metadata: run_metadata: 33 rows where experiment.library_selection = "other", experiment.library_source = "METATRANSCRIPTOMIC" and experiment.platform = "ILLUMINA"

33 rows where experiment.library_selection = "other", experiment.library_source = "METATRANSCRIPTOMIC" and experiment.platform = "ILLUMINA"

descending

Link	rowid ▼	run.accession	experiment.accession	sample.accession	study.accession	bioproject	study.title	study.alias	study.type	study.abstract	sample.description	sample.title	sample.alias	sample.attributes	experiment.title	experiment.alias	experiment.library_name	experiment.design_description	experiment.library_strategy	experiment.library_source	experiment.library_selection	experiment.library_layout	experiment.platform	experiment.instrument_model	experiment.study_ref	run.filename	run.semantic_name	run.total_bases	run.total_spots	run.alias	run.read_lengths	run.base_counts	run.r1_length	run.r2_length	run.Acount	run.Ccount	run.Gcount	run.Tcount	run.Ncount	run.experiment	run.pool_member	submission.accession	submission.srasource	submission.bioprojectsource	seqdetective.judgement.mate1	seqdetective.judgement.mate2	seqdetective.judgement.reason	platform_family	instrument_generation	read_bias	selection_class	prep_kit	sc_or_bulk	tech_class	technology	submission.bioprojectsource.country	earliest_date	devstage_curation	devstage_curation_coarse	tissue_curation	tissue_curation_coarse
30650	30650	SRR28054745	SRX23704460	SRS20534455	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1228	library ID:H 1\|title:High 1\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1228 rep1 1 URNA S72 L003 R1 001.fastq\|filename2:S21K1228 rep1 1 URNA S72 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	High 1	H 1	H 1	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1228_rep1_1_URNA_S72_L003_R1_001.fastq.gz S21K1228_rep1_1_URNA_S72_L003_R2_001.fastq.gz	fastq fastq	6506930400.0	21689768.0	S21K1228 rep1 1 URNA S72 L003 R1 001.fastq.gz	0:150 1:150	A:1750770382;C:1473474222;G:1551729505;T:1730941027;N:15264	150	150	1750770382	1473474222	1551729505	1730941027	15264	SRX23704460	SRS20534455	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30651	30651	SRR28054746	SRX23704459	SRS20534452	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1227	library ID:M 3\|title:Medium 3\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1227 rep1 1 URNA S71 L003 R1 001.fastq\|filename2:S21K1227 rep1 1 URNA S71 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Medium 3	M 3	M 3	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1227_rep1_1_URNA_S71_L003_R1_001.fastq.gz S21K1227_rep1_1_URNA_S71_L003_R2_001.fastq.gz	fastq fastq	6899268300.0	22997561.0	S21K1227 rep1 1 URNA S71 L003 R1 001.fastq.gz	0:150 1:150	A:1858425383;C:1565856426;G:1639602501;T:1835367744;N:16246	150	150	1858425383	1565856426	1639602501	1835367744	16246	SRX23704459	SRS20534452	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30652	30652	SRR28054747	SRX23704458	SRS20534453	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1226	library ID:M 2\|title:Medium 2\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1226 rep1 1 URNA S70 L003 R1 001.fastq\|filename2:S21K1226 rep1 1 URNA S70 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Medium 2	M 2	M 2	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1226_rep1_1_URNA_S70_L003_R1_001.fastq.gz S21K1226_rep1_1_URNA_S70_L003_R2_001.fastq.gz	fastq fastq	6310969500.0	21036565.0	S21K1226 rep1 1 URNA S70 L003 R1 001.fastq.gz	0:150 1:150	A:1688391347;C:1451351943;G:1503321023;T:1667755412;N:149775	150	150	1688391347	1451351943	1503321023	1667755412	149775	SRX23704458	SRS20534453	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30653	30653	SRR28054748	SRX23704457	SRS20534454	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1225	library ID:M 1\|title:Medium 1\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1225 rep1 1 URNA S69 L003 R1 001.fastq\|filename2:S21K1225 rep1 1 URNA S69 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Medium 1	M 1	M 1	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1225_rep1_1_URNA_S69_L003_R1_001.fastq.gz S21K1225_rep1_1_URNA_S69_L003_R2_001.fastq.gz	fastq fastq	8677007700.0	28923359.0	S21K1225 rep1 1 URNA S69 L003 R1 001.fastq.gz	0:150 1:150	A:2318840740;C:1999375306;G:2068690840;T:2290080340;N:20474	150	150	2318840740	1999375306	2068690840	2290080340	20474	SRX23704457	SRS20534454	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30654	30654	SRR28054749	SRX23704456	SRS20534450	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1224	library ID:L 3\|title:Low 3\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1224 rep1 1 URNA S68 L003 R1 001.fastq\|filename2:S21K1224 rep1 1 URNA S68 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Low 3	L 3	L 3	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1224_rep1_1_URNA_S68_L003_R1_001.fastq.gz S21K1224_rep1_1_URNA_S68_L003_R2_001.fastq.gz	fastq fastq	7160279400.0	23867598.0	S21K1224 rep1 1 URNA S68 L003 R1 001.fastq.gz	0:150 1:150	A:1893984011;C:1641393143;G:1753657602;T:1871228004;N:16640	150	150	1893984011	1641393143	1753657602	1871228004	16640	SRX23704456	SRS20534450	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30655	30655	SRR28054750	SRX23704455	SRS20534451	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1223	library ID:L 2\|title:Low 2\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1223 rep1 1 URNA S67 L003 R1 001.fastq\|filename2:S21K1223 rep1 1 URNA S67 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Low 2	L 2	L 2	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1223_rep1_1_URNA_S67_L003_R1_001.fastq.gz S21K1223_rep1_1_URNA_S67_L003_R2_001.fastq.gz	fastq fastq	6779124000.0	22597080.0	S21K1223 rep1 1 URNA S67 L003 R1 001.fastq.gz	0:150 1:150	A:1804338053;C:1556291420;G:1636850001;T:1781628665;N:15861	150	150	1804338053	1556291420	1636850001	1781628665	15861	SRX23704455	SRS20534451	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30656	30656	SRR28054751	SRX23704454	SRS20534449	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1222	library ID:L 1\|title:Low 1\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1222 rep1 1 URNA S66 L003 R1 001.fastq\|filename2:S21K1222 rep1 1 URNA S66 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Low 1	L 1	L 1	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1222_rep1_1_URNA_S66_L003_R1_001.fastq.gz S21K1222_rep1_1_URNA_S66_L003_R2_001.fastq.gz	fastq fastq	7484014500.0	24946715.0	S21K1222 rep1 1 URNA S66 L003 R1 001.fastq.gz	0:150 1:150	A:1895991723;C:1633895559;G:2095064183;T:1859045639;N:17396	150	150	1895991723	1633895559	2095064183	1859045639	17396	SRX23704454	SRS20534449	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30657	30657	SRR28054752	SRX23704453	SRS20534447	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1221	library ID:C 3\|title:Control 3\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1221 rep1 1 URNA S65 L003 R1 001.fastq\|filename2:S21K1221 rep1 1 URNA S65 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Control 3	C 3	C 3	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1221_rep1_1_URNA_S65_L003_R1_001.fastq.gz S21K1221_rep1_1_URNA_S65_L003_R2_001.fastq.gz	fastq fastq	6562506000.0	21875020.0	S21K1221 rep1 1 URNA S65 L003 R1 001.fastq.gz	0:150 1:150	A:1753018331;C:1507753283;G:1569109292;T:1732610076;N:15018	150	150	1753018331	1507753283	1569109292	1732610076	15018	SRX23704453	SRS20534447	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30658	30658	SRR28054753	SRX23704452	SRS20534448	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1230	library ID:H 3\|title:High 3\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1230 rep1 1 URNA S74 L003 R1 001.fastq\|filename2:S21K1230 rep1 1 URNA S74 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	High 3	H 3	H 3	missing	RNA-Seq	METATRANSCRIPTOMIC	other	SINGLE	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1230_rep1_1_URNA_S74_L003_R1_001.fastq.gz S21K1230_rep1_1_URNA_S74_L003_R2_001.fastq.gz	fastq fastq	6117817800.0	20392726.0	S21K1230 rep1 1 URNA S74 L003 R1 001.fastq.gz	0:150 1:150	A:1635728688;C:1405168032;G:1464072107;T:1612834762;N:14211	150	150	1635728688	1405168032	1464072107	1612834762	14211	SRX23704452	SRS20534448	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30659	30659	SRR28054754	SRX23704451	SRS20534446	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1229	library ID:H 2\|title:High 2\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1229 rep1 1 URNA S73 L003 R1 001.fastq\|filename2:S21K1229 rep1 1 URNA S73 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	High 2	H 2	H 2	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1229_rep1_1_URNA_S73_L003_R1_001.fastq.gz S21K1229_rep1_1_URNA_S73_L003_R2_001.fastq.gz	fastq fastq	7164803100.0	23882677.0	S21K1229 rep1 1 URNA S73 L003 R1 001.fastq.gz	0:150 1:150	A:1920286881;C:1649856655;G:1697032084;T:1897610671;N:16809	150	150	1920286881	1649856655	1697032084	1897610671	16809	SRX23704451	SRS20534446	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30660	30660	SRR28054755	SRX23704450	SRS20534445	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1220	library ID:C 2\|title:Control 2\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1220 rep1 1 URNA S64 L003 R1 001.fastq\|filename2:S21K1220 rep1 1 URNA S64 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Control 2	C 2	C 2	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1220_rep1_1_URNA_S64_L003_R1_001.fastq.gz S21K1220_rep1_1_URNA_S64_L003_R2_001.fastq.gz	fastq fastq	6790504800.0	22635016.0	S21K1220 rep1 1 URNA S64 L003 R1 001.fastq.gz	0:150 1:150	A:1784553430;C:1593393319;G:1650087761;T:1762454671;N:15619	150	150	1784553430	1593393319	1650087761	1762454671	15619	SRX23704450	SRS20534445	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
30661	30661	SRR28054756	SRX23704449	SRS20534444	SRP491086	PRJNA1078753	Integrated mRNA and miRNA sequencing analyses unveil the underlying mechanism of tobacco pollutant induced developmental toxicity in zebrafish embryos	PRJNA1078753	Other	Tobacco pollutants are prevalent in the environment leading to inadvertent exposure of pregnant females. Studies of these pollutants' toxic effects on development have not fully elucidated the potential underlying mechanisms. Therefore in this study we aim at investigate the developmental toxicity induced by cigarette smoke extract CSE at concentrations of 0.25% 1% and 2.5% using a zebrafish embryo toxicity test and integrated transcriptomic analysis of microRNA miRNA and messenger RNA mRNA. The findings revealed that CSE caused developmental toxicity including increased mortality and decreased incubation rate in a dose dependent manner. Moreover CSE induced malformations and apoptosis specifically in the head and heart of zebrafish larvae. We used mRNA and miRNA sequencing analyses to compare changes in the expression of genes and miRNAs in zebrafish larvae. The bioinformatics analysis indicates that the mechanism underlying CSE induced developmental toxicity was associated with genetic repair impairment apoptosis disorder and lipid metabolism disturbance. The enrichment analysis and RT qPCR show that the ctsba gene plays a crucial function in embryo developmental apoptosis and the fads2 gene mainly regulates lipid metabolic toxicity. The results of this study improve the understanding of CSE induced developmental toxicity in zebrafish embryos and contribute insights into the formulation of novel preventive strategies against tobacco pollutants during early embryonic development.			S21K1219	library ID:C 1\|title:Control 1\|library strategy:OTHER\|library source:METATRANSCRIPTIOMIC\|library selection:other\|library layout:paired\|platform:ILLUMINA\|instrument model:RNA seq\|filetype:fastq\|filename:S21K1219 rep1 1 URNA S63 L003 R1 001.fastq\|filename2:S21K1219 rep1 1 URNA S63 L003 R2 001.fastq\|host:missing\|isolation source:missing\|collection date:missing\|geographic location:missing\|latitude and longitude:missing\|age:missing\|breed:missing\|cultivar:missing\|dev stage:missing\|ecotype:missing\|isolate:missing\|sex:missing\|strain:missing\|tissue:missing\|BioSampleModel:Model organism or animal	Control 1	C 1	C 1	missing	RNA-Seq	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP491086	S21K1219_rep1_1_URNA_S63_L003_R1_001.fastq.gz S21K1219_rep1_1_URNA_S63_L003_R2_001.fastq.gz	fastq fastq	7498264200.0	24994214.0	S21K1219 rep1 1 URNA S63 L003 R1 001.fastq.gz	0:150 1:150	A:2002773492;C:1716996682;G:1800329295;T:1978147319;N:17412	150	150	2002773492	1716996682	1800329295	1978147319	17412	SRX23704449	SRS20534444	SRA1806456	The Second Affiliated Hospital of Shantou University Medical College\|Department of Burns and Plastic Surgery	The Second Affiliated Hospital of Shantou University Medical College	B	B	biological fallback assumption	illumina	novaseq_era	unknown	small_rna	unknown	bulk	unknown	unknown	China	2024-02-22	Undetermined	Multi-stage	Undetermined	Undetermined
32508	32508	SRR29290248	SRX24807391	SRS21522263	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 1	liver transcriptome	L4 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 09\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 14\|experiment description:Exposure to 80 100 mesh tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L4 1	L4 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TMFA6-7L.R1.fq.gz TMFA6-7L.R2.fq.gz	fastq fastq	5892231600.0	19640772.0	TMFA6 7L.R1.fq.gz	0:150 1:150	A:1471743634;C:1450664701;G:1502453832;T:1466956960;N:412473	150	150	1471743634	1450664701	1502453832	1466956960	412473	SRX24807391	SRS21522263	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32509	32509	SRR29290249	SRX24807390	SRS21522262	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 3	liver transcriptome	L3 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 23\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 13\|experiment description:Exposed to tire wear particles above 120 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L3 3	L3 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TLSC-5L.R1.fq.gz TLSC-5L.R2.fq.gz	fastq fastq	6269295000.0	20897650.0	TLSC 5L.R1.fq.gz	0:150 1:150	A:1541736942;C:1578334203;G:1620160556;T:1528907120;N:156179	150	150	1541736942	1578334203	1620160556	1528907120	156179	SRX24807390	SRS21522262	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32510	32510	SRR29290250	SRX24807389	SRS21522261	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 2	liver transcriptome	L3 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 23\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 12\|experiment description:Exposed to tire wear particles above 120 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L3 2	L3 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TLSB-3L.R1.fq.gz TLSB-3L.R2.fq.gz	fastq fastq	6206673000.0	20688910.0	TLSB 3L.R1.fq.gz	0:150 1:150	A:1592564670;C:1487253074;G:1531600191;T:1595004475;N:250590	150	150	1592564670	1487253074	1531600191	1595004475	250590	SRX24807389	SRS21522261	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32511	32511	SRR29290251	SRX24807388	SRS21522260	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 1	liver transcriptome	L3 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 23\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 11\|experiment description:Exposed to tire wear particles above 120 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L3 1	L3 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TLSA-1L.R1.fq.gz TLSA-1L.R2.fq.gz	fastq fastq	6188928300.0	20629761.0	TLSA 1L.R1.fq.gz	0:150 1:150	A:1584479312;C:1464260894;G:1549296685;T:1590644766;N:246643	150	150	1584479312	1464260894	1549296685	1590644766	246643	SRX24807388	SRS21522260	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32512	32512	SRR29290252	SRX24807387	SRS21522259	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 3	liver transcriptome	L2 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 08\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 16\|experiment description:Exposed to 120 or above tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L2 3	L2 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TLFC1-3L.R1.fq.gz TLFC1-3L.R2.fq.gz	fastq fastq	6367070400.0	21223568.0	TLFC1 3L.R1.fq.gz	0:150 1:150	A:1579430230;C:1587605262;G:1613210542;T:1586578782;N:245584	150	150	1579430230	1587605262	1613210542	1586578782	245584	SRX24807387	SRS21522259	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32513	32513	SRR29290253	SRX24807386	SRS21522258	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 2	liver transcriptome	L2 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 08\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 15\|experiment description:Exposed to 120 or above tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L2 2	L2 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TLFB1-3L.R1.fq.gz TLFB1-3L.R2.fq.gz	fastq fastq	6996653100.0	23322177.0	TLFB1 3L.R1.fq.gz	0:150 1:150	A:1803878205;C:1678057588;G:1715367000;T:1799170285;N:180022	150	150	1803878205	1678057588	1715367000	1799170285	180022	SRX24807386	SRS21522258	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32514	32514	SRR29290254	SRX24807385	SRS21522257	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 1	liver transcriptome	L2 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 08\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 14\|experiment description:Exposed to 120 or above tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L2 1	L2 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TLFA6-7L.R1.fq.gz TLFA6-7L.R2.fq.gz	fastq fastq	6109509300.0	20365031.0	TLFA6 7L.R1.fq.gz	0:150 1:150	A:1525902154;C:1507317327;G:1549698641;T:1526193716;N:397462	150	150	1525902154	1507317327	1549698641	1526193716	397462	SRX24807385	SRS21522257	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32515	32515	SRR29290255	SRX24807384	SRS21522256	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 3	liver transcriptome	L7 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 25\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 13\|experiment description:Exposed to tire wear particles 40 60 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L7 3	L7 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TSSC-5L.R1.fq.gz TSSC-5L.R2.fq.gz	fastq fastq	6846271200.0	22820904.0	TSSC 5L.R1.fq.gz	0:150 1:150	A:1704275603;C:1639794530;G:1792628691;T:1709317043;N:255333	150	150	1704275603	1639794530	1792628691	1709317043	255333	SRX24807384	SRS21522256	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32516	32516	SRR29290256	SRX24807383	SRS21522255	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	Control parallel 3	liver transcriptome	L1 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 11\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 13\|experiment description:Sample from control group\|BioSampleModel:Model organism or animal	Zebrafish liver	L1 3	L1 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	FCFC1-3L.R1.fq.gz FCFC1-3L.R2.fq.gz	fastq fastq	6360438000.0	21201460.0	FCFC1 3L.R1.fq.gz	0:150 1:150	A:1591177652;C:1544470038;G:1615057708;T:1609485267;N:247335	150	150	1591177652	1544470038	1615057708	1609485267	247335	SRX24807383	SRS21522255	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32517	32517	SRR29290257	SRX24807382	SRS21522254	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 2	liver transcriptome	L7 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 25\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 12\|experiment description:Exposed to tire wear particles 40 60 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L7 2	L7 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TSSB-3L.R1.fq.gz TSSB-3L.R2.fq.gz	fastq fastq	6285285600.0	20950952.0	TSSB 3L.R1.fq.gz	0:150 1:150	A:1584093051;C:1516123512;G:1599998121;T:1584824364;N:246552	150	150	1584093051	1516123512	1599998121	1584824364	246552	SRX24807382	SRS21522254	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32518	32518	SRR29290258	SRX24807381	SRS21522253	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 1	liver transcriptome	L7 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 25\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 11\|experiment description:Exposed to tire wear particles 40 60 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L7 1	L7 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TSSA-1L.R1.fq.gz TSSA-1L.R2.fq.gz	fastq fastq	6078740100.0	20262467.0	TSSA 1L.R1.fq.gz	0:150 1:150	A:1530149533;C:1486474895;G:1528868563;T:1533006599;N:240510	150	150	1530149533	1486474895	1528868563	1533006599	240510	SRX24807381	SRS21522253	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32519	32519	SRR29290259	SRX24807380	SRS21522252	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 3	liver transcriptome	L6 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 10\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 16\|experiment description:Exposure to 40 60 mesh tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L6 3	L6 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TSFC1-3L.R1.fq.gz TSFC1-3L.R2.fq.gz	fastq fastq	6857466600.0	22858222.0	TSFC1 3L.R1.fq.gz	0:150 1:150	A:1755136176;C:1642995302;G:1688825155;T:1770233592;N:276375	150	150	1755136176	1642995302	1688825155	1770233592	276375	SRX24807380	SRS21522252	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32520	32520	SRR29290260	SRX24807379	SRS21522251	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 2	liver transcriptome	L6 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 10\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 15\|experiment description:Exposure to 40 60 mesh tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L6 2	L6 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TSFB1-3L.R1.fq.gz TSFB1-3L.R2.fq.gz	fastq fastq	7250329800.0	24167766.0	TSFB1 3L.R1.fq.gz	0:150 1:150	A:1825803037;C:1766132142;G:1813762639;T:1844348502;N:283480	150	150	1825803037	1766132142	1813762639	1844348502	283480	SRX24807379	SRS21522251	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32521	32521	SRR29290261	SRX24807378	SRS21522250	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 1	liver transcriptome	L6 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 10\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 14\|experiment description:Exposure to 40 60 mesh tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L6 1	L6 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TSFA1-3L.R1.fq.gz TSFA1-3L.R2.fq.gz	fastq fastq	6257752800.0	20859176.0	TSFA1 3L.R1.fq.gz	0:150 1:150	A:1588621972;C:1490176001;G:1573465475;T:1605244426;N:244926	150	150	1588621972	1490176001	1573465475	1605244426	244926	SRX24807378	SRS21522250	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32522	32522	SRR29290262	SRX24807377	SRS21522249	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 3	liver transcriptome	L5 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 24\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 13\|experiment description:Exposed to tire wear particles 80 100 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L5 3	L5 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TMSC-5L.R1.fq.gz TMSC-5L.R2.fq.gz	fastq fastq	6227549100.0	20758497.0	TMSC 5L.R1.fq.gz	0:150 1:150	A:1601663321;C:1467885504;G:1549957271;T:1607796578;N:246426	150	150	1601663321	1467885504	1549957271	1607796578	246426	SRX24807377	SRS21522249	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32523	32523	SRR29290263	SRX24807376	SRS21522248	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 2	liver transcriptome	L5 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 24\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 12\|experiment description:Exposed to tire wear particles 80 100 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L5 2	L5 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TMSB-3L.R1.fq.gz TMSB-3L.R2.fq.gz	fastq fastq	5889087600.0	19630292.0	TMSB 3L.R1.fq.gz	0:150 1:150	A:1507527640;C:1395223794;G:1475557797;T:1510549619;N:228750	150	150	1507527640	1395223794	1475557797	1510549619	228750	SRX24807376	SRS21522248	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32524	32524	SRR29290264	SRX24807375	SRS21522247	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	30 days experimental group parallel 1	liver transcriptome	L5 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 24\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 11\|experiment description:Exposed to tire wear particles 80 100 mesh excretion for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L5 1	L5 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TMSA-1L.R1.fq.gz TMSA-1L.R2.fq.gz	fastq fastq	6438780300.0	21462601.0	TMSA 1L.R1.fq.gz	0:150 1:150	A:1651115385;C:1542448300;G:1589631411;T:1655336061;N:249143	150	150	1651115385	1542448300	1589631411	1655336061	249143	SRX24807375	SRS21522247	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32525	32525	SRR29290265	SRX24807374	SRS21522246	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 3	liver transcriptome	L4 3	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 09\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 16\|experiment description:Exposure to 80 100 mesh tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L4 3	L4 3	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TMFC1-3L.R1.fq.gz TMFC1-3L.R2.fq.gz	fastq fastq	6083883300.0	20279611.0	TMFC1 3L.R1.fq.gz	0:150 1:150	A:1510698562;C:1511134044;G:1540128451;T:1521679717;N:242526	150	150	1510698562	1511134044	1540128451	1521679717	242526	SRX24807374	SRS21522246	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32526	32526	SRR29290266	SRX24807373	SRS21522245	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	15 days experimental group parallel 2	liver transcriptome	L4 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 09\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 15\|experiment description:Exposure to 80 100 mesh tire wear particles for 15 days\|BioSampleModel:Model organism or animal	Zebrafish liver	L4 2	L4 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	TMFB1-3L.R1.fq.gz TMFB1-3L.R2.fq.gz	fastq fastq	5908013700.0	19693379.0	TMFB1 3L.R1.fq.gz	0:150 1:150	A:1507137134;C:1415511620;G:1463261753;T:1521838130;N:265063	150	150	1507137134	1415511620	1463261753	1521838130	265063	SRX24807373	SRS21522245	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32527	32527	SRR29290267	SRX24807372	SRS21522244	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	Control parallel 2	liver transcriptome	L1 2	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 11\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 12\|experiment description:Sample from control group\|BioSampleModel:Model organism or animal	Zebrafish liver	L1 2	L1 2	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	FCFB1-3L.R1.fq.gz FCFB1-3L.R2.fq.gz	fastq fastq	6637856700.0	22126189.0	FCFB1 3L.R1.fq.gz	0:150 1:150	A:1714779556;C:1575842801;G:1628771136;T:1718209685;N:253522	150	150	1714779556	1575842801	1628771136	1718209685	253522	SRX24807372	SRS21522244	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System
32528	32528	SRR29290268	SRX24807371	SRS21522243	SRP511901	PRJNA1120203	Study of liver transcriptome in zebrafish May 29 '24	PRJNA1120203	Other	Liver of the transcriptome data from zebrafish exposed to small car tire wear particles	Control parallel 1	liver transcriptome	L1 1	strain:not applicable\|isolate:not applicable\|breed:zebrafish\|cultivar:not applicable\|ecotype:not applicable\|age:3 month\|dev stage:3 month\|collection date:2023 08 11\|geo loc name:China\|sex:not collected\|tissue:liver\|birth date:2023 05 11\|experiment description:Sample from control group\|BioSampleModel:Model organism or animal	Zebrafish liver	L1 1	L1 1	Total RNA was extracted from the zebrafish liver tissue using a commercial RNA extraction kit following the manufacturer's instructions.The prepared library was sequenced on an Illumina HiSeq platform generating paired end reads.	OTHER	METATRANSCRIPTOMIC	other	PAIRED	ILLUMINA	Illumina NovaSeq 6000	SRP511901	FCFA1-3L.R1.fq.gz FCFA1-3L.R2.fq.gz	fastq fastq	7360809900.0	24536033.0	FCFA1 3L.R1.fq.gz	0:150 1:150	A:1885247052;C:1777296186;G:1818891778;T:1879185198;N:189686	150	150	1885247052	1777296186	1818891778	1879185198	189686	SRX24807371	SRS21522243	SRA1889615	Qingdao University of Science and technology\|College of marine science and biological engineeri	Qingdao University of Science and technology	B	B	biological fallback assumption	illumina	novaseq_era	unknown	other	unknown	bulk	unknown	unknown	China	2024-06-05	Adult	Adult	Liver	Liver and Biliary System

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CREATE TABLE run_metadata("run.accession" VARCHAR, "experiment.accession" VARCHAR, "sample.accession" VARCHAR, "study.accession" VARCHAR, bioproject VARCHAR, "study.title" VARCHAR, "study.alias" VARCHAR, "study.type" VARCHAR, "study.abstract" VARCHAR, "study.attributes" VARCHAR, "study.PMIDs" VARCHAR, "sample.description" VARCHAR, "sample.title" VARCHAR, "sample.alias" VARCHAR, "sample.centername" VARCHAR, "sample.attributes" VARCHAR, "GEOsample.title" VARCHAR, "GEOsample.dataprocessing" VARCHAR, "GEOsample.source" VARCHAR, "GEOsample.treatmentprotocol" VARCHAR, "GEOsample.extractprotocol" VARCHAR, "GEOsample.growthprotocol" VARCHAR, "GEOsample.characteristics" VARCHAR, "GEOsample.accession" VARCHAR, "experiment.title" VARCHAR, "experiment.alias" VARCHAR, "experiment.library_name" VARCHAR, "experiment.design_description" VARCHAR, "experiment.library_construction_protocol" VARCHAR, "experiment.attributes" VARCHAR, "experiment.library_strategy" VARCHAR, "experiment.library_source" VARCHAR, "experiment.library_selection" VARCHAR, "experiment.library_layout" VARCHAR, "experiment.platform" VARCHAR, "experiment.instrument_model" VARCHAR, "experiment.spot_descriptor" VARCHAR, "experiment.study_ref" VARCHAR, "run.title" VARCHAR, "run.attributes" VARCHAR, "run.filename" VARCHAR, "run.semantic_name" VARCHAR, "run.total_bases" DOUBLE, "run.total_spots" DOUBLE, "run.alias" VARCHAR, "run.read_lengths" VARCHAR, "run.base_counts" VARCHAR, "run.r1_length" BIGINT, "run.r2_length" BIGINT, "run.r3_length" BIGINT, "run.r4_length" BIGINT, "run.Acount" BIGINT, "run.Ccount" BIGINT, "run.Gcount" BIGINT, "run.Tcount" BIGINT, "run.Ncount" BIGINT, "run.experiment" VARCHAR, "run.pool_member" VARCHAR, "submission.accession" VARCHAR, "submission.srasource" VARCHAR, "submission.bioprojectsource" VARCHAR, "seqdetective.n_mates" BIGINT, "seqdetective.mapping_rate.mate1" DOUBLE, "seqdetective.mapping_rate.mate2" DOUBLE, "seqdetective.nofeature_rate.mate1" DOUBLE, "seqdetective.nofeature_rate.mate2" DOUBLE, "seqdetective.sparsity.mate1" DOUBLE, "seqdetective.sparsity.mate2" DOUBLE, "seqdetective.pos_strand_rate.mate1" DOUBLE, "seqdetective.pos_strand_rate.mate2" DOUBLE, "seqdetective.readlen.mate1" BIGINT, "seqdetective.readlen.mate2" BIGINT, "seqdetective.judgement.mate1" VARCHAR, "seqdetective.judgement.mate2" VARCHAR, "seqdetective.judgement.reason" VARCHAR, platform_family VARCHAR, instrument_generation VARCHAR, read_bias VARCHAR, selection_class VARCHAR, prep_kit VARCHAR, sc_or_bulk VARCHAR, tech_class VARCHAR, technology VARCHAR, tech_variant VARCHAR, "submission.bioprojectsource.country" VARCHAR, earliest_date DATE, devstage_curation VARCHAR, devstage_curation_coarse VARCHAR, tissue_curation VARCHAR, tissue_curation_coarse VARCHAR);;
CREATE INDEX idx_run_bioproject ON run_metadata(bioproject);;
CREATE INDEX idx_run_run_accession ON run_metadata("run.accession");;