metadata: run_metadata: 38 rows where experiment.library_selection = "Oligo-dT", experiment.platform = "BGISEQ" and tissue_curation

38 rows where experiment.library_selection = "Oligo-dT", experiment.platform = "BGISEQ" and tissue_curation_coarse = "Undetermined"

descending

Link	rowid ▼	run.accession	experiment.accession	sample.accession	study.accession	bioproject	study.title	study.alias	study.type	study.abstract	sample.alias	sample.attributes	experiment.title	experiment.alias	experiment.library_name	experiment.design_description	experiment.library_strategy	experiment.library_source	experiment.library_selection	experiment.library_layout	experiment.platform	experiment.instrument_model	experiment.study_ref	run.attributes	run.filename	run.semantic_name	run.total_bases	run.total_spots	run.alias	run.read_lengths	run.base_counts	run.r1_length	run.r2_length	run.Acount	run.Ccount	run.Gcount	run.Tcount	run.Ncount	run.experiment	run.pool_member	submission.accession	submission.srasource	submission.bioprojectsource	seqdetective.n_mates	seqdetective.mapping_rate.mate1	seqdetective.nofeature_rate.mate1	seqdetective.sparsity.mate1	seqdetective.pos_strand_rate.mate1	seqdetective.readlen.mate1	seqdetective.judgement.mate1	seqdetective.judgement.mate2	seqdetective.judgement.reason	platform_family	instrument_generation	read_bias	selection_class	prep_kit	sc_or_bulk	tech_class	technology	submission.bioprojectsource.country	earliest_date	devstage_curation	devstage_curation_coarse	tissue_curation	tissue_curation_coarse
31825	31825	SRR28700412	SRX24268115	SRS21034395	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	PN 2	isolate:PN2\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 2\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	PN 2	PN 2	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		PN_2_1.fq.gz PN_2_2.fq.gz	fastq fastq	6385048200.0	21283494.0	PN 2 1.fq.gz	0:150 1:150	A:1722127999;C:1463645587;G:1483173818;T:1716100796;N:0	150	150	1722127999	1463645587	1483173818	1716100796	0	SRX24268115	SRS21034395			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31826	31826	SRR28700413	SRX24268114	SRS21034397	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	PN 1	isolate:PN1\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 1\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	PN 1	PN 1	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		PN_1_1.fq.gz PN_1_2.fq.gz	fastq fastq	6692894100.0	22309647.0	PN 1 1.fq.gz	0:150 1:150	A:1827107021;C:1513034624;G:1533077624;T:1819674831;N:0	150	150	1827107021	1513034624	1533077624	1819674831	0	SRX24268114	SRS21034397			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31827	31827	SRR28700414	SRX24268113	SRS21034396	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	EC 4	isolate:EC4\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 4\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	EC 4	EC 4	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		EC_4_1.fq.gz EC_4_2.fq.gz	fastq fastq	6688857000.0	22296190.0	EC 4 1.fq.gz	0:150 1:150	A:1820989545;C:1516814697;G:1537970654;T:1813082104;N:0	150	150	1820989545	1516814697	1537970654	1813082104	0	SRX24268113	SRS21034396			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31828	31828	SRR28700415	SRX24268112	SRS21034392	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	EC 3	isolate:EC3\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 3\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	EC 3	EC 3	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		EC_3_1.fq.gz EC_3_2.fq.gz	fastq fastq	6696553800.0	22321846.0	EC 3 1.fq.gz	0:150 1:150	A:1821249100;C:1520587242;G:1541238550;T:1813478908;N:0	150	150	1821249100	1520587242	1541238550	1813478908	0	SRX24268112	SRS21034392			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31829	31829	SRR28700416	SRX24268111	SRS21034391	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	EC 2	isolate:EC2\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 2\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	EC 2	EC 2	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		EC_2_1.fq.gz EC_2_2.fq.gz	fastq fastq	6702179400.0	22340598.0	EC 2 1.fq.gz	0:150 1:150	A:1816692261;C:1527379142;G:1547365810;T:1810742187;N:0	150	150	1816692261	1527379142	1547365810	1810742187	0	SRX24268111	SRS21034391			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31830	31830	SRR28700417	SRX24268110	SRS21034390	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	EC 1	isolate:EC1\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 1\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	EC 1	EC 1	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		EC_1_1.fq.gz EC_1_2.fq.gz	fastq fastq	6686053500.0	22286845.0	EC 1 1.fq.gz	0:150 1:150	A:1812022780;C:1524359858;G:1544847441;T:1804823421;N:0	150	150	1812022780	1524359858	1544847441	1804823421	0	SRX24268110	SRS21034390			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31831	31831	SRR28700418	SRX24268109	SRS21034388	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	Control 4	isolate:con4\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 4\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	Control 4	Control 4	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		Control_4_1.fq.gz Control_4_2.fq.gz	fastq fastq	6669700500.0	22232335.0	Control 4 1.fq.gz	0:150 1:150	A:1804178265;C:1523547469;G:1543839484;T:1798135282;N:0	150	150	1804178265	1523547469	1543839484	1798135282	0	SRX24268109	SRS21034388			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31832	31832	SRR28700419	SRX24268108	SRS21034387	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	Control 3	isolate:con3\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 3\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	Control 3	Control 3	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		Control_3_1.fq.gz Control_3_2.fq.gz	fastq fastq	6683518800.0	22278396.0	Control 3 1.fq.gz	0:150 1:150	A:1808495506;C:1525725204;G:1545930043;T:1803368047;N:0	150	150	1808495506	1525725204	1545930043	1803368047	0	SRX24268108	SRS21034387			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31833	31833	SRR28700420	SRX24268107	SRS21034386	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	PN 4	isolate:PN4\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 4\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	PN 4	PN 4	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		PN_4_1.fq.gz PN_4_2.fq.gz	fastq fastq	6649316100.0	22164387.0	PN 4 1.fq.gz	0:150 1:150	A:1809816121;C:1508072480;G:1528272654;T:1803154845;N:0	150	150	1809816121	1508072480	1528272654	1803154845	0	SRX24268107	SRS21034386			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31834	31834	SRR28700421	SRX24268106	SRS21034389	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	PN 3	isolate:PN3\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 3\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	PN 3	PN 3	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		PN_3_1.fq.gz PN_3_2.fq.gz	fastq fastq	6616113900.0	22053713.0	PN 3 1.fq.gz	0:150 1:150	A:1802283686;C:1499008018;G:1519150002;T:1795672194;N:0	150	150	1802283686	1499008018	1519150002	1795672194	0	SRX24268106	SRS21034389			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31835	31835	SRR28700422	SRX24268105	SRS21034385	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	Control 2	isolate:con2\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 2\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	Control 2	Control 2	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		Control_2_1.fq.gz Control_2_2.fq.gz	fastq fastq	6701719200.0	22339064.0	Control 2 1.fq.gz	0:150 1:150	A:1812352260;C:1531672703;G:1551377072;T:1806317165;N:0	150	150	1812352260	1531672703	1551377072	1806317165	0	SRX24268105	SRS21034385			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
31836	31836	SRR28700423	SRX24268104	SRS21034384	SRP501894	PRJNA1100624	Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis	PRJNA1100624	Other	Research indicates that Epimedin C EC an active compound in Epimedium offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization increases bone mass and improves bone density thus mitigating bone tissue damage caused by prednisolone. Additionally EC impacts key signaling pathways related to bone development such as osteoclast differentiation estrogen MAPK insulin resistance PPAR and AMPK pathways. This study highlights EC's role in bone health and its promising osteoprotective effects presenting it as a viable cost effective treatment for GIOP.	Control 1	isolate:con1\|age:9dpf\|collection date:2023 07 13\|geo loc name:China:Hubei Xiangyang\|sex:not collected\|tissue:animal sample\|replicate:replicate = biological replicate 1\|BioSampleModel:Model organism or animal	RNA Seq of zebrafish	Control 1	Control 1	Total RNA undergoes mRNA enrichment reverse transcription adapter ligation PCR amplification and circularization into a single stranded DNA library.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP501894		Control_1_1.fq.gz Control_1_2.fq.gz	fastq fastq	6720214500.0	22400715.0	Control 1 1.fq.gz	0:150 1:150	A:1814883015;C:1537948710;G:1559376116;T:1808006659;N:0	150	150	1814883015	1537948710	1559376116	1808006659	0	SRX24268104	SRS21034384			Xiangyang No.1 People's Hospital, Hubei University of Medicine							B	B	biological fallback assumption	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2024-04-15	Larval	Larval	Undetermined	Undetermined
55643	55643	SRR10604044	SRX7283593	SRS5777402	SRP235014	PRJNA594101	Danio rerio Transcriptome	PRJNA594101	Other	Danio rerio Transcriptome post cGAS and STING knockout	stko2	strain:not collected\|isolate:sting knockout 2\|breed:not applicable\|cultivar:not applicable\|ecotype:not applicable\|age:7 days\|dev stage:larvae\|sex:not applicable\|tissue:larvae\|biomaterial provider:Yang xiaojun\|BioSampleModel:Model organism or animal	RNA Seq of zebraish larvae	sting knockout 2	sting knockout 2	RNA seq	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP235014		stko2_1.fastq.gz stko2_2.fastq.gz	fastq fastq	10635609300.0	70904062.0	stko2 1.fastq.gz	0:150 1:150	A:2864931942;C:2450585568;G:2436540783;T:2882828480;N:722527	150	150	2864931942	2450585568	2436540783	2882828480	722527	SRX7283593	SRS5777402	SRA1007465	Shantou university medical college\|Neuroscience Center	Shantou university medical college	1	0.93079	0.07849	0.70301	0.47872	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2019-12-08	Larval	Larval	Undetermined	Undetermined
55644	55644	SRR10604045	SRX7283592	SRS5777401	SRP235014	PRJNA594101	Danio rerio Transcriptome	PRJNA594101	Other	Danio rerio Transcriptome post cGAS and STING knockout	stko1	strain:not collected\|isolate:sting knockout 1\|breed:not applicable\|cultivar:not applicable\|ecotype:not applicable\|age:7 days\|dev stage:larvae\|sex:not applicable\|tissue:larvae\|biomaterial provider:Yang xiaojun\|BioSampleModel:Model organism or animal	RNA Seq of zebraish larvae	sting knockout 1	sting knockout 1	RNA seq	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP235014		stko1_1.fastq.gz stko1_2.fastq.gz	fastq fastq	10453959000.0	69693060.0	stko1 1.fastq.gz	0:150 1:150	A:2823253748;C:2400078679;G:2379662427;T:2850274552;N:689594	150	150	2823253748	2400078679	2379662427	2850274552	689594	SRX7283592	SRS5777401	SRA1007465	Shantou university medical college\|Neuroscience Center	Shantou university medical college	1	0.92736	0.08475	0.69822	0.47233	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2019-12-08	Larval	Larval	Undetermined	Undetermined
55645	55645	SRR10604046	SRX7283591	SRS5777400	SRP235014	PRJNA594101	Danio rerio Transcriptome	PRJNA594101	Other	Danio rerio Transcriptome post cGAS and STING knockout	cgko2	strain:not collected\|isolate:cgas knockout 2\|breed:not applicable\|cultivar:not applicable\|ecotype:not applicable\|age:7 days\|dev stage:larvae\|sex:not applicable\|tissue:larvae\|biomaterial provider:Yang xiaojun\|BioSampleModel:Model organism or animal	RNA Seq of zebraish larvae	cgas knockout 2	cgas knockout 2	RNA seq	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP235014		cgko2_1.fastq.gz cgko2_2.fastq.gz	fastq fastq	10462236900.0	69748246.0	cgko2 1.fastq.gz	0:150 1:150	A:2836737922;C:2388112649;G:2370425883;T:2866326601;N:633845	150	150	2836737922	2388112649	2370425883	2866326601	633845	SRX7283591	SRS5777400	SRA1007465	Shantou university medical college\|Neuroscience Center	Shantou university medical college	1	0.93603	0.10606	0.67765	0.46153	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2019-12-08	Larval	Larval	Undetermined	Undetermined
55646	55646	SRR10604047	SRX7283590	SRS5777399	SRP235014	PRJNA594101	Danio rerio Transcriptome	PRJNA594101	Other	Danio rerio Transcriptome post cGAS and STING knockout	cgko1	strain:not collected\|isolate:cgas knockout 1\|breed:not applicable\|cultivar:not applicable\|ecotype:not applicable\|age:7 days\|dev stage:larvae\|sex:not applicable\|tissue:larvae\|biomaterial provider:Yang xiaojun\|BioSampleModel:Model organism or animal	RNA Seq of zebraish larvae	cgas knockout 1	cgas knockout 1	RNA seq	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP235014		cgko1_2.fastq.gz cgko1_1.fastq.gz	fastq fastq	10498495500.0	69989970.0	cgko1 1.fastq.gz	0:150 1:150	A:2845684832;C:2398817161;G:2379300746;T:2874108573;N:584188	150	150	2845684832	2398817161	2379300746	2874108573	584188	SRX7283590	SRS5777399	SRA1007465	Shantou university medical college\|Neuroscience Center	Shantou university medical college	1	0.93684	0.10589	0.67933	0.48363	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2019-12-08	Larval	Larval	Undetermined	Undetermined
55647	55647	SRR10604048	SRX7283589	SRS5777398	SRP235014	PRJNA594101	Danio rerio Transcriptome	PRJNA594101	Other	Danio rerio Transcriptome post cGAS and STING knockout	wt2	strain:not collected\|isolate:normal 2\|breed:not applicable\|cultivar:not applicable\|ecotype:not applicable\|age:7 days\|dev stage:larvae\|sex:not applicable\|tissue:larvae\|biomaterial provider:Yang xiaojun\|BioSampleModel:Model organism or animal	RNA Seq of zebraish larvae	wt normal 2	wt normal 2	RNA seq	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP235014		wt2_1.fastq.gz wt2_2.fastq.gz	fastq fastq	10660916400.0	71072776.0	wt2 1.fastq.gz	0:150 1:150	A:2906473511;C:2417423798;G:2405111864;T:2931146507;N:760720	150	150	2906473511	2417423798	2405111864	2931146507	760720	SRX7283589	SRS5777398	SRA1007465	Shantou university medical college\|Neuroscience Center	Shantou university medical college	1	0.94167	0.11781	0.66831	0.4757	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2019-12-08	Larval	Larval	Undetermined	Undetermined
55648	55648	SRR10604049	SRX7283588	SRS5777397	SRP235014	PRJNA594101	Danio rerio Transcriptome	PRJNA594101	Other	Danio rerio Transcriptome post cGAS and STING knockout	wt1	strain:not collected\|isolate:normal 1\|breed:not applicable\|cultivar:not applicable\|ecotype:not applicable\|age:7 days\|dev stage:larvae\|sex:not applicable\|tissue:larvae\|biomaterial provider:Yang xiaojun\|BioSampleModel:Model organism or animal	RNA Seq of zebraish larvae	wt nomal 1	wt nomal 1	RNA seq	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP235014		wt1_1.fastq.gz wt1_2.fastq.gz	fastq fastq	10599804000.0	70665360.0	wt1 1.fastq.gz	0:150 1:150	A:2896989124;C:2397285811;G:2382705623;T:2922067937;N:755505	150	150	2896989124	2397285811	2382705623	2922067937	755505	SRX7283588	SRS5777397	SRA1007465	Shantou university medical college\|Neuroscience Center	Shantou university medical college	1	0.93947	0.11723	0.67203	0.45826	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2019-12-08	Larval	Larval	Undetermined	Undetermined
66964	66964	SRR16965143	SRX13156592	SRS11088496	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:10 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :mixture group	mix 1	mix 1	96hpf zebrafish larvae mixture group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		mix2_1_2.fq.gz	fastq	3313823250.0	22092155.0	mix2 1 2.fq.gz	0:0 1:150	A:895726357;C:763402657;G:745765587;T:908922686;N:5963	0	150	895726357	763402657	745765587	908922686	5963	SRX13156592	SRS11088496	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.93604	0.10794	0.65587	0.47956	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66965	66965	SRR16965144	SRX13156591	SRS11088495	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3enf	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:9 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :enrofloxacin group	enf 3	enf 3	96hpf zebrafish larvae enrofloxacin group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		enf_3.fq.gz	fastq	3304972350.0	22033149.0	enf 3.fq.gz	0:150 1:0	A:899427202;C:745999066;G:759917309;T:899625137;N:3636	150	0	899427202	745999066	759917309	899625137	3636	SRX13156591	SRS11088495	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94353	0.10795	0.66212	0.47773	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66966	66966	SRR16965145	SRX13156590	SRS11088493	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1enf	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:7 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :enrofloxacin group	enf 1	enf 1	96hpf zebrafish larvae enrofloxacin group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP346547		enf_1.fq.gz enf_2.fq.gz	fastq fastq	6652389300.0	44349262.0	enf 1.fq.gz	0:150 1:150	A:1759651033;C:1563446116;G:1556912596;T:1772370048;N:9507	150	150	1759651033	1563446116	1556912596	1772370048	9507	SRX13156590	SRS11088493	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94992	0.06316	0.66979	0.48987	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66967	66967	SRR16965146	SRX13156589	SRS11088492	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3car	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:6 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :carbendazim group	car 3	car 3	96hpf zebrafish larvae carbendazim group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		car_3_1.fq.gz	fastq	3335622150.0	22237481.0	car 3 1.fq.gz	0:150 1:0	A:853229671;C:807433601;G:820478265;T:854475092;N:5521	150	0	853229671	807433601	820478265	854475092	5521	SRX13156589	SRS11088492	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.96567	0.03093	0.70997	0.47751	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66968	66968	SRR16965147	SRX13156588	SRS11088494	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1car	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:4 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :carbendazim group	car 1	car 1	96hpf zebrafish larvae carbendazim group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		car_1_1.fq.gz	fastq	3378056400.0	22520376.0	car 1 1.fq.gz	0:150 1:0	A:886009175;C:795203398;G:809447342;T:887390300;N:6185	150	0	886009175	795203398	809447342	887390300	6185	SRX13156588	SRS11088494	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95701	0.05956	0.67836	0.4884	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66969	66969	SRR16965148	SRX13156587	SRS11088491	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:3 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :control group	con 3	con 3	96hpf zebrafish larvae control group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		con_3_2.fq.gz	fastq	3359054500.0	33590545.0	con 3 2.fq.gz	0:100 1:0	A:914533337;C:755914202;G:773676246;T:914930715;N:0	100	0	914533337	755914202	773676246	914930715	0	SRX13156587	SRS11088491	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95076	0.10478	0.65646	0.49594	100	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66970	66970	SRR16965149	SRX13156586	SRS11088489	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:12 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :mixture group	mix 3	mix 3	96hpf zebrafish larvae mixture group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		mix2_3_1.fq.gz	fastq	3362094000.0	33620940.0	mix2 3 1.fq.gz	0:100 1:0	A:916124379;C:755910593;G:768246534;T:921812494;N:0	100	0	916124379	755910593	768246534	921812494	0	SRX13156586	SRS11088489	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94894	0.10416	0.65342	0.49475	100	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66971	66971	SRR16965150	SRX13156585	SRS11088490	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	2mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:11 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :mixture group	mix 2	mix 2	96hpf zebrafish larvae mixture group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP346547		car_2_2.fq.gz mix2_2_1.fq.gz	fastq fastq	6669719100.0	44464794.0	car 2 2.fq.gz	0:150 1:150	A:1815824677;C:1515086864;G:1506360115;T:1832433148;N:14296	150	150	1815824677	1515086864	1506360115	1832433148	14296	SRX13156585	SRS11088490	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.93884	0.11657	0.65527	0.48114	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66972	66972	SRR16965151	SRX13156584	SRS11088488	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	2con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:2 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :control group	con 2	con 2	96hpf zebrafish larvae control group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547	loader:fastq load.py	con_2_2.fq	fastq	3324287550.0	22161917.0	con 2 2.fq.gz	0:150	A:848766265;C:812477645;G:798995610;T:864040426;N:7604	150		848766265	812477645	798995610	864040426	7604	SRX13156584	SRS11088488	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95546	0.03524	0.70027	0.48649	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-22	Larval	Larval	Undetermined	Undetermined
66973	66973	SRR16965152	SRX13156583	SRS11088487	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:1 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :control group	con 1	con 1	96hpf zebrafish larvae control group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547	loader:fastq load.py	con_1_1.fq	fastq	3330724500.0	22204830.0	con 1 1.fq.gz	0:150	A:896812508;C:762246067;G:774062043;T:897597946;N:5936	150		896812508	762246067	774062043	897597946	5936	SRX13156583	SRS11088487	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94926	0.08711	0.66789	0.48628	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-22	Larval	Larval	Undetermined	Undetermined
66974	66974	SRR16959538	SRX13151074	SRS11083380	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1+mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:10 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : mixture group	mix 1	mix 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP346418		mix1_3_2.fq.gz mix1_1_1.fq.gz	fastq fastq	6639699600.0	44264664.0	mix1 1 1.fq.gz	0:150 1:150	A:1738687157;C:1575344731;G:1569683716;T:1755974708;N:9288	150	150	1738687157	1575344731	1569683716	1755974708	9288	SRX13151074	SRS11083380	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95161	0.05697	0.6817	0.48485	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66975	66975	SRR16959539	SRX13151073	SRS11083379	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2dim	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:8 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : dimethomorph group	dim 2	dim 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dim_2_1.fq.gz	fastq	3344257500.0	22295050.0	dim 2 1.fq.gz	0:150 1:0	A:895700119;C:767415749;G:784994320;T:896143585;N:3727	150	0	895700119	767415749	784994320	896143585	3727	SRX13151073	SRS11083379	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.9497	0.08418	0.66352	0.49341	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66976	66976	SRR16959540	SRX13151072	SRS11083378	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1dim	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:7 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : dimethomorph group	dim 1	dim 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dim_1_1.fq.gz	fastq	3318812250.0	22125415.0	dim 1 1.fq.gz	0:150 1:0	A:908481293;C:742787936;G:755930542;T:911608821;N:3658	150	0	908481293	742787936	755930542	911608821	3658	SRX13151072	SRS11083378	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94211	0.11824	0.65344	0.47716	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66977	66977	SRR16959541	SRX13151071	SRS11083377	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	3dif	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:6 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : difenoconazole group	dif 3	dif 3	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dif_3_1.fq.gz	fastq	3318453000.0	22123020.0	dif 3 1.fq.gz	0:150 1:0	A:893975607;C:758489621;G:772391705;T:893592335;N:3732	150	0	893975607	758489621	772391705	893592335	3732	SRX13151071	SRS11083377	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94838	0.08393	0.66543	0.4818	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66978	66978	SRR16959542	SRX13151070	SRS11083376	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2dif	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:5 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : difenoconazole group	dif 2	dif 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dif_2_2.fq.gz	fastq	3304972350.0	22033149.0	dif 2 2.fq.gz	0:0 1:150	A:890456734;C:764917766;G:744757536;T:904833787;N:6527	0	150	890456734	764917766	744757536	904833787	6527	SRX13151070	SRS11083376	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.93514	0.107	0.6633	0.47599	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66979	66979	SRR16959543	SRX13151069	SRS11083375	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1dif	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:4 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : difenoconazole group	dif 1	dif 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dif_1_1.fq.gz	fastq	3295443900.0	21969626.0	dif 1 1.fq.gz	0:150 1:0	A:887936493;C:751636494;G:765508757;T:890358629;N:3527	150	0	887936493	751636494	765508757	890358629	3527	SRX13151069	SRS11083375	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94623	0.09138	0.66478	0.4828	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66980	66980	SRR16959544	SRX13151068	SRS11083374	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	3+con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:3 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : control group	con 3	con 3	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		con_3_1.fq.gz	fastq	3306406800.0	22042712.0	con 3 1.fq.gz	0:150 1:0	A:872740236;C:773482184;G:788334419;T:871846539;N:3422	150	0	872740236	773482184	788334419	871846539	3422	SRX13151068	SRS11083374	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95458	0.06103	0.67409	0.48439	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66981	66981	SRR16959545	SRX13151067	SRS11083373	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2+mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:11 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : mixture group	mix 2	mix 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP346418		mix1_2_1.fq.gz dim_3_2.fq.gz	fastq fastq	6589866900.0	43932446.0	dim 3 2.fq.gz	0:150 1:150	A:1782755416;C:1508342477;G:1501934674;T:1796820276;N:14057	150	150	1782755416	1508342477	1501934674	1796820276	14057	SRX13151067	SRS11083373	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.93861	0.10685	0.66393	0.47194	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66982	66982	SRR16959546	SRX13151066	SRS11083372	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2+con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:2 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : control group	con 2	con 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		con_2_2.fq.gz	fastq	3324287550.0	22161917.0	con 2 2.fq.gz	0:0 1:150	A:848766265;C:812477645;G:798995610;T:864040426;N:7604	0	150	848766265	812477645	798995610	864040426	7604	SRX13151066	SRS11083372	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95548	0.03524	0.70021	0.4867	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66983	66983	SRR16959547	SRX13151065	SRS11083371	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1+con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:1 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : control group	con 1	con 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		con_1_1.fq.gz	fastq	3330724500.0	22204830.0	con 1 1.fq.gz	0:150 1:0	A:896812508;C:762246067;G:774062043;T:897597946;N:5936	150	0	896812508	762246067	774062043	897597946	5936	SRX13151065	SRS11083371	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94925	0.08711	0.66772	0.48635	150	B		usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined

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CREATE TABLE run_metadata("run.accession" VARCHAR, "experiment.accession" VARCHAR, "sample.accession" VARCHAR, "study.accession" VARCHAR, bioproject VARCHAR, "study.title" VARCHAR, "study.alias" VARCHAR, "study.type" VARCHAR, "study.abstract" VARCHAR, "study.attributes" VARCHAR, "study.PMIDs" VARCHAR, "sample.description" VARCHAR, "sample.title" VARCHAR, "sample.alias" VARCHAR, "sample.centername" VARCHAR, "sample.attributes" VARCHAR, "GEOsample.title" VARCHAR, "GEOsample.dataprocessing" VARCHAR, "GEOsample.source" VARCHAR, "GEOsample.treatmentprotocol" VARCHAR, "GEOsample.extractprotocol" VARCHAR, "GEOsample.growthprotocol" VARCHAR, "GEOsample.characteristics" VARCHAR, "GEOsample.accession" VARCHAR, "experiment.title" VARCHAR, "experiment.alias" VARCHAR, "experiment.library_name" VARCHAR, "experiment.design_description" VARCHAR, "experiment.library_construction_protocol" VARCHAR, "experiment.attributes" VARCHAR, "experiment.library_strategy" VARCHAR, "experiment.library_source" VARCHAR, "experiment.library_selection" VARCHAR, "experiment.library_layout" VARCHAR, "experiment.platform" VARCHAR, "experiment.instrument_model" VARCHAR, "experiment.spot_descriptor" VARCHAR, "experiment.study_ref" VARCHAR, "run.title" VARCHAR, "run.attributes" VARCHAR, "run.filename" VARCHAR, "run.semantic_name" VARCHAR, "run.total_bases" DOUBLE, "run.total_spots" DOUBLE, "run.alias" VARCHAR, "run.read_lengths" VARCHAR, "run.base_counts" VARCHAR, "run.r1_length" BIGINT, "run.r2_length" BIGINT, "run.r3_length" BIGINT, "run.r4_length" BIGINT, "run.Acount" BIGINT, "run.Ccount" BIGINT, "run.Gcount" BIGINT, "run.Tcount" BIGINT, "run.Ncount" BIGINT, "run.experiment" VARCHAR, "run.pool_member" VARCHAR, "submission.accession" VARCHAR, "submission.srasource" VARCHAR, "submission.bioprojectsource" VARCHAR, "seqdetective.n_mates" BIGINT, "seqdetective.mapping_rate.mate1" DOUBLE, "seqdetective.mapping_rate.mate2" DOUBLE, "seqdetective.nofeature_rate.mate1" DOUBLE, "seqdetective.nofeature_rate.mate2" DOUBLE, "seqdetective.sparsity.mate1" DOUBLE, "seqdetective.sparsity.mate2" DOUBLE, "seqdetective.pos_strand_rate.mate1" DOUBLE, "seqdetective.pos_strand_rate.mate2" DOUBLE, "seqdetective.readlen.mate1" BIGINT, "seqdetective.readlen.mate2" BIGINT, "seqdetective.judgement.mate1" VARCHAR, "seqdetective.judgement.mate2" VARCHAR, "seqdetective.judgement.reason" VARCHAR, platform_family VARCHAR, instrument_generation VARCHAR, read_bias VARCHAR, selection_class VARCHAR, prep_kit VARCHAR, sc_or_bulk VARCHAR, tech_class VARCHAR, technology VARCHAR, tech_variant VARCHAR, "submission.bioprojectsource.country" VARCHAR, earliest_date DATE, devstage_curation VARCHAR, devstage_curation_coarse VARCHAR, tissue_curation VARCHAR, tissue_curation_coarse VARCHAR);;
CREATE INDEX idx_run_bioproject ON run_metadata(bioproject);;
CREATE INDEX idx_run_run_accession ON run_metadata("run.accession");;