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run_metadata

9 rows where experiment.platform = "BGISEQ", tissue_curation = "Head" and tissue_curation_coarse = "Nervous System"

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tissue_curation_coarse 1

  • Nervous System · 9 ✖

tissue_curation 1

  • Head · 9 ✖

technology 1

experiment.platform 1

  • BGISEQ · 9 ✖

experiment.library_strategy 1

experiment.library_source 1

experiment.library_selection 1

experiment.library_layout 1

devstage_curation_coarse 1

devstage_curation 1

Link rowid ▼ run.accession experiment.accession sample.accession study.accession bioproject study.title study.alias study.type study.abstract study.attributes study.PMIDs sample.description sample.title sample.alias sample.centername sample.attributes GEOsample.title GEOsample.dataprocessing GEOsample.source GEOsample.treatmentprotocol GEOsample.extractprotocol GEOsample.growthprotocol GEOsample.characteristics GEOsample.accession experiment.title experiment.alias experiment.library_name experiment.design_description experiment.library_construction_protocol experiment.attributes experiment.library_strategy experiment.library_source experiment.library_selection experiment.library_layout experiment.platform experiment.instrument_model experiment.spot_descriptor experiment.study_ref run.title run.attributes run.filename run.semantic_name run.total_bases run.total_spots run.alias run.read_lengths run.base_counts run.r1_length run.r2_length run.r3_length run.r4_length run.Acount run.Ccount run.Gcount run.Tcount run.Ncount run.experiment run.pool_member submission.accession submission.srasource submission.bioprojectsource seqdetective.n_mates seqdetective.mapping_rate.mate1 seqdetective.mapping_rate.mate2 seqdetective.nofeature_rate.mate1 seqdetective.nofeature_rate.mate2 seqdetective.sparsity.mate1 seqdetective.sparsity.mate2 seqdetective.pos_strand_rate.mate1 seqdetective.pos_strand_rate.mate2 seqdetective.readlen.mate1 seqdetective.readlen.mate2 seqdetective.judgement.mate1 seqdetective.judgement.mate2 seqdetective.judgement.reason platform_family instrument_generation read_bias selection_class prep_kit sc_or_bulk tech_class technology tech_variant submission.bioprojectsource.country earliest_date devstage_curation devstage_curation_coarse tissue_curation tissue_curation_coarse
57271 57271 SRR12577970 SRX9064853 SRS7314026 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ctrl 3 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 6'|BioSampleModel:Model organism or animal                 Ctrl 3 zebrafish Ctrl 3 zebrafish Ctrl 3 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ctrl_3_1.fq.gz fastq 1061227250.0 21224545.0 Ctrl 3 1.fq.gz 0:50 A:286099732;C:241244619;G:246876865;T:287006034;N:0 50       286099732 241244619 246876865 287006034 0 SRX9064853 SRS7314026 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94563   0.10453   0.70552   0.46655   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57272 57272 SRR12577971 SRX9064852 SRS7314025 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ctrl 2 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 5 prime|BioSampleModel:Model organism or animal                 Ctrl 2 zebrafish Ctrl 2 zebrafish Ctrl 2 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ctrl_2_1.fq.gz fastq 1058116700.0 21162334.0 Ctrl 2 1.fq.gz 0:50 A:287223905;C:238707750;G:244987559;T:287197486;N:0 50       287223905 238707750 244987559 287197486 0 SRX9064852 SRS7314025 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94534   0.11174   0.70104   0.47946   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57273 57273 SRR12577972 SRX9064851 SRS7314024 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ctrl 1 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 4'|BioSampleModel:Model organism or animal                 Ctrl 1 zebrafish Ctrl 1 zebrafish Ctrl 1 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ctrl_1_1.fq.gz fastq 1065919600.0 21318392.0 Ctrl 1 1.fq.gz 0:50 A:295920720;C:242146677;G:242962633;T:284889570;N:0 50       295920720 242146677 242962633 284889570 0 SRX9064851 SRS7314024 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94228   0.15007   0.68028   0.46845   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57274 57274 SRR12577973 SRX9064850 SRS7314023 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ator STS 3 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 3 prime|BioSampleModel:Model organism or animal                 Ator STS 3 zebrafish Ator STS 3 zebrafish Ator STS 3 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ator_STS_3_1.fq.gz fastq 1059717350.0 21194347.0 Ator STS 3 1.fq.gz 0:50 A:287279590;C:239708340;G:245740313;T:286989107;N:0 50       287279590 239708340 245740313 286989107 0 SRX9064850 SRS7314023 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94345   0.10458   0.69686   0.4755   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57275 57275 SRR12577974 SRX9064849 SRS7314022 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ator STS 2 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 2'|BioSampleModel:Model organism or animal                 Ator STS 2 zebrafish Ator STS 2 zebrafish Ator STS 2 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ator_STS_2_1.fq.gz fastq 1057950250.0 21159005.0 Ator STS 2 1.fq.gz 0:50 A:286256354;C:238832868;G:244078781;T:288782247;N:0 50       286256354 238832868 244078781 288782247 0 SRX9064849 SRS7314022 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94307   0.10974   0.69631   0.4703   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57276 57276 SRR12577975 SRX9064848 SRS7314021 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ator STS 1 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 1'|BioSampleModel:Model organism or animal                 Ator STS 1 zebrafish Ator STS 1 zebrafish Ator STS 1 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ator_STS_1_1.fq.gz fastq 1070136700.0 21402734.0 Ator STS 1 1.fq.gz 0:50 A:297601042;C:243837062;G:243583907;T:285114689;N:0 50       297601042 243837062 243583907 285114689 0 SRX9064848 SRS7314021 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94665   0.12219   0.67953   0.46393   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57277 57277 SRR12577976 SRX9064847 SRS7314020 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ator 3 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 3 prime|BioSampleModel:Model organism or animal                 Ator 3 zebrafish Ator 3 zebrafish Ator 3 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ator_3_1.fq.gz fastq 1058031900.0 21160638.0 Ator 3 1.fq.gz 0:50 A:285399527;C:239993172;G:245571467;T:287067734;N:0 50       285399527 239993172 245571467 287067734 0 SRX9064847 SRS7314020 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94536   0.11052   0.6957   0.48195   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57278 57278 SRR12577977 SRX9064846 SRS7314019 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ator 2 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 2'|BioSampleModel:Model organism or animal                 Ator 2 zebrafish Ator 2 zebrafish Ator 2 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ator_2_1.fq.gz fastq 1059618400.0 21192368.0 Ator 2 1.fq.gz 0:50 A:283429136;C:243023053;G:248904818;T:284261393;N:0 50       283429136 243023053 248904818 284261393 0 SRX9064846 SRS7314019 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94743   0.09493   0.70218   0.475   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System
57279 57279 SRR12577978 SRX9064845 SRS7314018 SRP279881 PRJNA612371 Danio rerio strain:TU Raw sequence reads PRJNA612371 Whole Genome Sequencing Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.         Ator 1 zebrafish   strain:TU|isolate:not collected|breed:not collected|cultivar:not collected|ecotype:not collected|age:2dpf|dev stage:not collected|sex:not applicable|tissue:head|geo loc name:China:Shanghai|sample type:model organism|replicate:replicate=biological replicate 1'|BioSampleModel:Model organism or animal                 Ator 1 zebrafish Ator 1 zebrafish Ator 1 zebrafish transcriptome     RNA-Seq TRANSCRIPTOMIC Oligo-dT SINGLE BGISEQ BGISEQ-500   SRP279881     Ator_1_1.fq.gz fastq 1075695950.0 21513919.0 Ator 1 1.fq.gz 0:50 A:297768036;C:244470267;G:243768925;T:289688722;N:0 50       297768036 244470267 243768925 289688722 0 SRX9064845 SRS7314018 SRA1120721 Shanghai University of Traditional Chinese Medicine|Longhua Hospital Shanghai University of Traditional Chinese Medicine 1 0.94468   0.13183   0.68363   0.46288   50   B   usable mapping rate bgi bgi unknown poly_a unknown bulk unknown unknown   China 2020-09-03 Hatching Embryo Head Nervous System

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CREATE TABLE run_metadata("run.accession" VARCHAR, "experiment.accession" VARCHAR, "sample.accession" VARCHAR, "study.accession" VARCHAR, bioproject VARCHAR, "study.title" VARCHAR, "study.alias" VARCHAR, "study.type" VARCHAR, "study.abstract" VARCHAR, "study.attributes" VARCHAR, "study.PMIDs" VARCHAR, "sample.description" VARCHAR, "sample.title" VARCHAR, "sample.alias" VARCHAR, "sample.centername" VARCHAR, "sample.attributes" VARCHAR, "GEOsample.title" VARCHAR, "GEOsample.dataprocessing" VARCHAR, "GEOsample.source" VARCHAR, "GEOsample.treatmentprotocol" VARCHAR, "GEOsample.extractprotocol" VARCHAR, "GEOsample.growthprotocol" VARCHAR, "GEOsample.characteristics" VARCHAR, "GEOsample.accession" VARCHAR, "experiment.title" VARCHAR, "experiment.alias" VARCHAR, "experiment.library_name" VARCHAR, "experiment.design_description" VARCHAR, "experiment.library_construction_protocol" VARCHAR, "experiment.attributes" VARCHAR, "experiment.library_strategy" VARCHAR, "experiment.library_source" VARCHAR, "experiment.library_selection" VARCHAR, "experiment.library_layout" VARCHAR, "experiment.platform" VARCHAR, "experiment.instrument_model" VARCHAR, "experiment.spot_descriptor" VARCHAR, "experiment.study_ref" VARCHAR, "run.title" VARCHAR, "run.attributes" VARCHAR, "run.filename" VARCHAR, "run.semantic_name" VARCHAR, "run.total_bases" DOUBLE, "run.total_spots" DOUBLE, "run.alias" VARCHAR, "run.read_lengths" VARCHAR, "run.base_counts" VARCHAR, "run.r1_length" BIGINT, "run.r2_length" BIGINT, "run.r3_length" BIGINT, "run.r4_length" BIGINT, "run.Acount" BIGINT, "run.Ccount" BIGINT, "run.Gcount" BIGINT, "run.Tcount" BIGINT, "run.Ncount" BIGINT, "run.experiment" VARCHAR, "run.pool_member" VARCHAR, "submission.accession" VARCHAR, "submission.srasource" VARCHAR, "submission.bioprojectsource" VARCHAR, "seqdetective.n_mates" BIGINT, "seqdetective.mapping_rate.mate1" DOUBLE, "seqdetective.mapping_rate.mate2" DOUBLE, "seqdetective.nofeature_rate.mate1" DOUBLE, "seqdetective.nofeature_rate.mate2" DOUBLE, "seqdetective.sparsity.mate1" DOUBLE, "seqdetective.sparsity.mate2" DOUBLE, "seqdetective.pos_strand_rate.mate1" DOUBLE, "seqdetective.pos_strand_rate.mate2" DOUBLE, "seqdetective.readlen.mate1" BIGINT, "seqdetective.readlen.mate2" BIGINT, "seqdetective.judgement.mate1" VARCHAR, "seqdetective.judgement.mate2" VARCHAR, "seqdetective.judgement.reason" VARCHAR, platform_family VARCHAR, instrument_generation VARCHAR, read_bias VARCHAR, selection_class VARCHAR, prep_kit VARCHAR, sc_or_bulk VARCHAR, tech_class VARCHAR, technology VARCHAR, tech_variant VARCHAR, "submission.bioprojectsource.country" VARCHAR, earliest_date DATE, devstage_curation VARCHAR, devstage_curation_coarse VARCHAR, tissue_curation VARCHAR, tissue_curation_coarse VARCHAR);;
CREATE INDEX idx_run_bioproject ON run_metadata(bioproject);;
CREATE INDEX idx_run_run_accession ON run_metadata("run.accession");;