{"database": "metadata", "table": "run_metadata", "is_view": false, "human_description_en": "where experiment.library_layout = \"PAIRED\", experiment.library_selection = \"Oligo-dT\" and experiment.platform = \"BGISEQ\"", "rows": [[31825, "SRR28700412", "SRX24268115", "SRS21034395", "SRP501894", "PRJNA1100624", "Functions of Epimedin C in a zebrafish model of glucocorticoid induced osteoporosis", "PRJNA1100624", "Other", "Research indicates that Epimedin C EC  an active compound in Epimedium  offers a potential treatment for glucocorticoid induced osteoporosis GIOP. Studies on zebrafish larvae revealed that EC treatment enhances bone mineralization  increases bone mass  and improves bone density  thus mitigating bone tissue damage caused by prednisolone. Additionally  EC impacts key signaling pathways related to bone development  such as osteoclast differentiation  estrogen  MAPK  insulin resistance  PPAR  and AMPK pathways. 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This study highlights EC's role in bone health and its promising osteoprotective effects  presenting it as a viable  cost effective treatment for GIOP.", null, null, null, null, "Control 1", null, "isolate:con1|age:9dpf|collection date:2023 07 13|geo loc name:China:Hubei Xiangyang|sex:not collected|tissue:animal sample|replicate:replicate = biological replicate 1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "Control 1", "Control 1", "Total RNA undergoes mRNA enrichment  reverse transcription  adapter ligation  PCR amplification  and circularization into a single stranded DNA library.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP501894", null, null, "Control_1_1.fq.gz Control_1_2.fq.gz", "fastq fastq", 6720214500.0, 22400715.0, "Control 1 1.fq.gz", "0:150 1:150", "A:1814883015;C:1537948710;G:1559376116;T:1808006659;N:0", 150, 150, null, null, 1814883015, 1537948710, 1559376116, 1808006659, 0, "SRX24268104", "SRS21034384", null, null, "Xiangyang No.1 People's Hospital, Hubei University of Medicine", null, null, null, null, null, null, null, null, null, null, null, "B", "B", "biological fallback assumption", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2024-04-15", "Larval", "Larval", "Undetermined", "Undetermined"], [55643, "SRR10604044", "SRX7283593", "SRS5777402", "SRP235014", "PRJNA594101", "Danio rerio Transcriptome", "PRJNA594101", "Other", "Danio rerio Transcriptome post cGAS and STING knockout", null, null, null, null, "stko2", null, "strain:not collected|isolate:sting knockout 2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebraish larvae", "sting knockout 2", "sting knockout 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null, "stko1", null, "strain:not collected|isolate:sting knockout 1|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebraish larvae", "sting knockout 1", "sting knockout 1", "RNA seq", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP235014", null, null, "stko1_1.fastq.gz stko1_2.fastq.gz", "fastq fastq", 10453959000.0, 69693060.0, "stko1 1.fastq.gz", "0:150 1:150", "A:2823253748;C:2400078679;G:2379662427;T:2850274552;N:689594", 150, 150, null, null, 2823253748, 2400078679, 2379662427, 2850274552, 689594, "SRX7283592", "SRS5777401", "SRA1007465", "Shantou university medical college|Neuroscience Center", "Shantou university medical college", 1, 0.92736, null, 0.08475, null, 0.69822, null, 0.47233, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2019-12-08", "Larval", "Larval", "Undetermined", "Undetermined"], [55645, "SRR10604046", "SRX7283591", "SRS5777400", "SRP235014", "PRJNA594101", "Danio rerio Transcriptome", "PRJNA594101", "Other", "Danio rerio Transcriptome post cGAS and STING knockout", null, null, null, null, "cgko2", null, "strain:not collected|isolate:cgas knockout 2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebraish larvae", "cgas knockout 2", "cgas knockout 2", "RNA seq", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP235014", null, null, "cgko2_1.fastq.gz cgko2_2.fastq.gz", "fastq fastq", 10462236900.0, 69748246.0, "cgko2 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"SRX7283589", "SRS5777398", "SRP235014", "PRJNA594101", "Danio rerio Transcriptome", "PRJNA594101", "Other", "Danio rerio Transcriptome post cGAS and STING knockout", null, null, null, null, "wt2", null, "strain:not collected|isolate:normal 2|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:7 days|dev stage:larvae|sex:not applicable|tissue:larvae|biomaterial provider:Yang xiaojun|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebraish larvae", "wt normal 2", "wt normal 2", "RNA seq", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP235014", null, null, "wt2_1.fastq.gz wt2_2.fastq.gz", "fastq fastq", 10660916400.0, 71072776.0, "wt2 1.fastq.gz", "0:150 1:150", "A:2906473511;C:2417423798;G:2405111864;T:2931146507;N:760720", 150, 150, null, null, 2906473511, 2417423798, 2405111864, 2931146507, 760720, "SRX7283589", "SRS5777398", "SRA1007465", "Shantou university 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transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.", null, null, "END OF 21 DAY RECOVERY", null, "R01", null, "strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:control|SAMPLING TIME:END OF 21 DAY RECOVERY|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult female brain", "R01", "R01", "a standardized procedure at the Beijing Genome Institute", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP335395", null, null, "R01_1.fq.gz R01_2.fq.gz", "fastq fastq", 6781182900.0, 45207886.0, "R01 1.fq.gz", "0:150 1:150", "A:1988991157;C:1393829563;G:1402027963;T:1996312981;N:21236", 150, 150, null, null, 1988991157, 1393829563, 1402027963, 1996312981, 21236, "SRX11996477", "SRS10003992", "SRA1288076", "Jiangsu University|Institute of Environmental Health and Ecological S", "Jiangsu University", 1, 0.91278, null, 0.20165, null, 0.71054, null, 0.54354, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-09-02", "Adult", "Adult", "Brain", "Nervous System"], [65945, "SRR15700566", "SRX11996476", "SRS10003991", "SRP335395", "PRJNA759881", "Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio", "PRJNA759881", "Other", "Following exposure to Amitriptyline AMI for 7 days E7  zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.", null, null, "END OF 7 DAY EXPOSURE", null, "EH3", null, "strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 3|treatment:AMI 40.0|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult female brain", "EH3", "EH3", "a standardized procedure at the Beijing Genome Institute", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP335395", null, null, "EH3_1.fq.gz EH3_2.fq.gz", "fastq fastq", 6798939900.0, 45326266.0, "EH3 1.fq.gz", "0:150 1:150", "A:1958992563;C:1429773625;G:1441958341;T:1968192397;N:22974", 150, 150, null, null, 1958992563, 1429773625, 1441958341, 1968192397, 22974, "SRX11996476", "SRS10003991", "SRA1288076", "Jiangsu University|Institute of Environmental Health and Ecological S", "Jiangsu University", 1, 0.91681, null, 0.18245, null, 0.7083, null, 0.5369, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-09-02", "Adult", "Adult", "Brain", "Nervous System"], [65946, "SRR15700567", "SRX11996475", "SRS10003990", "SRP335395", "PRJNA759881", "Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio", "PRJNA759881", "Other", "Following exposure to Amitriptyline AMI for 7 days E7  zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.", null, null, "END OF 7 DAY EXPOSURE", null, "EH2", null, "strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:AMI 40.0|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult female brain", "EH2", "EH2", "a standardized procedure at the Beijing Genome Institute", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP335395", null, null, "EH2_1.fq.gz EH2_2.fq.gz", "fastq fastq", 6792825900.0, 45285506.0, "EH2 1.fq.gz", "0:150 1:150", "A:1958355652;C:1427389031;G:1440081079;T:1966978334;N:21804", 150, 150, null, null, 1958355652, 1427389031, 1440081079, 1966978334, 21804, "SRX11996475", "SRS10003990", "SRA1288076", "Jiangsu University|Institute of Environmental Health and Ecological S", "Jiangsu University", 1, 0.91907, null, 0.17888, null, 0.70575, null, 0.54118, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-09-02", "Adult", "Adult", "Brain", "Nervous System"], [65947, "SRR15700568", "SRX11996474", "SRS10003989", "SRP335395", "PRJNA759881", "Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio", "PRJNA759881", "Other", "Following exposure to Amitriptyline AMI for 7 days E7  zebrafish were transferred into AMI free water to recover for 21 days R21. Brain transcriptional profiles were investigated on E7 and R21.", null, null, "END OF 7 DAY EXPOSURE", null, "EH1", null, "strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 1|treatment:AMI 40.0|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult female brain", "EH1", "EH1", "a standardized procedure at the Beijing Genome Institute", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP335395", null, null, "EH1_1.fq.gz EH1_2.fq.gz", "fastq fastq", 6723154200.0, 44821028.0, "EH1 1.fq.gz", "0:150 1:150", "A:1939940725;C:1412087358;G:1424339686;T:1946764075;N:22356", 150, 150, null, null, 1939940725, 1412087358, 1424339686, 1946764075, 22356, "SRX11996474", "SRS10003989", "SRA1288076", "Jiangsu University|Institute of Environmental Health and Ecological S", "Jiangsu University", 1, 0.91848, null, 0.1756, null, 0.71293, null, 0.54795, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-09-02", "Adult", "Adult", "Brain", "Nervous System"], [65948, "SRR15700569", "SRX11996473", "SRS10003988", "SRP335395", "PRJNA759881", "Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio", "PRJNA759881", "Other", "Following exposure to Amitriptyline AMI for 7 days E7  zebrafish were transferred into AMI free water to recover for 21 days R21. 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Brain transcriptional profiles were investigated on E7 and R21.", null, null, "END OF 7 DAY EXPOSURE", null, "EL2", null, "strain:AB|age:4 MONTHS|dev stage:Adult|sex:female|tissue:brain|replicate:replicate = biological replicate 2|treatment:AMI 2.5|SAMPLING TIME:END OF 7 DAY EXPOSURE|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio: adult female brain", "EL2", "EL2", "a standardized procedure at the Beijing Genome Institute", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP335395", null, null, "EL2_1.fq.gz EL2_2.fq.gz", "fastq fastq", 6811200600.0, 45408004.0, "EL2 1.fq.gz", "0:150 1:150", "A:1961542081;C:1433135536;G:1446857456;T:1969644200;N:21327", 150, 150, null, null, 1961542081, 1433135536, 1446857456, 1969644200, 21327, "SRX11996472", "SRS10003987", "SRA1288076", "Jiangsu University|Institute of Environmental Health and Ecological S", "Jiangsu University", 1, 0.91853, null, 0.17639, null, 0.71076, null, 0.54175, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-09-02", "Adult", "Adult", "Brain", "Nervous System"], [65950, "SRR15700571", "SRX11996471", "SRS10003986", "SRP335395", "PRJNA759881", "Persistent Impact of Short term Amitriptyline Exposure on brain Transcriptional Profile of Zebrafish Danio rerio", "PRJNA759881", "Other", "Following exposure to Amitriptyline AMI for 7 days E7  zebrafish were transferred into AMI free water to recover for 21 days R21. 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carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "1enf", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:7 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :enrofloxacin group", "enf 1", "enf 1", "96hpf zebrafish larvae enrofloxacin group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "enf_1.fq.gz enf_2.fq.gz", "fastq fastq", 6652389300.0, 44349262.0, "enf 1.fq.gz", "0:150 1:150", "A:1759651033;C:1563446116;G:1556912596;T:1772370048;N:9507", 150, 150, null, null, 1759651033, 1563446116, 1556912596, 1772370048, 9507, "SRX13156590", "SRS11088493", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.94992, null, 0.06316, null, 0.66979, null, 0.48987, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66971, "SRR16965150", "SRX13156585", "SRS11088490", "SRP346547", "PRJNA780808", "transcriptomics of carbendazim and enrofloxacin on zebrafish embryos", "PRJNA780808", "Other", "reveal a interaction between ENF and CAR on metabolic regulation during development", null, null, null, null, "2mix", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:11 96hpf|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio :mixture group", "mix 2", "mix 2", "96hpf zebrafish larvae mixture group", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP346547", null, null, "car_2_2.fq.gz mix2_2_1.fq.gz", "fastq fastq", 6669719100.0, 44464794.0, "car 2 2.fq.gz", "0:150 1:150", "A:1815824677;C:1515086864;G:1506360115;T:1832433148;N:14296", 150, 150, null, null, 1815824677, 1515086864, 1506360115, 1832433148, 14296, "SRX13156585", "SRS11088490", "SRA1329868", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.93884, null, 0.11657, null, 0.65527, null, 0.48114, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-17", "Larval", "Larval", "Undetermined", "Undetermined"], [66974, "SRR16959538", "SRX13151074", "SRS11083380", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "1+mix", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:10 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : mixture group", "mix 1", "mix 1", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "mix1_3_2.fq.gz mix1_1_1.fq.gz", "fastq fastq", 6639699600.0, 44264664.0, "mix1 1 1.fq.gz", "0:150 1:150", "A:1738687157;C:1575344731;G:1569683716;T:1755974708;N:9288", 150, 150, null, null, 1738687157, 1575344731, 1569683716, 1755974708, 9288, "SRX13151074", "SRS11083380", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.95161, null, 0.05697, null, 0.6817, null, 0.48485, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [66981, "SRR16959545", "SRX13151067", "SRS11083373", "SRP346418", "PRJNA780940", "transcriptomics of difenoconazole and dimethomorph on zebrafish embryos", "PRJNA780940", "Other", "Difenoconazole DIF and dimethomorph DIM are widely used pesticides frequently detected together in environmental samples  so the deleterious effects of combined exposure warrant detailed examination. In this study  the individual and combined effects of DIM and DIF on conventional developmental parameters hatch rate  deformity rate  lethality and gene expression were measured in embryonic zebrafish. Both DIF and DIM interfered with normal zebrafish embryo development  and the most sensitive toxicity index for both was 96 hpf deformity rate BMDL10 values of 0.30 and 1.10 mg/L  respectively. The combination of DIF and DIM had mainly synergistic deleterious effects on 96 hpf deformity and mortality rates. Transcriptome analysis showed that these compounds markedly downregulated expression of mcm family genes  cdk1  and cdc20  thereby potentially disrupting DNA replication and cell cycle progression. Enhanced surveillance for this pesticide combination is recommended as simultaneous environmental exposure may be substantially more harmful than exposure to either compound alone.", null, null, null, null, "2+mix", null, "strain:Tu|isolate:N/A|breed:N/A|cultivar:N/A|ecotype:N/A|age:11 96h|dev stage:larvae|sex:male and female|tissue:larvae|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : mixture group", "mix 2", "mix 2", "The final library was amplified with phi29 to make DNA nanoballs DNB  with more than 300 copies of one molecular.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP346418", null, null, "mix1_2_1.fq.gz dim_3_2.fq.gz", "fastq fastq", 6589866900.0, 43932446.0, "dim 3 2.fq.gz", "0:150 1:150", "A:1782755416;C:1508342477;G:1501934674;T:1796820276;N:14057", 150, 150, null, null, 1782755416, 1508342477, 1501934674, 1796820276, 14057, "SRX13151067", "SRS11083373", "SRA1330365", "China Agricultural University|College of animal science and technology", "China Agricultural University", 1, 0.93861, null, 0.10685, null, 0.66393, null, 0.47194, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2021-11-16", "Larval", "Larval", "Undetermined", "Undetermined"], [67884, "SRR17868935", "SRX14028691", "SRS11864778", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C4 1", null, "strain:danio rerio AgNPs4|breed:zebrafish10|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 4 1", "AG 4 1", "AG 4 1", "treatment7", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C4-1_1.fq.gz C4-1_2.fq.gz", "fastq fastq", 6830916900.0, 45539446.0, "C4 1 1.fq.gz", "0:150 1:150", "A:2011586443;C:1405775454;G:1388504965;T:2024992696;N:57342", 150, 150, null, null, 2011586443, 1405775454, 1388504965, 2024992696, 57342, "SRX14028691", "SRS11864778", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.92344, null, 0.21929, null, 0.71043, null, 0.46315, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67885, "SRR17868936", "SRX14028690", "SRS11864777", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C2 3", null, "strain:danio rerio AgNPs2|breed:zebrafish9|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 2 3", "AG 2 3", "AG 2 3", "treatment6", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C2-3_1.fq.gz C2-3_2.fq.gz", "fastq fastq", 6782959200.0, 45219728.0, "C2 3 1.fq.gz", "0:150 1:150", "A:1949560199;C:1443524899;G:1428814233;T:1960921903;N:137966", 150, 150, null, null, 1949560199, 1443524899, 1428814233, 1960921903, 137966, "SRX14028690", "SRS11864777", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.93181, null, 0.17739, null, 0.6927, null, 0.50528, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67886, "SRR17868937", "SRX14028689", "SRS11864776", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C2 2", null, "strain:danio rerio AgNPs2|breed:zebrafish8|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 2 2", "AG 2 2", "AG 2 2", "treatment5", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C2-2_1.fq.gz C2-2_2.fq.gz", "fastq fastq", 6817863300.0, 45452422.0, "C2 2 1.fq.gz", "0:150 1:150", "A:1964890519;C:1446826412;G:1428708103;T:1977297439;N:140827", 150, 150, null, null, 1964890519, 1446826412, 1428708103, 1977297439, 140827, "SRX14028689", "SRS11864776", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.93045, null, 0.17846, null, 0.69116, null, 0.48565, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67887, "SRR17868938", "SRX14028688", "SRS11864774", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C2 1", null, "strain:danio rerio AgNPs2|breed:zebrafish7|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 2 1", "AG 2 1", "AG 2 1", "treatment4", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C2-1_1.fq.gz C2-1_2.fq.gz", "fastq fastq", 6795911700.0, 45306078.0, "C2 1 1.fq.gz", "0:150 1:150", "A:1910936263;C:1486390531;G:1471463982;T:1927036309;N:84615", 150, 150, null, null, 1910936263, 1486390531, 1471463982, 1927036309, 84615, "SRX14028688", "SRS11864774", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.93638, null, 0.14847, null, 0.6814, null, 0.46864, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67888, "SRR17868939", "SRX14028687", "SRS11864775", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C1 3", null, "strain:danio rerio AgNPs1|breed:zebrafish6|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 1 3", "AG 1 3", "AG 1 3", "treatment3", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C1-3_1.fq.gz C1-3_2.fq.gz", "fastq fastq", 6788960100.0, 45259734.0, "C1 3 1.fq.gz", "0:150 1:150", "A:1883226902;C:1511814926;G:1492397960;T:1901504019;N:16293", 150, 150, null, null, 1883226902, 1511814926, 1492397960, 1901504019, 16293, "SRX14028687", "SRS11864775", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.94253, null, 0.12673, null, 0.67623, null, 0.49289, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67889, "SRR17868940", "SRX14028686", "SRS11864773", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C1 2", null, "strain:danio rerio AgNPs1|breed:zebrafish5|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 1 2", "AG 1 2", "AG 1 2", "treatment2", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C1-2_1.fq.gz C1-2_2.fq.gz", "fastq fastq", 6781043100.0, 45206954.0, "C1 2 1.fq.gz", "0:150 1:150", "A:1890710017;C:1500221789;G:1482973456;T:1907121929;N:15909", 150, 150, null, null, 1890710017, 1500221789, 1482973456, 1907121929, 15909, "SRX14028686", "SRS11864773", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.93834, null, 0.13288, null, 0.67777, null, 0.49269, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67890, "SRR17868941", "SRX14028685", "SRS11864772", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C1 1", null, "strain:danio rerio AgNPs1|breed:zebrafish4|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 1 1", "AG 1 1", "AG 1 1", "treatment1", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C1-1_1.fq.gz C1-1_2.fq.gz", "fastq fastq", 6760511100.0, 45070074.0, "C1 1 1.fq.gz", "0:150 1:150", "A:1875451292;C:1504527737;G:1489983693;T:1890505493;N:42885", 150, 150, null, null, 1875451292, 1504527737, 1489983693, 1890505493, 42885, "SRX14028685", "SRS11864772", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.94039, null, 0.1298, null, 0.68071, null, 0.49309, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67891, "SRR17868942", "SRX14028684", "SRS11864771", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "WT3", null, "strain:danio rerio con3|breed:zebrafish3|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 0 3", "WT 0 3", "WT 0 3", "control3", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "WT3_1.fq.gz WT3_2.fq.gz", "fastq fastq", 6735369300.0, 44902462.0, "WT3 1.fq.gz", "0:150 1:150", "A:1853105410;C:1513363689;G:1496503080;T:1872187115;N:210006", 150, 150, null, null, 1853105410, 1513363689, 1496503080, 1872187115, 210006, "SRX14028684", "SRS11864771", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.94653, null, 0.11174, null, 0.69116, null, 0.49069, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67892, "SRR17868943", "SRX14028683", "SRS11864768", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C4 3", null, "strain:danio rerio AgNPs4|breed:zebrafish12|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 4 3", "AG 4 3", "AG 4 3", "treatment9", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C4-3_1.fq.gz C4-3_2.fq.gz", "fastq fastq", 7066801800.0, 47112012.0, "C4 3 1.fq.gz", "0:150 1:150", "A:2079705050;C:1456973666;G:1436564156;T:2093467396;N:91532", 150, 150, null, null, 2079705050, 1456973666, 1436564156, 2093467396, 91532, "SRX14028683", "SRS11864768", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.92264, null, 0.21457, null, 0.70236, null, 0.52765, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67893, "SRR17868944", "SRX14028682", "SRS11864769", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "C4 2", null, "strain:danio rerio AgNPs4|breed:zebrafish11|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 4 2", "AG 4 2", "AG 4 2", "treatment8", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "C4-2_1.fq.gz C4-2_2.fq.gz", "fastq fastq", 6813742200.0, 45424948.0, "C4 2 1.fq.gz", "0:150 1:150", "A:1969847243;C:1438590202;G:1418612399;T:1986677730;N:14626", 150, 150, null, null, 1969847243, 1438590202, 1418612399, 1986677730, 14626, "SRX14028682", "SRS11864769", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.92909, null, 0.18109, null, 0.69029, null, 0.50538, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67894, "SRR17868945", "SRX14028681", "SRS11864770", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "WT2", null, "strain:danio rerio con2|breed:zebrafish2|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 0 2", "WT 0 2", "WT 0 2", "control2", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "WT2_1.fq.gz WT2_2.fq.gz", "fastq fastq", 6760866900.0, 45072446.0, "WT2 1.fq.gz", "0:150 1:150", "A:1893259201;C:1485992528;G:1471666738;T:1909709705;N:238728", 150, 150, null, null, 1893259201, 1485992528, 1471666738, 1909709705, 238728, "SRX14028681", "SRS11864770", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.94132, null, 0.13956, null, 0.68596, null, 0.48309, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [67895, "SRR17868946", "SRX14028680", "SRS11864767", "SRP358022", "PRJNA793391", "Effects of acute exposure to nano silver on zebrafish larvae", "PRJNA793391", "Other", "Sliver nanoparticles AgNPs are widely used for industry  agriculture  and medicals  which potentially result in adverse effects for human health and aquatic environment. In this present study  we investigated  the illumine high throughput RNA sequencing revealed the transcriptome profiling of zebrafish larvae post AgNPs treatment for 72 h.", null, null, null, null, "WT1", null, "strain:danio rerio con1|breed:zebrafish1|age:3 day|sex:pooled male and female|tissue:fish|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "DANIO RERIO 0 1", "WT 0 1", "WT 0 1", "control1", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP358022", null, null, "WT1_1.fq.gz WT1_2.fq.gz", "fastq fastq", 7003449300.0, 46689662.0, "WT1 1.fq.gz", "0:150 1:150", "A:1946491315;C:1554368011;G:1539879203;T:1962458586;N:252185", 150, 150, null, null, 1946491315, 1554368011, 1539879203, 1962458586, 252185, "SRX14028680", "SRS11864767", "SRA1350965", "Center for Neuroscience|Shantou university", "Center for Neuroscience", 1, 0.94236, null, 0.12627, null, 0.68369, null, 0.49408, null, 150, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "United States", "2022-02-03", "Larval", "Larval", "Whole Organism", "All anatomical structures"], [74160, "SRR23576624", "SRX19463433", "SRS16856056", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T1B", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis tert no Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T1B", "T1B", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T1B_1.fq.gz T1B_2.fq.gz", "fastq fastq", 12301883400.0, 123018834.0, "T1B 1.fq.gz", "0:100 1:100", "A:3241228917;C:2853095411;G:2904960052;T:3302599020;N:0", 100, 100, null, null, 3241228917, 2853095411, 2904960052, 3302599020, 0, "SRX19463433", "SRS16856056", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95272, null, 0.09396, null, 0.68469, null, 0.54489, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74161, "SRR23576625", "SRX19463432", "SRS16856055", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M9", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M9", "M9", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M9_1.fq.gz M9_2.fq.gz", "fastq fastq", 10791781600.0, 107917816.0, "M9 1.fq.gz", "0:100 1:100", "A:2848108353;C:2487301410;G:2561260439;T:2895111398;N:0", 100, 100, null, null, 2848108353, 2487301410, 2561260439, 2895111398, 0, "SRX19463432", "SRS16856055", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95252, null, 0.05974, null, 0.79184, null, 0.6274, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74162, "SRR23576626", "SRX19463431", "SRS16856054", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M8", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M8", "M8", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M8_1.fq.gz M8_2.fq.gz", "fastq fastq", 10803624400.0, 108036244.0, "M8 1.fq.gz", "0:100 1:100", "A:2826927335;C:2516499907;G:2585204327;T:2874992831;N:0", 100, 100, null, null, 2826927335, 2516499907, 2585204327, 2874992831, 0, "SRX19463431", "SRS16856054", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95494, null, 0.06268, null, 0.79139, null, 0.60873, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74163, "SRR23576627", "SRX19463430", "SRS16856053", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M7", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut WT R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M7", "M7", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M7_1.fq.gz M7_2.fq.gz", "fastq fastq", 10794944600.0, 107949446.0, "M7 1.fq.gz", "0:100 1:100", "A:2822800001;C:2515936087;G:2583221720;T:2872986792;N:0", 100, 100, null, null, 2822800001, 2515936087, 2583221720, 2872986792, 0, "SRX19463430", "SRS16856053", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95392, null, 0.0552, null, 0.78967, null, 0.61766, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74164, "SRR23576628", "SRX19463429", "SRS16856052", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M6", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M6", "M6", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M6_1.fq.gz M6_2.fq.gz", "fastq fastq", 10806717200.0, 108067172.0, "M6 1.fq.gz", "0:100 1:100", "A:2872422644;C:2476696362;G:2537205428;T:2920392766;N:0", 100, 100, null, null, 2872422644, 2476696362, 2537205428, 2920392766, 0, "SRX19463429", "SRS16856052", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95383, null, 0.06563, null, 0.79293, null, 0.63948, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74165, "SRR23576629", "SRX19463428", "SRS16856051", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M5", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M5", "M5", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M5_1.fq.gz M5_2.fq.gz", "fastq fastq", 10553024000.0, 105530240.0, "M5 1.fq.gz", "0:100 1:100", "A:2756587901;C:2467885042;G:2531072385;T:2797478672;N:0", 100, 100, null, null, 2756587901, 2467885042, 2531072385, 2797478672, 0, "SRX19463428", "SRS16856051", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95761, null, 0.05754, null, 0.79435, null, 0.61791, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74166, "SRR23576630", "SRX19463427", "SRS16856048", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M4", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert with Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M4", "M4", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M4_1.fq.gz M4_2.fq.gz", "fastq fastq", 10821109400.0, 108211094.0, "M4 1.fq.gz", "0:100 1:100", "A:2853720356;C:2500021520;G:2567460910;T:2899906614;N:0", 100, 100, null, null, 2853720356, 2500021520, 2567460910, 2899906614, 0, "SRX19463427", "SRS16856048", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95171, null, 0.0636, null, 0.78644, null, 0.61061, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74167, "SRR23576631", "SRX19463426", "SRS16856050", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K9", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow WT R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K9", "K9", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k9_1.fq.gz k9_2.fq.gz", "fastq fastq", 12170484800.0, 121704848.0, "k9 1.fq.gz", "0:100 1:100", "A:3429398396;C:2639165188;G:2664600070;T:3437321146;N:0", 100, 100, null, null, 3429398396, 2639165188, 2664600070, 3437321146, 0, "SRX19463426", "SRS16856050", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.93913, null, 0.13619, null, 0.76623, null, 0.63929, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74168, "SRR23576632", "SRX19463425", "SRS16856047", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K8", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow WT R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K8", "K8", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k8_1.fq.gz k8_2.fq.gz", "fastq fastq", 12160185000.0, 121601850.0, "k8 1.fq.gz", "0:100 1:100", "A:3416677165;C:2642321577;G:2671959016;T:3429227242;N:0", 100, 100, null, null, 3416677165, 2642321577, 2671959016, 3429227242, 0, "SRX19463425", "SRS16856047", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94207, null, 0.13408, null, 0.76211, null, 0.63866, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74169, "SRR23576633", "SRX19463424", "SRS16856049", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K7", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow WT R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K7", "K7", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k7_1.fq.gz k7_2.fq.gz", "fastq fastq", 12148090800.0, 121480908.0, "k7 1.fq.gz", "0:100 1:100", "A:3393484862;C:2656728106;G:2695881495;T:3401996337;N:0", 100, 100, null, null, 3393484862, 2656728106, 2695881495, 3401996337, 0, "SRX19463424", "SRS16856049", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.93783, null, 0.12581, null, 0.76205, null, 0.61561, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74170, "SRR23576634", "SRX19463423", "SRS16856046", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K6", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow tert Cre R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K6", "K6", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k6_1.fq.gz k6_2.fq.gz", "fastq fastq", 12173062600.0, 121730626.0, "k6 1.fq.gz", "0:100 1:100", "A:3357618903;C:2705746086;G:2734807941;T:3374889670;N:0", 100, 100, null, null, 3357618903, 2705746086, 2734807941, 3374889670, 0, "SRX19463423", "SRS16856046", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94651, null, 0.13977, null, 0.76575, null, 0.62959, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74171, "SRR23576635", "SRX19463422", "SRS16856045", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K5", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow tert Cre R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K5", "K5", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k5_1.fq.gz k5_2.fq.gz", "fastq fastq", 12151346800.0, 121513468.0, "k5 1.fq.gz", "0:100 1:100", "A:3323730498;C:2725613099;G:2760112468;T:3341890735;N:0", 100, 100, null, null, 3323730498, 2725613099, 2760112468, 3341890735, 0, "SRX19463422", "SRS16856045", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94297, null, 0.12142, null, 0.75836, null, 0.6001, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74172, "SRR23576636", "SRX19463421", "SRS16856044", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K4", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow tert Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K4", "K4", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k4_1.fq.gz k4_2.fq.gz", "fastq fastq", 12130512600.0, 121305126.0, "k4 1.fq.gz", "0:100 1:100", "A:3347896596;C:2682409134;G:2729255490;T:3370951380;N:0", 100, 100, null, null, 3347896596, 2682409134, 2729255490, 3370951380, 0, "SRX19463421", "SRS16856044", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94729, null, 0.12594, null, 0.75684, null, 0.53755, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74173, "SRR23576637", "SRX19463420", "SRS16856043", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K3", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow no Cre R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K3", "K3", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k3_1.fq.gz k3_2.fq.gz", "fastq fastq", 12414982200.0, 124149822.0, "k3 1.fq.gz", "0:100 1:100", "A:3396256131;C:2779475706;G:2819830912;T:3419419451;N:0", 100, 100, null, null, 3396256131, 2779475706, 2819830912, 3419419451, 0, "SRX19463420", "SRS16856043", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94186, null, 0.13004, null, 0.7613, null, 0.53529, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74174, "SRR23576638", "SRX19463419", "SRS16856040", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "M3", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:gut|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:gut tert without xxx R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male gut", "M3", "M3", "RNA Seq of Danio rerio : adult male gut", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "M3_1.fq.gz M3_2.fq.gz", "fastq fastq", 10811204400.0, 108112044.0, "M3 1.fq.gz", "0:100 1:100", "A:2826338851;C:2514522241;G:2594843889;T:2875499419;N:0", 100, 100, null, null, 2826338851, 2514522241, 2594843889, 2875499419, 0, "SRX19463419", "SRS16856040", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.95049, null, 0.05611, null, 0.79127, null, 0.60997, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gut", "Digestive System"], [74175, "SRR23576639", "SRX19463418", "SRS16856041", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K2", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow no Cre R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K2", "K2", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k2_1.fq.gz k2_2.fq.gz", "fastq fastq", 12163413800.0, 121634138.0, "k2 1.fq.gz", "0:100 1:100", "A:3349566787;C:2697789330;G:2746344614;T:3369713069;N:0", 100, 100, null, null, 3349566787, 2697789330, 2746344614, 3369713069, 0, "SRX19463418", "SRS16856041", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.93698, null, 0.12494, null, 0.73933, null, 0.59199, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74176, "SRR23576640", "SRX19463417", "SRS16856042", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "K1", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:kidney marrow|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:kidneymarrow no Cre R1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male kidney marrow", "K1", "K1", "RNA Seq of Danio rerio : adult male kidney marrow", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "k1_1.fq.gz k1_2.fq.gz", "fastq fastq", 12163054400.0, 121630544.0, "k1 1.fq.gz", "0:100 1:100", "A:3337026687;C:2722574700;G:2757511786;T:3345941227;N:0", 100, 100, null, null, 3337026687, 2722574700, 2757511786, 3345941227, 0, "SRX19463417", "SRS16856042", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94273, null, 0.11801, null, 0.75258, null, 0.57192, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Kidney", "Renal System"], [74177, "SRR23576641", "SRX19463416", "SRS16856039", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T9", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T9", "T9", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T9_1.fq.gz T9_2.fq.gz", "fastq fastq", 12386772800.0, 123867728.0, "T9 1.fq.gz", "0:100 1:100", "A:3400599530;C:2772066139;G:2813890387;T:3400216744;N:0", 100, 100, null, null, 3400599530, 2772066139, 2813890387, 3400216744, 0, "SRX19463416", "SRS16856039", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.93775, null, 0.12024, null, 0.63838, null, 0.49765, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74178, "SRR23576642", "SRX19463415", "SRS16856037", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. Our work demonstrates that delaying telomere shortening in the gut is sufficient to systemically counteract aging in zebrafish.", null, null, null, null, "T8", null, "strain:AB|age:9 month|dev stage:adulte|sex:male|tissue:testis|biomaterial provider:EL MAI Mounir|birth date:2019/11/20|birth location:Nice France|treatment:testis WT R2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of Danio rerio : adult male testis", "T8", "T8", "RNA Seq of Danio rerio : adult male testis", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "BGISEQ", "BGISEQ-500", null, "SRP423783", null, null, "T8_1.fq.gz T8_2.fq.gz", "fastq fastq", 12176715600.0, 121767156.0, "T8 1.fq.gz", "0:100 1:100", "A:3287270041;C:2775700062;G:2808469679;T:3305275818;N:0", 100, 100, null, null, 3287270041, 2775700062, 2808469679, 3305275818, 0, "SRX19463415", "SRS16856037", "SRA1593824", "Sun Yat-sen University Cancer Center|State Key Laboratory of Oncology in South China", "Sun Yat-sen University Cancer Center Miguel Godinho Ferreira", 1, 0.94261, null, 0.12625, null, 0.63838, null, 0.49901, null, 100, null, "B", null, "usable mapping rate", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-02-21", "Adult", "Adult", "Gonad", "Reproductive System"], [74179, "SRR23576643", "SRX19463414", "SRS16856038", "SRP423783", "PRJNA937311", "Telomere elongation in the gut extends systemic healthspan of zebrafish", "PRJNA937311", "Other", "Telomere shortening is a hallmark of aging and is counteracted by telomerase. zebrafish gut is one of the organs with the fastest rate of telomere decline. However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. 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However  whether telomere dependent aging of an individual organ  the gut  causes systemic aging remains unknown. Here  we show that preventing telomere shortening in the gut through tissue specific telomerase expression rescues premature aging of tert / . Conclusively  we show that gut specific telomerase expression extends lifespan of tert /  by 40 %  while ameliorating natural aging. 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