metadata: run_metadata: 28 rows where experiment.library_layout = "SINGLE", experiment.platform = "BGISEQ" and tissue_curation

28 rows where experiment.library_layout = "SINGLE", experiment.platform = "BGISEQ" and tissue_curation_coarse = "Undetermined"

descending

Link	rowid ▼	run.accession	experiment.accession	sample.accession	study.accession	bioproject	study.title	study.alias	study.type	study.abstract	sample.alias	sample.attributes	experiment.title	experiment.alias	experiment.library_name	experiment.design_description	experiment.library_strategy	experiment.library_source	experiment.library_selection	experiment.library_layout	experiment.platform	experiment.instrument_model	experiment.study_ref	run.attributes	run.filename	run.semantic_name	run.total_bases	run.total_spots	run.alias	run.read_lengths	run.base_counts	run.r1_length	run.r2_length	run.Acount	run.Ccount	run.Gcount	run.Tcount	run.Ncount	run.experiment	run.pool_member	submission.accession	submission.srasource	submission.bioprojectsource	seqdetective.n_mates	seqdetective.mapping_rate.mate1	seqdetective.nofeature_rate.mate1	seqdetective.sparsity.mate1	seqdetective.pos_strand_rate.mate1	seqdetective.readlen.mate1	seqdetective.judgement.mate1	seqdetective.judgement.reason	platform_family	instrument_generation	read_bias	selection_class	prep_kit	sc_or_bulk	tech_class	technology	submission.bioprojectsource.country	earliest_date	devstage_curation	devstage_curation_coarse	tissue_curation	tissue_curation_coarse
52210	52210	SRR9021058	SRX5799154	SRS4730324	SRP195685	PRJNA541367	Global transcriptomic analysis of zebrafish glucagon receptor mutant	PRJNA541367	Other	We performed RNA sequencing RNA seq analysis of whole fish to provide a comprehensive view of its global transcriptomic regulation in this study.	WT 1	replicate:biological replicate 1\|strain:AB\|age:7 days\|sex:not applicable\|tissue:total\|BioSampleModel:Model organism or animal	Diano rerio transcriptome	WT 1 20190506 1	WT 1 20190506 1	RNA seq of WT Diano rerio	RNA-Seq	TRANSCRIPTOMIC	other	SINGLE	BGISEQ	BGISEQ-500	SRP195685	loader:fastq load.py	WT1.1.fq	fastq	1094498950.0	21889979.0	WT1.1.fq	0:50	A:291195764;C:255539280;G:262638316;T:284737693;N:387897	50		291195764	255539280	262638316	284737693	387897	SRX5799154	SRS4730324	SRA883435	Xiamen University\|School of Pharmaceutical Sciences	Xiamen University	1	0.94195	0.09713	0.66689	0.47749	50	B	usable mapping rate	bgi	bgi	unknown	random_priming	unknown	bulk	unknown	unknown	China	2020-01-18	Larval	Larval	Undetermined	Undetermined
52211	52211	SRR9021059	SRX5799153	SRS4730323	SRP195685	PRJNA541367	Global transcriptomic analysis of zebrafish glucagon receptor mutant	PRJNA541367	Other	We performed RNA sequencing RNA seq analysis of whole fish to provide a comprehensive view of its global transcriptomic regulation in this study.	WT 2	replicate:biological replicate 2\|strain:AB\|age:7 days\|sex:not applicable\|tissue:total\|BioSampleModel:Model organism or animal	Diano rerio transcriptome	WT 2 20190506 2	WT 2 20190506 2	RNA seq of WT Diano rerio	RNA-Seq	TRANSCRIPTOMIC	other	SINGLE	BGISEQ	BGISEQ-500	SRP195685	loader:fastq load.py	WT2.1.fq	fastq	1095133200.0	21902664.0	WT2.1.fq	0:50	A:290594757;C:255644044;G:259681140;T:288014102;N:1199157	50		290594757	255644044	259681140	288014102	1199157	SRX5799153	SRS4730323	SRA883435	Xiamen University\|School of Pharmaceutical Sciences	Xiamen University	1	0.93368	0.09166	0.67085	0.46523	50	B	usable mapping rate	bgi	bgi	unknown	random_priming	unknown	bulk	unknown	unknown	China	2020-01-18	Larval	Larval	Undetermined	Undetermined
52212	52212	SRR9021060	SRX5799152	SRS4730322	SRP195685	PRJNA541367	Global transcriptomic analysis of zebrafish glucagon receptor mutant	PRJNA541367	Other	We performed RNA sequencing RNA seq analysis of whole fish to provide a comprehensive view of its global transcriptomic regulation in this study.	WT 3	replicate:biological replicate 3\|strain:AB\|age:7 days\|sex:not applicable\|tissue:total\|BioSampleModel:Model organism or animal	Diano rerio transcriptome	WT 3 20190506 3	WT 3 20190506 3	RNA seq of WT Diano rerio	RNA-Seq	TRANSCRIPTOMIC	other	SINGLE	BGISEQ	BGISEQ-500	SRP195685	loader:fastq load.py	WT3.1.fq	fastq	1096083900.0	21921678.0	WT3.1.fq	0:50	A:290332094;C:256993500;G:263043956;T:285349722;N:364628	50		290332094	256993500	263043956	285349722	364628	SRX5799152	SRS4730322	SRA883435	Xiamen University\|School of Pharmaceutical Sciences	Xiamen University	1	0.94147	0.10157	0.66135	0.47301	50	B	usable mapping rate	bgi	bgi	unknown	random_priming	unknown	bulk	unknown	unknown	China	2020-01-18	Larval	Larval	Undetermined	Undetermined
52213	52213	SRR9021061	SRX5799151	SRS4730320	SRP195685	PRJNA541367	Global transcriptomic analysis of zebrafish glucagon receptor mutant	PRJNA541367	Other	We performed RNA sequencing RNA seq analysis of whole fish to provide a comprehensive view of its global transcriptomic regulation in this study.	gcgr 1	replicate:biological replicate 1\|strain:AB\|age:7 days\|sex:not applicable\|tissue:total\|BioSampleModel:Model organism or animal	Diano rerio transcriptome	gcgr 1 20190506 1	gcgr 1 20190506 1	RNA seq of Diano rerio with gcgr mutant	RNA-Seq	TRANSCRIPTOMIC	other	SINGLE	BGISEQ	BGISEQ-500	SRP195685	loader:fastq load.py	gcgr1.1.fq	fastq	1096307200.0	21926144.0	gcgr1.1.fq	0:50	A:288839446;C:258297625;G:264630675;T:284199738;N:339716	50		288839446	258297625	264630675	284199738	339716	SRX5799151	SRS4730320	SRA883435	Xiamen University\|School of Pharmaceutical Sciences	Xiamen University	1	0.94131	0.09307	0.67574	0.46993	50	B	usable mapping rate	bgi	bgi	unknown	random_priming	unknown	bulk	unknown	unknown	China	2020-01-18	Larval	Larval	Undetermined	Undetermined
52214	52214	SRR9021062	SRX5799150	SRS4730321	SRP195685	PRJNA541367	Global transcriptomic analysis of zebrafish glucagon receptor mutant	PRJNA541367	Other	We performed RNA sequencing RNA seq analysis of whole fish to provide a comprehensive view of its global transcriptomic regulation in this study.	gcgr 2	replicate:biological replicate 2\|strain:AB\|age:7 days\|sex:not applicable\|tissue:total\|BioSampleModel:Model organism or animal	Diano rerio transcriptome	gcgr 2 20190506 2	gcgr 2 20190506 2	RNA seq of Diano rerio with gcgr mutant	RNA-Seq	TRANSCRIPTOMIC	other	SINGLE	BGISEQ	BGISEQ-500	SRP195685	loader:fastq load.py	gcgr2.1.fq	fastq	1094410100.0	21888202.0	gcgr2.1.fq	0:50	A:290062779;C:256358687;G:264488431;T:282812212;N:687991	50		290062779	256358687	264488431	282812212	687991	SRX5799150	SRS4730321	SRA883435	Xiamen University\|School of Pharmaceutical Sciences	Xiamen University	1	0.94074	0.09337	0.67633	0.46861	50	B	usable mapping rate	bgi	bgi	unknown	random_priming	unknown	bulk	unknown	unknown	China	2020-01-18	Larval	Larval	Undetermined	Undetermined
52215	52215	SRR9021063	SRX5799149	SRS4730319	SRP195685	PRJNA541367	Global transcriptomic analysis of zebrafish glucagon receptor mutant	PRJNA541367	Other	We performed RNA sequencing RNA seq analysis of whole fish to provide a comprehensive view of its global transcriptomic regulation in this study.	gcgr 3	replicate:biological replicate 3\|strain:AB\|age:7 days\|sex:not applicable\|tissue:total\|BioSampleModel:Model organism or animal	Diano rerio transcriptome	gcgr 3 20190506 3	gcgr 3 20190506 3	RNA seq of Diano rerio with gcgr mutant	RNA-Seq	TRANSCRIPTOMIC	other	SINGLE	BGISEQ	BGISEQ-500	SRP195685	loader:fastq load.py	gcgr3.1.fq	fastq	1094284800.0	21885696.0	gcgr3.1.fq	0:50	A:289313514;C:257096636;G:264011408;T:283143600;N:719642	50		289313514	257096636	264011408	283143600	719642	SRX5799149	SRS4730319	SRA883435	Xiamen University\|School of Pharmaceutical Sciences	Xiamen University	1	0.94222	0.09557	0.67521	0.46664	50	B	usable mapping rate	bgi	bgi	unknown	random_priming	unknown	bulk	unknown	unknown	China	2020-01-18	Larval	Larval	Undetermined	Undetermined
66964	66964	SRR16965143	SRX13156592	SRS11088496	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:10 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :mixture group	mix 1	mix 1	96hpf zebrafish larvae mixture group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		mix2_1_2.fq.gz	fastq	3313823250.0	22092155.0	mix2 1 2.fq.gz	0:0 1:150	A:895726357;C:763402657;G:745765587;T:908922686;N:5963	0	150	895726357	763402657	745765587	908922686	5963	SRX13156592	SRS11088496	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.93604	0.10794	0.65587	0.47956	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66965	66965	SRR16965144	SRX13156591	SRS11088495	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3enf	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:9 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :enrofloxacin group	enf 3	enf 3	96hpf zebrafish larvae enrofloxacin group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		enf_3.fq.gz	fastq	3304972350.0	22033149.0	enf 3.fq.gz	0:150 1:0	A:899427202;C:745999066;G:759917309;T:899625137;N:3636	150	0	899427202	745999066	759917309	899625137	3636	SRX13156591	SRS11088495	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94353	0.10795	0.66212	0.47773	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66967	66967	SRR16965146	SRX13156589	SRS11088492	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3car	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:6 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :carbendazim group	car 3	car 3	96hpf zebrafish larvae carbendazim group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		car_3_1.fq.gz	fastq	3335622150.0	22237481.0	car 3 1.fq.gz	0:150 1:0	A:853229671;C:807433601;G:820478265;T:854475092;N:5521	150	0	853229671	807433601	820478265	854475092	5521	SRX13156589	SRS11088492	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.96567	0.03093	0.70997	0.47751	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66968	66968	SRR16965147	SRX13156588	SRS11088494	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1car	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:4 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :carbendazim group	car 1	car 1	96hpf zebrafish larvae carbendazim group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		car_1_1.fq.gz	fastq	3378056400.0	22520376.0	car 1 1.fq.gz	0:150 1:0	A:886009175;C:795203398;G:809447342;T:887390300;N:6185	150	0	886009175	795203398	809447342	887390300	6185	SRX13156588	SRS11088494	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95701	0.05956	0.67836	0.4884	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66969	66969	SRR16965148	SRX13156587	SRS11088491	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:3 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :control group	con 3	con 3	96hpf zebrafish larvae control group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		con_3_2.fq.gz	fastq	3359054500.0	33590545.0	con 3 2.fq.gz	0:100 1:0	A:914533337;C:755914202;G:773676246;T:914930715;N:0	100	0	914533337	755914202	773676246	914930715	0	SRX13156587	SRS11088491	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95076	0.10478	0.65646	0.49594	100	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66970	66970	SRR16965149	SRX13156586	SRS11088489	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	3mix	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:12 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :mixture group	mix 3	mix 3	96hpf zebrafish larvae mixture group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547		mix2_3_1.fq.gz	fastq	3362094000.0	33620940.0	mix2 3 1.fq.gz	0:100 1:0	A:916124379;C:755910593;G:768246534;T:921812494;N:0	100	0	916124379	755910593	768246534	921812494	0	SRX13156586	SRS11088489	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94894	0.10416	0.65342	0.49475	100	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-17	Larval	Larval	Undetermined	Undetermined
66972	66972	SRR16965151	SRX13156584	SRS11088488	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	2con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:2 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :control group	con 2	con 2	96hpf zebrafish larvae control group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547	loader:fastq load.py	con_2_2.fq	fastq	3324287550.0	22161917.0	con 2 2.fq.gz	0:150	A:848766265;C:812477645;G:798995610;T:864040426;N:7604	150		848766265	812477645	798995610	864040426	7604	SRX13156584	SRS11088488	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95546	0.03524	0.70027	0.48649	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-22	Larval	Larval	Undetermined	Undetermined
66973	66973	SRR16965152	SRX13156583	SRS11088487	SRP346547	PRJNA780808	transcriptomics of carbendazim and enrofloxacin on zebrafish embryos	PRJNA780808	Other	reveal a interaction between ENF and CAR on metabolic regulation during development	1con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:1 96hpf\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio :control group	con 1	con 1	96hpf zebrafish larvae control group	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346547	loader:fastq load.py	con_1_1.fq	fastq	3330724500.0	22204830.0	con 1 1.fq.gz	0:150	A:896812508;C:762246067;G:774062043;T:897597946;N:5936	150		896812508	762246067	774062043	897597946	5936	SRX13156583	SRS11088487	SRA1329868	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94926	0.08711	0.66789	0.48628	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-22	Larval	Larval	Undetermined	Undetermined
66975	66975	SRR16959539	SRX13151073	SRS11083379	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2dim	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:8 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : dimethomorph group	dim 2	dim 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dim_2_1.fq.gz	fastq	3344257500.0	22295050.0	dim 2 1.fq.gz	0:150 1:0	A:895700119;C:767415749;G:784994320;T:896143585;N:3727	150	0	895700119	767415749	784994320	896143585	3727	SRX13151073	SRS11083379	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.9497	0.08418	0.66352	0.49341	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66976	66976	SRR16959540	SRX13151072	SRS11083378	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1dim	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:7 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : dimethomorph group	dim 1	dim 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dim_1_1.fq.gz	fastq	3318812250.0	22125415.0	dim 1 1.fq.gz	0:150 1:0	A:908481293;C:742787936;G:755930542;T:911608821;N:3658	150	0	908481293	742787936	755930542	911608821	3658	SRX13151072	SRS11083378	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94211	0.11824	0.65344	0.47716	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66977	66977	SRR16959541	SRX13151071	SRS11083377	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	3dif	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:6 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : difenoconazole group	dif 3	dif 3	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dif_3_1.fq.gz	fastq	3318453000.0	22123020.0	dif 3 1.fq.gz	0:150 1:0	A:893975607;C:758489621;G:772391705;T:893592335;N:3732	150	0	893975607	758489621	772391705	893592335	3732	SRX13151071	SRS11083377	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94838	0.08393	0.66543	0.4818	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66978	66978	SRR16959542	SRX13151070	SRS11083376	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2dif	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:5 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : difenoconazole group	dif 2	dif 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dif_2_2.fq.gz	fastq	3304972350.0	22033149.0	dif 2 2.fq.gz	0:0 1:150	A:890456734;C:764917766;G:744757536;T:904833787;N:6527	0	150	890456734	764917766	744757536	904833787	6527	SRX13151070	SRS11083376	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.93514	0.107	0.6633	0.47599	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66979	66979	SRR16959543	SRX13151069	SRS11083375	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1dif	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:4 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : difenoconazole group	dif 1	dif 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		dif_1_1.fq.gz	fastq	3295443900.0	21969626.0	dif 1 1.fq.gz	0:150 1:0	A:887936493;C:751636494;G:765508757;T:890358629;N:3527	150	0	887936493	751636494	765508757	890358629	3527	SRX13151069	SRS11083375	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94623	0.09138	0.66478	0.4828	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66980	66980	SRR16959544	SRX13151068	SRS11083374	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	3+con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:3 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : control group	con 3	con 3	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		con_3_1.fq.gz	fastq	3306406800.0	22042712.0	con 3 1.fq.gz	0:150 1:0	A:872740236;C:773482184;G:788334419;T:871846539;N:3422	150	0	872740236	773482184	788334419	871846539	3422	SRX13151068	SRS11083374	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95458	0.06103	0.67409	0.48439	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66982	66982	SRR16959546	SRX13151066	SRS11083372	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	2+con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:2 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : control group	con 2	con 2	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		con_2_2.fq.gz	fastq	3324287550.0	22161917.0	con 2 2.fq.gz	0:0 1:150	A:848766265;C:812477645;G:798995610;T:864040426;N:7604	0	150	848766265	812477645	798995610	864040426	7604	SRX13151066	SRS11083372	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.95548	0.03524	0.70021	0.4867	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
66983	66983	SRR16959547	SRX13151065	SRS11083371	SRP346418	PRJNA780940	transcriptomics of difenoconazole and dimethomorph on zebrafish embryos	PRJNA780940	Other	Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples so the deleterious effects of combined exposure warrant detailed examination. In this study the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate deformity rate lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes cdk1 and cdc20 thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.	1+con	strain:Tu\|isolate:N/A\|breed:N/A\|cultivar:N/A\|ecotype:N/A\|age:1 96h\|dev stage:larvae\|sex:male and female\|tissue:larvae\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio : control group	con 1	con 1	The final library was amplified with phi29 to make DNA nanoballs DNB with more than 300 copies of one molecular.	RNA-Seq	TRANSCRIPTOMIC	Oligo-dT	SINGLE	BGISEQ	BGISEQ-500	SRP346418		con_1_1.fq.gz	fastq	3330724500.0	22204830.0	con 1 1.fq.gz	0:150 1:0	A:896812508;C:762246067;G:774062043;T:897597946;N:5936	150	0	896812508	762246067	774062043	897597946	5936	SRX13151065	SRS11083371	SRA1330365	China Agricultural University\|College of animal science and technology	China Agricultural University	1	0.94925	0.08711	0.66772	0.48635	150	B	usable mapping rate	bgi	bgi	unknown	poly_a	unknown	bulk	unknown	unknown	China	2021-11-16	Larval	Larval	Undetermined	Undetermined
68473	68473	SRR17793192	SRX13955361	SRS11795776	SRP357103	PRJNA801348	Global studies of Nur77 on metabolism of zebrafish	PRJNA801348	Other	We created a global Nur77 knockout zebrafish model by CRISPR/Cas9 technique and then performed the whole organism RNA sequencing analysis in wild type and nur77 deficient zebrafish to dissect the changes genes in metabolic related pathways.	WT3	strain:WT replicate 3\|age:6 dpf\|sex:male and female\|tissue:Total\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: 6 dpf larvea	Li lab Nur77 6	Li lab Nur77 6	There are two groups: WT and Nur77 mutant. Every group has three replicates.	RNA-Seq	TRANSCRIPTOMIC	cDNA	SINGLE	BGISEQ	BGISEQ-500	SRP357103		WT3.fq.gz	fastq	1076798350.0	21535967.0	WT3.fq.gz	0:50 1:0	A:290308649;C:238961327;G:249860004;T:297257553;N:410817	50	0	290308649	238961327	249860004	297257553	410817	SRX13955361	SRS11795776	SRA1363249	Xiamen University\|School of pharmaceutical sciences	Xiamen University	1	0.9388	0.12749	0.66087	0.4989	50	B	usable mapping rate	bgi	bgi	unknown	cdna_unspecified	unknown	bulk	unknown	unknown	China	2022-01-27	Larval	Larval	Undetermined	Undetermined
68474	68474	SRR17793193	SRX13955360	SRS11795775	SRP357103	PRJNA801348	Global studies of Nur77 on metabolism of zebrafish	PRJNA801348	Other	We created a global Nur77 knockout zebrafish model by CRISPR/Cas9 technique and then performed the whole organism RNA sequencing analysis in wild type and nur77 deficient zebrafish to dissect the changes genes in metabolic related pathways.	WT2	strain:WT replicate 2\|age:6 dpf\|sex:male and female\|tissue:Total\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: 6 dpf larvea	Li lab Nur77 5	Li lab Nur77 5	There are two groups: WT and Nur77 mutant. Every group has three replicates.	RNA-Seq	TRANSCRIPTOMIC	cDNA	SINGLE	BGISEQ	BGISEQ-500	SRP357103		WT2.fq.gz	fastq	1076181450.0	21523629.0	WT2.fq.gz	0:50 1:0	A:289932885;C:238687076;G:249724577;T:297412345;N:424567	50	0	289932885	238687076	249724577	297412345	424567	SRX13955360	SRS11795775	SRA1363249	Xiamen University\|School of pharmaceutical sciences	Xiamen University	1	0.93932	0.1297	0.66038	0.48203	50	B	usable mapping rate	bgi	bgi	unknown	cdna_unspecified	unknown	bulk	unknown	unknown	China	2022-01-27	Larval	Larval	Undetermined	Undetermined
68475	68475	SRR17793194	SRX13955359	SRS11795774	SRP357103	PRJNA801348	Global studies of Nur77 on metabolism of zebrafish	PRJNA801348	Other	We created a global Nur77 knockout zebrafish model by CRISPR/Cas9 technique and then performed the whole organism RNA sequencing analysis in wild type and nur77 deficient zebrafish to dissect the changes genes in metabolic related pathways.	WT1	strain:WT replicate 1\|age:6 dpf\|sex:male and female\|tissue:Total\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: 6 dpf larvea	Li lab Nur77 4	Li lab Nur77 4	There are two groups: WT and Nur77 mutant. Every group has three replicates.	RNA-Seq	TRANSCRIPTOMIC	cDNA	SINGLE	BGISEQ	BGISEQ-500	SRP357103		WT1.fq.gz	fastq	1076191400.0	21523828.0	WT1.fq.gz	0:50 1:0	A:291276889;C:238480546;G:249179972;T:296814696;N:439297	50	0	291276889	238480546	249179972	296814696	439297	SRX13955359	SRS11795774	SRA1363249	Xiamen University\|School of pharmaceutical sciences	Xiamen University	1	0.93825	0.12843	0.66119	0.49668	50	B	usable mapping rate	bgi	bgi	unknown	cdna_unspecified	unknown	bulk	unknown	unknown	China	2022-01-27	Larval	Larval	Undetermined	Undetermined
68476	68476	SRR17793195	SRX13955358	SRS11795773	SRP357103	PRJNA801348	Global studies of Nur77 on metabolism of zebrafish	PRJNA801348	Other	We created a global Nur77 knockout zebrafish model by CRISPR/Cas9 technique and then performed the whole organism RNA sequencing analysis in wild type and nur77 deficient zebrafish to dissect the changes genes in metabolic related pathways.	nur77KO3	strain:nur77KO replicate 3\|age:6 dpf\|sex:male and female\|tissue:Total\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: 6 dpf larvea	Li lab Nur77 3	Li lab Nur77 3	There are two groups: WT and Nur77 mutant. Every group has three replicates.	RNA-Seq	TRANSCRIPTOMIC	cDNA	SINGLE	BGISEQ	BGISEQ-500	SRP357103		Nur773.fq.gz	fastq	1076004450.0	21520089.0	Nur773.fq.gz	0:50 1:0	A:290229363;C:238956151;G:246664664;T:299742511;N:411761	50	0	290229363	238956151	246664664	299742511	411761	SRX13955358	SRS11795773	SRA1363249	Xiamen University\|School of pharmaceutical sciences	Xiamen University	1	0.93696	0.13828	0.66397	0.48777	50	B	usable mapping rate	bgi	bgi	unknown	cdna_unspecified	unknown	bulk	unknown	unknown	China	2022-01-27	Larval	Larval	Undetermined	Undetermined
68477	68477	SRR17793196	SRX13955357	SRS11795772	SRP357103	PRJNA801348	Global studies of Nur77 on metabolism of zebrafish	PRJNA801348	Other	We created a global Nur77 knockout zebrafish model by CRISPR/Cas9 technique and then performed the whole organism RNA sequencing analysis in wild type and nur77 deficient zebrafish to dissect the changes genes in metabolic related pathways.	nur77KO2	strain:nur77KO replicate 2\|age:6 dpf\|sex:male and female\|tissue:Total\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: 6 dpf larvea	Li lab Nur77 2	Li lab Nur77 2	There are two groups: WT and Nur77 mutant. Every group has three replicates.	RNA-Seq	TRANSCRIPTOMIC	cDNA	SINGLE	BGISEQ	BGISEQ-500	SRP357103		Nur772.fq.gz	fastq	1075868050.0	21517361.0	Nur772.fq.gz	0:50 1:0	A:288260097;C:241294246;G:250714084;T:295165628;N:433995	50	0	288260097	241294246	250714084	295165628	433995	SRX13955357	SRS11795772	SRA1363249	Xiamen University\|School of pharmaceutical sciences	Xiamen University	1	0.94112	0.11813	0.66582	0.48643	50	B	usable mapping rate	bgi	bgi	unknown	cdna_unspecified	unknown	bulk	unknown	unknown	China	2022-01-27	Larval	Larval	Undetermined	Undetermined
68478	68478	SRR17793197	SRX13955356	SRS11795771	SRP357103	PRJNA801348	Global studies of Nur77 on metabolism of zebrafish	PRJNA801348	Other	We created a global Nur77 knockout zebrafish model by CRISPR/Cas9 technique and then performed the whole organism RNA sequencing analysis in wild type and nur77 deficient zebrafish to dissect the changes genes in metabolic related pathways.	nur77KO1	strain:nur77KO replicate 1\|age:6 dpf\|sex:male and female\|tissue:Total\|BioSampleModel:Model organism or animal	RNA Seq of Danio rerio: 6 dpf larvea	Li lab Nur77 1	Li lab Nur77 1	There are two groups: WT and Nur77 mutant. Every group has three replicates.	RNA-Seq	TRANSCRIPTOMIC	cDNA	SINGLE	BGISEQ	BGISEQ-500	SRP357103		Nur771.fq.gz	fastq	1075810450.0	21516209.0	Nur771.fq.gz	0:50 1:0	A:287851992;C:241486200;G:251500529;T:294560911;N:410818	50	0	287851992	241486200	251500529	294560911	410818	SRX13955356	SRS11795771	SRA1363249	Xiamen University\|School of pharmaceutical sciences	Xiamen University	1	0.94193	0.11554	0.6676	0.49728	50	B	usable mapping rate	bgi	bgi	unknown	cdna_unspecified	unknown	bulk	unknown	unknown	China	2022-01-27	Larval	Larval	Undetermined	Undetermined

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CREATE TABLE run_metadata("run.accession" VARCHAR, "experiment.accession" VARCHAR, "sample.accession" VARCHAR, "study.accession" VARCHAR, bioproject VARCHAR, "study.title" VARCHAR, "study.alias" VARCHAR, "study.type" VARCHAR, "study.abstract" VARCHAR, "study.attributes" VARCHAR, "study.PMIDs" VARCHAR, "sample.description" VARCHAR, "sample.title" VARCHAR, "sample.alias" VARCHAR, "sample.centername" VARCHAR, "sample.attributes" VARCHAR, "GEOsample.title" VARCHAR, "GEOsample.dataprocessing" VARCHAR, "GEOsample.source" VARCHAR, "GEOsample.treatmentprotocol" VARCHAR, "GEOsample.extractprotocol" VARCHAR, "GEOsample.growthprotocol" VARCHAR, "GEOsample.characteristics" VARCHAR, "GEOsample.accession" VARCHAR, "experiment.title" VARCHAR, "experiment.alias" VARCHAR, "experiment.library_name" VARCHAR, "experiment.design_description" VARCHAR, "experiment.library_construction_protocol" VARCHAR, "experiment.attributes" VARCHAR, "experiment.library_strategy" VARCHAR, "experiment.library_source" VARCHAR, "experiment.library_selection" VARCHAR, "experiment.library_layout" VARCHAR, "experiment.platform" VARCHAR, "experiment.instrument_model" VARCHAR, "experiment.spot_descriptor" VARCHAR, "experiment.study_ref" VARCHAR, "run.title" VARCHAR, "run.attributes" VARCHAR, "run.filename" VARCHAR, "run.semantic_name" VARCHAR, "run.total_bases" DOUBLE, "run.total_spots" DOUBLE, "run.alias" VARCHAR, "run.read_lengths" VARCHAR, "run.base_counts" VARCHAR, "run.r1_length" BIGINT, "run.r2_length" BIGINT, "run.r3_length" BIGINT, "run.r4_length" BIGINT, "run.Acount" BIGINT, "run.Ccount" BIGINT, "run.Gcount" BIGINT, "run.Tcount" BIGINT, "run.Ncount" BIGINT, "run.experiment" VARCHAR, "run.pool_member" VARCHAR, "submission.accession" VARCHAR, "submission.srasource" VARCHAR, "submission.bioprojectsource" VARCHAR, "seqdetective.n_mates" BIGINT, "seqdetective.mapping_rate.mate1" DOUBLE, "seqdetective.mapping_rate.mate2" DOUBLE, "seqdetective.nofeature_rate.mate1" DOUBLE, "seqdetective.nofeature_rate.mate2" DOUBLE, "seqdetective.sparsity.mate1" DOUBLE, "seqdetective.sparsity.mate2" DOUBLE, "seqdetective.pos_strand_rate.mate1" DOUBLE, "seqdetective.pos_strand_rate.mate2" DOUBLE, "seqdetective.readlen.mate1" BIGINT, "seqdetective.readlen.mate2" BIGINT, "seqdetective.judgement.mate1" VARCHAR, "seqdetective.judgement.mate2" VARCHAR, "seqdetective.judgement.reason" VARCHAR, platform_family VARCHAR, instrument_generation VARCHAR, read_bias VARCHAR, selection_class VARCHAR, prep_kit VARCHAR, sc_or_bulk VARCHAR, tech_class VARCHAR, technology VARCHAR, tech_variant VARCHAR, "submission.bioprojectsource.country" VARCHAR, earliest_date DATE, devstage_curation VARCHAR, devstage_curation_coarse VARCHAR, tissue_curation VARCHAR, tissue_curation_coarse VARCHAR);;
CREATE INDEX idx_run_bioproject ON run_metadata(bioproject);;
CREATE INDEX idx_run_run_accession ON run_metadata("run.accession");;