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Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g004_1.fastq.gz", "fastq", 509713380.0, 9994380.0, "DreSceMix g004 1.fastq.gz", "0:51", "A:251366594;C:61585710;G:62159129;T:134578953;N:22994", 51, null, null, null, 251366594, 61585710, 62159129, 134578953, 22994, "SRX8663215", "SRS6944340", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.67392, null, 0.54102, null, 0.86476, null, 0.37091, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60105, "SRR12141709", "SRX8663075", "SRS6944200", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of lysate for FigS2", null, "zebrafish lysate biological replicate 3", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:lysate|fig:S2|replicate:biological replicate 3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 3", "Dre 3", "cDNA was synthesized with the lysate. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g003_1.fastq.gz", "fastq", 499717482.0, 9798382.0, "DreSceMix g003 1.fastq.gz", "0:51", "A:263221073;C:56114768;G:56547079;T:123812019;N:22543", 51, null, null, null, 263221073, 56114768, 56547079, 123812019, 22543, "SRX8663075", "SRS6944200", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.63258, null, 0.48288, null, 0.86819, null, 0.35874, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60106, "SRR12141808", "SRX8662976", "SRS6944101", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of purified RNA from lysate for Fig.S2", null, "zebrafish purifiedRNA biological replicate 6", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:purified from lysate|fig:S2|replicate:biological replicate 6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 12", "Dre 12", "cDNA was synthesized with the purified RNA. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g014_1.fastq.gz", "fastq", 421063599.0, 8256149.0, "DreSceMix g014 1.fastq.gz", "0:51", "A:207118237;C:53600213;G:54041718;T:106284709;N:18722", 51, null, null, null, 207118237, 53600213, 54041718, 106284709, 18722, "SRX8662976", "SRS6944101", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.47999, null, 0.19308, null, 0.85977, null, 0.46733, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60107, "SRR12141828", "SRX8662956", "SRS6944081", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of purified RNA from lysate for Fig.S2", null, "zebrafish purifiedRNA biological replicate 4", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:purified from lysate|fig:S2|replicate:biological replicate 4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 10", "Dre 10", "cDNA was synthesized with the purified RNA. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g012_1.fastq.gz", "fastq", 626464773.0, 12283623.0, "DreSceMix g012 1.fastq.gz", "0:51", "A:263307070;C:96744908;G:98635228;T:167749896;N:27671", 51, null, null, null, 263307070, 96744908, 98635228, 167749896, 27671, "SRX8662956", "SRS6944081", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.50608, null, 0.14369, null, 0.83422, null, 0.45691, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60108, "SRR12141839", "SRX8662945", "SRS6944070", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of purified RNA from lysate for Fig.S2", null, "zebrafish purifiedRNA biological replicate 3", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:purified from lysate|fig:S2|replicate:biological replicate 3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 9", "Dre 9", "cDNA was synthesized with the purified RNA. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g011_1.fastq.gz", "fastq", 436381296.0, 8556496.0, "DreSceMix g011 1.fastq.gz", "0:51", "A:205579619;C:58008903;G:59021026;T:113752218;N:19530", 51, null, null, null, 205579619, 58008903, 59021026, 113752218, 19530, "SRX8662945", "SRS6944070", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.46615, null, 0.18281, null, 0.84778, null, 0.44592, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60109, "SRR12141850", "SRX8662934", "SRS6944059", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of purified RNA from lysate for Fig.S2", null, "zebrafish purifiedRNA biological replicate 2", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:purified from lysate|fig:S2|replicate:biological replicate 2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 8", "Dre 8", "cDNA was synthesized with the purified RNA. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g010_1.fastq.gz", "fastq", 870727437.0, 17073087.0, "DreSceMix g010 1.fastq.gz", "0:51", "A:343772776;C:142428987;G:145570260;T:238917135;N:38279", 51, null, null, null, 343772776, 142428987, 145570260, 238917135, 38279, "SRX8662934", "SRS6944059", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.52883, null, 0.1235, null, 0.82256, null, 0.45498, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60110, "SRR12141861", "SRX8662923", "SRS6944047", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of purified RNA from lysate for Fig.S2", null, "zebrafish purifiedRNA biological replicate 1", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:purified from lysate|fig:S2|replicate:biological replicate 1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 7", "Dre 7", "cDNA was synthesized with the purified RNA. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g009_1.fastq.gz", "fastq", 1875928206.0, 36782906.0, "DreSceMix g009 1.fastq.gz", "0:51", "A:684015713;C:329272255;G:335557540;T:526999083;N:83615", 51, null, null, null, 684015713, 329272255, 335557540, 526999083, 83615, "SRX8662923", "SRS6944047", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.58553, null, 0.11315, null, 0.8029, null, 0.4678, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60111, "SRR12141872", "SRX8662912", "SRS6944037", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of lysate for FigS2", null, "zebrafish lysate biological replicate 6", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:lysate|fig:S2|replicate:biological replicate 6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 6", "Dre 6", "cDNA was synthesized with the lysate. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g006_1.fastq.gz", "fastq", 390346044.0, 7653844.0, "DreSceMix g006 1.fastq.gz", "0:51", "A:194005234;C:46666192;G:46964771;T:102692143;N:17704", 51, null, null, null, 194005234, 46666192, 46964771, 102692143, 17704, "SRX8662912", "SRS6944037", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.69496, null, 0.57077, null, 0.86864, null, 0.35451, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60112, "SRR12141959", "SRX8662825", "SRS6943950", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of lysate for FigS2", null, "zebrafish lysate biological replicate 5", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:lysate|fig:S2|replicate:biological replicate 5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 5", "Dre 5", "cDNA was synthesized with the lysate. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g005_1.fastq.gz", "fastq", 684050964.0, 13412764.0, "DreSceMix g005 1.fastq.gz", "0:51", "A:318875237;C:88359396;G:89394558;T:187391266;N:30507", 51, null, null, null, 318875237, 88359396, 89394558, 187391266, 30507, "SRX8662825", "SRS6943950", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.61659, null, 0.4142, null, 0.8393, null, 0.42049, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60113, "SRR12142001", "SRX8662783", "SRS6943908", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of purified RNA from lysate for Fig.S2", null, "zebrafish purifiedRNA biological replicate 5", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:purified from lysate|fig:S2|replicate:biological replicate 5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 11", "Dre 11", "cDNA was synthesized with the purified RNA. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g013_1.fastq.gz", "fastq", 998754318.0, 19583418.0, "DreSceMix g013 1.fastq.gz", "0:51", "A:402091762;C:156702863;G:160047354;T:279867921;N:44418", 51, null, null, null, 402091762, 156702863, 160047354, 279867921, 44418, "SRX8662783", "SRS6943908", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.52766, null, 0.13651, null, 0.81237, null, 0.45557, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60114, "SRR12142002", "SRX8662782", "SRS6943907", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of lysate for FigS2", null, "zebrafish lysate biological replicate 2", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:lysate|fig:S2|replicate:biological replicate 2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 2", "Dre 2", "cDNA was synthesized with the lysate. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g002_1.fastq.gz", "fastq", 702610578.0, 13776678.0, "DreSceMix g002 1.fastq.gz", "0:51", "A:332485038;C:89482705;G:90437771;T:190173083;N:31981", 51, null, null, null, 332485038, 89482705, 90437771, 190173083, 31981, "SRX8662782", "SRS6943907", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.63597, null, 0.45832, null, 0.85088, null, 0.40969, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [60115, "SRR12142003", "SRX8662781", "SRS6943906", "SRP269853", "PRJNA643885", "performance test of DeLTa Seq", "PRJNA643885", "Other", "This data set were used for development and performance evaluation of Direct lysate targeted RNA Seq DeLTa Seq", null, null, "RNA Seq of lysate for FigS2", null, "zebrafish lysate biological replicate 1", null, "strain:AB|age:2 days|sex:hermaphrodite|tissue:whole|sample type:lysate|fig:S2|replicate:biological replicate 1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DeLTa Seq", "Dre 1", "Dre 1", "cDNA was synthesized with the lysate. Non targeted RNA Seq were conducted according to Lasy Seq ver. 1.1 protocol18 https://sites.google.com/view/lasy seq/.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina HiSeq 2500", null, "SRP269853", null, null, "DreSceMix_g001_1.fastq.gz", "fastq", 1273185777.0, 24964427.0, "DreSceMix g001 1.fastq.gz", "0:51", "A:541573299;C:186989405;G:191401487;T:353163815;N:57771", 51, null, null, null, 541573299, 186989405, 191401487, 353163815, 57771, "SRX8662781", "SRS6943906", "SRA1094353", "Ryukoku university|Fauculity of Agriculture", "Ryukoku university", 1, 0.62046, null, 0.30937, null, 0.8197, null, 0.44014, null, 51, null, "B", null, "usable mapping rate", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2020-07-03", "Hatching", "Embryo", "Undetermined", "Embryo Imprecise"], [66964, "SRR16965143", "SRX13156592", "SRS11088496", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "1mix", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:10 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :mixture group", "mix 1", "mix 1", "96hpf zebrafish larvae mixture group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "mix2_1_2.fq.gz", "fastq", 3313823250.0, 22092155.0, "mix2 1 2.fq.gz", "0:0 1:150", "A:895726357;C:763402657;G:745765587;T:908922686;N:5963", 0, 150, null, null, 895726357, 763402657, 745765587, 908922686, 5963, "SRX13156592", "SRS11088496", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.93604, null, 0.10794, null, 0.65587, null, 0.47956, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66965, "SRR16965144", "SRX13156591", "SRS11088495", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "3enf", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:9 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :enrofloxacin group", "enf 3", "enf 3", "96hpf zebrafish larvae enrofloxacin group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "enf_3.fq.gz", "fastq", 3304972350.0, 22033149.0, "enf 3.fq.gz", "0:150 1:0", "A:899427202;C:745999066;G:759917309;T:899625137;N:3636", 150, 0, null, null, 899427202, 745999066, 759917309, 899625137, 3636, "SRX13156591", "SRS11088495", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94353, null, 0.10795, null, 0.66212, null, 0.47773, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66967, "SRR16965146", "SRX13156589", "SRS11088492", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "3car", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:6 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :carbendazim group", "car 3", "car 3", "96hpf zebrafish larvae carbendazim group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "car_3_1.fq.gz", "fastq", 3335622150.0, 22237481.0, "car 3 1.fq.gz", "0:150 1:0", "A:853229671;C:807433601;G:820478265;T:854475092;N:5521", 150, 0, null, null, 853229671, 807433601, 820478265, 854475092, 5521, "SRX13156589", "SRS11088492", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.96567, null, 0.03093, null, 0.70997, null, 0.47751, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66968, "SRR16965147", "SRX13156588", "SRS11088494", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "1car", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:4 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :carbendazim group", "car 1", "car 1", "96hpf zebrafish larvae carbendazim group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "car_1_1.fq.gz", "fastq", 3378056400.0, 22520376.0, "car 1 1.fq.gz", "0:150 1:0", "A:886009175;C:795203398;G:809447342;T:887390300;N:6185", 150, 0, null, null, 886009175, 795203398, 809447342, 887390300, 6185, "SRX13156588", "SRS11088494", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.95701, null, 0.05956, null, 0.67836, null, 0.4884, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66969, "SRR16965148", "SRX13156587", "SRS11088491", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "3con", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:3 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :control group", "con 3", "con 3", "96hpf zebrafish larvae control group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "con_3_2.fq.gz", "fastq", 3359054500.0, 33590545.0, "con 3 2.fq.gz", "0:100 1:0", "A:914533337;C:755914202;G:773676246;T:914930715;N:0", 100, 0, null, null, 914533337, 755914202, 773676246, 914930715, 0, "SRX13156587", "SRS11088491", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.95076, null, 0.10478, null, 0.65646, null, 0.49594, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66970, "SRR16965149", "SRX13156586", "SRS11088489", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "3mix", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:12 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :mixture group", "mix 3", "mix 3", "96hpf zebrafish larvae mixture group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "mix2_3_1.fq.gz", "fastq", 3362094000.0, 33620940.0, "mix2 3 1.fq.gz", "0:100 1:0", "A:916124379;C:755910593;G:768246534;T:921812494;N:0", 100, 0, null, null, 916124379, 755910593, 768246534, 921812494, 0, "SRX13156586", "SRS11088489", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94894, null, 0.10416, null, 0.65342, null, 0.49475, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66972, "SRR16965151", "SRX13156584", "SRS11088488", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "2con", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:2 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :control group", "con 2", "con 2", "96hpf zebrafish larvae control group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, "loader:fastq load.py", "con_2_2.fq", "fastq", 3324287550.0, 22161917.0, "con 2 2.fq.gz", "0:150", "A:848766265;C:812477645;G:798995610;T:864040426;N:7604", 150, null, null, null, 848766265, 812477645, 798995610, 864040426, 7604, "SRX13156584", "SRS11088488", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.95546, null, 0.03524, null, 0.70027, null, 0.48649, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-22", "Larval", "Larval", "Undetermined", "Undetermined"], [66973, "SRR16965152", "SRX13156583", "SRS11088487", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "1con", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:1 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :control group", "con 1", "con 1", "96hpf zebrafish larvae control group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, "loader:fastq load.py", "con_1_1.fq", "fastq", 3330724500.0, 22204830.0, "con 1 1.fq.gz", "0:150", "A:896812508;C:762246067;G:774062043;T:897597946;N:5936", 150, null, null, null, 896812508, 762246067, 774062043, 897597946, 5936, "SRX13156583", "SRS11088487", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94926, null, 0.08711, null, 0.66789, null, 0.48628, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-22", "Larval", "Larval", "Undetermined", "Undetermined"], [66975, "SRR16959539", "SRX13151073", "SRS11083379", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "2dim", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:8 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : dimethomorph group", "dim 2", "dim 2", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "dim_2_1.fq.gz", "fastq", 3344257500.0, 22295050.0, "dim 2 1.fq.gz", "0:150 1:0", "A:895700119;C:767415749;G:784994320;T:896143585;N:3727", 150, 0, null, null, 895700119, 767415749, 784994320, 896143585, 3727, "SRX13151073", "SRS11083379", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.9497, null, 0.08418, null, 0.66352, null, 0.49341, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66976, "SRR16959540", "SRX13151072", "SRS11083378", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "1dim", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:7 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : dimethomorph group", "dim 1", "dim 1", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "dim_1_1.fq.gz", "fastq", 3318812250.0, 22125415.0, "dim 1 1.fq.gz", "0:150 1:0", "A:908481293;C:742787936;G:755930542;T:911608821;N:3658", 150, 0, null, null, 908481293, 742787936, 755930542, 911608821, 3658, "SRX13151072", "SRS11083378", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94211, null, 0.11824, null, 0.65344, null, 0.47716, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66977, "SRR16959541", "SRX13151071", "SRS11083377", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "3dif", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:6 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : difenoconazole group", "dif 3", "dif 3", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "dif_3_1.fq.gz", "fastq", 3318453000.0, 22123020.0, "dif 3 1.fq.gz", "0:150 1:0", "A:893975607;C:758489621;G:772391705;T:893592335;N:3732", 150, 0, null, null, 893975607, 758489621, 772391705, 893592335, 3732, "SRX13151071", "SRS11083377", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94838, null, 0.08393, null, 0.66543, null, 0.4818, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66978, "SRR16959542", "SRX13151070", "SRS11083376", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "2dif", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:5 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : difenoconazole group", "dif 2", "dif 2", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "dif_2_2.fq.gz", "fastq", 3304972350.0, 22033149.0, "dif 2 2.fq.gz", "0:0 1:150", "A:890456734;C:764917766;G:744757536;T:904833787;N:6527", 0, 150, null, null, 890456734, 764917766, 744757536, 904833787, 6527, "SRX13151070", "SRS11083376", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.93514, null, 0.107, null, 0.6633, null, 0.47599, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66979, "SRR16959543", "SRX13151069", "SRS11083375", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "1dif", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:4 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : difenoconazole group", "dif 1", "dif 1", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "dif_1_1.fq.gz", "fastq", 3295443900.0, 21969626.0, "dif 1 1.fq.gz", "0:150 1:0", "A:887936493;C:751636494;G:765508757;T:890358629;N:3527", 150, 0, null, null, 887936493, 751636494, 765508757, 890358629, 3527, "SRX13151069", "SRS11083375", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94623, null, 0.09138, null, 0.66478, null, 0.4828, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66980, "SRR16959544", "SRX13151068", "SRS11083374", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "3+con", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:3 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : control group", "con 3", "con 3", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "con_3_1.fq.gz", "fastq", 3306406800.0, 22042712.0, "con 3 1.fq.gz", "0:150 1:0", "A:872740236;C:773482184;G:788334419;T:871846539;N:3422", 150, 0, null, null, 872740236, 773482184, 788334419, 871846539, 3422, "SRX13151068", "SRS11083374", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.95458, null, 0.06103, null, 0.67409, null, 0.48439, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66982, "SRR16959546", "SRX13151066", "SRS11083372", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "2+con", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:2 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : control group", "con 2", "con 2", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "con_2_2.fq.gz", "fastq", 3324287550.0, 22161917.0, "con 2 2.fq.gz", "0:0 1:150", "A:848766265;C:812477645;G:798995610;T:864040426;N:7604", 0, 150, null, null, 848766265, 812477645, 798995610, 864040426, 7604, "SRX13151066", "SRS11083372", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.95548, null, 0.03524, null, 0.70021, null, 0.4867, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66983, "SRR16959547", "SRX13151065", "SRS11083371", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "1+con", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:1 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : control group", "con 1", "con 1", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "con_1_1.fq.gz", "fastq", 3330724500.0, 22204830.0, "con 1 1.fq.gz", "0:150 1:0", "A:896812508;C:762246067;G:774062043;T:897597946;N:5936", 150, 0, null, null, 896812508, 762246067, 774062043, 897597946, 5936, "SRX13151065", "SRS11083371", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94925, null, 0.08711, null, 0.66772, null, 0.48635, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [69604, "SRR18935955", "SRX15013551", "SRS12762156", "SRP372447", "PRJNA832566", "zebrafish RBC sequencing", "PRJNA832566", "Other", "profiling the distinct transcriptional identity of RBC from different RBC related mutants.", null, null, null, null, "alad RBC", null, "strain:alad mutant|dev stage:36 hpf|sex:not collected|tissue:RBC|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of RBC", "L81332", "L81332", "FACS sorted alad mutant RBCs", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP372447", null, null, "Alad-2_L7_I332.R1.clean.fastq.gz", "fastq", 3448675800.0, 22991172.0, "Alad 2 L7 I332.R1.clean.fastq.gz", "0:150 1:0", "A:909204217;C:819708757;G:815883274;T:903292138;N:587414", 150, 0, null, null, 909204217, 819708757, 815883274, 903292138, 587414, "SRX15013551", "SRS12762156", "SRA1410774", "Chinese Acamedy of Sciences|Institute of zoology", "Chinese Acamedy of Sciences", 1, 0.93973, null, 0.13997, null, 0.7685, null, 0.51168, null, 150, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-04-27", "Pharyngula", "Embryo", "Undetermined", "Embryo Imprecise"], [69605, "SRR18935956", "SRX15013550", "SRS12762156", "SRP372447", "PRJNA832566", "zebrafish RBC sequencing", "PRJNA832566", "Other", "profiling the distinct transcriptional identity of RBC from different RBC related mutants.", null, null, null, null, "alad RBC", null, "strain:alad mutant|dev stage:36 hpf|sex:not collected|tissue:RBC|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of RBC", "L81331", "L81331", "FACS sorted alad mutant RBCs", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP372447", null, null, "Alad-1_L8_I331.R1.clean.fastq.gz", "fastq", 3987610500.0, 26584070.0, "Alad 1 L8 I331.R1.clean.fastq.gz", "0:150 1:0", "A:1031398922;C:974521107;G:967367126;T:1013951504;N:371841", 150, 0, null, null, 1031398922, 974521107, 967367126, 1013951504, 371841, "SRX15013550", "SRS12762156", "SRA1410774", "Chinese Acamedy of Sciences|Institute of zoology", "Chinese Acamedy of Sciences", 1, 0.9447, null, 0.1019, null, 0.81286, null, 0.58316, null, 150, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-04-27", "Pharyngula", "Embryo", "Undetermined", "Embryo Imprecise"], [69606, "SRR18935957", "SRX15013549", "SRS12762155", "SRP372447", "PRJNA832566", "zebrafish RBC sequencing", "PRJNA832566", "Other", "profiling the distinct transcriptional identity of RBC from different RBC related mutants.", null, null, null, null, "alas2 RBC", null, "strain:alas2 mutant|dev stage:36 hpf|sex:not collected|tissue:RBC|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of RBC", "L81330", "L81330", "FACS sorted alas2 mutant RBCs", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP372447", null, null, "Alas2-2_L8_I330.R1.clean.fastq.gz", "fastq", 4163915100.0, 27759434.0, "Alas2 2 L8 I330.R1.clean.fastq.gz", "0:150 1:0", "A:1119245849;C:968636914;G:967111308;T:1108544148;N:376881", 150, 0, null, null, 1119245849, 968636914, 967111308, 1108544148, 376881, "SRX15013549", "SRS12762155", "SRA1410774", "Chinese Acamedy of Sciences|Institute of zoology", "Chinese Acamedy of Sciences", 1, 0.92608, null, 0.1778, null, 0.75471, null, 0.55161, null, 150, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-04-27", "Pharyngula", "Embryo", "Undetermined", "Embryo Imprecise"], [69607, "SRR18935958", "SRX15013548", "SRS12762155", "SRP372447", "PRJNA832566", "zebrafish RBC sequencing", "PRJNA832566", "Other", "profiling the distinct transcriptional identity of RBC from different RBC related mutants.", null, null, null, null, "alas2 RBC", null, "strain:alas2 mutant|dev stage:36 hpf|sex:not collected|tissue:RBC|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of RBC", "L81329", "L81329", "FACS sorted alas2 mutant RBCs", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP372447", null, null, "Alas2-1_L8_I329.R1.clean.fastq.gz", "fastq", 3953391150.0, 26355941.0, "Alas2 1 L8 I329.R1.clean.fastq.gz", "0:150 1:0", "A:1035309566;C:950958591;G:946245209;T:1020520823;N:356961", 150, 0, null, null, 1035309566, 950958591, 946245209, 1020520823, 356961, "SRX15013548", "SRS12762155", "SRA1410774", "Chinese Acamedy of Sciences|Institute of zoology", "Chinese Acamedy of Sciences", 1, 0.93024, null, 0.14212, null, 0.81213, null, 0.61442, null, 150, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-04-27", "Pharyngula", "Embryo", "Undetermined", "Embryo Imprecise"], [69608, "SRR18935959", "SRX15013547", "SRS12762154", "SRP372447", "PRJNA832566", "zebrafish RBC sequencing", "PRJNA832566", "Other", "profiling the distinct transcriptional identity of RBC from different RBC related mutants.", null, null, null, null, "WT RBC", null, "strain:WT|dev stage:36 hpf|sex:not collected|tissue:RBC|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of RBC", "L81328", "L81328", "FACS sorted WT RBCs", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP372447", null, null, "WT-2_L8_I328.R1.clean.fastq.gz", "fastq", 3589015200.0, 23926768.0, "WT 2 L8 I328.R1.clean.fastq.gz", "0:150 1:0", "A:922300230;C:887849832;G:879590696;T:898942142;N:332300", 150, 0, null, null, 922300230, 887849832, 879590696, 898942142, 332300, "SRX15013547", "SRS12762154", "SRA1410774", "Chinese Acamedy of Sciences|Institute of zoology", "Chinese Acamedy of Sciences", 1, 0.94576, null, 0.09241, null, 0.83514, null, 0.68592, null, 150, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-04-27", "Pharyngula", "Embryo", "Undetermined", "Embryo Imprecise"], [69609, "SRR18935960", "SRX15013546", "SRS12762154", "SRP372447", "PRJNA832566", "zebrafish RBC sequencing", "PRJNA832566", "Other", "profiling the distinct transcriptional identity of RBC from different RBC related mutants.", null, null, null, null, "WT RBC", null, "strain:WT|dev stage:36 hpf|sex:not collected|tissue:RBC|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of RBC", "L81327", "L81327", "FACS sorted WT RBCs", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP372447", null, null, "WT-1_L8_I327.R1.clean.fastq.gz", "fastq", 4062851700.0, 27085678.0, "WT 1 L8 I327.R1.clean.fastq.gz", "0:150 1:0", "A:1028410873;C:1020911876;G:1010215515;T:1002940085;N:373351", 150, 0, null, null, 1028410873, 1020911876, 1010215515, 1002940085, 373351, "SRX15013546", "SRS12762154", "SRA1410774", "Chinese Acamedy of Sciences|Institute of zoology", "Chinese Acamedy of Sciences", 1, 0.94919, null, 0.0692, null, 0.85567, null, 0.70156, null, 150, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-04-27", "Pharyngula", "Embryo", "Undetermined", "Embryo Imprecise"], [71591, "SRR21773952", "SRX17768899", "SRS15295762", "SRP400510", "PRJNA885753", "Danio rerio Raw sequence reads", "PRJNA885753", "Whole Genome Sequencing", "normal Transcriptome sequencing of zebrafish", null, null, null, null, "ISL 3", null, "strain:AB|breed:fish|age:96 hpf|sex:not applicable|tissue:larvae|replicate:replicate=biological replicate 6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zrbrafish", "ISL 3", "ISL 3", "NORMAL RNA SEQ OF zebrafish", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP400510", null, null, "L1EFH311741--MJ_3.R1.raw.fastq.gz", "fastq", 3636106123.0, 24080173.0, "L1EFH311741  MJ 3.R1.raw.fastq.gz", "0:151 1:0", "A:986029307;C:836470528;G:856224433;T:957306917;N:74938", 151, 0, null, null, 986029307, 836470528, 856224433, 957306917, 74938, "SRX17768899", "SRS15295762", "SRA1510923", "Jiangxi Maternal and Child Health Hospital|Oncology Department", "Jiangxi Maternal and Child Health Hospital", 1, 0.95201, null, 0.07421, null, 0.72995, null, 0.47689, null, 151, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-10-01", "Larval", "Larval", "Undetermined", "Undetermined"], [71592, "SRR21773953", "SRX17768898", "SRS15295761", "SRP400510", "PRJNA885753", "Danio rerio Raw sequence reads", "PRJNA885753", "Whole Genome Sequencing", "normal Transcriptome sequencing of zebrafish", null, null, null, null, "ISL 2", null, "strain:AB|breed:fish|age:96 hpf|sex:not applicable|tissue:larvae|replicate:replicate=biological replicate 5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zrbrafish", "ISL 2", "ISL 2", "NORMAL RNA SEQ OF zebrafish", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP400510", null, null, "L1EFH311740--MJ_2.R1.raw.fastq.gz", "fastq", 4009114024.0, 26550424.0, "L1EFH311740  MJ 2.R1.raw.fastq.gz", "0:151 1:0", "A:1082365671;C:927178308;G:942280451;T:1057206324;N:83270", 151, 0, null, null, 1082365671, 927178308, 942280451, 1057206324, 83270, "SRX17768898", "SRS15295761", "SRA1510923", "Jiangxi Maternal and Child Health Hospital|Oncology Department", "Jiangxi Maternal and Child Health Hospital", 1, 0.93235, null, 0.11003, null, 0.67403, null, 0.46386, null, 151, null, "B", null, "usable mapping rate", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2022-10-01", "Larval", "Larval", "Undetermined", "Undetermined"], [71593, "SRR21773954", "SRX17768897", "SRS15295760", "SRP400510", "PRJNA885753", "Danio rerio Raw sequence reads", "PRJNA885753", "Whole Genome Sequencing", "normal Transcriptome sequencing of zebrafish", null, null, null, null, "ISL 1", null, "strain:AB|breed:fish|age:96 hpf|sex:not applicable|tissue:larvae|replicate:replicate=biological replicate 4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zrbrafish", "ISL 1", "ISL 1", "NORMAL RNA SEQ OF zebrafish", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "SINGLE", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP400510", null, null, "L1EFH311739--MJ_1.R1.raw.fastq.gz", "fastq", 3727259840.0, 24683840.0, "L1EFH311739  MJ 1.R1.raw.fastq.gz", "0:151 1:0", "A:1010831433;C:857231895;G:874029152;T:985090673;N:76687", 151, 0, null, null, 1010831433, 857231895, 874029152, 985090673, 76687, "SRX17768897", "SRS15295760", "SRA1510923", "Jiangxi Maternal and Child Health Hospital|Oncology Department", "Jiangxi Maternal and Child Health Hospital", 1, 0.93354, null, 0.11328, null, 0.67142, null, 0.46153, null, 151, null, "B", null, "usable mapping rate", 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