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66 rows where experiment.library_selection = "PolyA", experiment.library_source = "TRANSCRIPTOMIC" and tissue_curation_coarse = "Renal System"

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experiment.library_layout 2

devstage_curation_coarse 2

devstage_curation 2

tissue_curation_coarse 1

  • Renal System · 66 ✖

tissue_curation 1

technology 1

experiment.platform 1

experiment.library_strategy 1

experiment.library_source 1

  • TRANSCRIPTOMIC · 66 ✖

experiment.library_selection 1

  • PolyA · 66 ✖
Link rowid ▼ run.accession experiment.accession sample.accession study.accession bioproject study.title study.alias study.type study.abstract study.attributes study.PMIDs sample.description sample.title sample.alias sample.centername sample.attributes GEOsample.title GEOsample.dataprocessing GEOsample.source GEOsample.treatmentprotocol GEOsample.extractprotocol GEOsample.growthprotocol GEOsample.characteristics GEOsample.accession experiment.title experiment.alias experiment.library_name experiment.design_description experiment.library_construction_protocol experiment.attributes experiment.library_strategy experiment.library_source experiment.library_selection experiment.library_layout experiment.platform experiment.instrument_model experiment.spot_descriptor experiment.study_ref run.title run.attributes run.filename run.semantic_name run.total_bases run.total_spots run.alias run.read_lengths run.base_counts run.r1_length run.r2_length run.r3_length run.r4_length run.Acount run.Ccount run.Gcount run.Tcount run.Ncount run.experiment run.pool_member submission.accession submission.srasource submission.bioprojectsource seqdetective.n_mates seqdetective.mapping_rate.mate1 seqdetective.mapping_rate.mate2 seqdetective.nofeature_rate.mate1 seqdetective.nofeature_rate.mate2 seqdetective.sparsity.mate1 seqdetective.sparsity.mate2 seqdetective.pos_strand_rate.mate1 seqdetective.pos_strand_rate.mate2 seqdetective.readlen.mate1 seqdetective.readlen.mate2 seqdetective.judgement.mate1 seqdetective.judgement.mate2 seqdetective.judgement.reason platform_family instrument_generation read_bias selection_class prep_kit sc_or_bulk tech_class technology tech_variant submission.bioprojectsource.country earliest_date devstage_curation devstage_curation_coarse tissue_curation tissue_curation_coarse
48941 48941 SRR7535399 SRX4403259 SRS3557748 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample43 F3HFL6   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3HFL6 L43 F3HFL6 L43 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3HFL6.fastq.gz fastq 3513906206.0 41769622.0 F3HFL6.fastq.gz 0:84.13 1:0 A:977114573;C:787720805;G:749651347;T:999364818;N:54663 84 0     977114573 787720805 749651347 999364818 54663 SRX4403259 SRS3557748 SRA741696 Gov of Canada Gov of Canada 1 0.95671   0.06506   0.78228   0.56305   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48942 48942 SRR7535400 SRX4403258 SRS3557747 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample41 F3HFL4   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3HFL4 L41 F3HFL4 L41 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3HFL4.fastq.gz fastq 1925799513.0 22885356.0 F3HFL4.fastq.gz 0:84.15 1:0 A:524298249;C:430610288;G:398055851;T:572803437;N:31688 84 0     524298249 430610288 398055851 572803437 31688 SRX4403258 SRS3557747 SRA741696 Gov of Canada Gov of Canada 1 0.93737   0.10113   0.81022   0.55692   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48943 48943 SRR7535401 SRX4403257 SRS3557746 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample42 F3HFL5   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3HFL5 L42 F3HFL5 L42 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3HFL5.fastq.gz fastq 2861742645.0 33977477.0 F3HFL5.fastq.gz 0:84.22 1:0 A:771306767;C:644570838;G:600324085;T:845486554;N:54401 84 0     771306767 644570838 600324085 845486554 54401 SRX4403257 SRS3557746 SRA741696 Gov of Canada Gov of Canada 1 0.95145   0.08188   0.78084   0.53906   82   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-07-18 Adult Adult Kidney Renal System
48944 48944 SRR7535402 SRX4403256 SRS3557745 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample21 F0HFL8   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL8 L21 F0HFL8 L21 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL8.fastq.gz fastq 3270195567.0 43558704.0 F0HFL8.fastq.gz 0:75.08 1:0 A:931015183;C:710121529;G:674934313;T:954020799;N:103743 75 0     931015183 710121529 674934313 954020799 103743 SRX4403256 SRS3557745 SRA741696 Gov of Canada Gov of Canada 1 0.94496   0.07696   0.74931   0.55469   76   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48945 48945 SRR7535403 SRX4403255 SRS3557744 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample22 F3CTR1   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR1 L22 F3CTR1 L22 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR1.fastq.gz fastq 2224836049.0 29606943.0 F3CTR1.fastq.gz 0:75.15 1:0 A:610515696;C:506550058;G:471139873;T:636560130;N:70292 75 0     610515696 506550058 471139873 636560130 70292 SRX4403255 SRS3557744 SRA741696 Gov of Canada Gov of Canada 1 0.95447   0.0754   0.78066   0.54856   75   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48946 48946 SRR7535404 SRX4403254 SRS3557743 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample23 F3CTR2   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR2 L23 F3CTR2 L23 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR2.fastq.gz fastq 3106167820.0 36871227.0 F3CTR2.fastq.gz 0:84.24 1:0 A:844192333;C:713285812;G:657110592;T:891518698;N:60385 84 0     844192333 713285812 657110592 891518698 60385 SRX4403254 SRS3557743 SRA741696 Gov of Canada Gov of Canada 1 0.9554   0.06997   0.79275   0.52557   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48947 48947 SRR7535405 SRX4403253 SRS3557742 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample24 F3CTR3   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR3 L24 F3CTR3 L24 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR3.fastq.gz fastq 2619378393.0 31091747.0 F3CTR3.fastq.gz 0:84.25 1:0 A:699692748;C:600624113;G:564410765;T:754600796;N:49971 84 0     699692748 600624113 564410765 754600796 49971 SRX4403253 SRS3557742 SRA741696 Gov of Canada Gov of Canada 1 0.95974   0.06076   0.7932   0.54096   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48948 48948 SRR7535406 SRX4403252 SRS3557741 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample25 F3CTR4   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR4 L25 F3CTR4 L25 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR4.fastq.gz fastq 3292260052.0 39078900.0 F3CTR4.fastq.gz 0:84.25 1:0 A:880017890;C:753064780;G:705989117;T:953125639;N:62626 84 0     880017890 753064780 705989117 953125639 62626 SRX4403252 SRS3557741 SRA741696 Gov of Canada Gov of Canada 1 0.95321   0.07242   0.75666   0.54587   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48949 48949 SRR7535407 SRX4403251 SRS3557740 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample26 F3CTR5   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR5 L26 F3CTR5 L26 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR5.fastq.gz fastq 3007976354.0 35696121.0 F3CTR5.fastq.gz 0:84.27 1:0 A:778578191;C:708292962;G:650565998;T:870481710;N:57493 84 0     778578191 708292962 650565998 870481710 57493 SRX4403251 SRS3557740 SRA741696 Gov of Canada Gov of Canada 1 0.95344   0.06722   0.7597   0.52143   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48950 48950 SRR7535408 SRX4403250 SRS3557739 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample27 F3CTR6   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR6 L27 F3CTR6 L27 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR6.fastq.gz fastq 2550867627.0 31161224.0 F3CTR6.fastq.gz 0:81.86 1:0 A:1115959207;C:419324274;G:453781546;T:561761915;N:40685 81 0     1115959207 419324274 453781546 561761915 40685 SRX4403250 SRS3557739 SRA741696 Gov of Canada Gov of Canada 1 0.92888   0.24434   0.77749   0.51629   76   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48951 48951 SRR7535409 SRX4403249 SRS3557738 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample28 F3CTR7   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR7 L28 F3CTR7 L28 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR7.fastq.gz fastq 2059768786.0 24468469.0 F3CTR7.fastq.gz 0:84.18 1:0 A:558059300;C:468460643;G:436031484;T:597176496;N:40863 84 0     558059300 468460643 436031484 597176496 40863 SRX4403249 SRS3557738 SRA741696 Gov of Canada Gov of Canada 1 0.94686   0.07284   0.77459   0.54014   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48952 48952 SRR7535410 SRX4403248 SRS3557737 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample29 F3CTR8   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3CTR8 L29 F3CTR8 L29 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3CTR8.fastq.gz fastq 3053213414.0 36279614.0 F3CTR8.fastq.gz 0:84.16 1:0 A:815581740;C:713814496;G:673475187;T:850294355;N:47636 84 0     815581740 713814496 673475187 850294355 47636 SRX4403248 SRS3557737 SRA741696 Gov of Canada Gov of Canada 1 0.9571   0.06714   0.75369   0.54721   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48953 48953 SRR7535411 SRX4403247 SRS3557736 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample30 F3LFL1   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL1 L30 F3LFL1 L30 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL1.fastq.gz fastq 2028343411.0 26987895.0 F3LFL1.fastq.gz 0:75.16 1:0 A:548593649;C:466971074;G:433327481;T:579386722;N:64485 75 0     548593649 466971074 433327481 579386722 64485 SRX4403247 SRS3557736 SRA741696 Gov of Canada Gov of Canada 1 0.95498   0.0741   0.7895   0.5309   75   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-07-18 Adult Adult Kidney Renal System
48954 48954 SRR7535412 SRX4403246 SRS3557735 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample8 F0CTR8   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR8 L8 F0CTR8 L8 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR8.fastq.gz fastq 2222889019.0 29574868.0 F0CTR8.fastq.gz 0:75.16 1:0 A:596733500;C:518690507;G:486721856;T:620675208;N:67948 75 0     596733500 518690507 486721856 620675208 67948 SRX4403246 SRS3557735 SRA741696 Gov of Canada Gov of Canada 1 0.95446   0.05545   0.74815   0.51889   74   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48955 48955 SRR7535413 SRX4403245 SRS3557734 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample7 F0CTR7   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR7 L7 F0CTR7 L7 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR7.fastq.gz fastq 4544318503.0 53947186.0 F0CTR7.fastq.gz 0:84.24 1:0 A:1292030811;C:991354554;G:942494048;T:1318393334;N:45756 84 0     1292030811 991354554 942494048 1318393334 45756 SRX4403245 SRS3557734 SRA741696 Gov of Canada Gov of Canada 1 0.9503   0.06778   0.75743   0.55348   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-07-18 Adult Adult Kidney Renal System
48956 48956 SRR7535414 SRX4403244 SRS3557733 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample6 F0CTR6   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR6 L6 F0CTR6 L6 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR6.fastq.gz fastq 2358891923.0 31391321.0 F0CTR6.fastq.gz 0:75.14 1:0 A:685288644;C:509459791;G:472389125;T:691678243;N:76120 75 0     685288644 509459791 472389125 691678243 76120 SRX4403244 SRS3557733 SRA741696 Gov of Canada Gov of Canada 1 0.94166   0.07795   0.76195   0.53942   75   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48957 48957 SRR7535415 SRX4403243 SRS3557732 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample5 F0CTR5   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR5 L5 F0CTR5 L5 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR5.fastq.gz fastq 2588676344.0 30755117.0 F0CTR5.fastq.gz 0:84.17 1:0 A:720655179;C:582123937;G:551878210;T:733977893;N:41125 84 0     720655179 582123937 551878210 733977893 41125 SRX4403243 SRS3557732 SRA741696 Gov of Canada Gov of Canada 1 0.95586   0.06561   0.7808   0.54698   83   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48958 48958 SRR7535416 SRX4403242 SRS3557731 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample4 F0CTR4   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR4 L4 F0CTR4 L4 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR4.fastq.gz fastq 2959885275.0 35175450.0 F0CTR4.fastq.gz 0:84.15 1:0 A:799876836;C:675392846;G:616854860;T:867718008;N:42725 84 0     799876836 675392846 616854860 867718008 42725 SRX4403242 SRS3557731 SRA741696 Gov of Canada Gov of Canada 1 0.93974   0.07556   0.76238   0.50131   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48959 48959 SRR7535417 SRX4403241 SRS3557730 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample3 F0CTR3   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR3 L3 F0CTR3 L3 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR3.fastq.gz fastq 3127991402.0 37019173.0 F0CTR3.fastq.gz 0:84.50 1:0 A:886233117;C:699410395;G:659031655;T:883271353;N:44882 84 0     886233117 699410395 659031655 883271353 44882 SRX4403241 SRS3557730 SRA741696 Gov of Canada Gov of Canada 1 0.95481   0.06332   0.77818   0.54263   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48960 48960 SRR7535418 SRX4403240 SRS3557729 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample2 F0CTR2   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR2 L2 F0CTR2 L2 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR2.fastq.gz fastq 4589246236.0 54480219.0 F0CTR2.fastq.gz 0:84.24 1:0 A:1318726005;C:987643623;G:940290206;T:1342543647;N:42755 84 0     1318726005 987643623 940290206 1342543647 42755 SRX4403240 SRS3557729 SRA741696 Gov of Canada Gov of Canada 1 0.94686   0.06888   0.76278   0.55045   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48961 48961 SRR7535419 SRX4403239 SRS3557728 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample1 F0CTR1   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0CTR1 L1 F0CTR1 L1 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0CTR1.fastq.gz fastq 2895973720.0 34407735.0 F0CTR1.fastq.gz 0:84.17 1:0 A:805217942;C:647195655;G:615425828;T:828086852;N:47443 84 0     805217942 647195655 615425828 828086852 47443 SRX4403239 SRS3557728 SRA741696 Gov of Canada Gov of Canada 1 0.95771   0.05823   0.75475   0.54018   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-07-18 Adult Adult Kidney Renal System
48962 48962 SRR7535420 SRX4403238 SRS3557727 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample10 F0LFL2   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0LFL2 L10 F0LFL2 L10 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0LFL2.fastq.gz fastq 2221964224.0 29564609.0 F0LFL2.fastq.gz 0:75.16 1:0 A:622205890;C:491850489;G:469917376;T:637922036;N:68433 75 0     622205890 491850489 469917376 637922036 68433 SRX4403238 SRS3557727 SRA741696 Gov of Canada Gov of Canada 1 0.95207   0.06132   0.76404   0.5374   76   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48963 48963 SRR7535421 SRX4403237 SRS3557726 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample9 F0LFL1   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0LFL1 L9 F0LFL1 L9 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0LFL1.fastq.gz fastq 3222133895.0 38154313.0 F0LFL1.fastq.gz 0:84.45 1:0 A:920033678;C:715675242;G:671297913;T:915080329;N:46733 84 0     920033678 715675242 671297913 915080329 46733 SRX4403237 SRS3557726 SRA741696 Gov of Canada Gov of Canada 1 0.95496   0.07355   0.76644   0.54508   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48964 48964 SRR7535422 SRX4403236 SRS3557725 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample20 F0HFL7   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL7 L20 F0HFL7 L20 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL7.fastq.gz fastq 2800528980.0 33270152.0 F0HFL7.fastq.gz 0:84.18 1:0 A:745732773;C:657771159;G:624594638;T:772385369;N:45041 84 0     745732773 657771159 624594638 772385369 45041 SRX4403236 SRS3557725 SRA741696 Gov of Canada Gov of Canada 1 0.9603   0.05557   0.75262   0.53229   83   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48965 48965 SRR7535423 SRX4403235 SRS3557724 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample19 F0HFL6   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL6 L19 F0HFL6 L19 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL6.fastq.gz fastq 3859582889.0 45819776.0 F0HFL6.fastq.gz 0:84.23 1:0 A:1042286597;C:895964648;G:843235146;T:1078059877;N:36621 84 0     1042286597 895964648 843235146 1078059877 36621 SRX4403235 SRS3557724 SRA741696 Gov of Canada Gov of Canada 1 0.95288   0.06929   0.74   0.52268   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48966 48966 SRR7535424 SRX4403234 SRS3557723 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample16 F0HFL3   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL3 L16 F0HFL3 L16 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL3.fastq.gz fastq 3793212903.0 45071794.0 F0HFL3.fastq.gz 0:84.16 1:0 A:1056360853;C:843514256;G:810627279;T:1082649387;N:61128 84 0     1056360853 843514256 810627279 1082649387 61128 SRX4403234 SRS3557723 SRA741696 Gov of Canada Gov of Canada 1 0.95323   0.06159   0.76195   0.54295   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48967 48967 SRR7535425 SRX4403233 SRS3557722 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample15 F0HFL2   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL2 L15 F0HFL2 L15 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL2.fastq.gz fastq 1653605409.0 19670232.0 F0HFL2.fastq.gz 0:84.07 1:0 A:482659933;C:340033054;G:332925206;T:497960425;N:26791 84 0     482659933 340033054 332925206 497960425 26791 SRX4403233 SRS3557722 SRA741696 Gov of Canada Gov of Canada 1 0.94378   0.07818   0.76654   0.56019   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48968 48968 SRR7535426 SRX4403232 SRS3557721 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample18 F0HFL5   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL5 L18 F0HFL5 L18 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL5.fastq.gz fastq 2841372173.0 33797215.0 F0HFL5.fastq.gz 0:84.07 1:0 A:778391982;C:632117929;G:585902045;T:844912619;N:47598 84 0     778391982 632117929 585902045 844912619 47598 SRX4403232 SRS3557721 SRA741696 Gov of Canada Gov of Canada 1 0.93559   0.07561   0.76895   0.55817   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48969 48969 SRR7535427 SRX4403231 SRS3557719 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample17 F0HFL4   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL4 L17 F0HFL4 L17 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL4.fastq.gz fastq 3160174261.0 37565835.0 F0HFL4.fastq.gz 0:84.12 1:0 A:884296991;C:697282059;G:667815635;T:910728716;N:50860 84 0     884296991 697282059 667815635 910728716 50860 SRX4403231 SRS3557719 SRA741696 Gov of Canada Gov of Canada 1 0.95258   0.06896   0.75753   0.53648   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48970 48970 SRR7535428 SRX4403230 SRS3557720 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample12 F0LFL4   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0LFL4 L12 F0LFL4 L12 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0LFL4.fastq.gz fastq 2872309444.0 34017640.0 F0LFL4.fastq.gz 0:84.44 1:0 A:838123566;C:615148814;G:580099793;T:838897200;N:40071 84 0     838123566 615148814 580099793 838897200 40071 SRX4403230 SRS3557720 SRA741696 Gov of Canada Gov of Canada 1 0.94655   0.07484   0.76055   0.53193   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48971 48971 SRR7535429 SRX4403229 SRS3557718 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample11 F0LFL3   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0LFL3 L11 F0LFL3 L11 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0LFL3.fastq.gz fastq 4819656374.0 57208863.0 F0LFL3.fastq.gz 0:84.25 1:0 A:1344664833;C:1065935819;G:1021114550;T:1387895714;N:45458 84 0     1344664833 1065935819 1021114550 1387895714 45458 SRX4403229 SRS3557718 SRA741696 Gov of Canada Gov of Canada 1 0.94968   0.06704   0.75063   0.53941   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48972 48972 SRR7535430 SRX4403228 SRS3557717 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample14 F0HFL1   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0HFL1 L14 F0HFL1 L14 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0HFL1.fastq.gz fastq 4382160649.0 58413517.0 F0HFL1.fastq.gz 0:75.02 1:0 A:1369437301;C:861646512;G:809593345;T:1341341422;N:142069 75 0     1369437301 861646512 809593345 1341341422 142069 SRX4403228 SRS3557717 SRA741696 Gov of Canada Gov of Canada 1 0.9466   0.08719   0.7794   0.54372   75   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-07-18 Adult Adult Kidney Renal System
48973 48973 SRR7535431 SRX4403227 SRS3557716 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample13 F0LFL5   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F0LFL5 L13 F0LFL5 L13 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F0LFL5.fastq.gz fastq 4135324561.0 55077889.0 F0LFL5.fastq.gz 0:75.08 1:0 A:1152758595;C:923324532;G:883060803;T:1176048511;N:132120 75 0     1152758595 923324532 883060803 1176048511 132120 SRX4403227 SRS3557716 SRA741696 Gov of Canada Gov of Canada 1 0.94936   0.07427   0.7385   0.54293   76   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48974 48974 SRR7535432 SRX4403226 SRS3557715 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample38 F3HFL1   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3HFL1 L38 F3HFL1 L38 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3HFL1.fastq.gz fastq 4205002265.0 49802474.0 F3HFL1.fastq.gz 0:84.43 1:0 A:1296210304;C:849397168;G:835453941;T:1223875076;N:65776 84 0     1296210304 849397168 835453941 1223875076 65776 SRX4403226 SRS3557715 SRA741696 Gov of Canada Gov of Canada 1 0.95559   0.0917   0.78044   0.61361   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48975 48975 SRR7535433 SRX4403225 SRS3557714 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample37 F3LFL8   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL8 L37 F3LFL8 L37 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL8.fastq.gz fastq 2259705259.0 26829092.0 F3LFL8.fastq.gz 0:84.23 1:0 A:609862793;C:515167321;G:475663194;T:658969872;N:42079 84 0     609862793 515167321 475663194 658969872 42079 SRX4403225 SRS3557714 SRA741696 Gov of Canada Gov of Canada 1 0.94002   0.10434   0.75369   0.51155   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48976 48976 SRR7535434 SRX4403224 SRS3557713 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample36 F3LFL7   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL7 L36 F3LFL7 L36 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL7.fastq.gz fastq 2341138815.0 27781759.0 F3LFL7.fastq.gz 0:84.27 1:0 A:608466569;C:545924123;G:501493228;T:685210306;N:44589 84 0     608466569 545924123 501493228 685210306 44589 SRX4403224 SRS3557713 SRA741696 Gov of Canada Gov of Canada 1 0.94523   0.08263   0.75284   0.53752   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48977 48977 SRR7535435 SRX4403223 SRS3557712 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample35 F3LFL6   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL6 L35 F3LFL6 L35 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL6.fastq.gz fastq 2937598885.0 34879736.0 F3LFL6.fastq.gz 0:84.22 1:0 A:782454526;C:678806792;G:617210082;T:859072883;N:54602 84 0     782454526 678806792 617210082 859072883 54602 SRX4403223 SRS3557712 SRA741696 Gov of Canada Gov of Canada 1 0.94207   0.08495   0.74897   0.5069   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48978 48978 SRR7535436 SRX4403222 SRS3557711 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample34 F3LFL5   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL5 L34 F3LFL5 L34 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL5.fastq.gz fastq 2497066825.0 29658022.0 F3LFL5.fastq.gz 0:84.20 1:0 A:694874960;C:555774576;G:516525097;T:729844057;N:48135 84 0     694874960 555774576 516525097 729844057 48135 SRX4403222 SRS3557711 SRA741696 Gov of Canada Gov of Canada 1 0.94238   0.09347   0.76404   0.51048   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48979 48979 SRR7535437 SRX4403221 SRS3557710 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample33 F3LFL4   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL4 L33 F3LFL4 L33 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL4.fastq.gz fastq 3167171318.0 37581804.0 F3LFL4.fastq.gz 0:84.27 1:0 A:836474638;C:736638892;G:687417511;T:906580806;N:59471 84 0     836474638 736638892 687417511 906580806 59471 SRX4403221 SRS3557710 SRA741696 Gov of Canada Gov of Canada 1 0.95381   0.0776   0.74432   0.49786   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48980 48980 SRR7535438 SRX4403220 SRS3557709 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample32 F3LFL3   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL3 L32 F3LFL3 L32 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL3.fastq.gz fastq 3969872568.0 47103172.0 F3LFL3.fastq.gz 0:84.28 1:0 A:1087899347;C:891968649;G:846315646;T:1143611603;N:77323 84 0     1087899347 891968649 846315646 1143611603 77323 SRX4403220 SRS3557709 SRA741696 Gov of Canada Gov of Canada 1 0.94717   0.08461   0.74714   0.53355   84   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48981 48981 SRR7535439 SRX4403219 SRS3557708 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample31 F3LFL2   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3LFL2 L31 F3LFL2 L31 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3LFL2.fastq.gz fastq 2401613544.0 31959346.0 F3LFL2.fastq.gz 0:75.15 1:0 A:673230842;C:536445759;G:492980009;T:698882870;N:74064 75 0     673230842 536445759 492980009 698882870 74064 SRX4403219 SRS3557708 SRA741696 Gov of Canada Gov of Canada 1 0.95198   0.08486   0.7878   0.55398   75   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48982 48982 SRR7535440 SRX4403218 SRS3557706 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample40 F3HFL3   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3HFL3 L40 F3HFL3 L40 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3HFL3.fastq.gz fastq 2266960447.0 26913177.0 F3HFL3.fastq.gz 0:84.23 1:0 A:590021990;C:520283209;G:479594101;T:677024566;N:36581 84 0     590021990 520283209 479594101 677024566 36581 SRX4403218 SRS3557706 SRA741696 Gov of Canada Gov of Canada 1 0.94897   0.08251   0.80848   0.57355   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
48983 48983 SRR7535441 SRX4403217 SRS3557707 SRP154295 PRJNA481502 Transgenerational hypocortisolism and behavioral disruption is induced by the antidepressant fluoxetine in male zebrafish Danio rerio PRJNA481502 Transcriptome Analysis Transcriptomic profiling of the whole kidney revealed that early fluoxetine exposure significantly transgenerationally modified numerous pathways closely associated with cortisol synthesis in the male adults from the F0 and F3 generations.   pubmed:30530669   sample39 F3HFL2   strain:AB strain|age:6 mpf organism or animal                 RNA seq of Danio rerio: male kidney F3HFL2 L39 F3HFL2 L39 mRNA seq from total RNA on Illumina Neoprep     RNA-Seq TRANSCRIPTOMIC PolyA SINGLE ILLUMINA NextSeq 500   SRP154295     F3HFL2.fastq.gz fastq 2749128323.0 32649931.0 F3HFL2.fastq.gz 0:84.20 1:0 A:739282939;C:602311637;G:590565979;T:816929591;N:38177 84 0     739282939 602311637 590565979 816929591 38177 SRX4403217 SRS3557707 SRA741696 Gov of Canada Gov of Canada 1 0.9613   0.09046   0.8104   0.62158   85   B   usable mapping rate illumina nextseq unknown poly_a unknown bulk unknown unknown   Canada 2018-12-11 Adult Adult Kidney Renal System
68331 68331 SRR17714674 SRX13877735 SRS11747907 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         KO ki 2   strain:AB type|isolate:knockout|breed:KO ki 2|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish KO ki 2 KO ki 2 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_KO-ki-2_good_1.fq.gz Daniorerio_KO-ki-2_good_2.fq.gz fastq fastq 6459301738.0 21580856.0 Daniorerio KO ki 2 good 1.fq.gz 0:149.65 1:149.65 A:1784875806;C:1432248891;G:1473557552;T:1768292520;N:326969 149 149     1784875806 1432248891 1473557552 1768292520 326969 SRX13877735 SRS11747907 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.92356 0.92283 0.11927 0.11877 0.69116 0.69286 0.51648 0.51904 122 122 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68332 68332 SRR17714675 SRX13877734 SRS11747908 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         KO ki 1   strain:AB type|isolate:knockout|breed:KO ki 1|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish KO ki 1 KO ki 1 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_KO-ki-1_good_1.fq.gz Daniorerio_KO-ki-1_good_2.fq.gz fastq fastq 6099339068.0 20376162.0 Daniorerio KO ki 1 good 1.fq.gz 0:149.67 1:149.67 A:1680007435;C:1355561431;G:1393826814;T:1669638827;N:304561 149 149     1680007435 1355561431 1393826814 1669638827 304561 SRX13877734 SRS11747908 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.92276 0.92011 0.1239 0.12427 0.69353 0.69457 0.52537 0.52715 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68340 68340 SRR17714683 SRX13877726 SRS11747899 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         WT ki 7   strain:AB type|isolate:wild type|breed:WT ki 7|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish WT ki 7 WT ki 7 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_WT-ki-7_good_1.fq.gz Daniorerio_WT-ki-7_good_2.fq.gz fastq fastq 5728682916.0 19186928.0 Daniorerio WT ki 7 good 1.fq.gz 0:149.29 1:149.29 A:1579153464;C:1273656952;G:1312180039;T:1563403341;N:289120 149 149     1579153464 1273656952 1312180039 1563403341 289120 SRX13877726 SRS11747899 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.93765 0.9349 0.10683 0.10543 0.71248 0.71313 0.48682 0.50333 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68341 68341 SRR17714684 SRX13877725 SRS11747898 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         WT ki 4   strain:AB type|isolate:wild type|breed:WT ki 4|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish WT ki 4 WT ki 4 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_WT-ki-4_good_1.fq.gz Daniorerio_WT-ki-4_good_2.fq.gz fastq fastq 6538230102.0 21840569.0 Daniorerio WT ki 4 good 1.fq.gz 0:149.68 1:149.68 A:1712166805;C:1543306905;G:1570047290;T:1712688420;N:20682 149 149     1712166805 1543306905 1570047290 1712688420 20682 SRX13877725 SRS11747898 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.93239 0.93289 0.03511 0.03508 0.71285 0.71313 0.4785 0.48034 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68342 68342 SRR17714685 SRX13877724 SRS11747897 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         WT ki 3   strain:AB type|isolate:wild type|breed:WT ki 3|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish WT ki 3 WT ki 3 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_WT-ki-3_good_1.fq.gz Daniorerio_WT-ki-3_good_2.fq.gz fastq fastq 6535179260.0 21823644.0 Daniorerio WT ki 3 good 1.fq.gz 0:149.73 1:149.73 A:1783453491;C:1473349126;G:1511499971;T:1766854951;N:21721 149 149     1783453491 1473349126 1511499971 1766854951 21721 SRX13877724 SRS11747897 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.93369 0.93255 0.097 0.09643 0.67848 0.6788 0.51146 0.50793 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68343 68343 SRR17714686 SRX13877723 SRS11747896 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         WT ki 2   strain:AB type|isolate:wild type|breed:WT ki 2|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish WT ki 2 WT ki 2 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_WT-ki-2_good_1.fq.gz Daniorerio_WT-ki-2_good_2.fq.gz fastq fastq 7459816636.0 24952918.0 Daniorerio WT ki 2 good 1.fq.gz 0:149.48 1:149.48 A:2038726076;C:1677988595;G:1720392114;T:2022686081;N:23770 149 149     2038726076 1677988595 1720392114 2022686081 23770 SRX13877723 SRS11747896 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.92812 0.92786 0.12105 0.12019 0.69347 0.69463 0.51823 0.51342 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68358 68358 SRR17714701 SRX13877708 SRS11747880 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         MU ki 4   strain:AB type|isolate:point mutation|breed:MU ki 4|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish MU ki 4 MU ki 4 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_MU-ki-4_good_1.fq.gz Daniorerio_MU-ki-4_good_2.fq.gz fastq fastq 6642468464.0 22227277.0 Daniorerio MU ki 4 good 1.fq.gz 0:149.42 1:149.42 A:1806510861;C:1499915463;G:1544497199;T:1791210925;N:334016 149 149     1806510861 1499915463 1544497199 1791210925 334016 SRX13877708 SRS11747880 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.93502 0.93305 0.0993 0.09919 0.68519 0.68617 0.50471 0.502 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68359 68359 SRR17714702 SRX13877707 SRS11747881 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         MU ki 3   strain:AB type|isolate:point mutation|breed:MU ki 3|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish MU ki 3 MU ki 3 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_MU-ki-3_good_1.fq.gz Daniorerio_MU-ki-3_good_2.fq.gz fastq fastq 8129697250.0 27275691.0 Daniorerio MU ki 3 good 1.fq.gz 0:149.03 1:149.03 A:2186818686;C:1865874012;G:1906801031;T:2169800472;N:403049 149 149     2186818686 1865874012 1906801031 2169800472 403049 SRX13877707 SRS11747881 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.93373 0.93291 0.09256 0.09199 0.68363 0.68582 0.50121 0.49901 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68360 68360 SRR17714703 SRX13877706 SRS11747879 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         MU ki 2   strain:AB type|isolate:point mutation|breed:MU ki 2|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish MU ki 2 MU ki 2 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_MU-ki-2_good_1.fq.gz Daniorerio_MU-ki-2_good_2.fq.gz fastq fastq 8613479966.0 28864538.0 Daniorerio MU ki 2 good 1.fq.gz 0:149.21 1:149.21 A:2341268944;C:1952093439;G:1997306668;T:2322383690;N:427225 149 149     2341268944 1952093439 1997306668 2322383690 427225 SRX13877706 SRS11747879 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.92686 0.92514 0.10387 0.10349 0.68278 0.68465 0.5126 0.51299 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68361 68361 SRR17714704 SRX13877705 SRS11747878 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         MU ki 1   strain:AB type|isolate:point mutation|breed:MU ki 1|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish MU ki 1 MU ki 1 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_MU-ki-1_good_1.fq.gz Daniorerio_MU-ki-1_good_2.fq.gz fastq fastq 6361721340.0 21272731.0 Daniorerio MU ki 1 good 1.fq.gz 0:149.53 1:149.53 A:1764729780;C:1403968855;G:1444221125;T:1748483646;N:317934 149 149     1764729780 1403968855 1444221125 1748483646 317934 SRX13877705 SRS11747878 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.91983 0.91698 0.11213 0.11 0.69603 0.69816 0.51786 0.51691 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68375 68375 SRR17714718 SRX13877691 SRS11747864 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         KO ki 4   strain:AB type|isolate:knockout|breed:KO ki 4|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish KO ki 4 KO ki 4 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_KO-ki-4_good_1.fq.gz Daniorerio_KO-ki-4_good_2.fq.gz fastq fastq 7271417184.0 24262326.0 Daniorerio KO ki 4 good 1.fq.gz 0:149.85 1:149.85 A:1942212311;C:1672440540;G:1729389358;T:1927007172;N:367803 149 149     1942212311 1672440540 1729389358 1927007172 367803 SRX13877691 SRS11747864 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.93084 0.92784 0.10122 0.10007 0.70496 0.70648 0.52353 0.51998 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68376 68376 SRR17714719 SRX13877690 SRS11747863 SRP356388 PRJNA799842 RNA seq of CRISPR/Cas9 mediated genome editing zebrafishes; the alligator pipefish spleen and the small white organ of the lined seahorse. PRJNA799842 Other To explore the function of the gene in spleen development we generated a knockout zebrafish line. To investigate whether the phenotypic consequences in the seahorses were caused by a missense mutation in this gene we generated a point mutation zebrafish line by CRISPR/Cas9 mediated homologous recombination HR. RNA seq of these samples tissues brain liver kidney and intestine were analyzed. In addition to clarify the splenic phenotype of the Syngnathidaes the transcriptomic profiles of the S. biaculeatus spleens and the H. erectus small white organ were also sampled and sequenced.         KO ki 3   strain:AB type|isolate:knockout|breed:KO ki 3|age:3 month|dev stage:NA|sex:NA|tissue:kidney|BioSampleModel:Model organism or animal                 RNA seq of zebrafish KO ki 3 KO ki 3 RNA seq     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina HiSeq 2500   SRP356388   loader:fastq load.py Daniorerio_KO-ki-3_good_1.fq.gz Daniorerio_KO-ki-3_good_2.fq.gz fastq fastq 7380278536.0 24738542.0 Daniorerio KO ki 3 good 1.fq.gz 0:149.17 1:149.17 A:1960997842;C:1716280740;G:1751732155;T:1950894353;N:373446 149 149     1960997842 1716280740 1751732155 1950894353 373446 SRX13877690 SRS11747863 SRA1360632 South China Sea Institute of Oceanology|CAS Key Laboratory of Tropical Marine Bio-Resource South China Sea Institute of Oceanology 2 0.92496 0.9235 0.12088 0.11977 0.69923 0.69968 0.53733 0.53696 150 150 B B biological fallback assumption illumina hiseq_era unknown poly_a unknown bulk unknown unknown   China 2022-01-27 Adult Adult Kidney Renal System
68886 68886 SRR18218068 SRX14364510 SRS12177805 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 1   strain:CG1|age:not collected|sex:not collected|tissue:whole kidney marrow|birth date: |death date:16 07 2019|genotype:Wild type|biological replicate:WKM CG1 biological replicate 1|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow CG1 WKM CG1 1 WKM CG1 1 CG1 WT zebrafish were sacrificed to harvest the whole kidney marrow WKM for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAARAAPEI-P1A1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAARAAPEI-P1A1_2.fq.gz fastq fastq 18015161100.0 60050537.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAARAAPEI P1A1 1.fq.gz 0:150 1:150 A:4626900295;C:4400273225;G:4421661364;T:4566300408;N:25808 150 150     4626900295 4400273225 4421661364 4566300408 25808 SRX14364510 SRS12177805 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94715 0.94844 0.03897 0.03893 0.72176 0.72182 0.51658 0.50581 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Undetermined Undetermined Kidney Renal System
68901 68901 SRR18218080 SRX14364495 SRS12177790 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 P2mut 7   strain:CG1|age:8 month|sex:not collected|tissue:whole kidney marrow|birth date:17 11 2018|death date:17 07 2019|genotype:rag2:hIL7R mut2 tdTomato|biological replicate:WKM CG1 P2mut biological replicate 6|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow stably expressing human mutant IL7R CG1 WKM CG1 P2mut 7 WKM CG1 P2mut 7 CG1 zebrafish stably expressing human mutant IL7R were sacrificed without xxx of overt leukemia and whole kidney marrow WKM was harvested for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAKRAAPEI-P26C2_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAKRAAPEI-P26C2_2.fq.gz fastq fastq 16762989900.0 55876633.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAKRAAPEI P26C2 1.fq.gz 0:150 1:150 A:4442983154;C:3951385839;G:4007817362;T:4360778933;N:24612 150 150     4442983154 3951385839 4007817362 4360778933 24612 SRX14364495 SRS12177790 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94363 0.94514 0.04876 0.04869 0.73369 0.73379 0.53344 0.5343 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Adult Adult Kidney Renal System
68902 68902 SRR18218081 SRX14364494 SRS12177789 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 P2mut 6   strain:CG1|age:8 month|sex:not collected|tissue:whole kidney marrow|birth date:17 11 2018|death date:17 07 2019|genotype:rag2:hIL7R mut2 tdTomato|biological replicate:WKM CG1 P2mut biological replicate 5|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow stably expressing human mutant IL7R CG1 WKM CG1 P2mut 6 WKM CG1 P2mut 6 CG1 zebrafish stably expressing human mutant IL7R were sacrificed without xxx of overt leukemia and whole kidney marrow WKM was harvested for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAJRABPEI-P14B2_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAJRABPEI-P14B2_2.fq.gz fastq fastq 18194856000.0 60649520.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAJRABPEI P14B2 1.fq.gz 0:150 1:150 A:4776137612;C:4328521118;G:4394651128;T:4695520357;N:25785 150 150     4776137612 4328521118 4394651128 4695520357 25785 SRX14364494 SRS12177789 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94185 0.94348 0.05607 0.05578 0.73332 0.73281 0.5284 0.52266 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Adult Adult Kidney Renal System
68903 68903 SRR18218082 SRX14364493 SRS12177788 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 P2mut 5   strain:CG1|age:8 month|sex:not collected|tissue:whole kidney marrow|birth date:17 11 2018|death date:17 07 2019|genotype:rag2:hIL7R mut2 tdTomato|biological replicate:WKM CG1 P2mut biological replicate 4|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow stably expressing human mutant IL7R CG1 WKM CG1 P2mut 5 WKM CG1 P2mut 5 CG1 zebrafish stably expressing human mutant IL7R were sacrificed without xxx of overt leukemia and whole kidney marrow WKM was harvested for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAIRAAPEI-P2A2_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAIRAAPEI-P2A2_2.fq.gz fastq fastq 18218380200.0 60727934.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAIRAAPEI P2A2 1.fq.gz 0:150 1:150 A:4769839227;C:4349260666;G:4417289893;T:4681963719;N:26695 150 150     4769839227 4349260666 4417289893 4681963719 26695 SRX14364493 SRS12177788 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94341 0.94473 0.04954 0.04988 0.71192 0.7121 0.52338 0.52876 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Adult Adult Kidney Renal System
68904 68904 SRR18218083 SRX14364492 SRS12177787 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 P2mut 4   strain:CG1|age:8 month|sex:not collected|tissue:whole kidney marrow|birth date:17 11 2018|death date:17 07 2019|genotype:rag2:hIL7R mut2 tdTomato|biological replicate:WKM CG1 P2mut biological replicate 3|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow stably expressing human mutant IL7R CG1 WKM CG1 P2mut 4 WKM CG1 P2mut 4 CG1 zebrafish stably expressing human mutant IL7R were sacrificed without xxx of overt leukemia and whole kidney marrow WKM was harvested for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAHRABPEI-P85H1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAHRABPEI-P85H1_2.fq.gz fastq fastq 18205310400.0 60684368.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAHRABPEI P85H1 1.fq.gz 0:150 1:150 A:4801894426;C:4309153266;G:4380582553;T:4713653706;N:26449 150 150     4801894426 4309153266 4380582553 4713653706 26449 SRX14364492 SRS12177787 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94333 0.94441 0.04893 0.04829 0.73026 0.73101 0.52749 0.52823 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Adult Adult Kidney Renal System
68905 68905 SRR18218084 SRX14364491 SRS12177786 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 P2mut 3   strain:CG1|age:8 month|sex:not collected|tissue:whole kidney marrow|birth date:17 11 2018|death date:17 07 2019|genotype:rag2:hIL7R mut2 tdTomato|biological replicate:WKM CG1 P2mut biological replicate 2|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow stably expressing human mutant IL7R CG1 WKM CG1 P2mut 3 WKM CG1 P2mut 3 CG1 zebrafish stably expressing human mutant IL7R were sacrificed without xxx of overt leukemia and whole kidney marrow WKM was harvested for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAGRAAPEI-P73G1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAGRAAPEI-P73G1_2.fq.gz fastq fastq 18143381100.0 60477937.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAGRAAPEI P73G1 1.fq.gz 0:150 1:150 A:4669037373;C:4411451517;G:4473720090;T:4589145705;N:26415 150 150     4669037373 4411451517 4473720090 4589145705 26415 SRX14364491 SRS12177786 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94105 0.94205 0.0448 0.04442 0.71553 0.71581 0.5171 0.51695 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Adult Adult Kidney Renal System
68906 68906 SRR18218085 SRX14364490 SRS12177785 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 5   strain:CG1|age:not collected|sex:not collected|tissue:whole kidney marrow|birth date: |death date:16 07 2019|genotype:Wild type|biological replicate:WKM CG1 biological replicate 5|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow CG1 WKM CG1 5 WKM CG1 5 CG1 WT zebrafish were sacrificed to harvest the whole kidney marrow WKM for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAERABPEI-P49E1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAERABPEI-P49E1_2.fq.gz fastq fastq 18184234500.0 60614115.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAERABPEI P49E1 1.fq.gz 0:150 1:150 A:4903189861;C:4188361342;G:4259034739;T:4833623925;N:24633 150 150     4903189861 4188361342 4259034739 4833623925 24633 SRX14364490 SRS12177785 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.93501 0.93633 0.05446 0.05438 0.71583 0.71368 0.5862 0.56886 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Undetermined Undetermined Kidney Renal System
68907 68907 SRR18218087 SRX14364489 SRS12177784 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 4   strain:CG1|age:not collected|sex:not collected|tissue:whole kidney marrow|birth date: |death date:16 07 2019|genotype:Wild type|biological replicate:WKM CG1 biological replicate 4|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow CG1 WKM CG1 4 WKM CG1 4 CG1 WT zebrafish were sacrificed to harvest the whole kidney marrow WKM for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAADRAAPEI-P37D1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAADRAAPEI-P37D1_2.fq.gz fastq fastq 18145210500.0 60484035.0 FCHT5GHDSXX L1 HKRDZEBmfpEAADRAAPEI P37D1 1.fq.gz 0:150 1:150 A:4734947807;C:4358845691;G:4370947434;T:4680443888;N:25680 150 150     4734947807 4358845691 4370947434 4680443888 25680 SRX14364489 SRS12177784 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.93212 0.93296 0.05289 0.05244 0.71433 0.71465 0.5085 0.49253 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Undetermined Undetermined Kidney Renal System
68908 68908 SRR18218088 SRX14364488 SRS12177783 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 3   strain:CG1|age:not collected|sex:not collected|tissue:whole kidney marrow|birth date: |death date:16 07 2019|genotype:Wild type|biological replicate:WKM CG1 biological replicate 3|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow CG1 WKM CG1 3 WKM CG1 3 CG1 WT zebrafish were sacrificed to harvest the whole kidney marrow WKM for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAACRAAPEI-P25C1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAACRAAPEI-P25C1_2.fq.gz fastq fastq 18002689500.0 60008965.0 FCHT5GHDSXX L1 HKRDZEBmfpEAACRAAPEI P25C1 1.fq.gz 0:150 1:150 A:4624819223;C:4407791489;G:4420933608;T:4549119250;N:25930 150 150     4624819223 4407791489 4420933608 4549119250 25930 SRX14364488 SRS12177783 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94795 0.94827 0.03817 0.03816 0.72991 0.72987 0.49707 0.49202 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Undetermined Undetermined Kidney Renal System
68909 68909 SRR18218089 SRX14364487 SRS12177782 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 2   strain:CG1|age:not collected|sex:not collected|tissue:whole kidney marrow|birth date: |death date:16 07 2019|genotype:Wild type|biological replicate:WKM CG1 biological replicate 2|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow CG1 WKM CG1 2 WKM CG1 2 CG1 WT zebrafish were sacrificed to harvest the whole kidney marrow WKM for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAABRAAPEI-P13B1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAABRAAPEI-P13B1_2.fq.gz fastq fastq 18005451300.0 60018171.0 FCHT5GHDSXX L1 HKRDZEBmfpEAABRAAPEI P13B1 1.fq.gz 0:150 1:150 A:4630108478;C:4397001180;G:4413434449;T:4564880633;N:26560 150 150     4630108478 4397001180 4413434449 4564880633 26560 SRX14364487 SRS12177782 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.95098 0.95069 0.0373 0.03685 0.72312 0.72301 0.51708 0.51873 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Undetermined Undetermined Kidney Renal System
68910 68910 SRR18218086 SRX14364486 SRS12177781 SRP362416 PRJNA812715 Mutant IL7R collaborates with MYC to induce T cell Acute Lymphoblastic Leukemia PRJNA812715 Other T cell acute lymphoblastic leukemia T ALL is an aggressive pediatric cancer. Amongst the wide array of driver mutations 10% of T ALL patients display gain of function mutations in the IL 7 receptor alpha chain IL 7Ralpha encoded by IL7R which occur in different molecular subtypes of this disease. However it is still unclear whether IL 7R mutational activation is sufficient to transform T cell precursors. Also which genes cooperate with IL7R to drive leukemogenesis remain poorly defined. Here we demonstrate that mutant IL7R alone is capable of inducing T ALL with long latency in stable transgenic zebrafish and transformation is associated with MYC transcriptional activation. Additionally we find that mutant IL7R collaborates with Myc to induce early onset T ALL in transgenic zebrafish. T ALLs co expressing mutant IL7R and Myc show activation of STAT5 and AKT pathways harbor reduced numbers of apoptotic cells and remake tumors in transplanted zebrafish faster than T ALLs expressing Myc alone. Moreover limiting dilution cell transplantation experiments reveal that activated IL 7R signaling increases the overall frequency of leukemia propagating cells. Our work highlights a synergy between mutant IL7R and Myc in inducing T ALL and demonstrates that mutant IL7R enriches for leukemia propagating potential.         WKM CG1 P2mut 2   strain:CG1|age:16 month|sex:not collected|tissue:whole kidney marrow|birth date:17 03 2018|death date:17 07 2019|genotype:rag2:hIL7R mut2 tdTomato|biological replicate:WKM CG1 P2mut biological replicate 1|BioSampleModel:Model organism or animal                 RNA seq of Danio rerio whole kidney marrow stably expressing human mutant IL7R CG1 WKM CG1 P2mut 2 WKM CG1 P2mut 2 CG1 zebrafish stably expressing human mutant IL7R were sacrificed without xxx of overt leukemia and whole kidney marrow WKM was harvested for further analysis. The RNA was extracted from WKM cells using the RNeasy Mini Kit according to the manufacturers instructions Qiagen. mRNA was enriched using magnetic beads with Oligo dT fragmented and converted to cDNA size selected and PCR amplified generating paired end 100 bp sequences using a Illumina NovaSeq 6000.     RNA-Seq TRANSCRIPTOMIC PolyA PAIRED ILLUMINA Illumina NovaSeq 6000   SRP362416     FCHT5GHDSXX_L1_HKRDZEBmfpEAAFRAAPEI-P61F1_1.fq.gz FCHT5GHDSXX_L1_HKRDZEBmfpEAAFRAAPEI-P61F1_2.fq.gz fastq fastq 18210767700.0 60702559.0 FCHT5GHDSXX L1 HKRDZEBmfpEAAFRAAPEI P61F1 1.fq.gz 0:150 1:150 A:4648945418;C:4475968423;G:4497341113;T:4588486811;N:25935 150 150     4648945418 4475968423 4497341113 4588486811 25935 SRX14364486 SRS12177781 SRA1380603 Instituto de Medicina Molecular Joao Lobo Antunes|JBarata lab Instituto de Medicina Molecular Joao Lobo Antunes 2 0.94563 0.94587 0.03836 0.03819 0.73148 0.73042 0.49281 0.49845 150 150 B B biological fallback assumption illumina novaseq_era unknown poly_a unknown bulk unknown unknown   Portugal 2022-03-04 Adult Adult Kidney Renal System

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CREATE TABLE run_metadata("run.accession" VARCHAR, "experiment.accession" VARCHAR, "sample.accession" VARCHAR, "study.accession" VARCHAR, bioproject VARCHAR, "study.title" VARCHAR, "study.alias" VARCHAR, "study.type" VARCHAR, "study.abstract" VARCHAR, "study.attributes" VARCHAR, "study.PMIDs" VARCHAR, "sample.description" VARCHAR, "sample.title" VARCHAR, "sample.alias" VARCHAR, "sample.centername" VARCHAR, "sample.attributes" VARCHAR, "GEOsample.title" VARCHAR, "GEOsample.dataprocessing" VARCHAR, "GEOsample.source" VARCHAR, "GEOsample.treatmentprotocol" VARCHAR, "GEOsample.extractprotocol" VARCHAR, "GEOsample.growthprotocol" VARCHAR, "GEOsample.characteristics" VARCHAR, "GEOsample.accession" VARCHAR, "experiment.title" VARCHAR, "experiment.alias" VARCHAR, "experiment.library_name" VARCHAR, "experiment.design_description" VARCHAR, "experiment.library_construction_protocol" VARCHAR, "experiment.attributes" VARCHAR, "experiment.library_strategy" VARCHAR, "experiment.library_source" VARCHAR, "experiment.library_selection" VARCHAR, "experiment.library_layout" VARCHAR, "experiment.platform" VARCHAR, "experiment.instrument_model" VARCHAR, "experiment.spot_descriptor" VARCHAR, "experiment.study_ref" VARCHAR, "run.title" VARCHAR, "run.attributes" VARCHAR, "run.filename" VARCHAR, "run.semantic_name" VARCHAR, "run.total_bases" DOUBLE, "run.total_spots" DOUBLE, "run.alias" VARCHAR, "run.read_lengths" VARCHAR, "run.base_counts" VARCHAR, "run.r1_length" BIGINT, "run.r2_length" BIGINT, "run.r3_length" BIGINT, "run.r4_length" BIGINT, "run.Acount" BIGINT, "run.Ccount" BIGINT, "run.Gcount" BIGINT, "run.Tcount" BIGINT, "run.Ncount" BIGINT, "run.experiment" VARCHAR, "run.pool_member" VARCHAR, "submission.accession" VARCHAR, "submission.srasource" VARCHAR, "submission.bioprojectsource" VARCHAR, "seqdetective.n_mates" BIGINT, "seqdetective.mapping_rate.mate1" DOUBLE, "seqdetective.mapping_rate.mate2" DOUBLE, "seqdetective.nofeature_rate.mate1" DOUBLE, "seqdetective.nofeature_rate.mate2" DOUBLE, "seqdetective.sparsity.mate1" DOUBLE, "seqdetective.sparsity.mate2" DOUBLE, "seqdetective.pos_strand_rate.mate1" DOUBLE, "seqdetective.pos_strand_rate.mate2" DOUBLE, "seqdetective.readlen.mate1" BIGINT, "seqdetective.readlen.mate2" BIGINT, "seqdetective.judgement.mate1" VARCHAR, "seqdetective.judgement.mate2" VARCHAR, "seqdetective.judgement.reason" VARCHAR, platform_family VARCHAR, instrument_generation VARCHAR, read_bias VARCHAR, selection_class VARCHAR, prep_kit VARCHAR, sc_or_bulk VARCHAR, tech_class VARCHAR, technology VARCHAR, tech_variant VARCHAR, "submission.bioprojectsource.country" VARCHAR, earliest_date DATE, devstage_curation VARCHAR, devstage_curation_coarse VARCHAR, tissue_curation VARCHAR, tissue_curation_coarse VARCHAR);;
CREATE INDEX idx_run_bioproject ON run_metadata(bioproject);;
CREATE INDEX idx_run_run_accession ON run_metadata("run.accession");;