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Total RNA was extracted using TRIzol Plus RNA Purification Kit. cDNA libraries were generated by Oligo dT for sequencing.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP346689", null, "loader:fastq load.py|options:  doNotUseSharq   allowEarlyFileEnd    maxErrorCount=0", "Daniorerio_3months_MU2-T02_good_1.fq.gz Daniorerio_3months_MU2-T02_good_2.fq.gz", "fastq fastq", 7319481642.0, 24455109.0, "Daniorerio 3months MU2 T02 good 1.fq.gz", "0:149.65 1:149.65", "A:1950119505;C:1698268609;G:1716794920;T:1954208020;N:90588", 149, 149, null, null, 1950119505, 1698268609, 1716794920, 1954208020, 90588, "SRX13163292", "SRS11094635", "SRA1330971", "Sun Yat-sen University|School of Life Sciences", "Sun Yat-sen University", 2, 0.91605, 0.91629, 0.07171, 0.0721, 0.73099, 0.73277, 0.51829, 0.51094, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-19", "Adult", "Adult", "Gut", "Digestive System"], [67015, "SRR16972435", "SRX13163291", "SRS11094635", "SRP346689", "PRJNA781427", "RNA Seq analysis of wild type and chs1 /  zebrafish gut", "PRJNA781427", "Other", "To investigate the mRNA expression profiles in the intestine of wild type and chitin synthase 1 knock out chs1 /  zebrafish  extracted total RNA of intestine from samples of different ages to generate cDNA libraries  and sequenced using Illumina NovaSeq 6000 system platform.", null, null, null, null, "MU 3M", null, "breed:TU|age:3 mpf|dev stage:Adult|sex:not collected|tissue:Intestine|birth date:2020 07 08|collection date:2020 10 15|death date:2020 10 15|genotype:chs1 / |health state:health|sample type:tissue sample|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult gut", "MU 3M rep1", "MU 3M rep1", "Adults Danio rerio were euthanized by MS 222  whole intestines were collected from the abdomen region. Total RNA was extracted using TRIzol Plus RNA Purification Kit. cDNA libraries were generated by Oligo dT for sequencing.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP346689", null, "loader:fastq load.py|options:  doNotUseSharq   allowEarlyFileEnd    maxErrorCount=0", "Daniorerio_3months_MU1-T01_good_1.fq.gz Daniorerio_3months_MU1-T01_good_2.fq.gz", "fastq fastq", 6689783730.0, 22374730.0, "Daniorerio 3months MU1 T01 good 1.fq.gz", "0:149.49 1:149.49", "A:1791825331;C:1543674432;G:1559586766;T:1794614998;N:82203", 149, 149, null, null, 1791825331, 1543674432, 1559586766, 1794614998, 82203, "SRX13163291", "SRS11094635", "SRA1330971", "Sun Yat-sen University|School of Life Sciences", "Sun Yat-sen University", 2, 0.89988, 0.90023, 0.07447, 0.07414, 0.73318, 0.7347, 0.52608, 0.52855, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-19", "Adult", "Adult", "Gut", "Digestive System"], [67016, "SRR16972436", "SRX13163290", "SRS11094634", "SRP346689", "PRJNA781427", "RNA Seq analysis of wild type and chs1 /  zebrafish gut", "PRJNA781427", "Other", "To investigate the mRNA expression profiles in the intestine of wild type and chitin synthase 1 knock out chs1 /  zebrafish  extracted total RNA of intestine from samples of different ages to generate cDNA libraries  and sequenced using Illumina NovaSeq 6000 system platform.", null, null, null, null, "SMU 6M", null, "breed:TU|age:6 mpf|dev stage:Adult|sex:not collected|tissue:Intestine|birth date:2020 07 08|collection date:2020 12 29|death date:2020 12 29|genotype:chs1 / |health state:sick|sample type:tissue sample|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult gut", "SMU 6M rep2", "SMU 6M rep2", "Adults Danio rerio were euthanized by MS 222  whole intestines were collected from the abdomen region. Total RNA was extracted using TRIzol Plus RNA Purification Kit. cDNA libraries were generated by Oligo dT for sequencing.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP346689", null, "loader:fastq load.py|options:  doNotUseSharq   allowEarlyFileEnd    maxErrorCount=0", "Daniorerio_6months_SMU2-T09_good_1.fq.gz Daniorerio_6months_SMU2-T09_good_2.fq.gz", "fastq fastq", 6153057638.0, 20567236.0, "Daniorerio 6months SMU2 T09 good 1.fq.gz", "0:149.58 1:149.58", "A:1623915064;C:1438971834;G:1466951426;T:1623205362;N:13952", 149, 149, null, null, 1623915064, 1438971834, 1466951426, 1623205362, 13952, "SRX13163290", "SRS11094634", "SRA1330971", "Sun Yat-sen University|School of Life Sciences", "Sun Yat-sen University", 2, 0.89898, 0.89771, 0.08023, 0.07995, 0.715, 0.71648, 0.49782, 0.48134, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-19", "Adult", "Adult", "Gut", "Digestive System"], [67017, "SRR16972437", "SRX13163289", "SRS11094634", "SRP346689", "PRJNA781427", "RNA Seq analysis of wild type and chs1 /  zebrafish gut", "PRJNA781427", "Other", "To investigate the mRNA expression profiles in the intestine of wild type and chitin synthase 1 knock out chs1 /  zebrafish  extracted total RNA of intestine from samples of different ages to generate cDNA libraries  and sequenced using Illumina NovaSeq 6000 system platform.", null, null, null, null, "SMU 6M", null, "breed:TU|age:6 mpf|dev stage:Adult|sex:not collected|tissue:Intestine|birth date:2020 07 08|collection date:2020 12 29|death date:2020 12 29|genotype:chs1 / |health state:sick|sample type:tissue sample|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult gut", "SMU 6M rep1", "SMU 6M rep1", "Adults Danio rerio were euthanized by MS 222  whole intestines were collected from the abdomen region. Total RNA was extracted using TRIzol Plus RNA Purification Kit. cDNA libraries were generated by Oligo dT for sequencing.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP346689", null, "loader:fastq load.py|options:  doNotUseSharq   allowEarlyFileEnd    maxErrorCount=0", "Daniorerio_6months_SMU1-T08_good_1.fq.gz Daniorerio_6months_SMU1-T08_good_2.fq.gz", "fastq fastq", 6402267634.0, 21457841.0, "Daniorerio 6months SMU1 T08 good 1.fq.gz", "0:149.18 1:149.18", "A:1705727400;C:1483728129;G:1516588316;T:1696209255;N:14534", 149, 149, null, null, 1705727400, 1483728129, 1516588316, 1696209255, 14534, "SRX13163289", "SRS11094634", "SRA1330971", "Sun Yat-sen University|School of Life Sciences", "Sun Yat-sen University", 2, 0.92502, 0.92362, 0.09504, 0.09399, 0.69323, 0.69568, 0.4847, 0.48708, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-19", "Adult", "Adult", "Gut", "Digestive System"], [74161, "SRR23576625", "SRX19463432", "SRS16856055", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M9", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M9", "M9", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M9_1.fq.gz M9_2.fq.gz", "fastq fastq", 10791781600.0, 107917816.0, "M9 1.fq.gz", "0:100 1:100", "A:2848108353;C:2487301410;G:2561260439;T:2895111398;N:0", 100, 100, null, null, 2848108353, 2487301410, 2561260439, 2895111398, 0, "SRX19463432", "SRS16856055", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95252, null, 0.05974, null, 0.79184, null, 0.6274, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74162, "SRR23576626", "SRX19463431", "SRS16856054", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M8", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M8", "M8", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M8_1.fq.gz M8_2.fq.gz", "fastq fastq", 10803624400.0, 108036244.0, "M8 1.fq.gz", "0:100 1:100", "A:2826927335;C:2516499907;G:2585204327;T:2874992831;N:0", 100, 100, null, null, 2826927335, 2516499907, 2585204327, 2874992831, 0, "SRX19463431", "SRS16856054", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95494, null, 0.06268, null, 0.79139, null, 0.60873, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74163, "SRR23576627", "SRX19463430", "SRS16856053", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M7", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M7", "M7", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M7_1.fq.gz M7_2.fq.gz", "fastq fastq", 10794944600.0, 107949446.0, "M7 1.fq.gz", "0:100 1:100", "A:2822800001;C:2515936087;G:2583221720;T:2872986792;N:0", 100, 100, null, null, 2822800001, 2515936087, 2583221720, 2872986792, 0, "SRX19463430", "SRS16856053", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95392, null, 0.0552, null, 0.78967, null, 0.61766, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74164, "SRR23576628", "SRX19463429", "SRS16856052", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M6", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M6", "M6", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M6_1.fq.gz M6_2.fq.gz", "fastq fastq", 10806717200.0, 108067172.0, "M6 1.fq.gz", "0:100 1:100", "A:2872422644;C:2476696362;G:2537205428;T:2920392766;N:0", 100, 100, null, null, 2872422644, 2476696362, 2537205428, 2920392766, 0, "SRX19463429", "SRS16856052", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95383, null, 0.06563, null, 0.79293, null, 0.63948, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74165, "SRR23576629", "SRX19463428", "SRS16856051", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M5", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M5", "M5", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M5_1.fq.gz M5_2.fq.gz", "fastq fastq", 10553024000.0, 105530240.0, "M5 1.fq.gz", "0:100 1:100", "A:2756587901;C:2467885042;G:2531072385;T:2797478672;N:0", 100, 100, null, null, 2756587901, 2467885042, 2531072385, 2797478672, 0, "SRX19463428", "SRS16856051", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95761, null, 0.05754, null, 0.79435, null, 0.61791, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74166, "SRR23576630", "SRX19463427", "SRS16856048", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M4", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M4", "M4", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M4_1.fq.gz M4_2.fq.gz", "fastq fastq", 10821109400.0, 108211094.0, "M4 1.fq.gz", "0:100 1:100", "A:2853720356;C:2500021520;G:2567460910;T:2899906614;N:0", 100, 100, null, null, 2853720356, 2500021520, 2567460910, 2899906614, 0, "SRX19463427", "SRS16856048", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95171, null, 0.0636, null, 0.78644, null, 0.61061, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74174, "SRR23576638", "SRX19463419", "SRS16856040", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M3", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M3", "M3", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M3_1.fq.gz M3_2.fq.gz", "fastq fastq", 10811204400.0, 108112044.0, "M3 1.fq.gz", "0:100 1:100", "A:2826338851;C:2514522241;G:2594843889;T:2875499419;N:0", 100, 100, null, null, 2826338851, 2514522241, 2594843889, 2875499419, 0, "SRX19463419", "SRS16856040", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95049, null, 0.05611, null, 0.79127, null, 0.60997, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74185, "SRR23576649", "SRX19463408", "SRS16856031", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M2", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M2", "M2", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M2_1.fq.gz M2_2.fq.gz", "fastq fastq", 10784874600.0, 107848746.0, "M2 1.fq.gz", "0:100 1:100", "A:2800268243;C:2532669517;G:2601088355;T:2850848485;N:0", 100, 100, null, null, 2800268243, 2532669517, 2601088355, 2850848485, 0, "SRX19463408", "SRS16856031", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95513, null, 0.05808, null, 0.78171, null, 0.60306, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74186, "SRR23576650", "SRX19463407", "SRS16856030", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M1", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M1", "M1", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M1_1.fq.gz M1_2.fq.gz", "fastq fastq", 10797666400.0, 107976664.0, "M1 1.fq.gz", "0:100 1:100", "A:2818869037;C:2522566664;G:2592727107;T:2863503592;N:0", 100, 100, null, null, 2818869037, 2522566664, 2592727107, 2863503592, 0, "SRX19463407", "SRS16856030", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95195, null, 0.06111, null, 0.78184, null, 0.6129, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"]], "truncated": false, "filtered_table_rows_count": 31, "expanded_columns": [], "expandable_columns": [], "columns": ["rowid", "run.accession", "experiment.accession", "sample.accession", "study.accession", "bioproject", "study.title", "study.alias", "study.type", "study.abstract", "study.attributes", "study.PMIDs", "sample.description", "sample.title", "sample.alias", "sample.centername", "sample.attributes", "GEOsample.title", "GEOsample.dataprocessing", "GEOsample.source", "GEOsample.treatmentprotocol", "GEOsample.extractprotocol", "GEOsample.growthprotocol", "GEOsample.characteristics", "GEOsample.accession", "experiment.title", "experiment.alias", 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