rowid,run.accession,experiment.accession,sample.accession,study.accession,bioproject,study.title,study.alias,study.type,study.abstract,study.attributes,study.PMIDs,sample.description,sample.title,sample.alias,sample.centername,sample.attributes,GEOsample.title,GEOsample.dataprocessing,GEOsample.source,GEOsample.treatmentprotocol,GEOsample.extractprotocol,GEOsample.growthprotocol,GEOsample.characteristics,GEOsample.accession,experiment.title,experiment.alias,experiment.library_name,experiment.design_description,experiment.library_construction_protocol,experiment.attributes,experiment.library_strategy,experiment.library_source,experiment.library_selection,experiment.library_layout,experiment.platform,experiment.instrument_model,experiment.spot_descriptor,experiment.study_ref,run.title,run.attributes,run.filename,run.semantic_name,run.total_bases,run.total_spots,run.alias,run.read_lengths,run.base_counts,run.r1_length,run.r2_length,run.r3_length,run.r4_length,run.Acount,run.Ccount,run.Gcount,run.Tcount,run.Ncount,run.experiment,run.pool_member,submission.accession,submission.srasource,submission.bioprojectsource,seqdetective.n_mates,seqdetective.mapping_rate.mate1,seqdetective.mapping_rate.mate2,seqdetective.nofeature_rate.mate1,seqdetective.nofeature_rate.mate2,seqdetective.sparsity.mate1,seqdetective.sparsity.mate2,seqdetective.pos_strand_rate.mate1,seqdetective.pos_strand_rate.mate2,seqdetective.readlen.mate1,seqdetective.readlen.mate2,seqdetective.judgement.mate1,seqdetective.judgement.mate2,seqdetective.judgement.reason,platform_family,instrument_generation,read_bias,selection_class,prep_kit,sc_or_bulk,tech_class,technology,tech_variant,submission.bioprojectsource.country,earliest_date,devstage_curation,devstage_curation_coarse,tissue_curation,tissue_curation_coarse
30066,SRR27676305,SRX23343658,SRS20205511,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,smart seq of setdb1b mt 2,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:96hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 2|id</u><u>:9</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,smart seq of setdb1b mt 2,smart seq of setdb1b mt 2,smart seq of setdb1b mt 2,smart seq of setdb1b mt of replicate 2,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,smart-seq of setdb1b mt_2_R2.fastq.gz.gz smart-seq of setdb1b mt_2_R1.fastq.gz.gz,fastq fastq,11957458200.0,39858194.0,smart seq of setdb1b mt 2 R1.fastq.gz.gz,0:150 1:150,A:3692371435;C:1893324720;G:2810967928;T:3560751613;N:42504,150,150,,,3692371435,1893324720,2810967928,3560751613,42504,SRX23343658,SRS20205511,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.76332,0.82639,0.22191,0.23939,0.87093,0.87117,0.59757,0.60008,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30067,SRR27676306,SRX23343657,SRS20205510,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,smart seq of setdb1b mt 1,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:96hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 1|id</u><u>:8</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,smart seq of setdb1b mt 1,smart seq of setdb1b mt 1,smart seq of setdb1b mt 1,smart seq of setdb1b mt of replicate 1,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,smart-seq of setdb1b mt_1_R1.fastq.gz.gz smart-seq of setdb1b mt_1_R2.fastq.gz.gz,fastq fastq,9537788700.0,31792629.0,smart seq of setdb1b mt 1 R1.fastq.gz.gz,0:150 1:150,A:3044433376;C:1450924984;G:2142347814;T:2900047705;N:34821,150,150,,,3044433376,1450924984,2142347814,2900047705,34821,SRX23343657,SRS20205510,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.74808,0.79354,0.21148,0.22263,0.87405,0.87545,0.58431,0.58836,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30068,SRR27676307,SRX23343656,SRS20205509,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,smart seq of setdb1b control 2,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:96hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 2|id</u><u>:7</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,smart seq of setdb1b control 2,smart seq of setdb1b control 2,smart seq of setdb1b control 2,smart seq of setdb1b control of replicate 2,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,smart-seq of setdb1b control_2_R1.fastq.gz.gz smart-seq of setdb1b control_2_R2.fastq.gz.gz,fastq fastq,7963596600.0,26545322.0,smart seq of setdb1b control 2 R1.fastq.gz.gz,0:150 1:150,A:2522387513;C:1217203824;G:1776725064;T:2447251088;N:29111,150,150,,,2522387513,1217203824,1776725064,2447251088,29111,SRX23343656,SRS20205509,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.77121,0.80578,0.22631,0.23757,0.85953,0.86298,0.58219,0.58387,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30069,SRR27676308,SRX23343655,SRS20205508,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,smart seq of setdb1b control 1,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:96hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 1|id</u><u>:6</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,smart seq of setdb1b control 1,smart seq of setdb1b control 1,smart seq of setdb1b control 1,smart seq of setdb1b control of replicate 1,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,smart-seq of setdb1b control_1_R2.fastq.gz.gz smart-seq of setdb1b control_1_R1.fastq.gz.gz,fastq fastq,11867370900.0,39557903.0,smart seq of setdb1b control 1 R1.fastq.gz.gz,0:150 1:150,A:3969636478;C:1678555005;G:2520767064;T:3698368678;N:43675,150,150,,,3969636478,1678555005,2520767064,3698368678,43675,SRX23343655,SRS20205508,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.73517,0.73836,0.23036,0.23129,0.86407,0.86675,0.59652,0.59533,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30070,SRR27676309,SRX23343654,SRS20205505,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,RNA seq of atf7ip mt 2,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:72hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 2|id</u><u>:5</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,mRNAseq of atf7ip mt,RNA seq of atf7ip mt 2,RNA seq of atf7ip mt 2,mRNAseq of atf7ip mt of replicate 2,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,RNA-seq of atf7ip mt_2_R2.fastq.gz.gz RNA-seq of atf7ip mt_2_R1.fastq.gz.gz,fastq fastq,2881485000.0,9604950.0,RNA seq of atf7ip mt 2 R1.fastq.gz.gz,0:150 1:150,A:714870764;C:672086586;G:819085358;T:675370688;N:71604,150,150,,,714870764,672086586,819085358,675370688,71604,SRX23343654,SRS20205505,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.95105,0.94782,0.0877,0.08683,0.67838,0.68085,0.4943,0.49308,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30071,SRR27676310,SRX23343653,SRS20205506,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,RNA seq of atf7ip mt 1,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:72hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 1|id</u><u>:4</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,mRNAseq of atf7ip mt,RNA seq of atf7ip mt 1,RNA seq of atf7ip mt 1,mRNAseq of atf7ip mt of replicate 1,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,RNA-seq of atf7ip mt_1_R2.fastq.gz.gz RNA-seq of atf7ip mt_1_R1.fastq.gz.gz,fastq fastq,5215476900.0,17384923.0,RNA seq of atf7ip mt 1 R1.fastq.gz.gz,0:150 1:150,A:1305694077;C:1250588317;G:1437727006;T:1221425310;N:42190,150,150,,,1305694077,1250588317,1437727006,1221425310,42190,SRX23343653,SRS20205506,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.95459,0.9546,0.09418,0.0933,0.67353,0.67643,0.49356,0.49989,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30072,SRR27676311,SRX23343652,SRS20205507,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,RNA seq of atf7ip control 3,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:72hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 3|id</u><u>:3</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,mRNAseq of atf7ip control,RNA seq of atf7ip control 3,RNA seq of atf7ip control 3,mRNAseq of atf7ip control of replicate 3,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,RNA-seq of atf7ip control_3_R2.fastq.gz.gz RNA-seq of atf7ip control_3_R1.fastq.gz.gz,fastq fastq,6742549200.0,22475164.0,RNA seq of atf7ip control 3 R1.fastq.gz.gz,0:150 1:150,A:1698977237;C:1657996046;G:1800441072;T:1584967439;N:167406,150,150,,,1698977237,1657996046,1800441072,1584967439,167406,SRX23343652,SRS20205507,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.96114,0.9601,0.05191,0.05152,0.69219,0.69398,0.48597,0.48633,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30073,SRR27676312,SRX23343651,SRS20205504,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,RNA seq of atf7ip control 2,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:72hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 2|id</u><u>:2</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,mRNAseq of atf7ip control,RNA seq of atf7ip control 2,RNA seq of atf7ip control 2,mRNAseq of atf7ip control of replicate 2,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,RNA-seq of atf7ip control_2_R2.fastq.gz.gz RNA-seq of atf7ip control_2_R1.fastq.gz.gz,fastq fastq,6962540400.0,23208468.0,RNA seq of atf7ip control 2 R1.fastq.gz.gz,0:150 1:150,A:1794934846;C:1640272261;G:1855642638;T:1671491013;N:199642,150,150,,,1794934846,1640272261,1855642638,1671491013,199642,SRX23343651,SRS20205504,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.95531,0.95468,0.05949,0.05926,0.71019,0.71129,0.50401,0.50622,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
30074,SRR27676313,SRX23343650,SRS20205503,SRP485121,PRJNA1067443,RNA seq&smart seq&CUT TAG,PRJNA1067443,Other,RNA seq&amp;smart seq&amp;CUT TAG,,,,,RNA seq of atf7ip control 1,,strain:missing|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:missing|dev stage:72hpf|collection date:missing|geo loc name:missing|sex:pooled male and female|tissue:hematopoietic stem and progenitor cell|replicate:replicate = biological replicate 1|id</u><u>:1</u><u>|BioSampleModel:Model organism or animal,,,,,,,,,mRNAseq of atf7ip control,RNA seq of atf7ip control 1,RNA seq of atf7ip control 1,mRNAseq of atf7ip control of replicate 1,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP485121,,,RNA-seq of atf7ip control_1_R1.fastq.gz.gz RNA-seq of atf7ip control_1_R2.fastq.gz.gz,fastq fastq,8543359800.0,28477866.0,RNA seq of atf7ip control 1 R1.fastq.gz.gz,0:150 1:150,A:2200058170;C:2049588985;G:2219737118;T:2073765388;N:210139,150,150,,,2200058170,2049588985,2219737118,2073765388,210139,SRX23343650,SRS20205503,SRA1789215,East China Normal University|Institute of Biomedical Sciences,East China Normal University,2,0.96026,0.95618,0.05646,0.05613,0.68424,0.6856,0.48963,0.49334,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-01-22,Larval,Larval,Blood,Hematopoietic System
31530,SRR28467112,SRX24070103,SRS20860625,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPM 1,,strain:AB Wild type|isolate:Zebrafish of BPM treatment group 1|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPM 1,ZXY BPM 1,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPM1.raw_2.fastq.gz BPM1.raw_1.fastq.gz,fastq fastq,9394450800.0,31314836.0,BPM1.raw 1.fastq.gz,0:150 1:150,A:2554382711;C:2098883579;G:2207645797;T:2533462469;N:76244,150,150,,,2554382711,2098883579,2207645797,2533462469,76244,SRX24070103,SRS20860625,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94127,0.93972,0.1164,0.11723,0.67308,0.67673,0.49857,0.50613,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31531,SRR28467113,SRX24070102,SRS20860624,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPG 3,,strain:AB Wild type|isolate:Zebrafish of BPG treatment group 3|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPG 3,ZXY BPG 3,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPG3.raw_1.fastq.gz BPG3.raw_2.fastq.gz,fastq fastq,10077237000.0,33590790.0,BPG3.raw 1.fastq.gz,0:150 1:150,A:2739033278;C:2249842624;G:2379133275;T:2709150044;N:77779,150,150,,,2739033278,2249842624,2379133275,2709150044,77779,SRX24070102,SRS20860624,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94306,0.94056,0.10748,0.10702,0.67653,0.67986,0.5156,0.50914,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31532,SRR28467114,SRX24070101,SRS20860623,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPG 2,,strain:AB Wild type|isolate:Zebrafish of BPG treatment group 2|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPG 2,ZXY BPG 2,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPG2.raw_2.fastq.gz BPG2.raw_1.fastq.gz,fastq fastq,9510942300.0,31703141.0,BPG2.raw 1.fastq.gz,0:150 1:150,A:2596352503;C:2120752906;G:2233383807;T:2560375232;N:77852,150,150,,,2596352503,2120752906,2233383807,2560375232,77852,SRX24070101,SRS20860623,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94667,0.94269,0.10626,0.10688,0.67533,0.68081,0.49483,0.49423,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31533,SRR28467115,SRX24070100,SRS20860622,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPG 1,,strain:AB Wild type|isolate:Zebrafish of BPG treatment group 1|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPG 1,ZXY BPG 1,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPG1.raw_1.fastq.gz BPG1.raw_2.fastq.gz,fastq fastq,13070106300.0,43567021.0,BPG1.raw 1.fastq.gz,0:150 1:150,A:3534452437;C:2939996996;G:3085563305;T:3509989820;N:103742,150,150,,,3534452437,2939996996,3085563305,3509989820,103742,SRX24070100,SRS20860622,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.9438,0.94084,0.10523,0.10522,0.67829,0.68073,0.49381,0.49067,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31534,SRR28467116,SRX24070099,SRS20860621,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPA 3,,strain:AB Wild type|isolate:Zebrafish of BPA treatment group 3|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPA 3,ZXY BPA 3,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPA3.raw_2.fastq.gz BPA3.raw_1.fastq.gz,fastq fastq,10411684500.0,34705615.0,BPA3.raw 1.fastq.gz,0:150 1:150,A:2832043862;C:2321319365;G:2455663475;T:2802571018;N:86780,150,150,,,2832043862,2321319365,2455663475,2802571018,86780,SRX24070099,SRS20860621,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94457,0.94104,0.11054,0.10975,0.66994,0.67318,0.51406,0.50942,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31535,SRR28467117,SRX24070098,SRS20860620,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPA 2,,strain:AB Wild type|isolate:Zebrafish of BPA treatment group 2|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPA 2,ZXY BPA 2,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPA2.raw_1.fastq.gz BPA2.raw_2.fastq.gz,fastq fastq,9661415100.0,32204717.0,BPA2.raw 1.fastq.gz,0:150 1:150,A:2627401085;C:2157294589;G:2278953763;T:2597686452;N:79211,150,150,,,2627401085,2157294589,2278953763,2597686452,79211,SRX24070098,SRS20860620,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.9432,0.94024,0.10905,0.10878,0.67304,0.6775,0.50281,0.50407,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31536,SRR28467118,SRX24070097,SRS20860619,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPA 1,,strain:AB Wild type|isolate:Zebrafish of BPA treatment group 1|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPA 1,ZXY BPA 1,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPA1.raw_1.fastq.gz BPA1.raw_2.fastq.gz,fastq fastq,9717716400.0,32392388.0,BPA1.raw 1.fastq.gz,0:150 1:150,A:2650893145;C:2181496527;G:2254888972;T:2630357805;N:79951,150,150,,,2650893145,2181496527,2254888972,2630357805,79951,SRX24070097,SRS20860619,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94789,0.94422,0.10681,0.1065,0.66833,0.67377,0.50841,0.5025,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31537,SRR28467119,SRX24070096,SRS20860618,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,Control 3,,strain:AB Wild type|isolate:Zebrafish of blank control group 3|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY CK 3,ZXY CK 3,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,Control3.raw_1.fastq.gz Control3.raw_2.fastq.gz,fastq fastq,8827093200.0,29423644.0,Control3.raw 1.fastq.gz,0:150 1:150,A:2394211757;C:1989274047;G:2061489648;T:2382044834;N:72914,150,150,,,2394211757,1989274047,2061489648,2382044834,72914,SRX24070096,SRS20860618,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94786,0.9448,0.10432,0.10422,0.67221,0.67383,0.51187,0.50251,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31538,SRR28467120,SRX24070095,SRS20860617,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPTMC 3,,strain:AB Wild type|isolate:Zebrafish of BPTMC treatment group 3|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPTMC 3,ZXY BPTMC 3,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPTMC3.raw_1.fastq.gz BPTMC3.raw_2.fastq.gz,fastq fastq,10073599500.0,33578665.0,BPTMC3.raw 1.fastq.gz,0:150 1:150,A:2703808743;C:2256806609;G:2438554304;T:2674346802;N:83042,150,150,,,2703808743,2256806609,2438554304,2674346802,83042,SRX24070095,SRS20860617,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94379,0.89251,0.09996,0.09437,0.67961,0.68976,0.50126,0.51462,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31539,SRR28467121,SRX24070094,SRS20860616,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPTMC 2,,strain:AB Wild type|isolate:Zebrafish of BPTMC treatment group 2|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPTMC 2,ZXY BPTMC 2,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPTMC2.raw_1.fastq.gz BPTMC2.raw_2.fastq.gz,fastq fastq,9429771000.0,31432570.0,BPTMC2.raw 1.fastq.gz,0:150 1:150,A:2563993022;C:2099927909;G:2215282718;T:2550488919;N:78432,150,150,,,2563993022,2099927909,2215282718,2550488919,78432,SRX24070094,SRS20860616,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94015,0.93845,0.11202,0.11225,0.68142,0.68426,0.50947,0.46648,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31540,SRR28467122,SRX24070093,SRS20860615,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPTMC 1,,strain:AB Wild type|isolate:Zebrafish of BPTMC treatment group 1|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPTMC 1,ZXY BPTMC 1,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPTMC1.raw_1.fastq.gz BPTMC1.raw_2.fastq.gz,fastq fastq,10306275300.0,34354251.0,BPTMC1.raw 1.fastq.gz,0:150 1:150,A:2813926642;C:2292771191;G:2419432993;T:2780059784;N:84690,150,150,,,2813926642,2292771191,2419432993,2780059784,84690,SRX24070093,SRS20860615,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.9416,0.93867,0.11422,0.11418,0.68018,0.6856,0.48529,0.48762,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31541,SRR28467123,SRX24070092,SRS20860614,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPM 3,,strain:AB Wild type|isolate:Zebrafish of BPM treatment group 3|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPM 3,ZXY BPM 3,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPM3.raw_1.fastq.gz BPM3.raw_2.fastq.gz,fastq fastq,9935041500.0,33116805.0,BPM3.raw 1.fastq.gz,0:150 1:150,A:2699556183;C:2237493304;G:2314599682;T:2683312551;N:79780,150,150,,,2699556183,2237493304,2314599682,2683312551,79780,SRX24070092,SRS20860614,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94795,0.94397,0.10579,0.10508,0.67304,0.67614,0.48977,0.49037,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31542,SRR28467124,SRX24070091,SRS20860613,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,BPM 2,,strain:AB Wild type|isolate:Zebrafish of BPM treatment group 2|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY BPM 2,ZXY BPM 2,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,BPM2.raw_1.fastq.gz BPM2.raw_2.fastq.gz,fastq fastq,8645715900.0,28819053.0,BPM2.raw 1.fastq.gz,0:150 1:150,A:2370941492;C:1921770882;G:2002106055;T:2350824859;N:72612,150,150,,,2370941492,1921770882,2002106055,2350824859,72612,SRX24070091,SRS20860613,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94303,0.93986,0.1216,0.12095,0.67154,0.67385,0.4964,0.49763,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31543,SRR28467125,SRX24070090,SRS20860612,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,Control 2,,strain:AB Wild type|isolate:Zebrafish of blank control group 2|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY CK 2,ZXY CK 2,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,Control2.raw_1.fastq.gz Control2.raw_2.fastq.gz,fastq fastq,8728743900.0,29095813.0,Control2.raw 1.fastq.gz,0:150 1:150,A:2347809691;C:1937189854;G:2127437851;T:2316234453;N:72051,150,150,,,2347809691,1937189854,2127437851,2316234453,72051,SRX24070090,SRS20860612,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.94052,0.93739,0.10645,0.10488,0.67915,0.68377,0.51064,0.50924,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
31544,SRR28467126,SRX24070089,SRS20860611,SRP498043,PRJNA1091388,Danio rerio Raw sequence reads,PRJNA1091388,Whole Genome Sequencing,normal RNA seq of Danio rerio,,,,,Control 1,,strain:AB Wild type|isolate:Zebrafish of blank control group 1|breed:no collected|cultivar:no collected|ecotype:Nanjing|age:5 dpf stage:larval fish|collection date:2023 02|geo loc name:China: Nanjing|sex:not applicable|tissue:the whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Zebrafish larvae,ZXY CK 1,ZXY CK 1,Total RNA was isolated and purified from zebrafish roe tissues using TRIzol reagent.RNA quantity and purity were quantified using an ultra micro spectrophotometer  and agarose gel electrophoresis was used to avoid alteration of RNA integrity and purity. RNA and DNA were quantified using the Qubit 2.0 RNA and Qubit 2.0 DNA kits. Subsequently  the extracted RNA was transformed to construct cDNA sequencing libraries using the TrueLib mRNA Library Prep Kit for Illumina. post quantification and pooling of cDNA using AgilentBioAnalyzer 2100  sequencing was performed on NovaSeq 6000. The quality of sequencing data was assessed and low quality sequences were filtered by FastQC 0.11.9 and Trimmomatic 0.32. Filtered sequenced sequences were aligned with the zebrafish reference genome using HiSAT2 2.2.1  and finally transcripts were analyzed for gene expression levels by StringTie software,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP498043,,,Control1.raw_1.fastq.gz Control1.raw_2.fastq.gz,fastq fastq,13197587400.0,43991958.0,Control1.raw 1.fastq.gz,0:150 1:150,A:3499966481;C:3072967049;G:3152583762;T:3471963983;N:106125,150,150,,,3499966481,3072967049,3152583762,3471963983,106125,SRX24070089,SRS20860611,SRA1834298,Chinese Academy of Agricultural Sciences|Institute of Quality Standards and Testing Technol,Chinese Academy of Agricultural Sciences,2,0.9548,0.95216,0.08791,0.08792,0.66841,0.67241,0.48738,0.48068,150,150,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2024-03-27,Larval,Larval,Trunk,Surface Structure
33615,SRR30272850,SRX25733949,SRS22373737,SRP526812,PRJNA1148907,Single cell RNA sequencing to uncover tissue specific transcriptomic changes induced by perfluorooctanesulfonic acid PFOS in larval zebrafish Danio rerio,PRJNA1148907,Other,The aim is to to apply single cell RNA sequencing of zebrafish larvae to identify novel tissue specific mechanisms and processes following embryonic exposure to perfluorooctanesulfonic acid PFOS,,pubmed:39947082,,PFOS  S2,Sample2,,strain:Tgins:GFP zebrafish on an AB wildtype background|age:72 hpf|dev stage:protruding mouth stage|collection date:2023 01 03|geo loc name:USA: Massachusetts|sex:NA|tissue:whole body cells|treatment:PFOS 16 uM|BioSampleModel:Model organism or animal,,,,,,,,,PFOS,PFOS,PFOS,PFOS  S2  scRNAseq,,,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,PCR,PAIRED,ILLUMINA,NextSeq 500,,SRP526812,,,G194-S2-PFOS_S2_L001_R1_001.fastq.gz G194-S2-PFOS_S2_L001_R2_001.fastq.gz G194-S2-PFOS_S2_L002_R1_001.fastq.gz G194-S2-PFOS_S2_L002_R2_001.fastq.gz G194-S2-PFOS_S2_L003_R1_001.fastq.gz G194-S2-PFOS_S2_L003_R2_001.fastq.gz G194-S2-PFOS_S2_L004_R1_001.fastq.gz G194-S2-PFOS_S2_L004_R2_001.fastq.gz,fastq fastq fastq fastq fastq fastq fastq fastq,21751958340.0,184338630.0,G194 S2 PFOS S2 L001 R1 001.fastq.gz,0:28 1:90,A:6239773453;C:4634671870;G:5196638658;T:5672561386;N:8312973,28,90,,,6239773453,4634671870,5196638658,5672561386,8312973,SRX25733949,SRS22373737,SRA1949185,University of Massachusetts Amherst|Environmental Health Sciences,University of Massachusetts Amherst,2,0.01021,0.92344,0.00451,0.22962,0.99328,0.79847,0.28896,0.51751,28,90,T,B,sc-like readlen,illumina,nextseq,unknown,random_priming,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2024-08-16,Larval,Larval,Trunk,Surface Structure
33616,SRR30272851,SRX25733948,SRS22373736,SRP526812,PRJNA1148907,Single cell RNA sequencing to uncover tissue specific transcriptomic changes induced by perfluorooctanesulfonic acid PFOS in larval zebrafish Danio rerio,PRJNA1148907,Other,The aim is to to apply single cell RNA sequencing of zebrafish larvae to identify novel tissue specific mechanisms and processes following embryonic exposure to perfluorooctanesulfonic acid PFOS,,pubmed:39947082,,DMSO  S1,Sample1,,strain:Tgins:GFP zebrafish on an AB wildtype background|age:72 hpf|dev stage:protruding mouth stage|collection date:2023 01 03|geo loc name:USA: Massachusetts|sex:NA|tissue:whole body cells|treatment:DMSO 0.01%|BioSampleModel:Model organism or animal,,,,,,,,,DMSO,DMSO,DMSO,DMSO  S1  scRNAseq,,,RNA-Seq,TRANSCRIPTOMIC SINGLE CELL,PCR,PAIRED,ILLUMINA,NextSeq 500,,SRP526812,,,G194-S1-DMSO_S1_L001_R1_001.fastq.gz G194-S1-DMSO_S1_L001_R2_001.fastq.gz G194-S1-DMSO_S1_L002_R1_001.fastq.gz G194-S1-DMSO_S1_L002_R2_001.fastq.gz G194-S1-DMSO_S1_L003_R1_001.fastq.gz G194-S1-DMSO_S1_L003_R2_001.fastq.gz G194-S1-DMSO_S1_L004_R1_001.fastq.gz G194-S1-DMSO_S1_L004_R2_001.fastq.gz,fastq fastq fastq fastq fastq fastq fastq fastq,21636838838.0,183363041.0,G194 S1 DMSO S1 L001 R1 001.fastq.gz,0:28 1:90,A:6175214014;C:4647929260;G:5248646646;T:5556827078;N:8221840,28,90,,,6175214014,4647929260,5248646646,5556827078,8221840,SRX25733948,SRS22373736,SRA1949185,University of Massachusetts Amherst|Environmental Health Sciences,University of Massachusetts Amherst,2,0.01048,0.92488,0.00455,0.20966,0.99358,0.81464,0.28056,0.57876,28,90,T,B,sc-like readlen,illumina,nextseq,unknown,random_priming,unknown,sc,single_cell_generic,generic-scrnaseq-only,,United States,2024-08-16,Larval,Larval,Trunk,Surface Structure
33871,SRR30814554,SRX26215071,SRS22758079,SRP535175,PRJNA1165428,Danio rerio Transcriptome or Gene expression,PRJNA1165428,Other,RNA seq analysis reveals that genes associated with neural cell survival and differentiation are specifically affected in rfc2 KO zebrafish.,,,,KO3,KO3,,strain:AB|isolate:NA|breed:NA|cultivar:NA|ecotype:NA|age:NA|dev stage:4 dpf|collection date:2024 07 14|geo loc name:South Korea: Daejeon|sex:NA|tissue:Whole Organism|BioSampleModel:Model organism or animal,,,,,,,,,RNA seq of zebrafish rfc2 ko03,zf ko 03,zf ko 03,Paired end sequencing reads were generated on the Illumina sequencing NovaSeq platform. Cleaned reads were aligned to the Danio rerio GRCz11 using HISAT v2.1.0.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X,,SRP535175,,,KO3_1.fastq KO3_2.fastq,fastq fastq,6572467676.0,21763138.0,KO3 1.fastq,0:151 1:151,A:1814369939;C:1452368734;G:1505310751;T:1800408231;N:10021,151,151,,,1814369939,1452368734,1505310751,1800408231,10021,SRX26215071,SRS22758079,SRA1980706,Chungnam National University|Department of Biology,Chungnam National University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,South Korea,2024-09-27,Larval,Larval,Whole Organism,All anatomical structures
33872,SRR30814555,SRX26215070,SRS22758078,SRP535175,PRJNA1165428,Danio rerio Transcriptome or Gene expression,PRJNA1165428,Other,RNA seq analysis reveals that genes associated with neural cell survival and differentiation are specifically affected in rfc2 KO zebrafish.,,,,KO2,KO2,,strain:AB|isolate:NA|breed:NA|cultivar:NA|ecotype:NA|age:NA|dev stage:4 dpf|collection date:2024 07 12|geo loc name:South Korea: Daejeon|sex:NA|tissue:Whole Organism|BioSampleModel:Model organism or animal,,,,,,,,,RNA seq of zebrafish rfc2 ko02,zf ko 02,zf ko 02,Paired end sequencing reads were generated on the Illumina sequencing NovaSeq platform. Cleaned reads were aligned to the Danio rerio GRCz11 using HISAT v2.1.0.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X,,SRP535175,,,KO2_1.fastq KO2_2.fastq,fastq fastq,6712882576.0,22228088.0,KO2 1.fastq,0:151 1:151,A:1809986030;C:1515597384;G:1598845682;T:1788443120;N:10360,151,151,,,1809986030,1515597384,1598845682,1788443120,10360,SRX26215070,SRS22758078,SRA1980706,Chungnam National University|Department of Biology,Chungnam National University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,South Korea,2024-09-27,Larval,Larval,Whole Organism,All anatomical structures
33873,SRR30814556,SRX26215069,SRS22758076,SRP535175,PRJNA1165428,Danio rerio Transcriptome or Gene expression,PRJNA1165428,Other,RNA seq analysis reveals that genes associated with neural cell survival and differentiation are specifically affected in rfc2 KO zebrafish.,,,,KO1,KO1,,strain:AB|isolate:NA|breed:NA|cultivar:NA|ecotype:NA|age:NA|dev stage:4 dpf|collection date:2024 07 10|geo loc name:South Korea: Daejeon|sex:NA|tissue:Whole Organism|BioSampleModel:Model organism or animal,,,,,,,,,RNA seq of zebrafish rfc2 ko01,zf ko 01,zf ko 01,Paired end sequencing reads were generated on the Illumina sequencing NovaSeq platform. Cleaned reads were aligned to the Danio rerio GRCz11 using HISAT v2.1.0.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X,,SRP535175,,,KO1_1.fastq KO1_2.fastq,fastq fastq,6172941004.0,20440202.0,KO1 1.fastq,0:151 1:151,A:1700989337;C:1362585978;G:1431740094;T:1677616401;N:9194,151,151,,,1700989337,1362585978,1431740094,1677616401,9194,SRX26215069,SRS22758076,SRA1980706,Chungnam National University|Department of Biology,Chungnam National University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,South Korea,2024-09-27,Larval,Larval,Whole Organism,All anatomical structures
33874,SRR30814557,SRX26215068,SRS22758077,SRP535175,PRJNA1165428,Danio rerio Transcriptome or Gene expression,PRJNA1165428,Other,RNA seq analysis reveals that genes associated with neural cell survival and differentiation are specifically affected in rfc2 KO zebrafish.,,,,WT3,WT3,,strain:AB|isolate:NA|breed:NA|cultivar:NA|ecotype:NA|age:NA|dev stage:4 dpf|collection date:2024 07 08|geo loc name:South Korea: Daejeon|sex:NA|tissue:Whole Organism|BioSampleModel:Model organism or animal,,,,,,,,,RNA seq of zebrafish rfc2 wt03,zf wt 03,zf wt 03,Paired end sequencing reads were generated on the Illumina sequencing NovaSeq platform. Cleaned reads were aligned to the Danio rerio GRCz11 using HISAT v2.1.0.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X,,SRP535175,,,WT3_1.fastq WT3_2.fastq,fastq fastq,7481914402.0,24774551.0,WT3 1.fastq,0:151 1:151,A:2053911721;C:1669466343;G:1724274989;T:2034249790;N:11559,151,151,,,2053911721,1669466343,1724274989,2034249790,11559,SRX26215068,SRS22758077,SRA1980706,Chungnam National University|Department of Biology,Chungnam National University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,South Korea,2024-09-27,Larval,Larval,Whole Organism,All anatomical structures
33875,SRR30814558,SRX26215067,SRS22758074,SRP535175,PRJNA1165428,Danio rerio Transcriptome or Gene expression,PRJNA1165428,Other,RNA seq analysis reveals that genes associated with neural cell survival and differentiation are specifically affected in rfc2 KO zebrafish.,,,,WT2,WT2,,strain:AB|isolate:NA|breed:NA|cultivar:NA|ecotype:NA|age:NA|dev stage:4 dpf|collection date:2024 07 06|geo loc name:South Korea: Daejeon|sex:NA|tissue:Whole Organism|BioSampleModel:Model organism or animal,,,,,,,,,RNA seq of zebrafish rfc2 wt02,zf wt 02,zf wt 02,Paired end sequencing reads were generated on the Illumina sequencing NovaSeq platform. Cleaned reads were aligned to the Danio rerio GRCz11 using HISAT v2.1.0.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X,,SRP535175,,,WT2_1.fastq WT2_2.fastq,fastq fastq,7406291488.0,24524144.0,WT2 1.fastq,0:151 1:151,A:2028130386;C:1659349646;G:1712132015;T:2006666583;N:12858,151,151,,,2028130386,1659349646,1712132015,2006666583,12858,SRX26215067,SRS22758074,SRA1980706,Chungnam National University|Department of Biology,Chungnam National University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,South Korea,2024-09-27,Larval,Larval,Whole Organism,All anatomical structures
33876,SRR30814559,SRX26215066,SRS22758075,SRP535175,PRJNA1165428,Danio rerio Transcriptome or Gene expression,PRJNA1165428,Other,RNA seq analysis reveals that genes associated with neural cell survival and differentiation are specifically affected in rfc2 KO zebrafish.,,,,WT1,WT1,,strain:AB|isolate:NA|breed:NA|cultivar:NA|ecotype:NA|age:NA|dev stage:4 dpf|collection date:2024 07 04|geo loc name:South Korea: Daejeon|sex:NA|tissue:Whole Organism|BioSampleModel:Model organism or animal,,,,,,,,,RNA seq of zebrafish rfc2 wt01,zf wt 01,zf wt 01,Paired end sequencing reads were generated on the Illumina sequencing NovaSeq platform. Cleaned reads were aligned to the Danio rerio GRCz11 using HISAT v2.1.0.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X,,SRP535175,,,WT1_1.fastq WT1_2.fastq,fastq fastq,7226611756.0,23929178.0,WT1 1.fastq,0:151 1:151,A:1947187816;C:1649828636;G:1705449995;T:1924134231;N:11078,151,151,,,1947187816,1649828636,1705449995,1924134231,11078,SRX26215066,SRS22758075,SRA1980706,Chungnam National University|Department of Biology,Chungnam National University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,South Korea,2024-09-27,Larval,Larval,Whole Organism,All anatomical structures
33952,SRR31021716,SRX26408835,SRS22928744,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 1 1,P120 SME 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B335|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B335,B335,B335,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B335_S35_R1_001.fastq.gz B335_S35_R2_001.fastq.gz,fastq fastq,1692783800.0,16927838.0,B335 S35 R1 001.fastq.gz,0:50 1:50,A:435169158;C:407357709;G:414261716;T:435986654;N:8563,50,50,,,435169158,407357709,414261716,435986654,8563,SRX26408835,SRS22928744,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33953,SRR31021717,SRX26408834,SRS22928745,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 0.1 3,P120 SLO 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B334|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B334,B334,B334,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B334_S34_R1_001.fastq.gz B334_S34_R2_001.fastq.gz,fastq fastq,1886363200.0,18863632.0,B334 S34 R1 001.fastq.gz,0:50 1:50,A:490356255;C:449743241;G:455258475;T:490994958;N:10271,50,50,,,490356255,449743241,455258475,490994958,10271,SRX26408834,SRS22928745,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33954,SRR31021718,SRX26408833,SRS22928747,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 0.1 2,P120 SLO 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B333|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B333,B333,B333,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B333_S2_R1_001.fastq.gz B333_S2_R2_001.fastq.gz,fastq fastq,2051063200.0,20510632.0,B333 S2 R1 001.fastq.gz,0:50 1:50,A:537236574;C:487312859;G:489581035;T:536921586;N:11146,50,50,,,537236574,487312859,489581035,536921586,11146,SRX26408833,SRS22928747,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33955,SRR31021719,SRX26408832,SRS22928741,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 0.1 1,P120 SLO 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B332|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B332,B332,B332,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B332_S32_R1_001.fastq.gz B332_S32_R2_001.fastq.gz,fastq fastq,1902518500.0,19025185.0,B332 S32 R1 001.fastq.gz,0:50 1:50,A:496999311;C:450985865;G:457467495;T:497055262;N:10567,50,50,,,496999311,450985865,457467495,497055262,10567,SRX26408832,SRS22928741,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33956,SRR31021720,SRX26408831,SRS22928742,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 10 3,N120 WHI 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B358|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B358,B358,B358,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B358_S58_R1_001.fastq.gz B358_S58_R2_001.fastq.gz,fastq fastq,3412618400.0,34126184.0,B358 S58 R1 001.fastq.gz,0:50 1:50,A:882127346;C:817215325;G:830793970;T:882463986;N:17773,50,50,,,882127346,817215325,830793970,882463986,17773,SRX26408831,SRS22928742,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33957,SRR31021721,SRX26408830,SRS22928743,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 10 2,N120 WHI 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B357|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B357,B357,B357,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B357_S57_R1_001.fastq.gz B357_S57_R2_001.fastq.gz,fastq fastq,2930483600.0,29304836.0,B357 S57 R1 001.fastq.gz,0:50 1:50,A:758920208;C:700274298;G:712310919;T:758962702;N:15473,50,50,,,758920208,700274298,712310919,758962702,15473,SRX26408830,SRS22928743,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33958,SRR31021722,SRX26408829,SRS22928746,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 10 1,N120 WHI 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B356|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B356,B356,B356,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B356_S56_R1_001.fastq.gz B356_S56_R2_001.fastq.gz,fastq fastq,2284414000.0,22844140.0,B356 S56 R1 001.fastq.gz,0:50 1:50,A:594288899;C:544894478;G:551263068;T:593955741;N:11814,50,50,,,594288899,544894478,551263068,593955741,11814,SRX26408829,SRS22928746,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33959,SRR31021723,SRX26408828,SRS22928740,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 1 3,N120 WME 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B355|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B355,B355,B355,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B355_S55_R1_001.fastq.gz B355_S55_R2_001.fastq.gz,fastq fastq,2176173500.0,21761735.0,B355 S55 R1 001.fastq.gz,0:50 1:50,A:566136122;C:518747894;G:524997369;T:566280934;N:11181,50,50,,,566136122,518747894,524997369,566280934,11181,SRX26408828,SRS22928740,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33960,SRR31021724,SRX26408827,SRS22928739,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 1 2,N120 WME 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B354|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B354,B354,B354,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B354_S54_R1_001.fastq.gz B354_S54_R2_001.fastq.gz,fastq fastq,1453456700.0,14534567.0,B354 S54 R1 001.fastq.gz,0:50 1:50,A:372508432;C:352568689;G:356955359;T:371416134;N:8086,50,50,,,372508432,352568689,356955359,371416134,8086,SRX26408827,SRS22928739,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33961,SRR31021725,SRX26408826,SRS22928748,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 1 1,N120 WME 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B353|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B353,B353,B353,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B353_S53_R1_001.fastq.gz B353_S53_R2_001.fastq.gz,fastq fastq,1650491800.0,16504918.0,B353 S53 R1 001.fastq.gz,0:50 1:50,A:425690515;C:395504907;G:402582077;T:426705722;N:8579,50,50,,,425690515,395504907,402582077,426705722,8579,SRX26408826,SRS22928748,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33962,SRR31021726,SRX26408825,SRS22928738,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 0.1 3,N120 WLO 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B352|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B352,B352,B352,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B352_S52_R1_001.fastq.gz B352_S52_R2_001.fastq.gz,fastq fastq,1346045100.0,13460451.0,B352 S52 R1 001.fastq.gz,0:50 1:50,A:346386405;C:323951010;G:329014244;T:346686818;N:6623,50,50,,,346386405,323951010,329014244,346686818,6623,SRX26408825,SRS22928738,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33963,SRR31021727,SRX26408824,SRS22928737,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 0.1 2,N120 WLO 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B351|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B351,B351,B351,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B351_S51_R1_001.fastq.gz B351_S51_R2_001.fastq.gz,fastq fastq,1506763300.0,15067633.0,B351 S51 R1 001.fastq.gz,0:50 1:50,A:388854340;C:361527972;G:367405227;T:388967763;N:7998,50,50,,,388854340,361527972,367405227,388967763,7998,SRX26408824,SRS22928737,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33964,SRR31021728,SRX26408823,SRS22928735,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,NH2 0.1 1,N120 WLO 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B350|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B350,B350,B350,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B350_S50_R1_001.fastq.gz B350_S50_R2_001.fastq.gz,fastq fastq,1428442600.0,14284426.0,B350 S50 R1 001.fastq.gz,0:50 1:50,A:366939696;C:343871821;G:350258778;T:367364804;N:7501,50,50,,,366939696,343871821,350258778,367364804,7501,SRX26408823,SRS22928735,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33965,SRR31021729,SRX26408822,SRS22928736,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 10 3,C120 THI 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B349|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B349,B349,B349,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B349_S49_R1_001.fastq.gz B349_S49_R2_001.fastq.gz,fastq fastq,1550515000.0,15505150.0,B349 S49 R1 001.fastq.gz,0:50 1:50,A:403378506;C:368600965;G:373988430;T:404539249;N:7850,50,50,,,403378506,368600965,373988430,404539249,7850,SRX26408822,SRS22928736,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33966,SRR31021730,SRX26408821,SRS22928734,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,Control 3,Z120 C 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B331|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B331,B331,B331,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B331_S31_R1_001.fastq.gz B331_S31_R2_001.fastq.gz,fastq fastq,2108365300.0,21083653.0,B331 S31 R1 001.fastq.gz,0:50 1:50,A:542633636;C:506240722;G:516054000;T:543425824;N:11118,50,50,,,542633636,506240722,516054000,543425824,11118,SRX26408821,SRS22928734,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33967,SRR31021731,SRX26408820,SRS22928733,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 10 2,C120 THI 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B348|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B348,B348,B348,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B348_S48_R1_001.fastq.gz B348_S48_R2_001.fastq.gz,fastq fastq,1606689800.0,16066898.0,B348 S48 R1 001.fastq.gz,0:50 1:50,A:417464063;C:382987928;G:388189552;T:418040054;N:8203,50,50,,,417464063,382987928,388189552,418040054,8203,SRX26408820,SRS22928733,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33968,SRR31021732,SRX26408819,SRS22928728,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 10 1,C120 THI 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B347|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B347,B347,B347,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B347_S47_R1_001.fastq.gz B347_S47_R2_001.fastq.gz,fastq fastq,2913827500.0,29138275.0,B347 S47 R1 001.fastq.gz,0:50 1:50,A:761302997;C:691474819;G:698510506;T:762523760;N:15418,50,50,,,761302997,691474819,698510506,762523760,15418,SRX26408819,SRS22928728,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33969,SRR31021733,SRX26408818,SRS22928725,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 1 3,C120 TME 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B346|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B346,B346,B346,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B346_S46_R1_001.fastq.gz B346_S46_R2_001.fastq.gz,fastq fastq,3160750400.0,31607504.0,B346 S46 R1 001.fastq.gz,0:50 1:50,A:813674918;C:759351240;G:773075909;T:814631535;N:16798,50,50,,,813674918,759351240,773075909,814631535,16798,SRX26408818,SRS22928725,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33970,SRR31021734,SRX26408817,SRS22928732,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 1 2,C120 TME 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B345|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B345,B345,B345,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B345_S45_R1_001.fastq.gz B345_S45_R2_001.fastq.gz,fastq fastq,2914635800.0,29146358.0,B345 S45 R1 001.fastq.gz,0:50 1:50,A:746949857;C:703501695;G:715761917;T:748406578;N:15753,50,50,,,746949857,703501695,715761917,748406578,15753,SRX26408817,SRS22928732,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33971,SRR31021735,SRX26408816,SRS22928731,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 1 1,C120 TME 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B344|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B344,B344,B344,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B344_S44_R1_001.fastq.gz B344_S44_R2_001.fastq.gz,fastq fastq,4554368900.0,45543689.0,B344 S44 R1 001.fastq.gz,0:50 1:50,A:1165101493;C:1101095529;G:1122931150;T:1165217834;N:22894,50,50,,,1165101493,1101095529,1122931150,1165217834,22894,SRX26408816,SRS22928731,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33972,SRR31021736,SRX26408815,SRS22928729,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 0.1 3,C120 TLO 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B343|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B343,B343,B343,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B343_S43_R1_001.fastq.gz B343_S43_R2_001.fastq.gz,fastq fastq,2380475200.0,23804752.0,B343 S43 R1 001.fastq.gz,0:50 1:50,A:607581751;C:575091547;G:590138251;T:607650992;N:12659,50,50,,,607581751,575091547,590138251,607650992,12659,SRX26408815,SRS22928729,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33973,SRR31021737,SRX26408814,SRS22928730,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 0.1 2,C120 TLO 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B342|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B342,B342,B342,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B342_S42_R1_001.fastq.gz B342_S42_R2_001.fastq.gz,fastq fastq,3651867700.0,36518677.0,B342 S42 R1 001.fastq.gz,0:50 1:50,A:932588654;C:882930334;G:902681378;T:933649498;N:17836,50,50,,,932588654,882930334,902681378,933649498,17836,SRX26408814,SRS22928730,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33974,SRR31021738,SRX26408813,SRS22928723,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,COOH 0.1 1,C120 TLO 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B341|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B341,B341,B341,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B341_S3_R1_001.fastq.gz B341_S3_R2_001.fastq.gz,fastq fastq,2777695600.0,27776956.0,B341 S3 R1 001.fastq.gz,0:50 1:50,A:703256824;C:685127064;G:689608205;T:699688785;N:14722,50,50,,,703256824,685127064,689608205,699688785,14722,SRX26408813,SRS22928723,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33975,SRR31021739,SRX26408812,SRS22928727,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 10 3,P120 SHI 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B340|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B340,B340,B340,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B340_S40_R1_001.fastq.gz B340_S40_R2_001.fastq.gz,fastq fastq,2893779400.0,28937794.0,B340 S40 R1 001.fastq.gz,0:50 1:50,A:751721935;C:690399655;G:699481416;T:752160975;N:15419,50,50,,,751721935,690399655,699481416,752160975,15419,SRX26408812,SRS22928727,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33976,SRR31021740,SRX26408811,SRS22928720,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 10 1,P120 SHI 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B338|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B338,B338,B338,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B338_S38_R1_001.fastq.gz B338_S38_R2_001.fastq.gz,fastq fastq,2525250300.0,25252503.0,B338 S38 R1 001.fastq.gz,0:50 1:50,A:654388023;C:601232675;G:613558159;T:656058712;N:12731,50,50,,,654388023,601232675,613558159,656058712,12731,SRX26408811,SRS22928720,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33977,SRR31021741,SRX26408810,SRS22928724,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 1 3,P120 SME 3,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B337|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B337,B337,B337,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B337_S37_R1_001.fastq.gz B337_S37_R2_001.fastq.gz,fastq fastq,2482377400.0,24823774.0,B337 S37 R1 001.fastq.gz,0:50 1:50,A:643559426;C:592015685;G:602120561;T:644668977;N:12751,50,50,,,643559426,592015685,602120561,644668977,12751,SRX26408810,SRS22928724,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33978,SRR31021742,SRX26408809,SRS22928722,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 1 2,P120 SME 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B336|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B336,B336,B336,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B336_S36_R1_001.fastq.gz B336_S36_R2_001.fastq.gz,fastq fastq,1946578400.0,19465784.0,B336 S36 R1 001.fastq.gz,0:50 1:50,A:504859512;C:464724973;G:471834380;T:505149326;N:10209,50,50,,,504859512,464724973,471834380,505149326,10209,SRX26408809,SRS22928722,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33979,SRR31021743,SRX26408808,SRS22928726,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,PS 10 2,P120 SHI 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B339|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B339,B339,B339,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B339_S39_R1_001.fastq.gz B339_S39_R2_001.fastq.gz,fastq fastq,2199002900.0,21990029.0,B339 S39 R1 001.fastq.gz,0:50 1:50,A:570993329;C:523663058;G:532594297;T:571740868;N:11348,50,50,,,570993329,523663058,532594297,571740868,11348,SRX26408808,SRS22928726,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33980,SRR31021744,SRX26408807,SRS22928721,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,Control 2,Z120 C 2,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B330|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B330,B330,B330,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B330_S1_R1_001.fastq.gz B330_S1_R2_001.fastq.gz,fastq fastq,2070472100.0,20704721.0,B330 S1 R1 001.fastq.gz,0:50 1:50,A:537760107;C:494573795;G:500793218;T:537333858;N:11122,50,50,,,537760107,494573795,500793218,537333858,11122,SRX26408807,SRS22928721,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
33981,SRR31021745,SRX26408806,SRS22928719,SRP539040,PRJNA1173915,Revealing hidden plastics using Trinal Oviparous Omics Model TriOOL,PRJNA1173915,Other,This project builds on strong interdisciplinary technologies and international expertise to explore frontiers of nanoplastic pollution issues  by integrating comparative model embryos  cutting edge bioimaging  omics  and hazard modelLing. The project will provide unprecedented insights into understanding the potential hazards posed by nanoplastics and corresponding mechanisms and launch a new chapter in the toxicological assessment of nanopollutant mixtures.,,,,Control 1,Z120 C 1,,strain:Wide AB|isolate:Wide type AB strain|breed:live Artemia and dry flake food|cultivar:missing|ecotype:Denmark|age:120 hpf|dev stage:larvae|collection date:2022 04|geo loc name:Denmark: Odense|sex:pooled male and female|tissue:whole organism|source material id:B329|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zebrafish: B329,B329,B329,RNA was isolated and purified by the RNeasy Mini Kit Qiagen  Germany with three replicates per group. Total RNA quality was assessed using RNA agarose gel electrophoresis  and RNA quantity was determined using a spectrofluorometer MySpec  VWR  Radnor  United States. Complementary DNA cDNA and the generated libraries were prepared according to the manufacture protocol and sequenced using the Illumina NovaSeq 6000sequencing platforms at the University of Southern Denmark.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina MiSeq,,SRP539040,,,B329_S29_R1_001.fastq.gz B329_S29_R2_001.fastq.gz,fastq fastq,2846303000.0,28463030.0,B329 S29 R1 001.fastq.gz,0:50 1:50,A:732723326;C:679449612;G:698675459;T:735439047;N:15556,50,50,,,732723326,679449612,698675459,735439047,15556,SRX26408806,SRS22928719,SRA1992799,University of Southern Denmark|Department of Biology,University of Southern Denmark,,,,,,,,,,,,B,B,biological fallback assumption,illumina,miseq,unknown,random_priming,unknown,bulk,unknown,unknown,,Denmark,2024-10-17,Larval,Larval,Whole Organism,All anatomical structures
34605,SRR32129951,SRX27476252,SRS23900301,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,LAP3,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 9|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,LAP3,LAP3,mRNA seq of Danio rerio  relication 3 of LAP,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,SLAP3.R1.raw.fastq.gz SLAP3.R2.raw.fastq.gz,fastq fastq,7183254522.0,23785611.0,SLAP3.R1.raw.fastq.gz,0:151 1:151,A:1882819072;C:1681966830;G:1744461184;T:1873823146;N:184290,151,151,,,1882819072,1681966830,1744461184,1873823146,184290,SRX27476252,SRS23900301,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34606,SRR32129952,SRX27476251,SRS23900300,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,LAP2,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 8|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,LAP2,LAP2,mRNA seq of Danio rerio  relication 2 of LAP,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,SLAP2.R1.raw.fastq.gz SLAP2.R2.raw.fastq.gz,fastq fastq,7139867692.0,23641946.0,SLAP2.R1.raw.fastq.gz,0:151 1:151,A:1904886971;C:1644487548;G:1698548524;T:1891760900;N:183749,151,151,,,1904886971,1644487548,1698548524,1891760900,183749,SRX27476251,SRS23900300,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34607,SRR32129953,SRX27476250,SRS23900299,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,LAP1,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 7|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,LAP1,LAP1,mRNA seq of Danio rerio  relication 1 of LAP,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,SLAP1.R1.raw.fastq.gz SLAP1.R2.raw.fastq.gz,fastq fastq,7645904026.0,25317563.0,SLAP1.R1.raw.fastq.gz,0:151 1:151,A:2049503194;C:1744624826;G:1812871140;T:2038707095;N:197771,151,151,,,2049503194,1744624826,1812871140,2038707095,197771,SRX27476250,SRS23900299,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34608,SRR32129954,SRX27476249,SRS23900298,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,TWP3,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 6|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,TWP3,TWP3,mRNA seq of Danio rerio  relication 3 of TWP,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,STWP3.R1.raw.fastq.gz STWP3.R2.raw.fastq.gz,fastq fastq,8096479268.0,26809534.0,STWP3.R1.raw.fastq.gz,0:151 1:151,A:2110740470;C:1903775486;G:1969223430;T:2112536317;N:203565,151,151,,,2110740470,1903775486,1969223430,2112536317,203565,SRX27476249,SRS23900298,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34609,SRR32129955,SRX27476248,SRS23900297,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,TWP2,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 5|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,TWP2,TWP2,mRNA seq of Danio rerio  relication 2 of TWP,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,STWP2.R1.raw.fastq.gz STWP2.R2.raw.fastq.gz,fastq fastq,6881487968.0,22786384.0,STWP2.R1.raw.fastq.gz,0:151 1:151,A:1769568137;C:1637920699;G:1700276394;T:1773546973;N:175765,151,151,,,1769568137,1637920699,1700276394,1773546973,175765,SRX27476248,SRS23900297,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34610,SRR32129956,SRX27476247,SRS23900296,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,TWP1,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 4|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,TWP1,TWP1,mRNA seq of Danio rerio  relication 1 of TWP,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,STWP1.R1.raw.fastq.gz STWP1.R2.raw.fastq.gz,fastq fastq,8138908456.0,26950028.0,STWP1.R1.raw.fastq.gz,0:151 1:151,A:2098817113;C:1934858897;G:2002571746;T:2102461754;N:198946,151,151,,,2098817113,1934858897,2002571746,2102461754,198946,SRX27476247,SRS23900296,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34611,SRR32129957,SRX27476246,SRS23900295,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,CONTROL3,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 3|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,CONTROL3,CONTROL3,mRNA seq of Danio rerio  relication 3 of CONTROL,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,CONTROL3.R1.raw.fastq.gz CONTROL3.R2.raw.fastq.gz,fastq fastq,7576728510.0,25088505.0,CONTROL3.R1.raw.fastq.gz,0:151 1:151,A:1944933324;C:1805382406;G:1877636209;T:1948585527;N:191044,151,151,,,1944933324,1805382406,1877636209,1948585527,191044,SRX27476246,SRS23900295,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34612,SRR32129958,SRX27476245,SRS23900294,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,CONTROL2,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 2|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,CONTROL2,CONTROL2,mRNA seq of Danio rerio  relication 2 of CONTROL,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,CONTROL2.R1.raw.fastq.gz CONTROL2.R2.raw.fastq.gz,fastq fastq,8261380328.0,27355564.0,CONTROL2.R1.raw.fastq.gz,0:151 1:151,A:2215199676;C:1884149053;G:1947224290;T:2214596047;N:211262,151,151,,,2215199676,1884149053,1947224290,2214596047,211262,SRX27476245,SRS23900294,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
34613,SRR32129959,SRX27476244,SRS23900293,SRP559953,PRJNA1215813,Comparative Toxicological Effects of Tire Wear and Latex Particle Leachates in Zebrafish Embryos: Focus on Oxidative Stress and Ferroptosis,PRJNA1215813,Other,Microrubber  a subset of microplastics  has emerged as a significant environmental concern due to its persistence  bioaccumulation  and potential toxicity in aquatic ecosystems. This study investigates the toxicological effects of leachates derived from tire wear particles TWP and latex particles LAP on zebrafish embryos  focusing on physiological  oxidative stress  and transcriptomic responses. LAP leachate exhibited significantly higher toxicity than TWP  characterized by increased mortality  delayed hatching  reduced spontaneous movement  suppressed heart rate  and severe morphological malformations. Chemical analysis identified elevated levels of heavy metals and biologically active organic compounds  with higher zinc concentrations and benzothiazole derivatives in LAP leachate contributing to its greater toxicity. Oxidative stress markers revealed elevated catalase CAT and malondialdehyde MDA levels in both groups  but LAP exposure significantly reduced glutathione S transferase GST activity  indicating compromised detoxification capacity. Transcriptomic analysis identified ferroptosis as a central pathway mediating toxicity in both leachates. LAP exposure was associated with the upregulation of mt2 and fthl31 and the downregulation of slc40a1  suggesting disrupted iron metabolism and exacerbated oxidative damage. In contrast  TWP exposure triggered adaptive responses  including the upregulation of detoxification related genes such as cyp1a and gstt1b. These findings elucidate distinct toxicity mechanisms between TWP and LAP leachates and underscore the need for enhanced environmental monitoring and regulatory strategies to mitigate their ecological impacts.,,,,,CONTROL1,,breed:AB|age:5 days|collection date:2024 05 26|geo loc name:Not collected|sex:Missing|tissue:Whole body|Replicate:Replicate = biological replicate 1|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of danio rerio: zebrafish embryos,CONTROL1,CONTROL1,mRNA seq of Danio rerio  relication 1 of CONTROL,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq X Plus,,SRP559953,,,CONTROL1.R1.raw.fastq.gz CONTROL1.R2.raw.fastq.gz,fastq fastq,7297086174.0,24162537.0,CONTROL1.R1.raw.fastq.gz,0:151 1:151,A:1869599378;C:1745386867;G:1807178668;T:1874732590;N:188671,151,151,,,1869599378,1745386867,1807178668,1874732590,188671,SRX27476244,SRS23900293,SRA2060932,Qingdao University of Science and Technology|College of Marine Science and biological engineeri,Qingdao University of Science and Technology,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2025-01-26,Larval,Larval,Trunk,Surface Structure
36223,SRR33596639,SRX28826240,SRS25059183,SRP585802,PRJNA1263632,transcriptome analysis of cu693494.2 ORF3 mutant,PRJNA1263632,Other,The 3 dpf cu693494.2 ORF3 /  and WT larvae were dark treated 1day  and the zebrafish samples were collected at CT4/100 hpf  each with duplicate samples.,,,,,cu ORF3 CT4 2,,strain:AB|age:3 dpf|dev stage:100 hpf|collection date:2024 10 30|geo loc name:China:Suzhu|sex:not determined|tissue:whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: whole body,treatment2,treatment2,RNA,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP585802,,,cu-orf3-ct4-2_L1_1.fq.gz cu-orf3-ct4-2_L1_2.fq.gz,fastq fastq,6171131100.0,20570437.0,cu orf3 ct4 2 L1 1.fq.gz,0:150 1:150,A:1712348536;C:1373082573;G:1411350014;T:1674292589;N:57388,150,150,,,1712348536,1373082573,1411350014,1674292589,57388,SRX28826240,SRS25059183,SRA2130944,Soochow University|Center for Circadian Clocks,Soochow University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,Unknown,2025-05-16,Larval,Larval,Trunk,Surface Structure
36224,SRR33596640,SRX28826239,SRS25059182,SRP585802,PRJNA1263632,transcriptome analysis of cu693494.2 ORF3 mutant,PRJNA1263632,Other,The 3 dpf cu693494.2 ORF3 /  and WT larvae were dark treated 1day  and the zebrafish samples were collected at CT4/100 hpf  each with duplicate samples.,,,,,cu ORF3 CT4 1,,strain:AB|age:3 dpf|dev stage:100 hpf|collection date:2024 10 29|geo loc name:China:Suzhu|sex:not determined|tissue:whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: whole body,treatment1,treatment1,RNA,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP585802,,,cu-orf3-ct4-1_L1_1.fq.gz cu-orf3-ct4-1_L1_2.fq.gz,fastq fastq,5416142700.0,18053809.0,cu orf3 ct4 1 L1 1.fq.gz,0:150 1:150,A:1506288932;C:1201904939;G:1238064656;T:1469832889;N:51284,150,150,,,1506288932,1201904939,1238064656,1469832889,51284,SRX28826239,SRS25059182,SRA2130944,Soochow University|Center for Circadian Clocks,Soochow University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,Unknown,2025-05-16,Larval,Larval,Trunk,Surface Structure
36225,SRR33596641,SRX28826238,SRS25059181,SRP585802,PRJNA1263632,transcriptome analysis of cu693494.2 ORF3 mutant,PRJNA1263632,Other,The 3 dpf cu693494.2 ORF3 /  and WT larvae were dark treated 1day  and the zebrafish samples were collected at CT4/100 hpf  each with duplicate samples.,,,,,WT CT4 2,,strain:AB|age:3 dpf|dev stage:100 hpf|collection date:2024 10 28|geo loc name:China:Suzhu|sex:not determined|tissue:whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: whole body,control2,control2,RNA,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP585802,,,wt-ct4-2_L1_1.fq.gz wt-ct4-2_L1_2.fq.gz,fastq fastq,6965839200.0,23219464.0,wt ct4 2 L1 1.fq.gz,0:150 1:150,A:1904316669;C:1579337292;G:1621119016;T:1860980311;N:85912,150,150,,,1904316669,1579337292,1621119016,1860980311,85912,SRX28826238,SRS25059181,SRA2130944,Soochow University|Center for Circadian Clocks,Soochow University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,Unknown,2025-05-16,Larval,Larval,Trunk,Surface Structure
36226,SRR33596642,SRX28826237,SRS25059180,SRP585802,PRJNA1263632,transcriptome analysis of cu693494.2 ORF3 mutant,PRJNA1263632,Other,The 3 dpf cu693494.2 ORF3 /  and WT larvae were dark treated 1day  and the zebrafish samples were collected at CT4/100 hpf  each with duplicate samples.,,,,,WT CT4 1,,strain:AB|age:3 dpf|dev stage:100 hpf|collection date:2024 10 27|geo loc name:China:Suzhu|sex:not determined|tissue:whole body|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of Danio rerio: whole body,control1,control1,RNA,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina NovaSeq 6000,,SRP585802,,,wt-ct4-1_L1_1.fq.gz wt-ct4-1_L1_2.fq.gz,fastq fastq,5399973600.0,17999912.0,wt ct4 1 L1 1.fq.gz,0:150 1:150,A:1487700688;C:1212118655;G:1244330905;T:1455775411;N:47941,150,150,,,1487700688,1212118655,1244330905,1455775411,47941,SRX28826237,SRS25059180,SRA2130944,Soochow University|Center for Circadian Clocks,Soochow University,,,,,,,,,,,,B,B,biological fallback assumption,illumina,novaseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,Unknown,2025-05-16,Larval,Larval,Trunk,Surface Structure
48313,SRR7223661,SRX4130205,SRS3344559,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,TrisCDPS1,,strain:Danio rerio|age:14 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of TrisCDPS treated zf: 5 day larvae,TrisCDPS1,TrisCDPS1,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,TrisCDPS1_2.fq.gz TrisCDPS1_1.fq.gz,fastq fastq,7552017900.0,25173393.0,TrisCDPS1 2.fq.gz,0:150 1:150,A:2064740694;C:1718323084;G:1724225343;T:2043708648;N:1020131,150,150,,,2064740694,1718323084,1724225343,2043708648,1020131,SRX4130205,SRS3344559,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92864,0.92381,0.09537,0.09435,0.71086,0.71467,0.47551,0.47766,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48314,SRR7223662,SRX4130204,SRS3344558,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,DCDPS3,,strain:Danio rerio|age:13 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of DCDPS treated zf: 5 day larvae,DCDPS3,DCDPS3,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,DCDPS3_1.fq.gz DCDPS3_2.fq.gz,fastq fastq,8882830500.0,29609435.0,DCDPS3 2.fq.gz,0:150 1:150,A:2427234479;C:2021300509;G:2031701758;T:2401395227;N:1198527,150,150,,,2427234479,2021300509,2031701758,2401395227,1198527,SRX4130204,SRS3344558,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92596,0.91455,0.09347,0.09189,0.7108,0.71478,0.47276,0.48212,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48315,SRR7223663,SRX4130203,SRS3344557,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,TCDPS1,,strain:Danio rerio|age:8 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of TCDPS treated zf: 5 day larvae,TCDPS1,TCDPS1,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,TCDPS1_1.fq.gz TCDPS1_2.fq.gz,fastq fastq,7523076900.0,25076923.0,TCDPS1 1.fq.gz,0:150 1:150,A:2038154575;C:1731802031;G:1735048059;T:2017093917;N:978318,150,150,,,2038154575,1731802031,1735048059,2017093917,978318,SRX4130203,SRS3344557,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92608,0.92913,0.08659,0.08656,0.71425,0.71721,0.46846,0.46712,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48316,SRR7223664,SRX4130202,SRS3344556,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,C3,,strain:Danio rerio|age:7 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zf: 5 day larvae,C3,C3,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,C3_1.fq.gz C3_2.fq.gz,fastq fastq,6543797400.0,21812658.0,C3 2.fq.gz,0:150 1:150,A:1738781839;C:1536296581;G:1551651858;T:1716817665;N:249457,150,150,,,1738781839,1536296581,1551651858,1716817665,249457,SRX4130202,SRS3344556,SRA711726,University of Jinan|Environment,University of Jinan,2,0.93202,0.93617,0.06777,0.06811,0.71064,0.71892,0.47813,0.47374,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48317,SRR7223665,SRX4130201,SRS3344555,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,C2,,strain:Danio rerio|age:6 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zf: 5 day larvae,C2,C2,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,C2_1.fq.gz C2_2.fq.gz,fastq fastq,7622981400.0,25409938.0,C2 1.fq.gz,0:150 1:150,A:2078412920;C:1740455140;G:1746462300;T:2056660891;N:990149,150,150,,,2078412920,1740455140,1746462300,2056660891,990149,SRX4130201,SRS3344555,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92699,0.92374,0.09404,0.09306,0.71234,0.71622,0.46627,0.46522,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48318,SRR7223666,SRX4130200,SRS3344554,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,C1,,strain:Danio rerio|age:5 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of zf: 5 day larvae,C1,C1,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,C1_1.fq.gz C1_2.fq.gz,fastq fastq,6629787900.0,22099293.0,C1 1.fq.gz,0:150 1:150,A:1835589982;C:1485010662;G:1491104537;T:1817331587;N:751132,150,150,,,1835589982,1485010662,1491104537,1817331587,751132,SRX4130200,SRS3344554,SRA711726,University of Jinan|Environment,University of Jinan,2,0.89108,0.88492,0.09317,0.09156,0.718,0.7233,0.47294,0.47377,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48319,SRR7223667,SRX4130199,SRS3344553,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,DCDPS2,,strain:Danio rerio|age:12 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of DCDPS treated zf: 5 day larvae,DCDPS2,DCDPS2,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,DCDPS2_1.fq.gz DCDPS2_2.fq.gz,fastq fastq,8040624600.0,26802082.0,DCDPS2 1.fq.gz,0:150 1:150,A:2205838635;C:1822959368;G:1832567991;T:2178177040;N:1081566,150,150,,,2205838635,1822959368,1832567991,2178177040,1081566,SRX4130199,SRS3344553,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92586,0.92198,0.09355,0.09254,0.71078,0.71652,0.47953,0.47275,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48320,SRR7223668,SRX4130198,SRS3344552,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,DCDPS1,,strain:Danio rerio|age:11 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of DCDPS treated zf: 5 day larvae,DCDPS1,DCDPS1,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,DCDPS1_2.fq.gz DCDPS1_1.fq.gz,fastq fastq,8599461900.0,28664873.0,DCDPS1 2.fq.gz,0:150 1:150,A:2345534916;C:1963958724;G:1968901667;T:2319904936;N:1161657,150,150,,,2345534916,1963958724,1968901667,2319904936,1161657,SRX4130198,SRS3344552,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92368,0.92723,0.08764,0.08731,0.71547,0.71971,0.4813,0.47995,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-05-27,Larval,Larval,Whole Organism,All anatomical structures
48321,SRR7223669,SRX4130197,SRS3344551,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,TCDPS3,,strain:Danio rerio|age:10 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of TCDPS treated zf: 5 day larvae,TCDPS3,TCDPS3,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,TCDPS3_1.fq.gz TCDPS3_2.fq.gz,fastq fastq,7963502100.0,26545007.0,TCDPS3 2.fq.gz,0:150 1:150,A:2163154757;C:1827132936;G:1831483410;T:2140658978;N:1072019,150,150,,,2163154757,1827132936,1831483410,2140658978,1072019,SRX4130197,SRS3344551,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92803,0.92935,0.08694,0.08709,0.71157,0.71543,0.4691,0.46764,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48322,SRR7223670,SRX4130196,SRS3344550,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,TCDPS2,,strain:Danio rerio|age:9 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of TCDPS treated zf: 5 day larvae,TCDPS2,TCDPS2,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,TCDPS2_1.fq.gz TCDPS2_2.fq.gz,fastq fastq,8080785600.0,26935952.0,TCDPS2 2.fq.gz,0:150 1:150,A:2207688944;C:1842341306;G:1846129472;T:2183533934;N:1091944,150,150,,,2207688944,1842341306,1846129472,2183533934,1091944,SRX4130196,SRS3344550,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92773,0.92439,0.09326,0.09299,0.71447,0.71877,0.4689,0.4801,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48323,SRR7223671,SRX4130195,SRS3344549,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,TrisCDPS3,,strain:Danio rerio|age:16 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of TrisCDPS treated zf: 5 day larvae,TrisCDPS3,TrisCDPS3,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,TrisCDPS3_1.fq.gz TrisCDPS3_2.fq.gz,fastq fastq,9172719000.0,30575730.0,TrisCDPS3 1.fq.gz,0:150 1:150,A:2507937903;C:2088057682;G:2095938157;T:2479548210;N:1237048,150,150,,,2507937903,2088057682,2095938157,2479548210,1237048,SRX4130195,SRS3344549,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92421,0.92576,0.09405,0.09332,0.71082,0.7148,0.47786,0.47144,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-12-31,Larval,Larval,Whole Organism,All anatomical structures
48324,SRR7223672,SRX4130194,SRS3344548,SRP149041,PRJNA473201,Danio rerio Genome sequencing,PRJNA473201,Other,To explore the potential mechanisms underlying wavy notochord caused in zebrafish embryos following exposure to polychlorinated diphenylsulfides,,,,,TrisCDPS2,,strain:Danio rerio|age:15 days|sex:pooled male and female|tissue:whole larvae|BioSampleModel:Model organism or animal,,,,,,,,,RNA Seq of TrisCDPS treated zf: 5 day larvae,TrisCDPS2,TrisCDPS2,TopHat FPKM FDR<0.05,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,Illumina HiSeq 4000,,SRP149041,,,TrisCDPS2_2.fq.gz TrisCDPS2_1.fq.gz,fastq fastq,7161083100.0,23870277.0,TrisCDPS2 1.fq.gz,0:150 1:150,A:1958680431;C:1628149492;G:1635229167;T:1937833061;N:1190949,150,150,,,1958680431,1628149492,1635229167,1937833061,1190949,SRX4130194,SRS3344548,SRA711726,University of Jinan|Environment,University of Jinan,2,0.92545,0.92016,0.09453,0.09357,0.70883,0.71401,0.47093,0.47799,150,150,B,B,biological fallback assumption,illumina,hiseq_era,unknown,random_priming,unknown,bulk,unknown,unknown,,China,2018-05-27,Larval,Larval,Whole Organism,All anatomical structures
49243,SRR7824324,SRX4675365,SRS3769144,SRP161624,PRJNA490559,GLDC KO ZEBRAFISH,PRJNA490559,Other,Differential Gene expression of 7 dpf larvae comparing +/+ and  /  GLDC KO larvae,,,,,WT,,strain:TL|dev stage:7 dpf|sex:not determined|tissue:whole embryo|genotype:gldc+/+|BioSampleModel:Model organism or animal,,,,,,,,,Danio Rerio 7 dpf GLDC+/+,GLDC WT,GLDC WT,Library preparation was performed using the Truseq RNA Illumina. 13 PCR cycles were required to amplify cDNA libraries. Libraries were quantified by Nanodrop and BioAnalyzer. All libraries were diluted to 10 nM and normalized with the Miseq SR50 v2. Libraries were pooled to equimolar concentration and multiplexed by 6 samples per lane.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,NextSeq 500,,SRP161624,,assembly:GRCz10 genome|loader:fastq load.py,._GLDC_whole7dpf_WT3_S8_L002_R2_001.fastq ._GLDC_whole7dpf_WT3_S8_L003_R1_001.fastq ._GLDC_whole7dpf_WT3_S8_L003_R2_001.fastq ._GLDC_whole7dpf_WT3_S8_L004_R2_001.fastq ._GLDC_whole7dpf_WT3_S8_L002_R1_001.fastq GLDC_whole7dpf_WT2_S7_L001_R2_001.fastq GLDC_whole7dpf_WT2_S7_L002_R1_001.fastq GLDC_whole7dpf_WT2_S7_L002_R2_001.fastq GLDC_whole7dpf_WT2_S7_L003_R1_001.fastq GLDC_whole7dpf_WT2_S7_L004_R1_001.fastq GLDC_whole7dpf_WT2_S7_L004_R2_001.fastq GLDC_whole7dpf_WT3_S8_L001_R1_001.fastq GLDC_whole7dpf_WT3_S8_L001_R2_001.fastq GLDC_whole7dpf_WT3_S8_L002_R1_001.fastq GLDC_whole7dpf_WT3_S8_L002_R2_001.fastq GLDC_whole7dpf_WT3_S8_L003_R1_001.fastq GLDC_whole7dpf_WT3_S8_L003_R2_001.fastq GLDC_whole7dpf_WT3_S8_L004_R2_001.fastq ._GLDC_whole7dpf_WT3_S8_L001_R2_001.fastq ._GLDC_whole7dpf_WT3_S8_L001_R1_001.fastq ._GLDC_whole7dpf_WT2_S7_L004_R2_001.fastq ._GLDC_whole7dpf_WT2_S7_L004_R1_001.fastq ._GLDC_whole7dpf_WT2_S7_L003_R1_001.fastq ._GLDC_whole7dpf_WT2_S7_L002_R2_001.fastq ._GLDC_whole7dpf_WT2_S7_L002_R1_001.fastq ._GLDC_whole7dpf_WT2_S7_L001_R2_001.fastq ._GLDC_whole7dpf_WT2_S7_L001_R1_001.fastq ._GLDC_whole7dpf_WT1_S6_L004_R2_001.fastq ._GLDC_whole7dpf_WT1_S6_L003_R2_001.fastq ._GLDC_whole7dpf_WT1_S6_L002_R1_001.fastq ._GLDC_whole7dpf_WT1_S6_L001_R2_001.fastq ._GLDC_whole7dpf_WT1_S6_L001_R1_001.fastq GLDC_whole7dpf_WT2_S7_L001_R1_001.fastq GLDC_whole7dpf_WT1_S6_L004_R2_001.fastq GLDC_whole7dpf_WT1_S6_L003_R2_001.fastq GLDC_whole7dpf_WT1_S6_L002_R1_001.fastq GLDC_whole7dpf_WT1_S6_L001_R2_001.fastq GLDC_whole7dpf_WT1_S6_L001_R1_001.fastq,fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq,450528.0,3744.0,WT.zip.tar,,A:109616;C:106322;G:107396;T:108223;N:18971,,,,,109616,106322,107396,108223,18971,SRX4675365,SRS3769144,SRA772670,CRCHUM|NEUROSCIENCES,CRCHUM,2,0.91448,0.93765,0.05757,0.05369,0.98117,0.98135,0.49734,0.48404,76,76,B,B,biological fallback assumption,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Canada,2021-02-25,Larval,Larval,Whole Organism,All anatomical structures
49244,SRR7824325,SRX4675364,SRS3769145,SRP161624,PRJNA490559,GLDC KO ZEBRAFISH,PRJNA490559,Other,Differential Gene expression of 7 dpf larvae comparing +/+ and  /  GLDC KO larvae,,,,,HM,,strain:TL|dev stage:7 dpf|sex:not determined|tissue:whole embryo|genotype:gldc / |BioSampleModel:Model organism or animal,,,,,,,,,Danio Rerio 7 dpf GLDC / ,GLDC HM,GLDC HM,Library preparation was performed using the Truseq RNA Illumina. 13 PCR cycles were required to amplify cDNA libraries. Libraries were quantified by Nanodrop and BioAnalyzer. All libraries were diluted to 10 nM and normalized with the Miseq SR50 v2. Libraries were pooled to equimolar concentration and multiplexed by 6 samples per lane.,,,RNA-Seq,TRANSCRIPTOMIC,PCR,PAIRED,ILLUMINA,NextSeq 500,,SRP161624,,assembly:GRCz10 genome|loader:fastq load.py,._GLDC_whole7dpf_HM1_S9_L001_R1_001.fastq ._GLDC_whole7dpf_HM1_S9_L001_R2_001.fastq ._GLDC_whole7dpf_HM1_S9_L002_R1_001.fastq ._GLDC_whole7dpf_HM1_S9_L002_R2_001.fastq ._GLDC_whole7dpf_HM1_S9_L003_R1_001.fastq ._GLDC_whole7dpf_HM1_S9_L003_R2_001.fastq ._GLDC_whole7dpf_HM1_S9_L004_R1_001.fastq ._GLDC_whole7dpf_HM1_S9_L004_R2_001.fastq ._GLDC_whole7dpf_HM2_S10_L001_R1_001.fastq ._GLDC_whole7dpf_HM2_S10_L001_R2_001.fastq ._GLDC_whole7dpf_HM2_S10_L002_R1_001.fastq ._GLDC_whole7dpf_HM2_S10_L002_R2_001.fastq ._GLDC_whole7dpf_HM2_S10_L003_R1_001.fastq ._GLDC_whole7dpf_HM2_S10_L003_R2_001.fastq ._GLDC_whole7dpf_HM2_S10_L004_R2_001.fastq ._GLDC_whole7dpf_HM3_S11_L001_R1_001.fastq ._GLDC_whole7dpf_HM3_S11_L001_R2_001.fastq ._GLDC_whole7dpf_HM3_S11_L002_R1_001.fastq ._GLDC_whole7dpf_HM3_S11_L003_R1_001.fastq ._GLDC_whole7dpf_HM3_S11_L003_R2_001.fastq ._GLDC_whole7dpf_HM3_S11_L004_R1_001.fastq GLDC_whole7dpf_HM1_S9_L001_R1_001.fastq GLDC_whole7dpf_HM1_S9_L001_R2_001.fastq GLDC_whole7dpf_HM1_S9_L002_R1_001.fastq GLDC_whole7dpf_HM1_S9_L002_R2_001.fastq GLDC_whole7dpf_HM1_S9_L003_R1_001.fastq GLDC_whole7dpf_HM1_S9_L003_R2_001.fastq GLDC_whole7dpf_HM1_S9_L004_R1_001.fastq GLDC_whole7dpf_HM1_S9_L004_R2_001.fastq GLDC_whole7dpf_HM2_S10_L001_R1_001.fastq GLDC_whole7dpf_HM2_S10_L001_R2_001.fastq GLDC_whole7dpf_HM2_S10_L002_R1_001.fastq GLDC_whole7dpf_HM2_S10_L002_R2_001.fastq GLDC_whole7dpf_HM2_S10_L003_R1_001.fastq GLDC_whole7dpf_HM2_S10_L003_R2_001.fastq GLDC_whole7dpf_HM2_S10_L004_R2_001.fastq GLDC_whole7dpf_HM3_S11_L001_R1_001.fastq GLDC_whole7dpf_HM3_S11_L001_R2_001.fastq GLDC_whole7dpf_HM3_S11_L002_R1_001.fastq GLDC_whole7dpf_HM3_S11_L003_R1_001.fastq GLDC_whole7dpf_HM3_S11_L003_R2_001.fastq GLDC_whole7dpf_HM3_S11_L004_R1_001.fastq,fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq fastq,497952.0,3744.0,HM.zip.tar,,A:121192;C:118254;G:118009;T:121857;N:18640,,,,,121192,118254,118009,121857,18640,SRX4675364,SRS3769145,SRA772670,CRCHUM|NEUROSCIENCES,CRCHUM,2,0.91422,0.92397,0.0656,0.06743,0.97528,0.97555,0.47174,0.47422,76,76,B,B,biological fallback assumption,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Canada,2021-02-25,Larval,Larval,Whole Organism,All anatomical structures
52216,SRR9164636,SRX5937422,SRS4850458,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,wt +/+ 3dpf 3,wt +/+ 3dpf 3,,filename:L1700046 Probe 20 plus plus 3dpf 1 2.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,wt +/+ 3dpf 3,wt +/+ 3dpf 3,wt +/+ 3dpf 3,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700046_Probe_20_plus_plus_3dpf_1_2.fq.gz,fastq,2506233674.0,16597574.0,L1700046 Probe 20 plus plus 3dpf 1 2.fq.gz,0:151 1:0,A:634000443;C:604069545;G:613398240;T:654463196;N:302250,151,0,,,634000443,604069545,613398240,654463196,302250,SRX5937422,SRS4850458,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.96178,,0.07984,,0.72125,,0.48053,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52217,SRR9164637,SRX5937421,SRS4850457,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,wt +/+ 3dpf 2,wt +/+ 3dpf 2,,filename:L1700052 Probe 14 plus plus 3dpf 4.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,wt +/+ 3dpf 2,wt +/+ 3dpf 2,wt +/+ 3dpf 2,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700052_Probe_14_plus_plus_3dpf_4.fq.gz,fastq,2552457794.0,16903694.0,L1700052 Probe 14 plus plus 3dpf 4.fq.gz,0:151 1:0,A:645631711;C:614227022;G:612129428;T:680168081;N:301552,151,0,,,645631711,614227022,612129428,680168081,301552,SRX5937421,SRS4850457,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.96269,,0.07747,,0.71871,,0.48604,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52218,SRR9164638,SRX5937420,SRS4850456,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,fgf3t24152  /  7dpf 2,fgf3t24152  /  7dpf 2,,filename:L1700048 Probe 22 minus minus 7dpf 4 5.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,fgf3t24152  /  7dpf 2,fgf3t24152  /  7dpf 2,fgf3t24152  /  7dpf 2,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700048_Probe_22_minus_minus_7dpf_4_5.fq.gz,fastq,2516535951.0,16665801.0,L1700048 Probe 22 minus minus 7dpf 4 5.fq.gz,0:151 1:0,A:660865986;C:587075382;G:595275252;T:673011628;N:307703,151,0,,,660865986,587075382,595275252,673011628,307703,SRX5937420,SRS4850456,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.9567,,0.10788,,0.7134,,0.51087,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52219,SRR9164639,SRX5937419,SRS4850455,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,fgf3t24152  /  7dpf 1,fgf3t24152  /  7dpf 1,,filename:L1700047 Probe 21 minus minus 7dpf 1 2.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,fgf3t24152  /  7dpf 1,fgf3t24152  /  7dpf 1,fgf3t24152  /  7dpf 1,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700047_Probe_21_minus_minus_7dpf_1_2.fq.gz,fastq,2466014673.0,16331223.0,L1700047 Probe 21 minus minus 7dpf 1 2.fq.gz,0:151 1:0,A:625570716;C:591147110;G:589476430;T:659526551;N:293866,151,0,,,625570716,591147110,589476430,659526551,293866,SRX5937419,SRS4850455,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.95779,,0.09881,,0.71206,,0.49427,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52220,SRR9164640,SRX5937418,SRS4850454,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,fgf3t24152  /  3dpf 2,fgf3t24152  /  3dpf 2,,filename:L1700045 Probe 19 minus minus 3dpf 3 4 5.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,fgf3t24152  /  3dpf 2,fgf3t24152  /  3dpf 2,fgf3t24152  /  3dpf 2,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700045_Probe_19_minus_minus_3dpf_3_4_5.fq.gz,fastq,2409258605.0,15955355.0,L1700045 Probe 19 minus minus 3dpf 3 4 5.fq.gz,0:151 1:0,A:608760544;C:578294028;G:574909172;T:647001344;N:293517,151,0,,,608760544,578294028,574909172,647001344,293517,SRX5937418,SRS4850454,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.96392,,0.07974,,0.71467,,0.47801,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52221,SRR9164641,SRX5937417,SRS4850453,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,fgf3t24152  /  3dpf 1,fgf3t24152  /  3dpf 1,,filename:L1700044 Probe 1 minus minus 3dpf 1.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,fgf3t24152  /  3dpf 1,fgf3t24152  /  3dpf 1,fgf3t24152  /  3dpf 1,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700044_Probe_1_minus_minus_3dpf_1.fq.gz,fastq,2424787596.0,16058196.0,L1700044 Probe 1 minus minus 3dpf 1.fq.gz,0:151 1:0,A:605667403;C:588658821;G:580998119;T:649175582;N:287671,151,0,,,605667403,588658821,580998119,649175582,287671,SRX5937417,SRS4850453,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.96678,,0.07043,,0.72151,,0.4886,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52222,SRR9164642,SRX5937416,SRS4850452,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,wt +/+ 7dpf 3,wt +/+ 7dpf 3,,filename:L1700055 Probe 16 plus plus 7dpf 4.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,wt +/+ 7dpf 3,wt +/+ 7dpf 3,wt +/+ 7dpf 3,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700055_Probe_16_plus_plus_7dpf_4.fq.gz,fastq,2406426147.0,15936597.0,L1700055 Probe 16 plus plus 7dpf 4.fq.gz,0:151 1:0,A:621628027;C:570510169;G:570560525;T:643440348;N:287078,151,0,,,621628027,570510169,570560525,643440348,287078,SRX5937416,SRS4850452,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.95873,,0.09322,,0.70849,,0.50116,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52223,SRR9164643,SRX5937415,SRS4850451,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,wt +/+ 7dpf 2,wt +/+ 7dpf 2,,filename:L1700054 Probe 11 plus plus 7dpf 2.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,wt +/+ 7dpf 2,wt +/+ 7dpf 2,wt +/+ 7dpf 2,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700054_Probe_11_plus_plus_7dpf_2.fq.gz,fastq,2388621586.0,15818686.0,L1700054 Probe 11 plus plus 7dpf 2.fq.gz,0:151 1:0,A:604867119;C:572969413;G:574552382;T:635946570;N:286102,151,0,,,604867119,572969413,574552382,635946570,286102,SRX5937415,SRS4850451,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.9601,,0.08858,,0.71226,,0.4818,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52224,SRR9164644,SRX5937414,SRS4850450,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,wt +/+ 3dpf 1,wt +/+ 3dpf 1,,filename:L1700051 Probe 6 plus plus 3dpf 3.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,wt +/+ 3dpf 1,wt +/+ 3dpf 1,wt +/+ 3dpf 1,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700051_Probe_6_plus_plus_3dpf_3.fq.gz,fastq,2516841877.0,16667827.0,L1700051 Probe 6 plus plus 3dpf 3.fq.gz,0:151 1:0,A:638504042;C:602279329;G:599178016;T:676575909;N:304581,151,0,,,638504042,602279329,599178016,676575909,304581,SRX5937414,SRS4850450,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.96561,,0.07463,,0.72054,,0.48315,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52225,SRR9164645,SRX5937413,SRS4850449,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,wt +/+ 7dpf 1,wt +/+ 7dpf 1,,filename:L1700049 Probe 23 plus plus 7dpf 1 3.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,wt +/+ 7dpf 1,wt +/+ 7dpf 1,wt +/+ 7dpf 1,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700049_Probe_23_plus_plus_7dpf_1_3.fq.gz,fastq,2811795311.0,18621161.0,L1700049 Probe 23 plus plus 7dpf 1 3.fq.gz,0:151 1:0,A:718804998;C:669270370;G:672469872;T:750915840;N:334231,151,0,,,718804998,669270370,672469872,750915840,334231,SRX5937413,SRS4850449,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.95734,,0.09739,,0.71256,,0.48704,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System
52226,SRR9164646,SRX5937412,SRS4850448,SRP199963,PRJNA541414,Danio rerio Raw sequence reads,PRJNA541414,Other,In most vertebrates  including zebrafish  the hypothalamicserotonergic cerebrospinal fluid contacting CSF c cells constitutea prominent population. In contrast to the hindbrain serotonergicneurons  little is known about the development and function of thesecells. Here  we identify fibroblast growth factor Fgf 3 as the main Fgfligand controlling the ontogeny of serotonergic CSF c cells. We showthat fgf3 positively regulates the number of serotonergic CSF c cells as well as a subset of dopaminergic and neuroendocrine cells in theposterior hypothalamus via control of proliferation and cell survival.Further  expression of the ETS domain transcription factor etv5b isdownregulated post fgf3 impairment. Previous findings identifiedetv5b as critical for the proliferation of serotonergic progenitors in thehypothalamus  and therefore we now suggest that Fgf3 acts via etv5bduring early development to ultimately control the number of matureserotonergic CSF c cells. Moreover  our analysis of the developinghypothalamic transcriptome shows that the expression of fgf3 isupregulated upon fgf3 loss of function  suggesting activation of a self compensatory mechanism. Together  these results highlight Fgf3 in anovel context as part of a signalling pathway of critical importance forhypothalamic development.,,,,fgf3t24152  /  7dpf 3,fgf3t24152  /  7dpf 3,,filename:L1700053 Probe 9 minus minus 7dpf 3.fq.gz|strain:Tuebingen|dev stage:embryo|sex:not determined|tissue:hypothalamus|BioSampleModel:Model organism or animal,,,,,,,,,fgf3t24152  /  7dpf 3,fgf3t24152  /  7dpf 3,fgf3t24152  /  7dpf 3,library preparation was performed according to the Illumina TruSeq stranded mRNA Samples Preparation Guide with 100 ng of input RNA and 15 PCR cycles,,,RNA-Seq,TRANSCRIPTOMIC,PCR,SINGLE,ILLUMINA,NextSeq 500,,SRP199963,,,L1700053_Probe_9_minus_minus_7dpf_3.fq.gz,fastq,2201563390.0,14579890.0,L1700053 Probe 9 minus minus 7dpf 3.fq.gz,0:151 1:0,A:559541557;C:523434389;G:527775051;T:590547674;N:264719,151,0,,,559541557,523434389,527775051,590547674,264719,SRX5937412,SRS4850448,SRA892447,University of Wuerzburg|Department for Physiological Chemistry,University of Wuerzburg,1,0.95732,,0.09772,,0.70678,,0.49199,,151,,B,,usable mapping rate,illumina,nextseq,unknown,random_priming,trueseq,bulk,unknown,unknown,,Germany,2019-05-31,Larval,Larval,Brain,Nervous System