metadata: run_metadata: 27 rows where experiment.library_selection = "Oligo-dT", experiment.platform = "BGISEQ" and tissue_curation

27 rows where experiment.library_selection = "Oligo-dT", experiment.platform = "BGISEQ" and tissue_curation_coarse = "Nervous System"

descending

Link	rowid ▼	run.accession	experiment.accession	sample.accession	study.accession	bioproject	study.title	study.alias	study.type	study.abstract	sample.description	sample.alias	sample.attributes	experiment.title	experiment.alias	experiment.library_name	experiment.design_description	experiment.library_strategy	experiment.library_source	experiment.library_selection	experiment.library_layout	experiment.platform	experiment.instrument_model	experiment.study_ref	run.filename	run.semantic_name	run.total_bases	run.total_spots	run.alias	run.read_lengths	run.base_counts	run.r1_length	run.r2_length	run.Acount	run.Ccount	run.Gcount	run.Tcount	run.Ncount	run.experiment	run.pool_member	submission.accession	submission.srasource	submission.bioprojectsource	seqdetective.n_mates	seqdetective.mapping_rate.mate1	seqdetective.nofeature_rate.mate1	seqdetective.sparsity.mate1	seqdetective.pos_strand_rate.mate1	seqdetective.readlen.mate1	seqdetective.judgement.mate1	seqdetective.judgement.reason	platform_family	instrument_generation	read_bias	selection_class	prep_kit	sc_or_bulk	tech_class	technology	submission.bioprojectsource.country	earliest_date	devstage_curation	devstage_curation_coarse	tissue_curation	tissue_curation_coarse
57271	57271	SRR12577970	SRX9064853	SRS7314026	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ctrl 3 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 6'\|BioSampleModel:Model organism or animal	Ctrl 3 zebrafish	Ctrl 3 zebrafish	Ctrl 3 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ctrl_3_1.fq.gz	fastq	1061227250.0	21224545.0	Ctrl 3 1.fq.gz	0:50	A:286099732;C:241244619;G:246876865;T:287006034;N:0	50		286099732	241244619	246876865	287006034	0	SRX9064853	SRS7314026	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94563	0.10453	0.70552	0.46655	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57272	57272	SRR12577971	SRX9064852	SRS7314025	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ctrl 2 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 5 prime\|BioSampleModel:Model organism or animal	Ctrl 2 zebrafish	Ctrl 2 zebrafish	Ctrl 2 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ctrl_2_1.fq.gz	fastq	1058116700.0	21162334.0	Ctrl 2 1.fq.gz	0:50	A:287223905;C:238707750;G:244987559;T:287197486;N:0	50		287223905	238707750	244987559	287197486	0	SRX9064852	SRS7314025	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94534	0.11174	0.70104	0.47946	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57273	57273	SRR12577972	SRX9064851	SRS7314024	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ctrl 1 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 4'\|BioSampleModel:Model organism or animal	Ctrl 1 zebrafish	Ctrl 1 zebrafish	Ctrl 1 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ctrl_1_1.fq.gz	fastq	1065919600.0	21318392.0	Ctrl 1 1.fq.gz	0:50	A:295920720;C:242146677;G:242962633;T:284889570;N:0	50		295920720	242146677	242962633	284889570	0	SRX9064851	SRS7314024	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94228	0.15007	0.68028	0.46845	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57274	57274	SRR12577973	SRX9064850	SRS7314023	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ator STS 3 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 3 prime\|BioSampleModel:Model organism or animal	Ator STS 3 zebrafish	Ator STS 3 zebrafish	Ator STS 3 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ator_STS_3_1.fq.gz	fastq	1059717350.0	21194347.0	Ator STS 3 1.fq.gz	0:50	A:287279590;C:239708340;G:245740313;T:286989107;N:0	50		287279590	239708340	245740313	286989107	0	SRX9064850	SRS7314023	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94345	0.10458	0.69686	0.4755	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57275	57275	SRR12577974	SRX9064849	SRS7314022	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ator STS 2 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 2'\|BioSampleModel:Model organism or animal	Ator STS 2 zebrafish	Ator STS 2 zebrafish	Ator STS 2 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ator_STS_2_1.fq.gz	fastq	1057950250.0	21159005.0	Ator STS 2 1.fq.gz	0:50	A:286256354;C:238832868;G:244078781;T:288782247;N:0	50		286256354	238832868	244078781	288782247	0	SRX9064849	SRS7314022	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94307	0.10974	0.69631	0.4703	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57276	57276	SRR12577975	SRX9064848	SRS7314021	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ator STS 1 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 1'\|BioSampleModel:Model organism or animal	Ator STS 1 zebrafish	Ator STS 1 zebrafish	Ator STS 1 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ator_STS_1_1.fq.gz	fastq	1070136700.0	21402734.0	Ator STS 1 1.fq.gz	0:50	A:297601042;C:243837062;G:243583907;T:285114689;N:0	50		297601042	243837062	243583907	285114689	0	SRX9064848	SRS7314021	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94665	0.12219	0.67953	0.46393	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57277	57277	SRR12577976	SRX9064847	SRS7314020	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ator 3 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 3 prime\|BioSampleModel:Model organism or animal	Ator 3 zebrafish	Ator 3 zebrafish	Ator 3 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ator_3_1.fq.gz	fastq	1058031900.0	21160638.0	Ator 3 1.fq.gz	0:50	A:285399527;C:239993172;G:245571467;T:287067734;N:0	50		285399527	239993172	245571467	287067734	0	SRX9064847	SRS7314020	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94536	0.11052	0.6957	0.48195	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57278	57278	SRR12577977	SRX9064846	SRS7314019	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ator 2 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 2'\|BioSampleModel:Model organism or animal	Ator 2 zebrafish	Ator 2 zebrafish	Ator 2 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ator_2_1.fq.gz	fastq	1059618400.0	21192368.0	Ator 2 1.fq.gz	0:50	A:283429136;C:243023053;G:248904818;T:284261393;N:0	50		283429136	243023053	248904818	284261393	0	SRX9064846	SRS7314019	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94743	0.09493	0.70218	0.475	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
57279	57279	SRR12577978	SRX9064845	SRS7314018	SRP279881	PRJNA612371	Danio rerio strain:TU Raw sequence reads	PRJNA612371	Whole Genome Sequencing	Hemorrhage stroke is a severe vascular disease of the brain with a high mortality rate in humans. Sodium tanshinone IIA sulfonate STS is a water soluble derivative of tanshinone IIA which is the main active ingredient of Salvia miltiorrhiza Bge known as Danshen in Chinese and has been approved as a commercial drug for treating cardiovascular disease by the China Food and Drug Administration. In our previous study we established a HMG COA inhibitor atorvastatin Ator induced zebrafish model of cerebral hemorrhage and found that STS dramatically decreased both the hemorrhage rate and hemorrhage area although the underlying mechanism was not fully elucidated. Therefore in the present study we conducted transcriptome analysis of the protective effect of STS against Ator induced cerebral hemorrhage in zebrafish using RNA Seq technology and further clarify its underlying molecular mechanisms on HIF 1 and its regulators i.e. the PI3K/Akt and MAPK signaling pathways were verified by real time PCR analysis and specific pharmacological inhibitors. We are also able to show that hemoglobin carbonic anhydrase Na+/H+ exchanger and HIF 1 genes might be potential biomarkers of Ator induced cerebral hemorrhage in zebrafish as well as pharmacological targets of STS. This study also provided evidence of bio markers involved in hemorrhage stroke and improved understanding of the effects of HMG COA inhibition on vascular permeability and cerebral hemorrhage.		Ator 1 zebrafish	strain:TU\|isolate:not collected\|breed:not collected\|cultivar:not collected\|ecotype:not collected\|age:2dpf\|dev stage:not collected\|sex:not applicable\|tissue:head\|geo loc name:China:Shanghai\|sample type:model organism\|replicate:replicate=biological replicate 1'\|BioSampleModel:Model organism or animal	Ator 1 zebrafish	Ator 1 zebrafish	Ator 1 zebrafish	transcriptome	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP279881	Ator_1_1.fq.gz	fastq	1075695950.0	21513919.0	Ator 1 1.fq.gz	0:50	A:297768036;C:244470267;G:243768925;T:289688722;N:0	50		297768036	244470267	243768925	289688722	0	SRX9064845	SRS7314018	SRA1120721	Shanghai University of Traditional Chinese Medicine\|Longhua Hospital	Shanghai University of Traditional Chinese Medicine	1	0.94468	0.13183	0.68363	0.46288	50	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2020-09-03	Hatching	Embryo	Head	Nervous System
65944	65944	SRR15700565	SRX11996477	SRS10003992	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	R01	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 1\|treatment:control\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	R01	R01	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	R01_1.fq.gz R01_2.fq.gz	fastq fastq	6781182900.0	45207886.0	R01 1.fq.gz	0:150 1:150	A:1988991157;C:1393829563;G:1402027963;T:1996312981;N:21236	150	150	1988991157	1393829563	1402027963	1996312981	21236	SRX11996477	SRS10003992	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91278	0.20165	0.71054	0.54354	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65945	65945	SRR15700566	SRX11996476	SRS10003991	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	EH3	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 3\|treatment:AMI 40.0\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	EH3	EH3	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	EH3_1.fq.gz EH3_2.fq.gz	fastq fastq	6798939900.0	45326266.0	EH3 1.fq.gz	0:150 1:150	A:1958992563;C:1429773625;G:1441958341;T:1968192397;N:22974	150	150	1958992563	1429773625	1441958341	1968192397	22974	SRX11996476	SRS10003991	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91681	0.18245	0.7083	0.5369	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65946	65946	SRR15700567	SRX11996475	SRS10003990	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	EH2	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 2\|treatment:AMI 40.0\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	EH2	EH2	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	EH2_1.fq.gz EH2_2.fq.gz	fastq fastq	6792825900.0	45285506.0	EH2 1.fq.gz	0:150 1:150	A:1958355652;C:1427389031;G:1440081079;T:1966978334;N:21804	150	150	1958355652	1427389031	1440081079	1966978334	21804	SRX11996475	SRS10003990	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91907	0.17888	0.70575	0.54118	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65947	65947	SRR15700568	SRX11996474	SRS10003989	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	EH1	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 1\|treatment:AMI 40.0\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	EH1	EH1	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	EH1_1.fq.gz EH1_2.fq.gz	fastq fastq	6723154200.0	44821028.0	EH1 1.fq.gz	0:150 1:150	A:1939940725;C:1412087358;G:1424339686;T:1946764075;N:22356	150	150	1939940725	1412087358	1424339686	1946764075	22356	SRX11996474	SRS10003989	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91848	0.1756	0.71293	0.54795	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65948	65948	SRR15700569	SRX11996473	SRS10003988	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	EL3	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 3\|treatment:AMI 2.5\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	EL3	EL3	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	EL3_1.fq.gz EL3_2.fq.gz	fastq fastq	6756746700.0	45044978.0	EL3 1.fq.gz	0:150 1:150	A:1958754520;C:1411572406;G:1418753117;T:1967647023;N:19634	150	150	1958754520	1411572406	1418753117	1967647023	19634	SRX11996473	SRS10003988	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91873	0.18319	0.71027	0.55277	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65949	65949	SRR15700570	SRX11996472	SRS10003987	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	EL2	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 2\|treatment:AMI 2.5\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	EL2	EL2	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	EL2_1.fq.gz EL2_2.fq.gz	fastq fastq	6811200600.0	45408004.0	EL2 1.fq.gz	0:150 1:150	A:1961542081;C:1433135536;G:1446857456;T:1969644200;N:21327	150	150	1961542081	1433135536	1446857456	1969644200	21327	SRX11996472	SRS10003987	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91853	0.17639	0.71076	0.54175	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65950	65950	SRR15700571	SRX11996471	SRS10003986	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	EL1	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 1\|treatment:AMI 2.5\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	EL1	EL1	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	EL1_1.fq.gz EL1_2.fq.gz	fastq fastq	6764302200.0	45095348.0	EL1 1.fq.gz	0:150 1:150	A:1943560425;C:1428175041;G:1441358638;T:1951185256;N:22840	150	150	1943560425	1428175041	1441358638	1951185256	22840	SRX11996471	SRS10003986	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91885	0.17456	0.71423	0.53356	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65951	65951	SRR15700572	SRX11996470	SRS10003985	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	E03	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 3\|treatment:control\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	E03	E03	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	E03_1.fq.gz E03_2.fq.gz	fastq fastq	6762334500.0	45082230.0	E03 1.fq.gz	0:150 1:150	A:1941432663;C:1429093210;G:1444693949;T:1947091388;N:23290	150	150	1941432663	1429093210	1444693949	1947091388	23290	SRX11996470	SRS10003985	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91902	0.17577	0.71413	0.54672	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65952	65952	SRR15700573	SRX11996469	SRS10003984	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	RH3	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 3\|treatment:AMI 40.0\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	RH3	RH3	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	RH3_1.fq.gz RH3_2.fq.gz	fastq fastq	6620159400.0	44134396.0	RH3 1.fq.gz	0:150 1:150	A:1906961918;C:1396128146;G:1402603611;T:1914452217;N:13508	150	150	1906961918	1396128146	1402603611	1914452217	13508	SRX11996469	SRS10003984	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91596	0.18007	0.70307	0.53072	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65953	65953	SRR15700574	SRX11996468	SRS10003983	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	RH2	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 2\|treatment:AMI 40.0\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	RH2	RH2	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	RH2_1.fq.gz RH2_2.fq.gz	fastq fastq	6779957400.0	45199716.0	RH2 1.fq.gz	0:150 1:150	A:1943750299;C:1436936087;G:1447253724;T:1952003667;N:13623	150	150	1943750299	1436936087	1447253724	1952003667	13623	SRX11996468	SRS10003983	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91806	0.17416	0.70364	0.53449	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65954	65954	SRR15700575	SRX11996467	SRS10003982	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	RH1	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 1\|treatment:AMI 40.0\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	RH1	RH1	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	RH1_1.fq.gz RH1_2.fq.gz	fastq fastq	6803711400.0	45358076.0	RH1 1.fq.gz	0:150 1:150	A:1919109429;C:1472916047;G:1485344758;T:1926327627;N:13539	150	150	1919109429	1472916047	1485344758	1926327627	13539	SRX11996467	SRS10003982	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.92595	0.14064	0.71392	0.5508	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65955	65955	SRR15700576	SRX11996466	SRS10003981	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	RL3	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 3\|treatment:AMI 2.5\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	RL3	RL3	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	RL3_1.fq.gz RL3_2.fq.gz	fastq fastq	6775779300.0	45171862.0	RL3 1.fq.gz	0:150 1:150	A:1977555439;C:1404514814;G:1412262159;T:1981432811;N:14077	150	150	1977555439	1404514814	1412262159	1981432811	14077	SRX11996466	SRS10003981	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91883	0.1833	0.71638	0.55343	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65956	65956	SRR15700577	SRX11996465	SRS10003979	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	RL2	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 2\|treatment:AMI 2.5\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	RL2	RL2	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	RL2_1.fq.gz RL2_2.fq.gz	fastq fastq	6716301900.0	44775346.0	RL2 1.fq.gz	0:150 1:150	A:1959165761;C:1392977724;G:1400724963;T:1963418595;N:14857	150	150	1959165761	1392977724	1400724963	1963418595	14857	SRX11996465	SRS10003979	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.92114	0.18164	0.7217	0.55665	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65957	65957	SRR15700578	SRX11996464	SRS10003980	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	RL1	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 1\|treatment:AMI 2.5\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	RL1	RL1	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	RL1_1.fq.gz RL1_2.fq.gz	fastq fastq	6632905200.0	44219368.0	RL1 1.fq.gz	0:150 1:150	A:1930258593;C:1379056686;G:1391344096;T:1932223405;N:22420	150	150	1930258593	1379056686	1391344096	1932223405	22420	SRX11996464	SRS10003980	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91966	0.18087	0.72121	0.5664	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65958	65958	SRR15700579	SRX11996463	SRS10003978	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	R03	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 3\|treatment:control\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	R03	R03	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	R03_1.fq.gz R03_2.fq.gz	fastq fastq	6574600200.0	43830668.0	R03 1.fq.gz	0:150 1:150	A:1940343461;C:1342685356;G:1350150434;T:1941399481;N:21468	150	150	1940343461	1342685356	1350150434	1941399481	21468	SRX11996463	SRS10003978	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91867	0.19479	0.72707	0.57885	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65959	65959	SRR15700580	SRX11996462	SRS10003977	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 21 DAY RECOVERY	R02	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 2\|treatment:control\|SAMPLING TIME:END OF 21 DAY RECOVERY\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	R02	R02	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	R02_1.fq.gz R02_2.fq.gz	fastq fastq	6399007800.0	42660052.0	R02 1.fq.gz	0:150 1:150	A:1884110766;C:1308008993;G:1315054545;T:1891764364;N:69132	150	150	1884110766	1308008993	1315054545	1891764364	69132	SRX11996462	SRS10003977	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91477	0.19859	0.72417	0.55394	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65960	65960	SRR15700581	SRX11996461	SRS10003976	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	E02	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 2\|treatment:control\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	E02	E02	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	E02_1.fq.gz E02_2.fq.gz	fastq fastq	6588207000.0	43921380.0	E02 1.fq.gz	0:150 1:150	A:1905685715;C:1379753621;G:1389708827;T:1913038146;N:20691	150	150	1905685715	1379753621	1389708827	1913038146	20691	SRX11996461	SRS10003976	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91596	0.18027	0.70903	0.54349	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System
65961	65961	SRR15700582	SRX11996460	SRS10003975	SRP335395	PRJNA759881	Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio	PRJNA759881	Other	Following exposure to Amitriptyline AMI for 7 days E7 zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.	END OF 7 DAY EXPOSURE	E01	strain:AB\|age:4 MONTHS\|dev stage:Adult\|sex:female\|tissue:brain\|replicate:replicate = biological replicate 1\|treatment:control\|SAMPLING TIME:END OF 7 DAY EXPOSURE\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: adult female brain	E01	E01	a standardized procedure at the Beijing Genome Institute	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	PAIRED	BGISEQ	BGISEQ-500	SRP335395	E01_1.fq.gz E01_2.fq.gz	fastq fastq	6766213800.0	45108092.0	E01 1.fq.gz	0:150 1:150	A:1963125745;C:1410900205;G:1420069949;T:1972096961;N:20940	150	150	1963125745	1410900205	1420069949	1972096961	20940	SRX11996460	SRS10003975	SRA1288076	Jiangsu University\|Institute of Environmental Health and Ecological S	Jiangsu University	1	0.91884	0.18555	0.71585	0.5455	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-09-02	Adult	Adult	Brain	Nervous System

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CREATE TABLE run_metadata("run.accession" VARCHAR, "experiment.accession" VARCHAR, "sample.accession" VARCHAR, "study.accession" VARCHAR, bioproject VARCHAR, "study.title" VARCHAR, "study.alias" VARCHAR, "study.type" VARCHAR, "study.abstract" VARCHAR, "study.attributes" VARCHAR, "study.PMIDs" VARCHAR, "sample.description" VARCHAR, "sample.title" VARCHAR, "sample.alias" VARCHAR, "sample.centername" VARCHAR, "sample.attributes" VARCHAR, "GEOsample.title" VARCHAR, "GEOsample.dataprocessing" VARCHAR, "GEOsample.source" VARCHAR, "GEOsample.treatmentprotocol" VARCHAR, "GEOsample.extractprotocol" VARCHAR, "GEOsample.growthprotocol" VARCHAR, "GEOsample.characteristics" VARCHAR, "GEOsample.accession" VARCHAR, "experiment.title" VARCHAR, "experiment.alias" VARCHAR, "experiment.library_name" VARCHAR, "experiment.design_description" VARCHAR, "experiment.library_construction_protocol" VARCHAR, "experiment.attributes" VARCHAR, "experiment.library_strategy" VARCHAR, "experiment.library_source" VARCHAR, "experiment.library_selection" VARCHAR, "experiment.library_layout" VARCHAR, "experiment.platform" VARCHAR, "experiment.instrument_model" VARCHAR, "experiment.spot_descriptor" VARCHAR, "experiment.study_ref" VARCHAR, "run.title" VARCHAR, "run.attributes" VARCHAR, "run.filename" VARCHAR, "run.semantic_name" VARCHAR, "run.total_bases" DOUBLE, "run.total_spots" DOUBLE, "run.alias" VARCHAR, "run.read_lengths" VARCHAR, "run.base_counts" VARCHAR, "run.r1_length" BIGINT, "run.r2_length" BIGINT, "run.r3_length" BIGINT, "run.r4_length" BIGINT, "run.Acount" BIGINT, "run.Ccount" BIGINT, "run.Gcount" BIGINT, "run.Tcount" BIGINT, "run.Ncount" BIGINT, "run.experiment" VARCHAR, "run.pool_member" VARCHAR, "submission.accession" VARCHAR, "submission.srasource" VARCHAR, "submission.bioprojectsource" VARCHAR, "seqdetective.n_mates" BIGINT, "seqdetective.mapping_rate.mate1" DOUBLE, "seqdetective.mapping_rate.mate2" DOUBLE, "seqdetective.nofeature_rate.mate1" DOUBLE, "seqdetective.nofeature_rate.mate2" DOUBLE, "seqdetective.sparsity.mate1" DOUBLE, "seqdetective.sparsity.mate2" DOUBLE, "seqdetective.pos_strand_rate.mate1" DOUBLE, "seqdetective.pos_strand_rate.mate2" DOUBLE, "seqdetective.readlen.mate1" BIGINT, "seqdetective.readlen.mate2" BIGINT, "seqdetective.judgement.mate1" VARCHAR, "seqdetective.judgement.mate2" VARCHAR, "seqdetective.judgement.reason" VARCHAR, platform_family VARCHAR, instrument_generation VARCHAR, read_bias VARCHAR, selection_class VARCHAR, prep_kit VARCHAR, sc_or_bulk VARCHAR, tech_class VARCHAR, technology VARCHAR, tech_variant VARCHAR, "submission.bioprojectsource.country" VARCHAR, earliest_date DATE, devstage_curation VARCHAR, devstage_curation_coarse VARCHAR, tissue_curation VARCHAR, tissue_curation_coarse VARCHAR);;
CREATE INDEX idx_run_bioproject ON run_metadata(bioproject);;
CREATE INDEX idx_run_run_accession ON run_metadata("run.accession");;