3 prime|BioSampleModel:Model organism or animal,,,,,,,,,SC3,BC,BC,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,SC_3_R1.clean.fq.gz SC_3_R2.clean.fq.gz,fastq fastq,6744019219.0,22522868.0,SC 3 R1.clean.fq.gz,0:149.81 1:149.62,A:1832736009;C:1540439892;G:1560536404;T:1809859936;N:446978,149,149,,,1832736009,1540439892,1560536404,1809859936,446978,SRX12150921,SRS10130012,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.92908,0.92831,0.08407,0.08413,0.66748,0.67332,0.49151,0.50363,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66001,SRR15859838,SRX12150920,SRS10130011,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at low concentration and dydrogesterone mixtures treatment,DDG+LNG L 4,AU,,strain:not collected2|isolate:whole fish20|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 4'|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG L 4,BT,BT,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_5_4_R1.clean.fq.gz 100_5_4_R2.clean.fq.gz,fastq fastq,6698715338.0,22386760.0,100 5 4 R1.clean.fq.gz,0:149.82 1:149.41,A:1854944489;C:1532319316;G:1533554376;T:1777880466;N:16691,149,149,,,1854944489,1532319316,1533554376,1777880466,16691,SRX12150920,SRS10130011,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.93948,0.92423,0.09198,0.08752,0.66967,0.67513,0.49914,0.49616,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66002,SRR15859839,SRX12150919,SRS10130010,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at low concentration and dydrogesterone mixtures treatment,DDG+LNG L 3,AT,,strain:not collected2|isolate:whole fish19|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 3 prime|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG L 3,BS,BS,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_5_3_R1.clean.fq.gz 100_5_3_R2.clean.fq.gz,fastq fastq,6731263096.0,22494392.0,100 5 3 R1.clean.fq.gz,0:149.82 1:149.42,A:1853865687;C:1546635036;G:1549005691;T:1781740007;N:16675,149,149,,,1853865687,1546635036,1549005691,1781740007,16675,SRX12150919,SRS10130010,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.94161,0.92699,0.09368,0.08881,0.67146,0.67671,0.49075,0.4916,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66003,SRR15859840,SRX12150918,SRS10130009,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at low concentration and dydrogesterone mixtures treatment,DDG+LNG L 2,AS,,strain:not collected2|isolate:whole fish18|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 2'|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG L 2,BR,BR,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_5_2_R1.clean.fq.gz 100_5_2_R2.clean.fq.gz,fastq fastq,6856677730.0,22942302.0,100 5 2 R1.clean.fq.gz,0:149.63 1:149.23,A:1861833177;C:1593702006;G:1601437245;T:1799688067;N:17235,149,149,,,1861833177,1593702006,1601437245,1799688067,17235,SRX12150918,SRS10130009,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.94226,0.93085,0.08471,0.08039,0.67677,0.68191,0.48927,0.47969,150,148,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66004,SRR15859841,SRX12150917,SRS10130007,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,Levonorgestrel at low concentration and dydrogesterone mixtures treatment,DDG+LNG L 1,AR,,strain:not collected2|isolate:whole fish17|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 1'|BioSampleModel:Model organism or animal,,,,,,,,,DDG+LNG L 1,BQ,BQ,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,100_5_1_R1.clean.fq.gz 100_5_1_R2.clean.fq.gz,fastq fastq,6734596961.0,22519168.0,100 5 1 R1.clean.fq.gz,0:149.72 1:149.34,A:1835515639;C:1562058332;G:1561380426;T:1775625709;N:16855,149,149,,,1835515639,1562058332,1561380426,1775625709,16855,SRX12150917,SRS10130007,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.94108,0.92768,0.09123,0.08716,0.66967,0.6747,0.50584,0.50347,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66005,SRR15859842,SRX12150916,SRS10130006,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at high concentration treatment,LNG H 4,AQ,,strain:not collected2|isolate:whole fish16|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 4'|BioSampleModel:Model organism or animal,,,,,,,,,LNG H 4,BP,BP,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,50_4_R1.clean.fq.gz 50_4_R2.clean.fq.gz,fastq fastq,7033955938.0,23502039.0,50 4 R1.clean.fq.gz,0:149.84 1:149.46,A:1939982949;C:1612770444;G:1610988374;T:1870196531;N:17640,149,149,,,1939982949,1612770444,1610988374,1870196531,17640,SRX12150916,SRS10130006,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.94099,0.92749,0.09644,0.09215,0.67261,0.67838,0.49766,0.49584,150,149,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66006,SRR15859843,SRX12150915,SRS10130008,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at high concentration treatment,LNG H 3,AP,,strain:not collected2|isolate:whole fish15|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 3 prime|BioSampleModel:Model organism or animal,,,,,,,,,LNG H 3,BO,BO,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,50_3_R1.clean.fq.gz 50_3_R2.clean.fq.gz,fastq fastq,5819952570.0,19444342.0,50 3 R1.clean.fq.gz,0:149.86 1:149.46,A:1615559082;C:1328350353;G:1325535770;T:1550492661;N:14704,149,149,,,1615559082,1328350353,1325535770,1550492661,14704,SRX12150915,SRS10130008,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.9397,0.92495,0.09375,0.08838,0.669,0.67338,0.50535,0.5146,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66007,SRR15859844,SRX12150914,SRS10130005,SRP336743,PRJNA760976,Danio rerio strain:AB Transcriptome or Gene expression,PRJNA760976,Transcriptome Analysis,we investigated the effects of progestins on gonadal differentiation and sex determination in zebrafish,,,levonorgestrel treatment at high concentration treatment,LNG H 2,AO,,strain:not collected2|isolate:whole fish14|breed:not collected|cultivar:not applicable3|ecotype:not applicable4|age:4 weeks|dev stage:not applicable5|sex:missing|tissue:whole fish|replicate:'replicate = biological replicate 2'|BioSampleModel:Model organism or animal,,,,,,,,,LNG H 2,BN,BN,zebraifsh exposure,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP336743,,,50_2_R1.clean.fq.gz 50_2_R2.clean.fq.gz,fastq fastq,5888497480.0,19673249.0,50 2 R1.clean.fq.gz,0:149.84 1:149.47,A:1638307115;C:1337036459;G:1335389572;T:1577749137;N:15197,149,149,,,1638307115,1337036459,1335389572,1577749137,15197,SRX12150914,SRS10130005,SRA1291484,South China Normal University|School of Environment,South China Normal University,2,0.9395,0.92471,0.09382,0.08964,0.66785,0.67144,0.50388,0.5077,150,150,B,B,biological fallback assumption,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-09-12,Larval,Larval,Whole Organism,All anatomical structures 66966,SRR16965145,SRX13156590,SRS11088493,SRP346547,PRJNA780808,transcriptomics of carbendazim and enrofloxacin on zebrafish embryos,PRJNA780808,Other,reveal a interaction between ENF and CAR on metabolic regulation during development,,,,,1enf,,strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:7 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio :enrofloxacin group,enf 1,enf 1,96hpf zebrafish larvae enrofloxacin group,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP346547,,,enf_1.fq.gz enf_2.fq.gz,fastq fastq,6652389300.0,44349262.0,enf 1.fq.gz,0:150 1:150,A:1759651033;C:1563446116;G:1556912596;T:1772370048;N:9507,150,150,,,1759651033,1563446116,1556912596,1772370048,9507,SRX13156590,SRS11088493,SRA1329868,China Agricultural University|College of animal science and technology,China Agricultural University,1,0.94992,,0.06316,,0.66979,,0.48987,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-11-17,Larval,Larval,Undetermined,Undetermined 66971,SRR16965150,SRX13156585,SRS11088490,SRP346547,PRJNA780808,transcriptomics of carbendazim and enrofloxacin on zebrafish embryos,PRJNA780808,Other,reveal a interaction between ENF and CAR on metabolic regulation during development,,,,,2mix,,strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:11 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio :mixture group,mix 2,mix 2,96hpf zebrafish larvae mixture group,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP346547,,,car_2_2.fq.gz mix2_2_1.fq.gz,fastq fastq,6669719100.0,44464794.0,car 2 2.fq.gz,0:150 1:150,A:1815824677;C:1515086864;G:1506360115;T:1832433148;N:14296,150,150,,,1815824677,1515086864,1506360115,1832433148,14296,SRX13156585,SRS11088490,SRA1329868,China Agricultural University|College of animal science and technology,China Agricultural University,1,0.93884,,0.11657,,0.65527,,0.48114,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-11-17,Larval,Larval,Undetermined,Undetermined 66974,SRR16959538,SRX13151074,SRS11083380,SRP346418,PRJNA780940,transcriptomics of difenoconazole and dimethomorph on zebrafish embryos,PRJNA780940,Other,Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.,,,,,1+mix,,strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:10 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : mixture group,mix 1,mix 1,The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP346418,,,mix1_3_2.fq.gz mix1_1_1.fq.gz,fastq fastq,6639699600.0,44264664.0,mix1 1 1.fq.gz,0:150 1:150,A:1738687157;C:1575344731;G:1569683716;T:1755974708;N:9288,150,150,,,1738687157,1575344731,1569683716,1755974708,9288,SRX13151074,SRS11083380,SRA1330365,China Agricultural University|College of animal science and technology,China Agricultural University,1,0.95161,,0.05697,,0.6817,,0.48485,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-11-16,Larval,Larval,Undetermined,Undetermined 66981,SRR16959545,SRX13151067,SRS11083373,SRP346418,PRJNA780940,transcriptomics of difenoconazole and dimethomorph on zebrafish embryos,PRJNA780940,Other,Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.,,,,,2+mix,,strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:11 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : mixture group,mix 2,mix 2,The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP346418,,,mix1_2_1.fq.gz dim_3_2.fq.gz,fastq fastq,6589866900.0,43932446.0,dim 3 2.fq.gz,0:150 1:150,A:1782755416;C:1508342477;G:1501934674;T:1796820276;N:14057,150,150,,,1782755416,1508342477,1501934674,1796820276,14057,SRX13151067,SRS11083373,SRA1330365,China Agricultural University|College of animal science and technology,China Agricultural University,1,0.93861,,0.10685,,0.66393,,0.47194,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2021-11-16,Larval,Larval,Undetermined,Undetermined 67884,SRR17868935,SRX14028691,SRS11864778,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C4 1,,strain:danio rerio AgNPs4|breed:zebrafish10|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 4 1,AG 4 1,AG 4 1,treatment7,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C4-1_1.fq.gz C4-1_2.fq.gz,fastq fastq,6830916900.0,45539446.0,C4 1 1.fq.gz,0:150 1:150,A:2011586443;C:1405775454;G:1388504965;T:2024992696;N:57342,150,150,,,2011586443,1405775454,1388504965,2024992696,57342,SRX14028691,SRS11864778,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.92344,,0.21929,,0.71043,,0.46315,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67885,SRR17868936,SRX14028690,SRS11864777,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C2 3,,strain:danio rerio AgNPs2|breed:zebrafish9|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 2 3,AG 2 3,AG 2 3,treatment6,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C2-3_1.fq.gz C2-3_2.fq.gz,fastq fastq,6782959200.0,45219728.0,C2 3 1.fq.gz,0:150 1:150,A:1949560199;C:1443524899;G:1428814233;T:1960921903;N:137966,150,150,,,1949560199,1443524899,1428814233,1960921903,137966,SRX14028690,SRS11864777,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.93181,,0.17739,,0.6927,,0.50528,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67886,SRR17868937,SRX14028689,SRS11864776,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C2 2,,strain:danio rerio AgNPs2|breed:zebrafish8|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 2 2,AG 2 2,AG 2 2,treatment5,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C2-2_1.fq.gz C2-2_2.fq.gz,fastq fastq,6817863300.0,45452422.0,C2 2 1.fq.gz,0:150 1:150,A:1964890519;C:1446826412;G:1428708103;T:1977297439;N:140827,150,150,,,1964890519,1446826412,1428708103,1977297439,140827,SRX14028689,SRS11864776,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.93045,,0.17846,,0.69116,,0.48565,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67887,SRR17868938,SRX14028688,SRS11864774,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C2 1,,strain:danio rerio AgNPs2|breed:zebrafish7|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 2 1,AG 2 1,AG 2 1,treatment4,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C2-1_1.fq.gz C2-1_2.fq.gz,fastq fastq,6795911700.0,45306078.0,C2 1 1.fq.gz,0:150 1:150,A:1910936263;C:1486390531;G:1471463982;T:1927036309;N:84615,150,150,,,1910936263,1486390531,1471463982,1927036309,84615,SRX14028688,SRS11864774,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.93638,,0.14847,,0.6814,,0.46864,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67888,SRR17868939,SRX14028687,SRS11864775,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C1 3,,strain:danio rerio AgNPs1|breed:zebrafish6|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 1 3,AG 1 3,AG 1 3,treatment3,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C1-3_1.fq.gz C1-3_2.fq.gz,fastq fastq,6788960100.0,45259734.0,C1 3 1.fq.gz,0:150 1:150,A:1883226902;C:1511814926;G:1492397960;T:1901504019;N:16293,150,150,,,1883226902,1511814926,1492397960,1901504019,16293,SRX14028687,SRS11864775,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.94253,,0.12673,,0.67623,,0.49289,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67889,SRR17868940,SRX14028686,SRS11864773,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C1 2,,strain:danio rerio AgNPs1|breed:zebrafish5|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 1 2,AG 1 2,AG 1 2,treatment2,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C1-2_1.fq.gz C1-2_2.fq.gz,fastq fastq,6781043100.0,45206954.0,C1 2 1.fq.gz,0:150 1:150,A:1890710017;C:1500221789;G:1482973456;T:1907121929;N:15909,150,150,,,1890710017,1500221789,1482973456,1907121929,15909,SRX14028686,SRS11864773,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.93834,,0.13288,,0.67777,,0.49269,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67890,SRR17868941,SRX14028685,SRS11864772,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C1 1,,strain:danio rerio AgNPs1|breed:zebrafish4|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 1 1,AG 1 1,AG 1 1,treatment1,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C1-1_1.fq.gz C1-1_2.fq.gz,fastq fastq,6760511100.0,45070074.0,C1 1 1.fq.gz,0:150 1:150,A:1875451292;C:1504527737;G:1489983693;T:1890505493;N:42885,150,150,,,1875451292,1504527737,1489983693,1890505493,42885,SRX14028685,SRS11864772,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.94039,,0.1298,,0.68071,,0.49309,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67891,SRR17868942,SRX14028684,SRS11864771,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,WT3,,strain:danio rerio con3|breed:zebrafish3|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 0 3,WT 0 3,WT 0 3,control3,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,WT3_1.fq.gz WT3_2.fq.gz,fastq fastq,6735369300.0,44902462.0,WT3 1.fq.gz,0:150 1:150,A:1853105410;C:1513363689;G:1496503080;T:1872187115;N:210006,150,150,,,1853105410,1513363689,1496503080,1872187115,210006,SRX14028684,SRS11864771,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.94653,,0.11174,,0.69116,,0.49069,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67892,SRR17868943,SRX14028683,SRS11864768,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C4 3,,strain:danio rerio AgNPs4|breed:zebrafish12|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 4 3,AG 4 3,AG 4 3,treatment9,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C4-3_1.fq.gz C4-3_2.fq.gz,fastq fastq,7066801800.0,47112012.0,C4 3 1.fq.gz,0:150 1:150,A:2079705050;C:1456973666;G:1436564156;T:2093467396;N:91532,150,150,,,2079705050,1456973666,1436564156,2093467396,91532,SRX14028683,SRS11864768,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.92264,,0.21457,,0.70236,,0.52765,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67893,SRR17868944,SRX14028682,SRS11864769,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,C4 2,,strain:danio rerio AgNPs4|breed:zebrafish11|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 4 2,AG 4 2,AG 4 2,treatment8,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,C4-2_1.fq.gz C4-2_2.fq.gz,fastq fastq,6813742200.0,45424948.0,C4 2 1.fq.gz,0:150 1:150,A:1969847243;C:1438590202;G:1418612399;T:1986677730;N:14626,150,150,,,1969847243,1438590202,1418612399,1986677730,14626,SRX14028682,SRS11864769,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.92909,,0.18109,,0.69029,,0.50538,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67894,SRR17868945,SRX14028681,SRS11864770,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,WT2,,strain:danio rerio con2|breed:zebrafish2|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 0 2,WT 0 2,WT 0 2,control2,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,WT2_1.fq.gz WT2_2.fq.gz,fastq fastq,6760866900.0,45072446.0,WT2 1.fq.gz,0:150 1:150,A:1893259201;C:1485992528;G:1471666738;T:1909709705;N:238728,150,150,,,1893259201,1485992528,1471666738,1909709705,238728,SRX14028681,SRS11864770,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.94132,,0.13956,,0.68596,,0.48309,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 67895,SRR17868946,SRX14028680,SRS11864767,SRP358022,PRJNA793391,Effects of acute exposure to nano silver on zebrafish larvae,PRJNA793391,Other,Sliver nanoparticles AgNPs are widely used for industry agriculture and medicals which potentially result in adverse effects for human health and aquatic environment. In this present study we investigated the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.,,,,,WT1,,strain:danio rerio con1|breed:zebrafish1|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal,,,,,,,,,DANIO RERIO 0 1,WT 0 1,WT 0 1,control1,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP358022,,,WT1_1.fq.gz WT1_2.fq.gz,fastq fastq,7003449300.0,46689662.0,WT1 1.fq.gz,0:150 1:150,A:1946491315;C:1554368011;G:1539879203;T:1962458586;N:252185,150,150,,,1946491315,1554368011,1539879203,1962458586,252185,SRX14028680,SRS11864767,SRA1350965,Center for Neuroscience|Shantou university,Center for Neuroscience,1,0.94236,,0.12627,,0.68369,,0.49408,,150,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,United States,2022-02-03,Larval,Larval,Whole Organism,All anatomical structures 74160,SRR23576624,SRX19463433,SRS16856056,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T1B,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert no Cre R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T1B,T1B,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T1B_1.fq.gz T1B_2.fq.gz,fastq fastq,12301883400.0,123018834.0,T1B 1.fq.gz,0:100 1:100,A:3241228917;C:2853095411;G:2904960052;T:3302599020;N:0,100,100,,,3241228917,2853095411,2904960052,3302599020,0,SRX19463433,SRS16856056,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95272,,0.09396,,0.68469,,0.54489,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74161,SRR23576625,SRX19463432,SRS16856055,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M9,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M9,M9,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M9_1.fq.gz M9_2.fq.gz,fastq fastq,10791781600.0,107917816.0,M9 1.fq.gz,0:100 1:100,A:2848108353;C:2487301410;G:2561260439;T:2895111398;N:0,100,100,,,2848108353,2487301410,2561260439,2895111398,0,SRX19463432,SRS16856055,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95252,,0.05974,,0.79184,,0.6274,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74162,SRR23576626,SRX19463431,SRS16856054,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M8,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M8,M8,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M8_1.fq.gz M8_2.fq.gz,fastq fastq,10803624400.0,108036244.0,M8 1.fq.gz,0:100 1:100,A:2826927335;C:2516499907;G:2585204327;T:2874992831;N:0,100,100,,,2826927335,2516499907,2585204327,2874992831,0,SRX19463431,SRS16856054,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95494,,0.06268,,0.79139,,0.60873,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74163,SRR23576627,SRX19463430,SRS16856053,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M7,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M7,M7,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M7_1.fq.gz M7_2.fq.gz,fastq fastq,10794944600.0,107949446.0,M7 1.fq.gz,0:100 1:100,A:2822800001;C:2515936087;G:2583221720;T:2872986792;N:0,100,100,,,2822800001,2515936087,2583221720,2872986792,0,SRX19463430,SRS16856053,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95392,,0.0552,,0.78967,,0.61766,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74164,SRR23576628,SRX19463429,SRS16856052,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M6,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M6,M6,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M6_1.fq.gz M6_2.fq.gz,fastq fastq,10806717200.0,108067172.0,M6 1.fq.gz,0:100 1:100,A:2872422644;C:2476696362;G:2537205428;T:2920392766;N:0,100,100,,,2872422644,2476696362,2537205428,2920392766,0,SRX19463429,SRS16856052,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95383,,0.06563,,0.79293,,0.63948,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74165,SRR23576629,SRX19463428,SRS16856051,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M5,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M5,M5,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M5_1.fq.gz M5_2.fq.gz,fastq fastq,10553024000.0,105530240.0,M5 1.fq.gz,0:100 1:100,A:2756587901;C:2467885042;G:2531072385;T:2797478672;N:0,100,100,,,2756587901,2467885042,2531072385,2797478672,0,SRX19463428,SRS16856051,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95761,,0.05754,,0.79435,,0.61791,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74166,SRR23576630,SRX19463427,SRS16856048,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M4,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M4,M4,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M4_1.fq.gz M4_2.fq.gz,fastq fastq,10821109400.0,108211094.0,M4 1.fq.gz,0:100 1:100,A:2853720356;C:2500021520;G:2567460910;T:2899906614;N:0,100,100,,,2853720356,2500021520,2567460910,2899906614,0,SRX19463427,SRS16856048,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95171,,0.0636,,0.78644,,0.61061,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74167,SRR23576631,SRX19463426,SRS16856050,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K9,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow WT R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K9,K9,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k9_1.fq.gz k9_2.fq.gz,fastq fastq,12170484800.0,121704848.0,k9 1.fq.gz,0:100 1:100,A:3429398396;C:2639165188;G:2664600070;T:3437321146;N:0,100,100,,,3429398396,2639165188,2664600070,3437321146,0,SRX19463426,SRS16856050,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.93913,,0.13619,,0.76623,,0.63929,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74168,SRR23576632,SRX19463425,SRS16856047,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K8,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow WT R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K8,K8,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k8_1.fq.gz k8_2.fq.gz,fastq fastq,12160185000.0,121601850.0,k8 1.fq.gz,0:100 1:100,A:3416677165;C:2642321577;G:2671959016;T:3429227242;N:0,100,100,,,3416677165,2642321577,2671959016,3429227242,0,SRX19463425,SRS16856047,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94207,,0.13408,,0.76211,,0.63866,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74169,SRR23576633,SRX19463424,SRS16856049,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K7,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow WT R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K7,K7,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k7_1.fq.gz k7_2.fq.gz,fastq fastq,12148090800.0,121480908.0,k7 1.fq.gz,0:100 1:100,A:3393484862;C:2656728106;G:2695881495;T:3401996337;N:0,100,100,,,3393484862,2656728106,2695881495,3401996337,0,SRX19463424,SRS16856049,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.93783,,0.12581,,0.76205,,0.61561,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74170,SRR23576634,SRX19463423,SRS16856046,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K6,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow tert Cre R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K6,K6,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k6_1.fq.gz k6_2.fq.gz,fastq fastq,12173062600.0,121730626.0,k6 1.fq.gz,0:100 1:100,A:3357618903;C:2705746086;G:2734807941;T:3374889670;N:0,100,100,,,3357618903,2705746086,2734807941,3374889670,0,SRX19463423,SRS16856046,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94651,,0.13977,,0.76575,,0.62959,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74171,SRR23576635,SRX19463422,SRS16856045,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K5,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow tert Cre R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K5,K5,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k5_1.fq.gz k5_2.fq.gz,fastq fastq,12151346800.0,121513468.0,k5 1.fq.gz,0:100 1:100,A:3323730498;C:2725613099;G:2760112468;T:3341890735;N:0,100,100,,,3323730498,2725613099,2760112468,3341890735,0,SRX19463422,SRS16856045,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94297,,0.12142,,0.75836,,0.6001,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74172,SRR23576636,SRX19463421,SRS16856044,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K4,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow tert Cre R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K4,K4,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k4_1.fq.gz k4_2.fq.gz,fastq fastq,12130512600.0,121305126.0,k4 1.fq.gz,0:100 1:100,A:3347896596;C:2682409134;G:2729255490;T:3370951380;N:0,100,100,,,3347896596,2682409134,2729255490,3370951380,0,SRX19463421,SRS16856044,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94729,,0.12594,,0.75684,,0.53755,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74173,SRR23576637,SRX19463420,SRS16856043,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K3,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow no Cre R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K3,K3,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k3_1.fq.gz k3_2.fq.gz,fastq fastq,12414982200.0,124149822.0,k3 1.fq.gz,0:100 1:100,A:3396256131;C:2779475706;G:2819830912;T:3419419451;N:0,100,100,,,3396256131,2779475706,2819830912,3419419451,0,SRX19463420,SRS16856043,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94186,,0.13004,,0.7613,,0.53529,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74174,SRR23576638,SRX19463419,SRS16856040,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,M3,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male gut,M3,M3,RNA Seq of Danio rerio : adult male gut,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,M3_1.fq.gz M3_2.fq.gz,fastq fastq,10811204400.0,108112044.0,M3 1.fq.gz,0:100 1:100,A:2826338851;C:2514522241;G:2594843889;T:2875499419;N:0,100,100,,,2826338851,2514522241,2594843889,2875499419,0,SRX19463419,SRS16856040,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.95049,,0.05611,,0.79127,,0.60997,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gut,Digestive System 74175,SRR23576639,SRX19463418,SRS16856041,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K2,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow no Cre R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K2,K2,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k2_1.fq.gz k2_2.fq.gz,fastq fastq,12163413800.0,121634138.0,k2 1.fq.gz,0:100 1:100,A:3349566787;C:2697789330;G:2746344614;T:3369713069;N:0,100,100,,,3349566787,2697789330,2746344614,3369713069,0,SRX19463418,SRS16856041,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.93698,,0.12494,,0.73933,,0.59199,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74176,SRR23576640,SRX19463417,SRS16856042,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,K1,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow no Cre R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male kidney marrow,K1,K1,RNA Seq of Danio rerio : adult male kidney marrow,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,k1_1.fq.gz k1_2.fq.gz,fastq fastq,12163054400.0,121630544.0,k1 1.fq.gz,0:100 1:100,A:3337026687;C:2722574700;G:2757511786;T:3345941227;N:0,100,100,,,3337026687,2722574700,2757511786,3345941227,0,SRX19463417,SRS16856042,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94273,,0.11801,,0.75258,,0.57192,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Kidney,Renal System 74177,SRR23576641,SRX19463416,SRS16856039,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T9,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T9,T9,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T9_1.fq.gz T9_2.fq.gz,fastq fastq,12386772800.0,123867728.0,T9 1.fq.gz,0:100 1:100,A:3400599530;C:2772066139;G:2813890387;T:3400216744;N:0,100,100,,,3400599530,2772066139,2813890387,3400216744,0,SRX19463416,SRS16856039,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.93775,,0.12024,,0.63838,,0.49765,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74178,SRR23576642,SRX19463415,SRS16856037,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T8,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T8,T8,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T8_1.fq.gz T8_2.fq.gz,fastq fastq,12176715600.0,121767156.0,T8 1.fq.gz,0:100 1:100,A:3287270041;C:2775700062;G:2808469679;T:3305275818;N:0,100,100,,,3287270041,2775700062,2808469679,3305275818,0,SRX19463415,SRS16856037,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94261,,0.12625,,0.63838,,0.49901,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74179,SRR23576643,SRX19463414,SRS16856038,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T7,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T7,T7,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T7_1.fq.gz T7_2.fq.gz,fastq fastq,12172655600.0,121726556.0,T7 1.fq.gz,0:100 1:100,A:3248593263;C:2809119242;G:2855399333;T:3259543762;N:0,100,100,,,3248593263,2809119242,2855399333,3259543762,0,SRX19463414,SRS16856038,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94602,,0.10229,,0.63603,,0.48805,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74180,SRR23576644,SRX19463413,SRS16856036,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T6,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert Cre R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T6,T6,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T6_1.fq.gz T6_2.fq.gz,fastq fastq,12378860000.0,123788600.0,T6 1.fq.gz,0:100 1:100,A:3314969512;C:2848487369;G:2903637904;T:3311765215;N:0,100,100,,,3314969512,2848487369,2903637904,3311765215,0,SRX19463413,SRS16856036,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94452,,0.10777,,0.62422,,0.49742,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74181,SRR23576645,SRX19463412,SRS16856034,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T5,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert Cre R2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T5,T5,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T5_1.fq.gz T5_2.fq.gz,fastq fastq,12128636200.0,121286362.0,T5 1.fq.gz,0:100 1:100,A:3365971947;C:2671909728;G:2726788212;T:3363966313;N:0,100,100,,,3365971947,2671909728,2726788212,3363966313,0,SRX19463412,SRS16856034,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.93852,,0.14946,,0.63747,,0.52613,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74182,SRR23576646,SRX19463411,SRS16856032,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T4,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert Cre R1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T4,T4,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T4_1.fq.gz T4_2.fq.gz,fastq fastq,12162901400.0,121629014.0,T4 1.fq.gz,0:100 1:100,A:3278648055;C:2767244505;G:2825703918;T:3291304922;N:0,100,100,,,3278648055,2767244505,2825703918,3291304922,0,SRX19463411,SRS16856032,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.94511,,0.11642,,0.63258,,0.4913,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System 74183,SRR23576647,SRX19463410,SRS16856035,SRP423783,PRJNA937311,Telomere elongation in the gut extends systemic healthspan of zebrafish,PRJNA937311,Other,Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However whether telomere dependent aging of an individual organ the gut causes systemic aging remains unknown. Here we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively we show that gut specific telomerase expression extends lifespan of tert / by 40 % while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.,,,,,T3,,strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert no Cre R3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio : adult male testis,T3,T3,RNA Seq of Danio rerio : adult male testis,,,RNA-Seq,TRANSCRIPTOMIC,Oligo-dT,PAIRED,BGISEQ,BGISEQ-500,,SRP423783,,,T3_1.fq.gz T3_2.fq.gz,fastq fastq,12163321600.0,121633216.0,T3 1.fq.gz,0:100 1:100,A:3285334843;C:2767357208;G:2816394061;T:3294235488;N:0,100,100,,,3285334843,2767357208,2816394061,3294235488,0,SRX19463410,SRS16856035,SRA1593824,Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center Miguel Godinho Ferreira,1,0.9415,,0.11969,,0.62666,,0.50292,,100,,B,,usable mapping rate,bgi,bgi,unknown,poly_a,unknown,bulk,unknown,unknown,,China,2023-02-21,Adult,Adult,Gonad,Reproductive System