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We have performed extensive expression analysis and chromatin accessibility assays on endothelial and hemogenic endothelial cells in knockdown animals for all the RLR receptors. Additionally we did expression analysis on animals with knockdown of two receptors. 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We have performed extensive expression analysis and chromatin accessibility assays on endothelial and hemogenic endothelial cells in knockdown animals for all the RLR receptors. Additionally we did expression analysis on animals with knockdown of two receptors. 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We have performed extensive expression analysis and chromatin accessibility assays on endothelial and hemogenic endothelial cells in knockdown animals for all the RLR receptors. Additionally we did expression analysis on animals with knockdown of two receptors. Finally we examined the upregulation of repetitive elements in hemogenic endothelial cells post treatment with valproic acid VPA or decitabine.", null, null, null, null, "danRer10 raw data", null, "strain:AB/tu|age:not applicable|sex:pooled male and female|tissue:endothelial and hemogenic endothelial|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq decitabine treatment in hemogenic endothelial cell 26hpf replicate 1", "23", "23", "NEBNext Low Input RNA Library Prep Kit", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "size fractionation", "PAIRED", "ILLUMINA", "Illumina HiSeq 3000", null, "SRP226614", null, null, "RNA_seq decitabine treatment in hemogenic endothelial cell 26hpf replicate 1_R1.fastq.gz RNA_seq decitabine treatment in hemogenic endothelial cell 26hpf replicate 1_R2.fastq.gz", "fastq fastq", 5656815000.0, 37712100.0, "RNA seq decitabine treatment in hemogenic endothelial cell 26hpf replicate 1 R1.fastq.gz", "0:75 1:75", "A:1487198866;C:1332723090;G:1275197163;T:1514410765;N:47285116", 75, 75, null, null, 1487198866, 1332723090, 1275197163, 1514410765, 47285116, "SRX7034698", "SRS5554730", "SRA983011", "Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany|Department of Cellular and Molecular Immunology", "Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany", 2, 0.86399, 0.76012, 0.0587, 0.05779, 0.76461, 0.9105, 0.49754, 0.51037, 75, 75, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "size_fractionation", "nebnext", "bulk", "unknown", "unknown", null, "Germany", "2019-10-24", "Pharyngula", "Embryo", "Endothelium", "Cardiovascular System"], [55388, "SRR10323900", "SRX7034697", "SRS5554730", "SRP226614", "PRJNA578896", "Repetitive elements engage Rig I and Mda5 in interplay with Lgp2 to enhance hematopoietic stem cell emergence", "PRJNA578896", "Other", "In this study we examine the role of RIG I like receptors RLRs in hematopoietic stem and progenitor cell formation. We have performed extensive expression analysis and chromatin accessibility assays on endothelial and hemogenic endothelial cells in knockdown animals for all the RLR receptors. Additionally we did expression analysis on animals with knockdown of two receptors. Finally we examined the upregulation of repetitive elements in hemogenic endothelial cells post treatment with valproic acid VPA or decitabine.", null, null, null, null, "danRer10 raw data", null, "strain:AB/tu|age:not applicable|sex:pooled male and female|tissue:endothelial and hemogenic endothelial|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq  VPA treatment in hemogenic endothelial cell 26hpf replicate 2", "22", "22", "NEBNext Low Input RNA Library Prep Kit", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "size fractionation", "PAIRED", "ILLUMINA", "Illumina HiSeq 3000", null, "SRP226614", null, null, "RNA_seq VPA treatment in hemogenic endothelial cell 26hpf replicate 2_R2.fastq.gz RNA_seq VPA treatment in hemogenic endothelial cell 26hpf replicate 2_R1.fastq.gz", "fastq fastq", 5978780250.0, 39858535.0, "RNA seq VPA treatment in hemogenic endothelial cell 26hpf replicate 2 R1.fastq.gz", "0:75 1:75", "A:1580804547;C:1404640964;G:1399714637;T:1593586843;N:33259", 75, 75, null, null, 1580804547, 1404640964, 1399714637, 1593586843, 33259, "SRX7034697", "SRS5554730", "SRA983011", "Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany|Department of Cellular and Molecular Immunology", "Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany", 2, 0.92216, 0.92477, 0.04155, 0.04126, 0.74537, 0.7512, 0.48148, 0.49049, 75, 75, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "size_fractionation", "nebnext", "bulk", "unknown", "unknown", null, "Germany", "2019-10-24", "Pharyngula", "Embryo", "Endothelium", "Cardiovascular System"], [55389, "SRR10323901", "SRX7034696", "SRS5554730", "SRP226614", "PRJNA578896", "Repetitive elements engage Rig I and Mda5 in interplay with Lgp2 to enhance hematopoietic stem cell emergence", "PRJNA578896", "Other", "In this study we examine the role of RIG I like receptors RLRs in hematopoietic stem and progenitor cell formation. We have performed extensive expression analysis and chromatin accessibility assays on endothelial and hemogenic endothelial cells in knockdown animals for all the RLR receptors. Additionally we did expression analysis on animals with knockdown of two receptors. 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We have performed extensive expression analysis and chromatin accessibility assays on endothelial and hemogenic endothelial cells in knockdown animals for all the RLR receptors. Additionally we did expression analysis on animals with knockdown of two receptors. 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"primary_keys": [], "units": {}, "query": {"sql": "select rowid, [run.accession], [experiment.accession], [sample.accession], [study.accession], bioproject, [study.title], [study.alias], [study.type], [study.abstract], [study.attributes], [study.PMIDs], [sample.description], [sample.title], [sample.alias], [sample.centername], [sample.attributes], [GEOsample.title], [GEOsample.dataprocessing], [GEOsample.source], [GEOsample.treatmentprotocol], [GEOsample.extractprotocol], [GEOsample.growthprotocol], [GEOsample.characteristics], [GEOsample.accession], [experiment.title], [experiment.alias], [experiment.library_name], [experiment.design_description], [experiment.library_construction_protocol], [experiment.attributes], [experiment.library_strategy], [experiment.library_source], [experiment.library_selection], [experiment.library_layout], [experiment.platform], [experiment.instrument_model], [experiment.spot_descriptor], [experiment.study_ref], [run.title], [run.attributes], [run.filename], [run.semantic_name], [run.total_bases], [run.total_spots], [run.alias], [run.read_lengths], [run.base_counts], [run.r1_length], [run.r2_length], [run.r3_length], [run.r4_length], [run.Acount], [run.Ccount], [run.Gcount], [run.Tcount], [run.Ncount], [run.experiment], [run.pool_member], [submission.accession], [submission.srasource], [submission.bioprojectsource], [seqdetective.n_mates], [seqdetective.mapping_rate.mate1], [seqdetective.mapping_rate.mate2], [seqdetective.nofeature_rate.mate1], [seqdetective.nofeature_rate.mate2], [seqdetective.sparsity.mate1], [seqdetective.sparsity.mate2], [seqdetective.pos_strand_rate.mate1], [seqdetective.pos_strand_rate.mate2], [seqdetective.readlen.mate1], [seqdetective.readlen.mate2], [seqdetective.judgement.mate1], [seqdetective.judgement.mate2], [seqdetective.judgement.reason], platform_family, instrument_generation, read_bias, selection_class, prep_kit, sc_or_bulk, tech_class, technology, tech_variant, [submission.bioprojectsource.country], earliest_date, devstage_curation, devstage_curation_coarse, tissue_curation, tissue_curation_coarse from run_metadata where \"experiment.library_layout\" = :p0 and \"experiment.library_selection\" = :p1 and \"tissue_curation_coarse\" = :p2 order by rowid limit 101", "params": {"p0": "PAIRED", "p1": "size fractionation", "p2": "Cardiovascular System"}}, "facet_results": {"experiment.library_strategy": {"name": "experiment.library_strategy", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "RNA-Seq", "label": "RNA-Seq", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&experiment.library_strategy=RNA-Seq", "selected": false}], "truncated": false}, "experiment.library_source": {"name": "experiment.library_source", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "TRANSCRIPTOMIC", "label": "TRANSCRIPTOMIC", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&experiment.library_source=TRANSCRIPTOMIC", "selected": false}], "truncated": false}, "experiment.library_selection": {"name": "experiment.library_selection", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "size fractionation", "label": "size fractionation", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&tissue_curation_coarse=Cardiovascular+System", "selected": true}], "truncated": false}, "experiment.library_layout": {"name": "experiment.library_layout", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "PAIRED", "label": "PAIRED", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "selected": true}], "truncated": false}, "experiment.platform": {"name": "experiment.platform", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "ILLUMINA", "label": "ILLUMINA", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&experiment.platform=ILLUMINA", "selected": false}], "truncated": false}, "devstage_curation_coarse": {"name": "devstage_curation_coarse", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "Embryo", "label": "Embryo", "count": 24, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&devstage_curation_coarse=Embryo", "selected": false}, {"value": "Undetermined", "label": "Undetermined", "count": 6, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&devstage_curation_coarse=Undetermined", "selected": false}], "truncated": false}, "devstage_curation": {"name": "devstage_curation", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "Pharyngula", "label": "Pharyngula", "count": 24, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&devstage_curation=Pharyngula", "selected": false}, {"value": "Undetermined", "label": "Undetermined", "count": 6, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&devstage_curation=Undetermined", "selected": false}], "truncated": false}, "tissue_curation_coarse": {"name": "tissue_curation_coarse", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "Cardiovascular System", "label": "Cardiovascular System", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation", "selected": true}], "truncated": false}, "tissue_curation": {"name": "tissue_curation", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "Endothelium", "label": "Endothelium", "count": 24, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&tissue_curation=Endothelium", "selected": false}, {"value": "Heart", "label": "Heart", "count": 6, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&tissue_curation=Heart", "selected": false}], "truncated": false}, "technology": {"name": "technology", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System", "results": [{"value": "unknown", "label": "unknown", "count": 30, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?experiment.library_layout=PAIRED&experiment.library_selection=size+fractionation&tissue_curation_coarse=Cardiovascular+System&technology=unknown", "selected": false}], "truncated": false}}, "suggested_facets": [], "next": null, "next_url": null, "private": false, "allow_execute_sql": true, "query_ms": 65.78568999975687}