{"database": "metadata", "table": "run_metadata", "is_view": false, "human_description_en": "where experiment.library_layout = \"PAIRED\", experiment.platform = \"BGISEQ\" and tissue_curation = \"Gonad\"", "rows": [[58533, "SRR11355387", "SRX7957249", "SRS6343356", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C2 3", "C2 3", null, "strain:AB|isolate:C2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C2 320200327", "C2 320200327", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C2_3_1.fq.gz C2_3_2.fq.gz", "fastq fastq", 6857650800.0, 45717672.0, "C2 3 1.fq.gz", "0:150 1:150", "A:1826466263;C:1599272942;G:1580689630;T:1851144875;N:77090", 150, 150, null, null, 1826466263, 1599272942, 1580689630, 1851144875, 77090, "SRX7957249", "SRS6343356", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93222, null, 0.02854, null, 0.75138, null, 0.50759, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58534, "SRR11355388", "SRX7957248", "SRS6343355", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C2 2", "C2 2", null, "strain:AB|isolate:C2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C2 220200326", "C2 220200326", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C2_2_1.fq.gz C2_2_2.fq.gz", "fastq fastq", 6859954800.0, 45733032.0, "C2 2 1.fq.gz", "0:150 1:150", "A:1836618967;C:1591135182;G:1572318102;T:1859806048;N:76501", 150, 150, null, null, 1836618967, 1591135182, 1572318102, 1859806048, 76501, "SRX7957248", "SRS6343355", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93237, null, 0.03248, null, 0.74663, null, 0.5081, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58535, "SRR11355389", "SRX7957247", "SRS6343354", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C2 1", "C2 1", null, "strain:AB|isolate:C2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C2 120200325", "C2 120200325", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C2_1_1.fq.gz C2_1_2.fq.gz", "fastq fastq", 6618974400.0, 44126496.0, "C2 1 1.fq.gz", "0:150 1:150", "A:1774116288;C:1533828286;G:1511526952;T:1799423408;N:79466", 150, 150, null, null, 1774116288, 1533828286, 1511526952, 1799423408, 79466, "SRX7957247", "SRS6343354", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.9326, null, 0.02973, null, 0.75426, null, 0.50678, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58536, "SRR11355390", "SRX7957246", "SRS6343353", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C1 3", "C1 3", null, "strain:AB|isolate:C1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C1 320200324", "C1 320200324", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C1_3_1.fq.gz C1_3_2.fq.gz", "fastq fastq", 6837729600.0, 45584864.0, "C1 3 1.fq.gz", "0:150 1:150", "A:1831266308;C:1587032733;G:1565071069;T:1853950421;N:409069", 150, 150, null, null, 1831266308, 1587032733, 1565071069, 1853950421, 409069, "SRX7957246", "SRS6343353", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93541, null, 0.03212, null, 0.74681, null, 0.50268, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58537, "SRR11355391", "SRX7957245", "SRS6343352", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C1 2", "C1 2", null, "strain:AB|isolate:C1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C1 220200323", "C1 220200323", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C1_2_2.fq.gz C1_2_1.fq.gz", "fastq fastq", 6860328000.0, 45735520.0, "C1 2 1.fq.gz", "0:150 1:150", "A:1838176072;C:1591277709;G:1569605888;T:1861063734;N:204597", 150, 150, null, null, 1838176072, 1591277709, 1569605888, 1861063734, 204597, "SRX7957245", "SRS6343352", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93763, null, 0.033, null, 0.74617, null, 0.50287, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58538, "SRR11355392", "SRX7957244", "SRS6343351", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C1 1", "C1 1", null, "strain:AB|isolate:C1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C1 120200322", "C1 120200322", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C1_1_1.fq.gz C1_1_2.fq.gz", "fastq fastq", 6865547700.0, 45770318.0, "C1 1 1.fq.gz", "0:150 1:150", "A:1841774713;C:1591288582;G:1570400871;T:1861867728;N:215806", 150, 150, null, null, 1841774713, 1591288582, 1570400871, 1861867728, 215806, "SRX7957244", "SRS6343351", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93567, null, 0.03152, null, 0.74653, null, 0.50239, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58539, "SRR11355393", "SRX7957243", "SRS6343350", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C0 3", "C0 3", null, "strain:AB|isolate:C0|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C0 320200321", "C0 320200321", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C0_3_1.fq.gz C0_3_2.fq.gz", "fastq fastq", 6824622600.0, 45497484.0, "C0 3 1.fq.gz", "0:150 1:150", "A:1833660953;C:1578510104;G:1558095174;T:1854128169;N:228200", 150, 150, null, null, 1833660953, 1578510104, 1558095174, 1854128169, 228200, "SRX7957243", "SRS6343350", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93758, null, 0.0323, null, 0.75024, null, 0.50852, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58540, "SRR11355394", "SRX7957242", "SRS6343349", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C0 2", "C0 2", null, "strain:AB|isolate:C0|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C0 220200320", "C0 220200320", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C0_2_2.fq.gz C0_2_1.fq.gz", "fastq fastq", 6819326400.0, 45462176.0, "C0 2 1.fq.gz", "0:150 1:150", "A:1837661215;C:1571877614;G:1550458835;T:1859103408;N:225328", 150, 150, null, null, 1837661215, 1571877614, 1550458835, 1859103408, 225328, "SRX7957242", "SRS6343349", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93697, null, 0.0339, null, 0.74793, null, 0.5035, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [58541, "SRR11355395", "SRX7957241", "SRS6343348", "SRP253408", "PRJNA613558", "Transcriptomic assessments RNA sequencing in ovaries following treatments of gravid female zebrafish to an antibiotic mixture", "PRJNA613558", "Other", "As the use of antimicrobials during pregnancy and the perinatal period may lead to adverse outcomes such as miscarriages and newborn disease  the purpose of present study was to evaluate the influence of antibiotic exposure in offspring following treatments of gravid female zebrafish to an antibiotic mixture. For the F0 generation  adult zebrafish AB strain at sexual maturity 150 dpf dpf were selected for experimentation 50% male and 50% pregnant female. Given a significant change occurred in eggs production and F1 survival at birth in present study  combined with antibiotics bioaccumulated in ovary  we suspect that antibiotic exposure might impact the ovary of F0 generation zebrafish  and thus affect egg production and survival. Therefore  ovaries of the F0 generation were evaluated for transcriptional effects in different antibiotics mixture exposure 0  1 and 100 ug/L using a HTS approach coupled with advanced bioinformatic tools.", null, null, null, "C0 1", "C0 1", null, "strain:AB|isolate:C0|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:not applicable|dev stage:not applicable|sex:female|tissue:ovary|collection date:2019 11 01|geo loc name:China: Shenzhen Guangdong|replicate:biological replicate 1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish", "C0 120200319", "C0 120200319", "RNA seq of zebrafish in different conditions", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "RANDOM PCR", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP253408", null, null, "C0_1_1.fq.gz C0_1_2.fq.gz", "fastq fastq", 7030804800.0, 46872032.0, "C0 1 1.fq.gz", "0:150 1:150", "A:1891469955;C:1624531422;G:1603124564;T:1911444454;N:234405", 150, 150, null, null, 1891469955, 1624531422, 1603124564, 1911444454, 234405, "SRX7957241", "SRS6343348", "SRA1056819", "Southern University of Science and Technology|School of Environmental Science and Engineering", "Southern University of Science and Technology", 1, 0.93519, null, 0.0328, null, 0.74602, null, 0.48272, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "random_priming", "unknown", "bulk", "unknown", "unknown", null, "China", "2020-03-20", "Undetermined", "Adult", "Gonad", "Reproductive System"], [74160, "SRR23576624", "SRX19463433", "SRS16856056", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T1B", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert no Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T1B", "T1B", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T1B_1.fq.gz T1B_2.fq.gz", "fastq fastq", 12301883400.0, 123018834.0, "T1B 1.fq.gz", "0:100 1:100", "A:3241228917;C:2853095411;G:2904960052;T:3302599020;N:0", 100, 100, null, null, 3241228917, 2853095411, 2904960052, 3302599020, 0, "SRX19463433", "SRS16856056", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95272, null, 0.09396, null, 0.68469, null, 0.54489, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74177, "SRR23576641", "SRX19463416", "SRS16856039", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T9", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T9", "T9", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T9_1.fq.gz T9_2.fq.gz", "fastq fastq", 12386772800.0, 123867728.0, "T9 1.fq.gz", "0:100 1:100", "A:3400599530;C:2772066139;G:2813890387;T:3400216744;N:0", 100, 100, null, null, 3400599530, 2772066139, 2813890387, 3400216744, 0, "SRX19463416", "SRS16856039", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.93775, null, 0.12024, null, 0.63838, null, 0.49765, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74178, "SRR23576642", "SRX19463415", "SRS16856037", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. 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However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T7", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T7", "T7", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T7_1.fq.gz T7_2.fq.gz", "fastq fastq", 12172655600.0, 121726556.0, "T7 1.fq.gz", "0:100 1:100", "A:3248593263;C:2809119242;G:2855399333;T:3259543762;N:0", 100, 100, null, null, 3248593263, 2809119242, 2855399333, 3259543762, 0, "SRX19463414", "SRS16856038", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94602, null, 0.10229, null, 0.63603, null, 0.48805, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74180, "SRR23576644", "SRX19463413", "SRS16856036", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T6", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert Cre R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T6", "T6", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T6_1.fq.gz T6_2.fq.gz", "fastq fastq", 12378860000.0, 123788600.0, "T6 1.fq.gz", "0:100 1:100", "A:3314969512;C:2848487369;G:2903637904;T:3311765215;N:0", 100, 100, null, null, 3314969512, 2848487369, 2903637904, 3311765215, 0, "SRX19463413", "SRS16856036", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94452, null, 0.10777, null, 0.62422, null, 0.49742, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74181, "SRR23576645", "SRX19463412", "SRS16856034", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T5", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert Cre R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T5", "T5", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T5_1.fq.gz T5_2.fq.gz", "fastq fastq", 12128636200.0, 121286362.0, "T5 1.fq.gz", "0:100 1:100", "A:3365971947;C:2671909728;G:2726788212;T:3363966313;N:0", 100, 100, null, null, 3365971947, 2671909728, 2726788212, 3363966313, 0, "SRX19463412", "SRS16856034", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.93852, null, 0.14946, null, 0.63747, null, 0.52613, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74182, "SRR23576646", "SRX19463411", "SRS16856032", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T4", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T4", "T4", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T4_1.fq.gz T4_2.fq.gz", "fastq fastq", 12162901400.0, 121629014.0, "T4 1.fq.gz", "0:100 1:100", "A:3278648055;C:2767244505;G:2825703918;T:3291304922;N:0", 100, 100, null, null, 3278648055, 2767244505, 2825703918, 3291304922, 0, "SRX19463411", "SRS16856032", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94511, null, 0.11642, null, 0.63258, null, 0.4913, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74183, "SRR23576647", "SRX19463410", "SRS16856035", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T3", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert no Cre R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T3", "T3", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T3_1.fq.gz T3_2.fq.gz", "fastq fastq", 12163321600.0, 121633216.0, "T3 1.fq.gz", "0:100 1:100", "A:3285334843;C:2767357208;G:2816394061;T:3294235488;N:0", 100, 100, null, null, 3285334843, 2767357208, 2816394061, 3294235488, 0, "SRX19463410", "SRS16856035", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.9415, null, 0.11969, null, 0.62666, null, 0.50292, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74184, "SRR23576648", "SRX19463409", "SRS16856033", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. 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Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T2B", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert no Cre R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T2B", "T2B", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T2B_1.fq.gz T2B_2.fq.gz", "fastq fastq", 12317978600.0, 123179786.0, "T2B 1.fq.gz", "0:100 1:100", "A:3182137355;C:2913584264;G:2974241242;T:3248015739;N:0", 100, 100, null, null, 3182137355, 2913584264, 2974241242, 3248015739, 0, "SRX19463409", "SRS16856033", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of 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