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We analyzed age associated gene expression pattern in zebrafish and compared with similar public transcriptome data of rat Yu et al.  2014.", null, null, null, "liver sample from 16 mpf zebrafish replicate1", "SAMD00152474", null, "sample name:l16 1|age:16 month|biological replicate:1|tissue:liver", null, null, null, null, null, null, null, null, "Illumina HiSeq 2000 paired end sequencing of SAMD00152474", "DRX153145", "1", "1", "Illumina TruSeq Stranded mRNA HT Kit", null, "RNA-Seq", "TRANSCRIPTOMIC", "cDNA", "PAIRED", "ILLUMINA", "Illumina HiSeq 2000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP004696", "Illumina HiSeq 2000 paired end sequencing of SAMD00152474", null, null, null, 1153415600.0, 5767078.0, "DRR162526", "0:100 1:100", "A:331352139;C:244998423;G:248301842;T:328704463;N:58733", 100, 100, null, null, 331352139, 244998423, 248301842, 328704463, 58733, "DRX153145", "DRS083206", "DRA007711", "UT-AQUA|Laboratory of Aquatic Molecular Biology and Biotechnology", "Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo", 2, 0.95303, 0.95385, 0.03203, 0.03206, 0.86592, 0.86734, 0.23054, 0.23207, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "cdna_unspecified", "trueseq", "bulk", "unknown", "unknown", null, "Japan", "2018-12-24", "Adult", "Adult", "Liver", "Liver and Biliary System"], [216, "DRR162525", "DRX153144", "DRS083205", "DRP004696", "PRJDB7713", "Age associated transcriptome analysis in 5 tissues of zebrafish", "DRP004696", "Transcriptome Analysis", "We performed transcriptome analysis for brain  gill  heart  liver and muscle from 2 month   7 month   16 month  and 39 mpf zebrafish. 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We analyzed age associated gene expression pattern in zebrafish and compared with similar public transcriptome data of rat Yu et al.  2014.", null, null, null, "liver sample from 7 mpf zebrafish replicate4", "SAMD00152472", null, "sample name:l07 4|age:7 month|biological replicate:4|tissue:liver", null, null, null, null, null, null, null, null, "Illumina HiSeq 2000 paired end sequencing of SAMD00152472", "DRX153143", "1", "1", "Illumina TruSeq Stranded mRNA HT Kit", null, "RNA-Seq", "TRANSCRIPTOMIC", "cDNA", "PAIRED", "ILLUMINA", "Illumina HiSeq 2000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP004696", "Illumina HiSeq 2000 paired end sequencing of SAMD00152472", null, null, null, 1483455800.0, 7417279.0, "DRR162524", "0:100 1:100", "A:436293893;C:304891230;G:308137580;T:434055810;N:77287", 100, 100, null, null, 436293893, 304891230, 308137580, 434055810, 77287, "DRX153143", "DRS083204", "DRA007711", "UT-AQUA|Laboratory of Aquatic Molecular Biology and Biotechnology", "Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo", 2, 0.91896, 0.90192, 0.0717, 0.07014, 0.81085, 0.8132, 0.58351, 0.59366, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "cdna_unspecified", "trueseq", "bulk", "unknown", "unknown", null, "Japan", "2018-12-24", "Adult", "Adult", "Liver", "Liver and Biliary System"], [218, "DRR162523", "DRX153142", "DRS083203", "DRP004696", "PRJDB7713", "Age associated transcriptome analysis in 5 tissues of zebrafish", "DRP004696", "Transcriptome Analysis", "We performed transcriptome analysis for brain  gill  heart  liver and muscle from 2 month   7 month   16 month  and 39 mpf zebrafish. We analyzed age associated gene expression pattern in zebrafish and compared with similar public transcriptome data of rat Yu et al.  2014.", null, null, null, "liver sample from 7 mpf zebrafish replicate3", "SAMD00152471", null, "sample name:l07 3|age:7 month|biological replicate:3|tissue:liver", null, null, null, null, null, null, null, null, "Illumina HiSeq 2000 paired end sequencing of SAMD00152471", "DRX153142", "1", "1", "Illumina TruSeq Stranded mRNA HT Kit", null, "RNA-Seq", "TRANSCRIPTOMIC", "cDNA", "PAIRED", "ILLUMINA", "Illumina HiSeq 2000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP004696", "Illumina HiSeq 2000 paired end sequencing of SAMD00152471", null, null, null, 1864489400.0, 9322447.0, "DRR162523", "0:100 1:100", "A:502417821;C:427210740;G:431014519;T:503749673;N:96647", 100, 100, null, null, 502417821, 427210740, 431014519, 503749673, 96647, "DRX153142", "DRS083203", "DRA007711", "UT-AQUA|Laboratory of Aquatic Molecular Biology and Biotechnology", "Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo", 2, 0.95976, 0.96143, 0.04395, 0.04468, 0.79448, 0.79782, 0.263, 0.26714, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "cdna_unspecified", "trueseq", "bulk", "unknown", "unknown", null, "Japan", "2018-12-24", "Adult", "Adult", "Liver", "Liver and Biliary System"], [219, "DRR162522", "DRX153141", "DRS083202", "DRP004696", "PRJDB7713", "Age associated transcriptome analysis in 5 tissues of zebrafish", "DRP004696", "Transcriptome Analysis", "We performed transcriptome analysis for brain  gill  heart  liver and muscle from 2 month   7 month   16 month  and 39 mpf zebrafish. We analyzed age associated gene expression pattern in zebrafish and compared with similar public transcriptome data of rat Yu et al.  2014.", null, null, null, "liver sample from 7 mpf zebrafish replicate2", "SAMD00152470", null, "sample name:l07 2|age:7 month|biological replicate:2|tissue:liver", null, null, null, null, null, null, null, null, "Illumina HiSeq 2000 paired end sequencing of SAMD00152470", "DRX153141", "1", "1", "Illumina TruSeq Stranded mRNA HT Kit", null, "RNA-Seq", "TRANSCRIPTOMIC", "cDNA", "PAIRED", "ILLUMINA", "Illumina HiSeq 2000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP004696", "Illumina HiSeq 2000 paired end sequencing of SAMD00152470", null, null, null, 2033108200.0, 10165541.0, "DRR162522", "0:100 1:100", "A:551635703;C:463271027;G:463695854;T:554401182;N:104434", 100, 100, null, null, 551635703, 463271027, 463695854, 554401182, 104434, "DRX153141", "DRS083202", "DRA007711", "UT-AQUA|Laboratory of Aquatic Molecular Biology and Biotechnology", "Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo", 2, 0.94795, 0.94217, 0.05903, 0.0589, 0.79131, 0.79462, 0.54196, 0.5496, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "cdna_unspecified", "trueseq", "bulk", "unknown", "unknown", null, "Japan", "2018-12-24", "Adult", "Adult", "Liver", "Liver and Biliary System"], [220, "DRR162521", "DRX153140", "DRS083201", "DRP004696", "PRJDB7713", "Age associated transcriptome analysis in 5 tissues of zebrafish", "DRP004696", "Transcriptome Analysis", "We performed transcriptome analysis for brain  gill  heart  liver and muscle from 2 month   7 month   16 month  and 39 mpf zebrafish. We analyzed age associated gene expression pattern in zebrafish and compared with similar public transcriptome data of rat Yu et al.  2014.", null, null, null, "liver sample from 7 mpf zebrafish replicate1", "SAMD00152469", null, "sample name:l07 1|age:7 month|biological replicate:1|tissue:liver", null, null, null, null, null, null, null, null, "Illumina HiSeq 2000 paired end sequencing of SAMD00152469", "DRX153140", "1", "1", "Illumina TruSeq Stranded mRNA HT Kit", null, "RNA-Seq", "TRANSCRIPTOMIC", "cDNA", "PAIRED", "ILLUMINA", "Illumina HiSeq 2000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP004696", "Illumina HiSeq 2000 paired end sequencing of SAMD00152469", null, null, null, 1468954400.0, 7344772.0, "DRR162521", "0:100 1:100", "A:395399684;C:336608951;G:340607200;T:396263402;N:75163", 100, 100, null, null, 395399684, 336608951, 340607200, 396263402, 75163, "DRX153140", "DRS083201", "DRA007711", "UT-AQUA|Laboratory of Aquatic Molecular Biology and Biotechnology", "Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo", 2, 0.95562, 0.95778, 0.02931, 0.02966, 0.86667, 0.8686, 0.15375, 0.16038, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "cdna_unspecified", "trueseq", "bulk", "unknown", "unknown", null, "Japan", "2018-12-24", "Adult", "Adult", "Liver", "Liver and Biliary System"], [280, "DRR161311", "DRX151936", "DRS095335", "DRP005084", "PRJDB7735", "Gene expression profile in adult zebrafish liver", "DRP005084", "Transcriptome Analysis", "Increasing use of zebrafish in toxicological researches requires knowledge on gene expression profile in liver that play a major role in xenobiotic metabolism. Our research provide a basal gene expression profile in adult zebrafish liver.", null, null, null, "Transcriptome of female Danio rerio liver", "SAMD00153247", null, "sample name:transcriptome zebrafish female|sex:female|strain:RIKEN WT|tissue:liver", null, null, null, null, null, null, null, null, "NextSeq 500 paired end sequencing of SAMD00153247", "DRX151936", "f", "1", "1", null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "NextSeq 500", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>152</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>77</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP005084", "NextSeq 500 paired end sequencing of SAMD00153247", null, null, null, 2338564937.0, 15498367.0, "DRR161311", "0:75.45 1:75.44", "A:613899755;C:541756858;G:548366901;T:633083422;N:1458001", 75, 75, null, null, 613899755, 541756858, 548366901, 633083422, 1458001, "DRX151936", "DRS095335", "DRA007652", "OBICHIKU|Laboratory of Toxicology, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine", "Laboratory of Toxicology, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine", 2, 0.95814, 0.96362, 0.05394, 0.04517, 0.77932, 0.7834, 0.37385, 0.37264, 76, 76, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2019-05-20", "Undetermined", "Adult", "Liver", "Liver and Biliary System"], [281, "DRR161310", "DRX151935", "DRS095334", "DRP005084", "PRJDB7735", "Gene expression profile in adult zebrafish liver", "DRP005084", "Transcriptome Analysis", "Increasing use of zebrafish in toxicological researches requires knowledge on gene expression profile in liver that play a major role in xenobiotic metabolism. Our research provide a basal gene expression profile in adult zebrafish liver.", null, null, null, "Transcriptome of male Danio rerio liver", "SAMD00153246", null, "sample name:transcriptome zebrafish male|sex:male|strain:RIKEN WT|tissue:liver", null, null, null, null, null, null, null, null, "NextSeq 500 paired end sequencing of SAMD00153246", "DRX151935", "m", "1", "1", null, "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "NextSeq 500", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>152</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>77</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "DRP005084", "NextSeq 500 paired end sequencing of SAMD00153246", null, null, null, 2506978527.0, 16611154.0, "DRR161310", "0:75.48 1:75.44", "A:672321355;C:568289588;G:569411670;T:695545626;N:1410288", 75, 75, null, null, 672321355, 568289588, 569411670, 695545626, 1410288, "DRX151935", "DRS095334", "DRA007652", "OBICHIKU|Laboratory of Toxicology, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine", "Laboratory of Toxicology, Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine", 2, 0.94746, 0.95115, 0.07899, 0.06363, 0.80837, 0.8115, 0.52008, 0.58743, 76, 76, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Japan", "2019-05-20", "Undetermined", "Adult", "Liver", "Liver and Biliary System"], [9355, "ERR2983453", "ERX2986069", "ERS2955657", "ERP112513", "PRJEB30097", "RNA Seq of Danionine species", "E-MTAB-7476", "Transcriptome Analysis", "Tissues specific transcriptomes of Danio rerio  Danio albolineatus and Danio aesculapii Brain  Liver and Gonads.", "ENA FIRST PUBLIC:2018 12 05|ENA LAST UPDATE:2018 12 05", null, "Protocols: Organs were sampled and snap frozen in liquid nitrogen RNA was extracted using Trizol and standard silica membrane protocol Library was constructed using magnetic beads dT to enrich mRNA. post fragmentation the cDNA was synthesized using the mRNA fragments as templates with random hexamer primers.", "R3wL", "SAMEA5147912", "University of Hamburg, Institute of Zoology, Molecular Animal Physiology", "ENA FIRST PUBLIC:2018 12 05T17:02:27Z|ENA LAST UPDATE:2018 12 05T10:01:48Z|External Id:SAMEA5147912|INSDC center name:University of Hamburg  Institute of Zoology  Molecular Animal Physiology|INSDC first public:2018 12 05T17:02:27Z|INSDC last update:2018 12 05T10:01:48Z|INSDC status:public|Submitter Id:E MTAB 7476:R3wL|age:3|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|genotype:wild type genotype|individual:3|organism part:liver|sample name:E MTAB 7476:R3wL|scientific name:Danio rerio|sex:female|strain:tu", null, null, null, null, null, null, null, null, "Illumina HiSeq 4000 paired end sequencing; RNA Seq of Danio9 species", "E MTAB 7476:R3wL p", "R3wL p", "RNA Seq of Danionine species", "Organs were sampled and snap frozen in liquid nitrogen   RNA was extracted using Trizol and standard silica membrane protocol  Library was constructed using magnetic beads dT to enrich mRNA. post fragmentation the cDNA was synthesized using the mRNA fragments as templates with random hexamer primers.", "Experimental Factor: organism:Danio rerio|Experimental Factor: organism part:liver", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 4000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_LABEL>F</READ_LABEL><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_LABEL>R</READ_LABEL><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "ERP112513", "Illumina HiSeq 4000 paired end sequencing; RNA Seq of Danionine species", "ENA FIRST PUBLIC:2018 12 05|ENA LAST UPDATE:2018 12 05", "FCHNW2WBBXX_L6_HKZEBodsEAADRAAPEI-207_1.fq.gz FCHNW2WBBXX_L6_HKZEBodsEAADRAAPEI-207_2.fq.gz", "fastq fastq", 3900536400.0, 19502682.0, "E MTAB 7476:FCHNW2WBBXX L6 HKZEBodsEAADRAAPEI 207 ", "0:100 1:100", "A:1018803847;C:926996866;G:925339368;T:1028563032;N:833287", 100, 100, null, null, 1018803847, 926996866, 925339368, 1028563032, 833287, "ERX2986069", "ERS2955657", "ERA1674470", "University of Hamburg, Institute of Zoology, Molecular Animal Physiology|European Nucleotide Archive", "University of Hamburg, Institute of Zoology, Molecular Animal Physiology|European Nucleotide Archive", 2, 0.97722, 0.97727, 0.02792, 0.02783, 0.84476, 0.84664, 0.17004, 0.16966, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Germany", "2018-12-05", "Adult", "Adult", "Liver", "Liver and Biliary System"], [9358, "ERR2983450", "ERX2986066", "ERS2955654", "ERP112513", "PRJEB30097", "RNA Seq of Danionine species", "E-MTAB-7476", "Transcriptome Analysis", "Tissues specific transcriptomes of Danio rerio  Danio albolineatus and Danio aesculapii Brain  Liver and Gonads.", "ENA FIRST PUBLIC:2018 12 05|ENA LAST UPDATE:2018 12 05", null, "Protocols: Organs were sampled and snap frozen in liquid nitrogen RNA was extracted using Trizol and standard silica membrane protocol Library was constructed using magnetic beads dT to enrich mRNA. post fragmentation the cDNA was synthesized using the mRNA fragments as templates with random hexamer primers.", "R1wL", "SAMEA5147909", "University of Hamburg, Institute of Zoology, Molecular Animal Physiology", "ENA FIRST PUBLIC:2018 12 05T17:02:27Z|ENA LAST UPDATE:2018 12 05T10:01:48Z|External Id:SAMEA5147909|INSDC center name:University of Hamburg  Institute of Zoology  Molecular Animal Physiology|INSDC first public:2018 12 05T17:02:27Z|INSDC last update:2018 12 05T10:01:48Z|INSDC status:public|Submitter Id:E MTAB 7476:R1wL|age:3|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|genotype:wild type genotype|individual:1|organism part:liver|sample name:E MTAB 7476:R1wL|scientific name:Danio rerio|sex:female|strain:tu", null, null, null, null, null, null, null, null, "Illumina HiSeq 4000 paired end sequencing; RNA Seq of Danio9 species", "E MTAB 7476:R1wL p", "R1wL p", "RNA Seq of Danionine species", "Organs were sampled and snap frozen in liquid nitrogen   RNA was extracted using Trizol and standard silica membrane protocol  Library was constructed using magnetic beads dT to enrich mRNA. post fragmentation the cDNA was synthesized using the mRNA fragments as templates with random hexamer primers.", "Experimental Factor: organism:Danio rerio|Experimental Factor: organism part:liver", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 4000", "<SPOT_DESCRIPTOR><SPOT_DECODE_SPEC><SPOT_LENGTH>200</SPOT_LENGTH><READ_SPEC><READ_INDEX>0</READ_INDEX><READ_LABEL>F</READ_LABEL><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Forward</READ_TYPE><BASE_COORD>1</BASE_COORD></READ_SPEC><READ_SPEC><READ_INDEX>1</READ_INDEX><READ_LABEL>R</READ_LABEL><READ_CLASS>Application Read</READ_CLASS><READ_TYPE>Reverse</READ_TYPE><BASE_COORD>101</BASE_COORD></READ_SPEC></SPOT_DECODE_SPEC></SPOT_DESCRIPTOR>", "ERP112513", "Illumina HiSeq 4000 paired end sequencing; RNA Seq of Danionine species", "ENA FIRST PUBLIC:2018 12 05|ENA LAST UPDATE:2018 12 05", "FCHNW2WBBXX_L6_HKZEBodsEAACRAAPEI-206_1.fq.gz FCHNW2WBBXX_L6_HKZEBodsEAACRAAPEI-206_2.fq.gz", "fastq fastq", 3542921400.0, 17714607.0, "E MTAB 7476:FCHNW2WBBXX L6 HKZEBodsEAACRAAPEI 206 ", "0:100 1:100", "A:927287253;C:840581371;G:838113814;T:936174847;N:764115", 100, 100, null, null, 927287253, 840581371, 838113814, 936174847, 764115, "ERX2986066", "ERS2955654", "ERA1674470", "University of Hamburg, Institute of Zoology, Molecular Animal Physiology|European Nucleotide Archive", "University of Hamburg, Institute of Zoology, Molecular Animal Physiology|European Nucleotide Archive", 2, 0.9748, 0.9739, 0.02815, 0.02746, 0.84248, 0.84439, 0.17403, 0.17668, 100, 100, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Germany", "2018-12-05", "Adult", "Adult", "Liver", "Liver and Biliary System"], [9833, "ERR4029234", "ERX4030550", "ERS4513988", "ERP121186", "PRJEB37848", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E-MTAB-8959", "Transcriptome Analysis", "The aim of this sequencing experiment was to make available tissue expression panels for selected fish species for comparative expression studies between the species. Tissue samples were collected for zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss. Tissue types included liver  skin  muscle  heart  gut  gill  eye  brain for all three species  with additionally pyloric caeca  kidney  head kidney  and spleen for rainbow trout. Only liver samples were taken in replicate of four or three for rainbow trout. All fish were raised under standard rearing conditions for the species. Total RNA was extracted from the tissue samples and paired end sequencing of sample libraries was completed on an Illumina HiSeq 2500 with 125 bp reads. Processed count tables per species as raw counts  FPKM  or TPM  were generated from read alignment to the Ensembl genomes of the respective species using STAR and gene level counting using RSEM and Ensembl gene annotation.", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", null, "Protocols: Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "ZF L 1", "SAMEA6786308", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences", "ENA FIRST PUBLIC:2020 04 30T04:03:51Z|ENA LAST UPDATE:2020 04 16T14:24:16Z|External Id:SAMEA6786308|INSDC center name:CIGENE  Faculty of Biosciences  The Norwegian University of Life Sciences|INSDC first public:2020 04 30T04:03:51Z|INSDC last update:2020 04 16T14:24:16Z|INSDC status:public|Submitter Id:E MTAB 8959:ZF L 1|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|organism part:liver|sample name:E MTAB 8959:ZF L 1|scientific name:Danio rerio|sex:male", null, null, null, null, null, null, null, null, "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E MTAB 8959:ZF L 1 p", "ZF L 1 p", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "Experimental Factor: organism part:liver|Experimental Factor: organism:Danio rerio", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 2500", null, "ERP121186", "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", "ZF-L-1_ATTACTCG-TATAGCCT_R1_001.fastq.gz ZF-L-1_ATTACTCG-TATAGCCT_R2_001.fastq.gz", "fastq fastq", 6531942312.0, 25920406.0, "E MTAB 8959:ZF L 1 ATTACTCG TATAGCCT R", "0:126 1:126", "A:1742074981;C:1508007466;G:1507640617;T:1773534883;N:684365", 126, 126, null, null, 1742074981, 1508007466, 1507640617, 1773534883, 684365, "ERX4030550", "ERS4513988", "ERA2508028", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", 2, 0.95365, 0.94664, 0.057, 0.05639, 0.78334, 0.78451, 0.57079, 0.57336, 126, 126, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "trueseq", "bulk", "unknown", "unknown", null, "Norway", "2020-04-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [9836, "ERR4029231", "ERX4030547", "ERS4513985", "ERP121186", "PRJEB37848", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E-MTAB-8959", "Transcriptome Analysis", "The aim of this sequencing experiment was to make available tissue expression panels for selected fish species for comparative expression studies between the species. Tissue samples were collected for zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss. Tissue types included liver  skin  muscle  heart  gut  gill  eye  brain for all three species  with additionally pyloric caeca  kidney  head kidney  and spleen for rainbow trout. Only liver samples were taken in replicate of four or three for rainbow trout. All fish were raised under standard rearing conditions for the species. Total RNA was extracted from the tissue samples and paired end sequencing of sample libraries was completed on an Illumina HiSeq 2500 with 125 bp reads. Processed count tables per species as raw counts  FPKM  or TPM  were generated from read alignment to the Ensembl genomes of the respective species using STAR and gene level counting using RSEM and Ensembl gene annotation.", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", null, "Protocols: Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "ZF G 1", "SAMEA6786305", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences", "ENA FIRST PUBLIC:2020 04 30T04:03:51Z|ENA LAST UPDATE:2020 04 16T14:24:16Z|External Id:SAMEA6786305|INSDC center name:CIGENE  Faculty of Biosciences  The Norwegian University of Life Sciences|INSDC first public:2020 04 30T04:03:51Z|INSDC last update:2020 04 16T14:24:16Z|INSDC status:public|Submitter Id:E MTAB 8959:ZF G 1|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|organism part:gut|sample name:E MTAB 8959:ZF G 1|scientific name:Danio rerio|sex:male", null, null, null, null, null, null, null, null, "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E MTAB 8959:ZF G 1 p", "ZF G 1 p", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "Experimental Factor: organism part:gut|Experimental Factor: organism:Danio rerio", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 2500", null, "ERP121186", "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", "ZF-G-1_ATTACTCG-GTACTGAC_R1_001.fastq.gz ZF-G-1_ATTACTCG-GTACTGAC_R2_001.fastq.gz", "fastq fastq", 4704841764.0, 18670007.0, "E MTAB 8959:ZF G 1 ATTACTCG GTACTGAC R", "0:126 1:126", "A:1201875466;C:1104244497;G:1149324323;T:1248857914;N:539564", 126, 126, null, null, 1201875466, 1104244497, 1149324323, 1248857914, 539564, "ERX4030547", "ERS4513985", "ERA2508028", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", 2, 0.95324, 0.95304, 0.0643, 0.06517, 0.67588, 0.68239, 0.55928, 0.55357, 126, 126, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "trueseq", "bulk", "unknown", "unknown", null, "Norway", "2020-04-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [9839, "ERR4029220", "ERX4030536", "ERS4513974", "ERP121186", "PRJEB37848", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E-MTAB-8959", "Transcriptome Analysis", "The aim of this sequencing experiment was to make available tissue expression panels for selected fish species for comparative expression studies between the species. Tissue samples were collected for zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss. Tissue types included liver  skin  muscle  heart  gut  gill  eye  brain for all three species  with additionally pyloric caeca  kidney  head kidney  and spleen for rainbow trout. Only liver samples were taken in replicate of four or three for rainbow trout. All fish were raised under standard rearing conditions for the species. Total RNA was extracted from the tissue samples and paired end sequencing of sample libraries was completed on an Illumina HiSeq 2500 with 125 bp reads. Processed count tables per species as raw counts  FPKM  or TPM  were generated from read alignment to the Ensembl genomes of the respective species using STAR and gene level counting using RSEM and Ensembl gene annotation.", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", null, "Protocols: Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "ZF L 3", "SAMEA6786294", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences", "ENA FIRST PUBLIC:2020 04 30T04:03:51Z|ENA LAST UPDATE:2020 04 16T14:24:16Z|External Id:SAMEA6786294|INSDC center name:CIGENE  Faculty of Biosciences  The Norwegian University of Life Sciences|INSDC first public:2020 04 30T04:03:51Z|INSDC last update:2020 04 16T14:24:16Z|INSDC status:public|Submitter Id:E MTAB 8959:ZF L 3|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|organism part:liver|sample name:E MTAB 8959:ZF L 3|scientific name:Danio rerio|sex:female", null, null, null, null, null, null, null, null, "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E MTAB 8959:ZF L 3 p", "ZF L 3 p", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "Experimental Factor: organism part:liver|Experimental Factor: organism:Danio rerio", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 2500", null, "ERP121186", "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", "ZF-L-3_ATTACTCG-CCTATCCT_R1_001.fastq.gz ZF-L-3_ATTACTCG-CCTATCCT_R2_001.fastq.gz", "fastq fastq", 4015386648.0, 15934074.0, "E MTAB 8959:ZF L 3 ATTACTCG CCTATCCT R", "0:126 1:126", "A:1056740845;C:942055204;G:937642096;T:1078450107;N:498396", 126, 126, null, null, 1056740845, 942055204, 937642096, 1078450107, 498396, "ERX4030536", "ERS4513974", "ERA2508028", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", 2, 0.96926, 0.97065, 0.03757, 0.03737, 0.81592, 0.81742, 0.30093, 0.3039, 126, 126, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "trueseq", "bulk", "unknown", "unknown", null, "Norway", "2020-04-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [9840, "ERR4029216", "ERX4030532", "ERS4513970", "ERP121186", "PRJEB37848", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E-MTAB-8959", "Transcriptome Analysis", "The aim of this sequencing experiment was to make available tissue expression panels for selected fish species for comparative expression studies between the species. Tissue samples were collected for zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss. Tissue types included liver  skin  muscle  heart  gut  gill  eye  brain for all three species  with additionally pyloric caeca  kidney  head kidney  and spleen for rainbow trout. Only liver samples were taken in replicate of four or three for rainbow trout. All fish were raised under standard rearing conditions for the species. Total RNA was extracted from the tissue samples and paired end sequencing of sample libraries was completed on an Illumina HiSeq 2500 with 125 bp reads. Processed count tables per species as raw counts  FPKM  or TPM  were generated from read alignment to the Ensembl genomes of the respective species using STAR and gene level counting using RSEM and Ensembl gene annotation.", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", null, "Protocols: Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "ZF L 6", "SAMEA6786290", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences", "ENA FIRST PUBLIC:2020 04 30T04:03:51Z|ENA LAST UPDATE:2020 04 16T14:24:15Z|External Id:SAMEA6786290|INSDC center name:CIGENE  Faculty of Biosciences  The Norwegian University of Life Sciences|INSDC first public:2020 04 30T04:03:51Z|INSDC last update:2020 04 16T14:24:15Z|INSDC status:public|Submitter Id:E MTAB 8959:ZF L 6|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|organism part:liver|sample name:E MTAB 8959:ZF L 6|scientific name:Danio rerio|sex:not available", null, null, null, null, null, null, null, null, "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E MTAB 8959:ZF L 6 p", "ZF L 6 p", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "Experimental Factor: organism part:liver|Experimental Factor: organism:Danio rerio", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 2500", null, "ERP121186", "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", "ZF-L-6_ATTACTCG-GGCTCTGA_R1_001.fastq.gz ZF-L-6_ATTACTCG-GGCTCTGA_R2_001.fastq.gz", "fastq fastq", 4678483320.0, 18565410.0, "E MTAB 8959:ZF L 6 ATTACTCG GGCTCTGA R", "0:126 1:126", "A:1222934876;C:1105593331;G:1115480454;T:1234057377;N:417282", 126, 126, null, null, 1222934876, 1105593331, 1115480454, 1234057377, 417282, "ERX4030532", "ERS4513970", "ERA2508028", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", 2, 0.96734, 0.97048, 0.03122, 0.02865, 0.84293, 0.84482, 0.2604, 0.27423, 126, 126, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "trueseq", "bulk", "unknown", "unknown", null, "Norway", "2020-04-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [9841, "ERR4029215", "ERX4030531", "ERS4513969", "ERP121186", "PRJEB37848", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E-MTAB-8959", "Transcriptome Analysis", "The aim of this sequencing experiment was to make available tissue expression panels for selected fish species for comparative expression studies between the species. Tissue samples were collected for zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss. Tissue types included liver  skin  muscle  heart  gut  gill  eye  brain for all three species  with additionally pyloric caeca  kidney  head kidney  and spleen for rainbow trout. Only liver samples were taken in replicate of four or three for rainbow trout. All fish were raised under standard rearing conditions for the species. Total RNA was extracted from the tissue samples and paired end sequencing of sample libraries was completed on an Illumina HiSeq 2500 with 125 bp reads. Processed count tables per species as raw counts  FPKM  or TPM  were generated from read alignment to the Ensembl genomes of the respective species using STAR and gene level counting using RSEM and Ensembl gene annotation.", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 04 16", null, "Protocols: Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "ZF L 5", "SAMEA6786289", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences", "ENA FIRST PUBLIC:2020 04 30T04:03:51Z|ENA LAST UPDATE:2020 04 16T14:24:15Z|External Id:SAMEA6786289|INSDC center name:CIGENE  Faculty of Biosciences  The Norwegian University of Life Sciences|INSDC first public:2020 04 30T04:03:51Z|INSDC last update:2020 04 16T14:24:15Z|INSDC status:public|Submitter Id:E MTAB 8959:ZF L 5|broker name:ArrayExpress|common name:zebrafish|developmental stage:adult|organism part:liver|sample name:E MTAB 8959:ZF L 5|scientific name:Danio rerio|sex:not available", null, null, null, null, null, null, null, null, "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "E MTAB 8959:ZF L 5 p", "ZF L 5 p", "RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "Tissue samples of multiple types were collected from adult individuals of zebrafish  medaka  and rainbow trout. Liver tissue samples were taken in replicates of four  or three in the case of rainbow trout. All fish were raised in fresh water under standard rearing conditions in aquaculture facilities rainbow trout: Aquagen broodstock  tanks at NIVA solbergstranda  or animal laboratory facilities zebrafish  medaka: VetBio  adamstuen. Total RNA was extracted from the tissue samples using the RNeasy Plus Universal Kit QIAGEN. Quality was determined on a 2100 Bioanalyzer using the RNA 6000 Nano Kit Agilent. Concentration was determined using a Nanodrop 8000 spectrophotometer Thermo Scientific. cDNA libraries were prepared using the TruSeq Stranded mRNA HT Sample Prep Kit Illumina. Library mean length was determined by running on a 2100 Bioanalyzer using the DNA 1000 Kit Agilent and library concentration was determined with the Qbit BR Kit Thermo Scientific.", "Experimental Factor: organism part:liver|Experimental Factor: organism:Danio rerio", "RNA-Seq", "TRANSCRIPTOMIC", "Oligo-dT", "PAIRED", "ILLUMINA", "Illumina HiSeq 2500", null, "ERP121186", "Illumina HiSeq 2500 paired end sequencing; RNA seq of tissue panel samples from zebrafish Danio rerio  medaka Oryzias latipes  and rainbow trout Oncorhynchus mykiss", "ENA FIRST PUBLIC:2020 04 30|ENA LAST UPDATE:2020 06 19", "ZF-L-5_ATTACTCG-ATAGAGGC_R1_001.fastq.gz ZF-L-5_ATTACTCG-ATAGAGGC_R2_001.fastq.gz", "fastq fastq", 4735140228.0, 18790239.0, "E MTAB 8959:ZF L 5 ATTACTCG ATAGAGGC R", "0:126 1:126", "A:1234730507;C:1119686445;G:1126456409;T:1253805646;N:461221", 126, 126, null, null, 1234730507, 1119686445, 1126456409, 1253805646, 461221, "ERX4030531", "ERS4513969", "ERA2508028", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", "CIGENE, Faculty of Biosciences, The Norwegian University of Life Sciences|European Nucleotide Archive", 2, 0.96297, 0.96851, 0.02196, 0.02241, 0.86598, 0.8687, 0.25119, 0.2498, 126, 126, "B", "B", "biological fallback assumption", "illumina", "hiseq_era", "unknown", "poly_a", "trueseq", "bulk", "unknown", "unknown", null, "Norway", "2020-04-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26525, "SRR26078869", "SRX21793734", "SRS18895475", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "liver specific overexpression of Igfbp7 3", "LOE replicate 3", null, "strain:transgenic strain|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:LOE replicate=biological replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "liver specific overexpression of Igfbp7 3", "LOE3", "LOE3", "liver specific overexpression of Igfbp7 3", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "LOE3_1.fq.gz LOE3_2.fq.gz", "fastq fastq", 7457209500.0, 24857365.0, "LOE3 1.fq.gz", "0:150 1:150", "A:1965670426;C:1773372970;G:1762457648;T:1955346803;N:361653", 150, 150, null, null, 1965670426, 1773372970, 1762457648, 1955346803, 361653, "SRX21793734", "SRS18895475", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.89541, 0.89576, 0.04195, 0.04177, 0.82536, 0.82375, 0.53368, 0.5374, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26526, "SRR26078870", "SRX21793733", "SRS18895474", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "liver specific overexpression of Igfbp7 2", "LOE replicate 2", null, "strain:transgenic strain|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:LOE replicate=biological replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "liver specific overexpression of Igfbp7 2", "LOE2", "LOE2", "liver specific overexpression of Igfbp7 2", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "LOE2_1.fq.gz LOE2_2.fq.gz", "fastq fastq", 7069059900.0, 23563533.0, "LOE2 1.fq.gz", "0:150 1:150", "A:1835774064;C:1704925495;G:1698942360;T:1829075424;N:342557", 150, 150, null, null, 1835774064, 1704925495, 1698942360, 1829075424, 342557, "SRX21793733", "SRS18895474", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.89965, 0.90019, 0.0524, 0.05247, 0.80669, 0.80525, 0.53582, 0.49543, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26527, "SRR26078871", "SRX21793732", "SRS18895473", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "liver specific overexpression of Igfbp7 1", "LOE replicate 1", null, "strain:transgenic strain|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:LOE replicate=biological replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "liver specific overexpression of Igfbp7 1", "LOE1", "LOE1", "liver specific overexpression of Igfbp7 1", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "LOE1_1.fq.gz LOE1_2.fq.gz", "fastq fastq", 7110174300.0, 23700581.0, "LOE1 1.fq.gz", "0:150 1:150", "A:1847016218;C:1713941614;G:1708466537;T:1840442742;N:307189", 150, 150, null, null, 1847016218, 1713941614, 1708466537, 1840442742, 307189, "SRX21793732", "SRS18895473", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.8999, 0.89917, 0.04883, 0.04874, 0.80858, 0.80716, 0.51686, 0.52442, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26528, "SRR26078872", "SRX21793731", "SRS18895469", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "Igfbp7 Konckout 3", "KO replicate 3", null, "strain:mutant|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:KO replicate=biological replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Igfbp7 Konckout 3", "KO3", "KO3", "Igfbp7 Konckout 3", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "KO3_1.fq.gz KO3_2.fq.gz", "fastq fastq", 6966225300.0, 23220751.0, "KO3 1.fq.gz", "0:150 1:150", "A:1854162705;C:1635332068;G:1634647432;T:1841746656;N:336439", 150, 150, null, null, 1854162705, 1635332068, 1634647432, 1841746656, 336439, "SRX21793731", "SRS18895469", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.94279, 0.94294, 0.0551, 0.05481, 0.78861, 0.78739, 0.54327, 0.50468, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26529, "SRR26078873", "SRX21793730", "SRS18895470", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "Igfbp7 Konckout 2", "KO replicate 2", null, "strain:mutant|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:KO replicate=biological replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Igfbp7 Konckout 2", "KO2", "KO2", "Igfbp7 Konckout 2", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "KO2_1.fq.gz KO2_2.fq.gz", "fastq fastq", 7465655100.0, 24885517.0, "KO2 1.fq.gz", "0:150 1:150", "A:1988715771;C:1750416778;G:1753335257;T:1972838856;N:348438", 150, 150, null, null, 1988715771, 1750416778, 1753335257, 1972838856, 348438, "SRX21793730", "SRS18895470", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.94231, 0.94227, 0.04975, 0.04965, 0.802, 0.80018, 0.50781, 0.54557, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26530, "SRR26078874", "SRX21793729", "SRS18895472", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "Igfbp7 Konckout 1", "KO replicate 1", null, "strain:mutant|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:KO replicate=biological replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Igfbp7 Konckout 1", "KO1", "KO1", "Igfbp7 Konckout 1", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "KO1_1.fq.gz KO1_2.fq.gz", "fastq fastq", 7208655000.0, 24028850.0, "KO1 1.fq.gz", "0:150 1:150", "A:1937720737;C:1672178897;G:1677582029;T:1920894866;N:278471", 150, 150, null, null, 1937720737, 1672178897, 1677582029, 1920894866, 278471, "SRX21793729", "SRS18895472", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.93429, 0.93361, 0.05126, 0.05122, 0.80827, 0.80718, 0.48739, 0.49469, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26531, "SRR26078875", "SRX21793728", "SRS18895471", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "wild type 3", "WT replicate 3", null, "strain:wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:WT replicate=biological replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "wild type 3", "WT3", "WT3", "wild type 3", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "WT3_1.fq.gz WT3_2.fq.gz", "fastq fastq", 7267116600.0, 24223722.0, "WT3 1.fq.gz", "0:150 1:150", "A:1946606247;C:1693037772;G:1694230444;T:1932894815;N:347322", 150, 150, null, null, 1946606247, 1693037772, 1694230444, 1932894815, 347322, "SRX21793728", "SRS18895471", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.94026, 0.94007, 0.05203, 0.05132, 0.79622, 0.79393, 0.52332, 0.51051, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26532, "SRR26078876", "SRX21793727", "SRS18895467", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "wild type 2", "WT replicate 2", null, "strain:wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:WT replicate=biological replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "wild type 2", "WT2", "WT2", "wild type 2", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "WT2_1.fq.gz WT2_2.fq.gz", "fastq fastq", 7206849900.0, 24022833.0, "WT2 1.fq.gz", "0:150 1:150", "A:1947268148;C:1660088486;G:1665583448;T:1933561073;N:348745", 150, 150, null, null, 1947268148, 1660088486, 1665583448, 1933561073, 348745, "SRX21793727", "SRS18895467", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.93368, 0.93327, 0.06754, 0.06713, 0.78681, 0.7861, 0.53133, 0.53795, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [26533, "SRR26078877", "SRX21793726", "SRS18895468", "SRP461206", "PRJNA1018104", "Global liver transcriptome assay of WT  Igfbp7 null mutant and Igfbp7 LOE animals", "PRJNA1018104", "Other", "The global increased expression of Insulin like growth factor binding protein 7 IGFBP7 has been detected in non alcoholic fatty liver disease NAFLD patients  however  its roles in NAFLD and the mechanism remain largely unclear. The goal of this study is to investigate the effect and mechanism of Igfbp7 using a zebrafish NAFLD model. The igfbp7 /  null zebrafish mutant and the Igfbp7 liver overexpressed LOE transgenic zebrafish based on Gal4/UAS system were generated by CRISPR/Cas9 and Tol2 transgenic technique  respectively. The zebrafish NAFLD models in wildtypes  igfbp7 /  mutants and Igfbp7 LOE fishes have been established by high fat diet feeding. The Igfbp7 dynamic expression and its effects on NAFLD progression have been detected and analyzed in both human NAFLD patients and zebrafish models. And the potential mechanism has been investigated through transcriptome analysis and subsequent detection and verification.", null, null, null, "wild type 1", "WT replicate 1", null, "strain:wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:not applicable|age:3 mpf|dev stage:adult|collection date:2021 10 09|geo loc name:China:Shanxi|sex:male|tissue:Liver|biomaterial provider:Zebrafish Facility of the Institute of Biomedical Sciences  Shanxi University|birth date:09 Jun 2021|birth location:China:Shanxi|breeding history:Fishes were fed 4 times per day with a high fat diet|breeding method:a high fat diet  in which 5% cholesterol was added to the standard diet feed type:Marvbeni C1  corresponding to 40 mg/fish/day|replicate:WT replicate=biological replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "wild type 1", "WT1", "WT1", "wild type 1", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "Illumina NovaSeq 6000", null, "SRP461206", null, null, "WT1_1.fq.gz WT1_2.fq.gz", "fastq fastq", 7170532200.0, 23901774.0, "WT1 1.fq.gz", "0:150 1:150", "A:1931584106;C:1658793663;G:1662799956;T:1917012316;N:342159", 150, 150, null, null, 1931584106, 1658793663, 1662799956, 1917012316, 342159, "SRX21793726", "SRS18895468", "SRA1713671", "First Hospital of Shanxi Medical University|Department of Gastroenterology and Hepatology", "First Hospital of Shanxi Medical University", 2, 0.93456, 0.93372, 0.06482, 0.06467, 0.77327, 0.77266, 0.52308, 0.53023, 150, 150, "B", "B", "biological fallback assumption", "illumina", "novaseq_era", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2023-09-16", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28496, "SRR26321412", "SRX22029502", "SRS19102283", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "3dpci 1", "R27", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 3 dpci", "R27", "R27", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R27.fastq", "fastq", 23400.0, 312.0, "R27.fastq", "0:75", "A:7949;C:4612;G:4730;T:6100;N:9", 75, null, null, null, 7949, 4612, 4730, 6100, 9, "SRX22029502", "SRS19102283", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.89642, null, 0.06772, null, 0.99827, null, 0.75, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28497, "SRR26321413", "SRX22029501", "SRS19102284", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "1dpci 4", "R22", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 1 dpci", "R22", "R22", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R22.fastq", "fastq", 23400.0, 312.0, "R22.fastq", "0:75", "A:7470;C:4460;G:5063;T:6404;N:3", 75, null, null, null, 7470, 4460, 5063, 6404, 3, "SRX22029501", "SRS19102284", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.87073, null, 0.12167, null, 0.99801, null, 0.73157, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28498, "SRR26321414", "SRX22029500", "SRS19102281", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "R21", "R21", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 1 dpci", "R21", "R21", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R21.fastq", "fastq", 23400.0, 312.0, "R21.fastq", "0:75", "A:7540;C:4349;G:4857;T:6646;N:8", 75, null, null, null, 7540, 4349, 4857, 6646, 8, "SRX22029500", "SRS19102281", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.8839, null, 0.04494, null, 0.99768, null, 0.72769, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28499, "SRR26321415", "SRX22029499", "SRS19102282", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "1dpci 2", "R18", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 1 dpci", "R18", "R18", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R18.fastq", "fastq", 23400.0, 312.0, "R18.fastq", "0:75", "A:7380;C:4430;G:5069;T:6518;N:3", 75, null, null, null, 7380, 4430, 5069, 6518, 3, "SRX22029499", "SRS19102282", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.87259, null, 0.11196, null, 0.99784, null, 0.69791, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28500, "SRR26321416", "SRX22029498", "SRS19102280", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "1dpci 1", "R17", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 1 dpci", "R17", "R17", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R17.fastq", "fastq", 23400.0, 312.0, "R17.fastq", "0:75", "A:7322;C:4455;G:5111;T:6507;N:5", 75, null, null, null, 7322, 4455, 5111, 6507, 5, "SRX22029498", "SRS19102280", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.90439, null, 0.12749, null, 0.99813, null, 0.71052, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28501, "SRR26321417", "SRX22029497", "SRS19102279", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "SHAM 5", "R1", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver sham", "R1", "R1", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R1.fastq", "fastq", 23400.0, 312.0, "R1.fastq", "0:75", "A:7934;C:4560;G:4922;T:5980;N:4", 75, null, null, null, 7934, 4560, 4922, 5980, 4, "SRX22029497", "SRS19102279", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.87045, null, 0.10526, null, 0.99805, null, 0.71978, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28502, "SRR26321418", "SRX22029496", "SRS19102277", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "SHAM 4", "R64", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver sham", "R64", "R64", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R64.fastq", "fastq", 23400.0, 312.0, "R64.fastq", "0:75", "A:7844;C:4626;G:4804;T:6126;N:0", 75, null, null, null, 7844, 4626, 4804, 6126, 0, "SRX22029496", "SRS19102277", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.90119, null, 0.07509, null, 0.99839, null, 0.8, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28503, "SRR26321419", "SRX22029495", "SRS19102278", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "SHAM 3", "R61", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver sham", "R61", "R61", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R61.fastq", "fastq", 23400.0, 312.0, "R61.fastq", "0:75", "A:7454;C:4556;G:4960;T:6425;N:5", 75, null, null, null, 7454, 4556, 4960, 6425, 5, "SRX22029495", "SRS19102278", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.89098, null, 0.06015, null, 0.99813, null, 0.77102, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28504, "SRR26321420", "SRX22029494", "SRS19102276", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "7dpci 4", "30", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 7 dpci", "30", "30", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "30.fastq", "fastq", 23400.0, 312.0, "30.fastq", "0:75", "A:7732;C:4528;G:5150;T:5987;N:3", 75, null, null, null, 7732, 4528, 5150, 5987, 3, "SRX22029494", "SRS19102276", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.88447, null, 0.13147, null, 0.99772, null, 0.71584, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28505, "SRR26321421", "SRX22029493", "SRS19102275", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "R11", "R11", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 7 dpci", "R11", "R11", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R11.fastq", "fastq", 23400.0, 312.0, "R11.fastq", "0:75", "A:7818;C:4507;G:5107;T:5956;N:12", 75, null, null, null, 7818, 4507, 5107, 5956, 12, "SRX22029493", "SRS19102275", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.89345, null, 0.11475, null, 0.99847, null, 0.82258, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28506, "SRR26321422", "SRX22029492", "SRS19102274", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "7dpci 2", "31", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 7 dpci", "31", "31", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "31.fastq", "fastq", 23400.0, 312.0, "31.fastq", "0:75", "A:7470;C:4619;G:4802;T:6504;N:5", 75, null, null, null, 7470, 4619, 4802, 6504, 5, "SRX22029492", "SRS19102274", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.87699, null, 0.11111, null, 0.99829, null, 0.78918, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28507, "SRR26321423", "SRX22029491", "SRS19102273", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "7dpci 1", "R9", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 7 dpci", "R9", "R9", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R9.fastq", "fastq", 23400.0, 312.0, "R9.fastq", "0:75", "A:8130;C:4537;G:4809;T:5917;N:7", 75, null, null, null, 8130, 4537, 4809, 5917, 7, "SRX22029491", "SRS19102273", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.83588, null, 0.05725, null, 0.99801, null, 0.68586, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28508, "SRR26321424", "SRX22029490", "SRS19102272", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "3dpci 4", "R33", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 3 dpci", "R33", "R33", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R33.fastq", "fastq", 23400.0, 312.0, "R33.fastq", "0:75", "A:7745;C:4421;G:4867;T:6360;N:7", 75, null, null, null, 7745, 4421, 4867, 6360, 7, "SRX22029490", "SRS19102272", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.87259, null, 0.07335, null, 0.99805, null, 0.71428, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28509, "SRR26321425", "SRX22029489", "SRS19102271", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "3dpci 3", "R31", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 3 dpci", "R31", "R31", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R31.fastq", "fastq", 23400.0, 312.0, "R31.fastq", "0:75", "A:7441;C:4483;G:5163;T:6313;N:0", 75, null, null, null, 7441, 4483, 5163, 6313, 0, "SRX22029489", "SRS19102271", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.9, null, 0.05925, null, 0.9977, null, 0.68325, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28510, "SRR26321426", "SRX22029488", "SRS19102270", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "3dpci 2", "R29", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver 3 dpci", "R29", "R29", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R29.fastq", "fastq", 23400.0, 312.0, "R29.fastq", "0:75", "A:7379;C:4698;G:5166;T:6156;N:1", 75, null, null, null, 7379, 4698, 5166, 6156, 1, "SRX22029488", "SRS19102270", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.91016, null, 0.05859, null, 0.99797, null, 0.74528, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28511, "SRR26321427", "SRX22029487", "SRS19102269", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, null, "SHAM 2", "R62", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver sham", "R62", "R62", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R62.fastq", "fastq", 23400.0, 312.0, "R62.fastq", "0:75", "A:7383;C:4566;G:4713;T:6728;N:10", 75, null, null, null, 7383, 4566, 4713, 6728, 10, "SRX22029487", "SRS19102269", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.91571, null, 0.05363, null, 0.99835, null, 0.77674, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [28512, "SRR26321428", "SRX22029486", "SRS19102268", "SRP465132", "PRJNA1025903", "Zebrafish cryoinjury regeneration Raw sequence reads", "PRJNA1025903", "Whole Genome Sequencing", "Bulk RNA seq collection of adult zebrafish livers at different stages of regeneration upon liver croyinjury", null, null, "Replicate 1 for SHAM", "SHAM 1", "R63", null, "strain:AB|isolate:missing|breed:missing|cultivar:missing|ecotype:missing|age:9 month|dev stage:maturity|collection date:2021 07 24|geo loc name:Australia: Melbourne|sex:male|tissue:Liver|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA seq of zebrafish liver sham", "R63", "R63", "ham and injured livers at 1  3  and 7 dpci were phenotyped under the fluorescent stereomicroscope NSZ 606 Binocular Zoom fitted with a NightSea SFA light base to confirm the presence of insult upon cryoinjury. In addition  3 adult zebrafish livers were pooled per tube  discriminating between the injured border and liver tissue from other lobes. Finally  3 replicates of 3 pooled livers were used for library preparation. Livers were transferred to a final volume of 300uL of cold TRIzolTM Thermo Fisher Scientific per tube on ice. Livers were homogenized using the mechanical homogenizer for 30s on ice  with a plastic pestle  to ensure fine homogenization. RNA was extracted according to the manufacturer guidelines Direct zolTM RNA MiniPrep kit  Zymo Research. RNA quality was confirmed using an Agilent 4200 Tapestation System. Libraries were sequenced in Illumina NextSeq 500  with paired end 75bp reads to a depth of 15M reads per sample.", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PCR", "SINGLE", "ILLUMINA", "NextSeq 500", null, "SRP465132", null, null, "R63.fastq", "fastq", 23400.0, 312.0, "R63.fastq", "0:75", "A:7516;C:4606;G:4765;T:6508;N:5", 75, null, null, null, 7516, 4606, 4765, 6508, 5, "SRX22029486", "SRS19102268", "SRA1727674", "Peter MacCallum Cancer Centre|Organogenesis and Cancer", "Peter MacCallum Cancer Centre", 1, 0.90385, null, 0.0423, null, 0.99805, null, 0.72429, null, 75, null, "B", null, "usable mapping rate", "illumina", "nextseq", "unknown", "random_priming", "unknown", "bulk", "bulk", "bulk", null, "Australia", "2023-10-11", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29581, "SRR27387424", "SRX23063703", "SRS20023725", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Control Liver", "control liver 5", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:control liver replicate5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T1 5", "T1 5", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A7_1.fastq.gz A7_2.fastq.gz", "fastq fastq", 7139648700.0, 23798829.0, "A7 1.fastq.gz", "0:150 1:150", "A:1898040242;C:1678584917;G:1680422296;T:1882535161;N:66084", 150, 150, null, null, 1898040242, 1678584917, 1680422296, 1882535161, 66084, "SRX23063703", "SRS20023725", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94633, 0.94658, 0.04866, 0.0489, 0.77098, 0.77041, 0.48393, 0.49328, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29592, "SRR27387435", "SRX23063692", "SRS20023714", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Control Liver", "control liver 4", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:control liver replicate4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T1 4", "T1 4", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A6_1.fastq.gz A6_2.fastq.gz", "fastq fastq", 7080291000.0, 23600970.0, "A6 1.fastq.gz", "0:150 1:150", "A:1890410803;C:1656924196;G:1658022500;T:1874867839;N:65662", 150, 150, null, null, 1890410803, 1656924196, 1658022500, 1874867839, 65662, "SRX23063692", "SRS20023714", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94344, 0.94345, 0.05044, 0.05028, 0.7683, 0.76838, 0.48933, 0.49113, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29600, "SRR27387443", "SRX23063684", "SRS20023706", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Combined Liver", "combined liver 6", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:combined liver replicate6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T4 6", "T4 6", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A21_1.fastq.gz A21_2.fastq.gz", "fastq fastq", 8613810000.0, 28712700.0, "A21 1.fastq.gz", "0:150 1:150", "A:2301535821;C:2013247658;G:2021540738;T:2277424933;N:60850", 150, 150, null, null, 2301535821, 2013247658, 2021540738, 2277424933, 60850, "SRX23063684", "SRS20023706", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94372, 0.94375, 0.04559, 0.04554, 0.80397, 0.80446, 0.54615, 0.54931, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29601, "SRR27387444", "SRX23063683", "SRS20023705", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Combined Liver", "combined liver 5", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:combined liver replicate5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T4 5", "T4 5", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A20_1.fastq.gz A20_2.fastq.gz", "fastq fastq", 7660898400.0, 25536328.0, "A20 1.fastq.gz", "0:150 1:150", "A:2045662664;C:1793844486;G:1797425064;T:2023911614;N:54572", 150, 150, null, null, 2045662664, 1793844486, 1797425064, 2023911614, 54572, "SRX23063683", "SRS20023705", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94307, 0.94399, 0.04996, 0.04972, 0.79916, 0.79967, 0.55321, 0.55159, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29602, "SRR27387445", "SRX23063682", "SRS20023704", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Combined Liver", "combined liver 4", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:combined liver replicate4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T4 4", "T4 4", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A19_1.fastq.gz A19_2.fastq.gz", "fastq fastq", 8492667000.0, 28308890.0, "A19 1.fastq.gz", "0:150 1:150", "A:2287240764;C:1972022212;G:1977128547;T:2256183819;N:91658", 150, 150, null, null, 2287240764, 1972022212, 1977128547, 2256183819, 91658, "SRX23063682", "SRS20023704", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94222, 0.94087, 0.05048, 0.05023, 0.78847, 0.7876, 0.54394, 0.54327, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29603, "SRR27387446", "SRX23063681", "SRS20023703", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Control Liver", "control liver 3", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:control liver replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T1 3", "T1 3", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A5_1.fastq.gz A5_2.fastq.gz", "fastq fastq", 6365746500.0, 21219155.0, "A5 1.fastq.gz", "0:150 1:150", "A:1680943294;C:1504416528;G:1516780057;T:1663547544;N:59077", 150, 150, null, null, 1680943294, 1504416528, 1516780057, 1663547544, 59077, "SRX23063681", "SRS20023703", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.96138, 0.96072, 0.01946, 0.01949, 0.84372, 0.84437, 0.21657, 0.2162, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29604, "SRR27387447", "SRX23063680", "SRS20023702", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Combined Liver", "combined liver 3", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:combined liver replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T4 3", "T4 3", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A18_1.fastq.gz A18_2.fastq.gz", "fastq fastq", 6080801100.0, 20269337.0, "A18 1.fastq.gz", "0:150 1:150", "A:1625543543;C:1426271281;G:1432771006;T:1596174300;N:40970", 150, 150, null, null, 1625543543, 1426271281, 1432771006, 1596174300, 40970, "SRX23063680", "SRS20023702", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94461, 0.94384, 0.04104, 0.04107, 0.81294, 0.81369, 0.55086, 0.55066, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29605, "SRR27387448", "SRX23063679", "SRS20023701", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Combined Liver", "combined liver 2", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:combined liver replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T4 2", "T4 2", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A17_1.fastq.gz A17_2.fastq.gz", "fastq fastq", 8357049600.0, 27856832.0, "A17 1.fastq.gz", "0:150 1:150", "A:2228408702;C:1962845144;G:1962818306;T:2202917758;N:59690", 150, 150, null, null, 2228408702, 1962845144, 1962818306, 2202917758, 59690, "SRX23063679", "SRS20023701", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94277, 0.9436, 0.0454, 0.04526, 0.76039, 0.76012, 0.53857, 0.49252, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29606, "SRR27387449", "SRX23063678", "SRS20023700", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Combined Liver", "combined liver 1", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:combined liver replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T4 1", "T4 1", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A16_1.fastq.gz A16_2.fastq.gz", "fastq fastq", 8697886500.0, 28992955.0, "A16 1.fastq.gz", "0:150 1:150", "A:2308292580;C:2052173268;G:2056418654;T:2280941830;N:60168", 150, 150, null, null, 2308292580, 2052173268, 2056418654, 2280941830, 60168, "SRX23063678", "SRS20023700", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94941, 0.95075, 0.03814, 0.03814, 0.80359, 0.80511, 0.45866, 0.46697, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29607, "SRR27387450", "SRX23063677", "SRS20023699", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Nanoplastics Liver", "nps liver 6", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:nps liver replicate6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T3 6", "T3 6", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A14_1.fastq.gz A14_2.fastq.gz", "fastq fastq", 6328078200.0, 21093594.0, "A14 1.fastq.gz", "0:150 1:150", "A:1651110799;C:1522543378;G:1523353407;T:1631026281;N:44335", 150, 150, null, null, 1651110799, 1522543378, 1523353407, 1631026281, 44335, "SRX23063677", "SRS20023699", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.95918, 0.95893, 0.03288, 0.03279, 0.7989, 0.79892, 0.46602, 0.44771, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29608, "SRR27387451", "SRX23063676", "SRS20023698", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Nanoplastics Liver", "nps liver 5", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:nps liver replicate5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T3 5", "T3 5", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A13_1.fastq.gz A13_2.fastq.gz", "fastq fastq", 6682736400.0, 22275788.0, "A13 1.fastq.gz", "0:150 1:150", "A:1770006493;C:1580541555;G:1583340681;T:1748799643;N:48028", 150, 150, null, null, 1770006493, 1580541555, 1583340681, 1748799643, 48028, "SRX23063676", "SRS20023698", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94674, 0.94767, 0.04088, 0.04069, 0.79362, 0.79326, 0.51807, 0.55709, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29609, "SRR27387452", "SRX23063675", "SRS20023697", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Nanoplastics Liver", "nps liver 4", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:nps liver replicate4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T3 4", "T3 4", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A12_1.fastq.gz A12_2.fastq.gz", "fastq fastq", 7223844300.0, 24079481.0, "A12 1.fastq.gz", "0:150 1:150", "A:1898044988;C:1723221670;G:1728581768;T:1873946251;N:49623", 150, 150, null, null, 1898044988, 1723221670, 1728581768, 1873946251, 49623, "SRX23063675", "SRS20023697", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.95897, 0.9583, 0.03099, 0.03094, 0.81359, 0.81414, 0.36697, 0.38046, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29610, "SRR27387453", "SRX23063674", "SRS20023696", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Nanoplastics Liver", "nps liver 3", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:nps liver replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T3 3", "T3 3", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A11_1.fastq.gz A11_2.fastq.gz", "fastq fastq", 7712327100.0, 25707757.0, "A11 1.fastq.gz", "0:150 1:150", "A:2078269634;C:1786227652;G:1790988947;T:2056786923;N:53944", 150, 150, null, null, 2078269634, 1786227652, 1790988947, 2056786923, 53944, "SRX23063674", "SRS20023696", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.93754, 0.93849, 0.05229, 0.05261, 0.79762, 0.79841, 0.52961, 0.55954, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29611, "SRR27387454", "SRX23063673", "SRS20023695", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Nanoplastics Liver", "nps liver 2", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:nps liver replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T3 2", "T3 2", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A10_1.fastq.gz A10_2.fastq.gz", "fastq fastq", 9006367500.0, 30021225.0, "A10 1.fastq.gz", "0:150 1:150", "A:2405095208;C:2108519804;G:2119356079;T:2373332498;N:63911", 150, 150, null, null, 2405095208, 2108519804, 2119356079, 2373332498, 63911, "SRX23063673", "SRS20023695", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.93857, 0.93907, 0.04235, 0.04254, 0.74401, 0.74442, 0.53865, 0.54012, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29612, "SRR27387455", "SRX23063672", "SRS20023694", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Nanoplastics Liver", "nps liver 1", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:nps liver replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T3 1", "T3 1", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A8_1.fastq.gz A8_2.fastq.gz", "fastq fastq", 9705357300.0, 32351191.0, "A8 1.fastq.gz", "0:150 1:150", "A:2549361250;C:2315598558;G:2319533236;T:2520797865;N:66391", 150, 150, null, null, 2549361250, 2315598558, 2319533236, 2520797865, 66391, "SRX23063672", "SRS20023694", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.95257, 0.95219, 0.03953, 0.03882, 0.80085, 0.80052, 0.5024, 0.50544, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29613, "SRR27387456", "SRX23063671", "SRS20023693", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "6PPDQ Liver", "6ppdq liver 6", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:6ppdq liver replicate6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T2 6", "T2 6", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A28_1.fastq.gz A28_2.fastq.gz", "fastq fastq", 7312027200.0, 24373424.0, "A28 1.fastq.gz", "0:150 1:150", "A:1933027768;C:1734543239;G:1734058319;T:1910343929;N:53945", 150, 150, null, null, 1933027768, 1734543239, 1734058319, 1910343929, 53945, "SRX23063671", "SRS20023693", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94984, 0.95024, 0.04435, 0.04424, 0.77804, 0.77869, 0.5448, 0.51681, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29614, "SRR27387457", "SRX23063670", "SRS20023692", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Control Liver", "control liver 2", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:control liver replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T1 2", "T1 2", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A3_1.fastq.gz A3_2.fastq.gz", "fastq fastq", 10383955200.0, 34613184.0, "A3 1.fastq.gz", "0:150 1:150", "A:2778093066;C:2424701453;G:2429080701;T:2751982231;N:97749", 150, 150, null, null, 2778093066, 2424701453, 2429080701, 2751982231, 97749, "SRX23063670", "SRS20023692", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94514, 0.94539, 0.05128, 0.05171, 0.80697, 0.80669, 0.55446, 0.54855, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29615, "SRR27387458", "SRX23063669", "SRS20023691", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "Control Liver", "control liver 1", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:control liver replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T1 1", "T1 1", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A1_1.fastq.gz A1_2.fastq.gz", "fastq fastq", 6990799500.0, 23302665.0, "A1 1.fastq.gz", "0:150 1:150", "A:1852168539;C:1650230337;G:1654609197;T:1833725714;N:65713", 150, 150, null, null, 1852168539, 1650230337, 1654609197, 1833725714, 65713, "SRX23063669", "SRS20023691", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.95142, 0.95049, 0.03481, 0.03455, 0.80955, 0.81089, 0.42523, 0.42786, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29616, "SRR27387459", "SRX23063668", "SRS20023690", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "6PPDQ Liver", "6ppdq liver 5", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:6ppdq liver replicate5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T2 5", "T2 5", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A27_1.fastq.gz A27_2.fastq.gz", "fastq fastq", 8327205000.0, 27757350.0, "A27 1.fastq.gz", "0:150 1:150", "A:2188059959;C:1983666022;G:1992428805;T:2162994610;N:55604", 150, 150, null, null, 2188059959, 1983666022, 1992428805, 2162994610, 55604, "SRX23063668", "SRS20023690", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.95557, 0.95521, 0.03496, 0.035, 0.81377, 0.81428, 0.44899, 0.45358, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29617, "SRR27387460", "SRX23063667", "SRS20023689", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "6PPDQ Liver", "6ppdq liver 4", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:6ppdq liver replicate4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T2 4", "T2 4", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A26_1.fastq.gz A26_2.fastq.gz", "fastq fastq", 6407337900.0, 21357793.0, "A26 1.fastq.gz", "0:150 1:150", "A:1685351213;C:1524796223;G:1531286302;T:1665857949;N:46213", 150, 150, null, null, 1685351213, 1524796223, 1531286302, 1665857949, 46213, "SRX23063667", "SRS20023689", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.96413, 0.96363, 0.02797, 0.02805, 0.8505, 0.85194, 0.38255, 0.38447, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29618, "SRR27387461", "SRX23063666", "SRS20023688", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "6PPDQ Liver", "6ppdq liver 3", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:6ppdq liver replicate3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T2 3", "T2 3", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A25_1.fastq.gz A25_2.fastq.gz", "fastq fastq", 8578160400.0, 28593868.0, "A25 1.fastq.gz", "0:150 1:150", "A:2253186424;C:2047305045;G:2050974170;T:2226633669;N:61092", 150, 150, null, null, 2253186424, 2047305045, 2050974170, 2226633669, 61092, "SRX23063666", "SRS20023688", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.95088, 0.95107, 0.04217, 0.04231, 0.77875, 0.77922, 0.5388, 0.53743, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29619, "SRR27387462", "SRX23063665", "SRS20023687", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "6PPDQ Liver", "6ppdq liver 2", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:6ppdq liver replicate2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T2 2", "T2 2", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A23_1.fastq.gz A23_2.fastq.gz", "fastq fastq", 7606031100.0, 25353437.0, "A23 1.fastq.gz", "0:150 1:150", "A:2040128163;C:1774614072;G:1775629532;T:2015605795;N:53538", 150, 150, null, null, 2040128163, 1774614072, 1775629532, 2015605795, 53538, "SRX23063665", "SRS20023687", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.945, 0.94581, 0.04313, 0.04324, 0.81617, 0.8172, 0.55094, 0.55944, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [29620, "SRR27387463", "SRX23063664", "SRS20023686", "SRP480720", "PRJNA1059246", "Mixture toxicity of 6PPD quinone and polystyrene nanoplastics in zebrafish", "PRJNA1059246", "Other", "Tyre wear particles are the second largest source of microplastics in the ocean following abrasion of synthetic fibres. In addition to the particles themselves  TWPs contain many harmful chemicals  including 6PPD. This chemical reacts with atmospheric ozone and forms the toxic compound 6PPD quinone  which poses a danger to aquatic life. There is a knowledge gap in understanding risks associated with thecombined toxicity of nanoplastics and 6PPDq. The present study aimed to investigate the toxicity of NPs and 6PPDq on adult zebrafish. However  we found significant hyperlocomotion in zebrafish exposed to 6PPDq and this effect was even more substantial post co exposure with PSNPs. The more pronounced toxic response in coexposed zebrafish was also observed at the transcriptomic level. KEGG pathways analysis identified mitochondrial dysfunction in the intestine and metabolic disturbances in the liver. These results highlight the significance of mixture toxicity when studying the effects of NPs and associated chemicals like 6PPDq.", null, null, null, "6PPDQ Liver", "6ppdq liver 1", null, "strain:Wild type|isolate:not applicable|breed:not applicable|cultivar:not applicable|ecotype:laboratory|age:16 weeks|dev stage:adult|sex:male|tissue:liver|biomaterial provider:not applicable|birth date:not applicable|birth location:not applicable|breeding history:not applicable|breeding method:not applicable|cell line:not applicable|cell subtype:not applicable|cell type:not applicable|collected by:Shubham Varshney|collection date:2023 06|culture collection:not applicable|death date:not applicable|disease:not applicable|disease stg:not applicable|genotype:not applicable|geo loc name:not applicable|growth protocol:not applicable|health state:not applicable|isolation source:not applicable|lat lon:not applicable|phenotype:not applicable|sample type:not applicable|specimen voucher:not applicable|store cond:not applicable|stud book number:not applicable|treatment:6ppdq liver replicate1|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "RNA Seq of zebrafish", "T2 1", "T2 1", "PCR enrichment of adaptor ligated DNA", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "ILLUMINA", "NextSeq 550", null, "SRP480720", null, null, "A22_1.fastq.gz A22_2.fastq.gz", "fastq fastq", 6116767200.0, 20389224.0, "A22 1.fastq.gz", "0:150 1:150", "A:1642510559;C:1422754642;G:1431247073;T:1620185548;N:69378", 150, 150, null, null, 1642510559, 1422754642, 1431247073, 1620185548, 69378, "SRX23063664", "SRS20023686", "SRA1777576", "Nord University|Faculty of Biosciences and Aquaculture", "Nord University", 2, 0.94746, 0.9454, 0.0432, 0.04289, 0.80748, 0.80752, 0.56194, 0.55666, 150, 150, "B", "B", "biological fallback assumption", "illumina", "nextseq", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "Norway", "2023-12-30", "Adult", "Adult", "Liver", "Liver and Biliary System"], [31980, "SRR28892728", "SRX24451189", "SRS21204958", "SRP505641", "PRJNA1107713", "Tea polyphenols induce hepatotoxicity by interfering with adult zebrafish lipid metabolism and gut microbiota through the gut liver axis", "PRJNA1107713", "Other", "High dose tea polyphenols may promote fatty acid absorption by hepatocytes by up regulating FABP  CD36 and SRB1 genes  inhibiting fatty acid efflux by down regulating ABCA1 genes  and inhibiting fatty acid beta oxidation by down regulating CPT1 and ACAA2 genes  resulting in fat accumulation in hepatocytes  upregulation of inflammatory pathways  and increased expression of pro inflammatory factors TNF a and IL1 b.", null, null, null, null, "TP3", null, "strain:not applicable|isolate:not applicable|breed:not collected|cultivar:not applicable|ecotype:AB ecotype|age:5 month|collection date:2022 11 24|geo loc name:China|sex:male|tissue:liver|replicate:replicate=biological replicate 6|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Adult zebrafish liver", "TP3", "TP3", "mRNAseq of zebrafish liver  replication 3 of TP", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "DNBSEQ", "DNBSEQ-T7", null, "SRP505641", null, null, "TP3_1.fq.gz TP3_2.fq.gz", "fastq fastq", 6657069900.0, 22190233.0, "TP3 1.fq.gz", "0:150 1:150", "A:1808410149;C:1512668682;G:1536153888;T:1799837181;N:0", 150, 150, null, null, 1808410149, 1512668682, 1536153888, 1799837181, 0, "SRX24451189", "SRS21204958", "SRA1858747", "Beibu Gulf University|college of Food Engineering", "Beibu Gulf University", null, null, null, null, null, null, null, null, null, null, null, "B", "B", "biological fallback assumption", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2024-05-04", "Adult", "Adult", "Liver", "Liver and Biliary System"], [31981, "SRR28892729", "SRX24451188", "SRS21204959", "SRP505641", "PRJNA1107713", "Tea polyphenols induce hepatotoxicity by interfering with adult zebrafish lipid metabolism and gut microbiota through the gut liver axis", "PRJNA1107713", "Other", "High dose tea polyphenols may promote fatty acid absorption by hepatocytes by up regulating FABP  CD36 and SRB1 genes  inhibiting fatty acid efflux by down regulating ABCA1 genes  and inhibiting fatty acid beta oxidation by down regulating CPT1 and ACAA2 genes  resulting in fat accumulation in hepatocytes  upregulation of inflammatory pathways  and increased expression of pro inflammatory factors TNF a and IL1 b.", null, null, null, null, "TP2", null, "strain:not applicable|isolate:not applicable|breed:not collected|cultivar:not applicable|ecotype:AB ecotype|age:5 month|collection date:2022 11 24|geo loc name:China|sex:male|tissue:liver|replicate:replicate=biological replicate 5|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Adult zebrafish liver", "TP2", "TP2", "mRNAseq of zebrafish liver  replication 2 of TP", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "DNBSEQ", "DNBSEQ-T7", null, "SRP505641", null, null, "TP2_1.fq.gz TP2_2.fq.gz", "fastq fastq", 6617368500.0, 22057895.0, "TP2 1.fq.gz", "0:150 1:150", "A:1799646726;C:1503407966;G:1523443584;T:1790870224;N:0", 150, 150, null, null, 1799646726, 1503407966, 1523443584, 1790870224, 0, "SRX24451188", "SRS21204959", "SRA1858747", "Beibu Gulf University|college of Food Engineering", "Beibu Gulf University", null, null, null, null, null, null, null, null, null, null, null, "B", "B", "biological fallback assumption", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2024-05-04", "Adult", "Adult", "Liver", "Liver and Biliary System"], [31982, "SRR28892730", "SRX24451187", "SRS21204956", "SRP505641", "PRJNA1107713", "Tea polyphenols induce hepatotoxicity by interfering with adult zebrafish lipid metabolism and gut microbiota through the gut liver axis", "PRJNA1107713", "Other", "High dose tea polyphenols may promote fatty acid absorption by hepatocytes by up regulating FABP  CD36 and SRB1 genes  inhibiting fatty acid efflux by down regulating ABCA1 genes  and inhibiting fatty acid beta oxidation by down regulating CPT1 and ACAA2 genes  resulting in fat accumulation in hepatocytes  upregulation of inflammatory pathways  and increased expression of pro inflammatory factors TNF a and IL1 b.", null, null, null, null, "TP1", null, "strain:not applicable|isolate:not applicable|breed:not collected|cultivar:not applicable|ecotype:AB ecotype|age:5 month|collection date:2022 11 24|geo loc name:China|sex:male|tissue:liver|replicate:replicate=biological replicate 4|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Adult zebrafish liver", "TP1", "TP1", "mRNAseq of zebrafish liver  replication 1 of TP", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "DNBSEQ", "DNBSEQ-T7", null, "SRP505641", null, null, "TP1_1.fq.gz TP1_2.fq.gz", "fastq fastq", 6432586800.0, 21441956.0, "TP1 1.fq.gz", "0:150 1:150", "A:1743341515;C:1465440262;G:1488109144;T:1735695879;N:0", 150, 150, null, null, 1743341515, 1465440262, 1488109144, 1735695879, 0, "SRX24451187", "SRS21204956", "SRA1858747", "Beibu Gulf University|college of Food Engineering", "Beibu Gulf University", null, null, null, null, null, null, null, null, null, null, null, "B", "B", "biological fallback assumption", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2024-05-04", "Adult", "Adult", "Liver", "Liver and Biliary System"], [31983, "SRR28892731", "SRX24451186", "SRS21204957", "SRP505641", "PRJNA1107713", "Tea polyphenols induce hepatotoxicity by interfering with adult zebrafish lipid metabolism and gut microbiota through the gut liver axis", "PRJNA1107713", "Other", "High dose tea polyphenols may promote fatty acid absorption by hepatocytes by up regulating FABP  CD36 and SRB1 genes  inhibiting fatty acid efflux by down regulating ABCA1 genes  and inhibiting fatty acid beta oxidation by down regulating CPT1 and ACAA2 genes  resulting in fat accumulation in hepatocytes  upregulation of inflammatory pathways  and increased expression of pro inflammatory factors TNF a and IL1 b.", null, null, null, null, "CONT3", null, "strain:not applicable|isolate:not applicable|breed:not collected|cultivar:not applicable|ecotype:AB ecotype|age:5 month|collection date:2022 11 24|geo loc name:China|sex:male|tissue:liver|replicate:replicate=biological replicate 3|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Adult zebrafish liver", "CON3", "CON3", "mRNAseq of zebrafish liver  replication 3 of CONT", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "DNBSEQ", "DNBSEQ-T7", null, "SRP505641", null, null, "CONT3_1.fq.gz CONT3_2.fq.gz", "fastq fastq", 6595768200.0, 21985894.0, "CONT3 1.fq.gz", "0:150 1:150", "A:1762107185;C:1525175684;G:1547321856;T:1761163475;N:0", 150, 150, null, null, 1762107185, 1525175684, 1547321856, 1761163475, 0, "SRX24451186", "SRS21204957", "SRA1858747", "Beibu Gulf University|college of Food Engineering", "Beibu Gulf University", null, null, null, null, null, null, null, null, null, null, null, "B", "B", "biological fallback assumption", "bgi", "bgi", "unknown", "poly_a", "unknown", "bulk", "unknown", "unknown", null, "China", "2024-05-04", "Adult", "Adult", "Liver", "Liver and Biliary System"], [31984, "SRR28892732", "SRX24451185", "SRS21204954", "SRP505641", "PRJNA1107713", "Tea polyphenols induce hepatotoxicity by interfering with adult zebrafish lipid metabolism and gut microbiota through the gut liver axis", "PRJNA1107713", "Other", "High dose tea polyphenols may promote fatty acid absorption by hepatocytes by up regulating FABP  CD36 and SRB1 genes  inhibiting fatty acid efflux by down regulating ABCA1 genes  and inhibiting fatty acid beta oxidation by down regulating CPT1 and ACAA2 genes  resulting in fat accumulation in hepatocytes  upregulation of inflammatory pathways  and increased expression of pro inflammatory factors TNF a and IL1 b.", null, null, null, null, "CONT2", null, "strain:not applicable|isolate:not applicable|breed:not collected|cultivar:not applicable|ecotype:AB ecotype|age:5 month|collection date:2022 11 24|geo loc name:China|sex:male|tissue:liver|replicate:replicate=biological replicate 2|BioSampleModel:Model organism or animal", null, null, null, null, null, null, null, null, "Adult zebrafish liver", "CON2", "CON2", "mRNAseq of zebrafish liver  replication 2 of CONT", null, null, "RNA-Seq", "TRANSCRIPTOMIC", "PolyA", "PAIRED", "DNBSEQ", "DNBSEQ-T7", null, "SRP505641", null, null, "CONT2_1.fq.gz CONT2_2.fq.gz", "fastq fastq", 6175346400.0, 20584488.0, "CONT2 1.fq.gz", "0:150 1:150", "A:1656546719;C:1421990443;G:1442409824;T:1654399414;N:0", 150, 150, null, null, 1656546719, 1421990443, 1442409824, 1654399414, 0, 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"submission.bioprojectsource.country", "earliest_date", "devstage_curation", "devstage_curation_coarse", "tissue_curation", "tissue_curation_coarse"], "primary_keys": [], "units": {}, "query": {"sql": "select rowid, [run.accession], [experiment.accession], [sample.accession], [study.accession], bioproject, [study.title], [study.alias], [study.type], [study.abstract], [study.attributes], [study.PMIDs], [sample.description], [sample.title], [sample.alias], [sample.centername], [sample.attributes], [GEOsample.title], [GEOsample.dataprocessing], [GEOsample.source], [GEOsample.treatmentprotocol], [GEOsample.extractprotocol], [GEOsample.growthprotocol], [GEOsample.characteristics], [GEOsample.accession], [experiment.title], [experiment.alias], [experiment.library_name], [experiment.design_description], [experiment.library_construction_protocol], [experiment.attributes], [experiment.library_strategy], [experiment.library_source], [experiment.library_selection], [experiment.library_layout], [experiment.platform], [experiment.instrument_model], [experiment.spot_descriptor], [experiment.study_ref], [run.title], [run.attributes], [run.filename], [run.semantic_name], [run.total_bases], [run.total_spots], [run.alias], [run.read_lengths], [run.base_counts], [run.r1_length], [run.r2_length], [run.r3_length], [run.r4_length], [run.Acount], [run.Ccount], [run.Gcount], [run.Tcount], [run.Ncount], [run.experiment], [run.pool_member], [submission.accession], [submission.srasource], [submission.bioprojectsource], [seqdetective.n_mates], [seqdetective.mapping_rate.mate1], [seqdetective.mapping_rate.mate2], [seqdetective.nofeature_rate.mate1], [seqdetective.nofeature_rate.mate2], [seqdetective.sparsity.mate1], [seqdetective.sparsity.mate2], [seqdetective.pos_strand_rate.mate1], [seqdetective.pos_strand_rate.mate2], [seqdetective.readlen.mate1], [seqdetective.readlen.mate2], [seqdetective.judgement.mate1], [seqdetective.judgement.mate2], [seqdetective.judgement.reason], platform_family, instrument_generation, read_bias, selection_class, prep_kit, sc_or_bulk, tech_class, technology, tech_variant, [submission.bioprojectsource.country], earliest_date, devstage_curation, devstage_curation_coarse, tissue_curation, tissue_curation_coarse from run_metadata where \"devstage_curation_coarse\" = :p0 and \"tissue_curation\" = :p1 order by rowid limit 101", "params": {"p0": "Adult", "p1": "Liver"}}, "facet_results": {"experiment.library_strategy": {"name": "experiment.library_strategy", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "RNA-Seq", "label": "RNA-Seq", "count": 978, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_strategy=RNA-Seq", "selected": false}, {"value": "OTHER", "label": "OTHER", "count": 21, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_strategy=OTHER", "selected": false}, {"value": "miRNA-Seq", "label": "miRNA-Seq", "count": 6, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_strategy=miRNA-Seq", "selected": false}], "truncated": false}, "experiment.library_source": {"name": "experiment.library_source", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "TRANSCRIPTOMIC", "label": "TRANSCRIPTOMIC", "count": 952, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_source=TRANSCRIPTOMIC", "selected": false}, {"value": "TRANSCRIPTOMIC SINGLE CELL", "label": "TRANSCRIPTOMIC SINGLE CELL", "count": 32, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_source=TRANSCRIPTOMIC+SINGLE+CELL", "selected": false}, {"value": "METATRANSCRIPTOMIC", "label": "METATRANSCRIPTOMIC", "count": 21, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_source=METATRANSCRIPTOMIC", "selected": false}], "truncated": false}, "experiment.library_selection": {"name": "experiment.library_selection", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "cDNA", "label": "cDNA", "count": 428, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=cDNA", "selected": false}, {"value": "PolyA", "label": "PolyA", "count": 156, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=PolyA", "selected": false}, {"value": "Oligo-dT", "label": "Oligo-dT", "count": 143, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=Oligo-dT", "selected": false}, {"value": "PCR", "label": "PCR", "count": 66, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=PCR", "selected": false}, {"value": "RANDOM", "label": "RANDOM", "count": 56, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=RANDOM", "selected": false}, {"value": "other", "label": "other", "count": 55, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=other", "selected": false}, {"value": "RT-PCR", "label": "RT-PCR", "count": 44, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=RT-PCR", "selected": false}, {"value": "RANDOM PCR", "label": "RANDOM PCR", "count": 41, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=RANDOM+PCR", "selected": false}, {"value": "size fractionation", "label": "size fractionation", "count": 10, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=size+fractionation", "selected": false}, {"value": "cDNA_oligo_dT", "label": "cDNA_oligo_dT", "count": 6, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_selection=cDNA_oligo_dT", "selected": false}], "truncated": false}, "experiment.library_layout": {"name": "experiment.library_layout", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "PAIRED", "label": "PAIRED", "count": 737, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_layout=PAIRED", "selected": false}, {"value": "SINGLE", "label": "SINGLE", "count": 268, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.library_layout=SINGLE", "selected": false}], "truncated": false}, "experiment.platform": {"name": "experiment.platform", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "ILLUMINA", "label": "ILLUMINA", "count": 951, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.platform=ILLUMINA", "selected": false}, {"value": "ABI_SOLID", "label": "ABI_SOLID", "count": 20, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.platform=ABI_SOLID", "selected": false}, {"value": "BGISEQ", "label": "BGISEQ", "count": 17, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.platform=BGISEQ", "selected": false}, {"value": "ION_TORRENT", "label": "ION_TORRENT", "count": 8, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.platform=ION_TORRENT", "selected": false}, {"value": "DNBSEQ", "label": "DNBSEQ", "count": 6, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.platform=DNBSEQ", "selected": false}, {"value": "PACBIO_SMRT", "label": "PACBIO_SMRT", "count": 3, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&experiment.platform=PACBIO_SMRT", "selected": false}], "truncated": false}, "devstage_curation_coarse": {"name": "devstage_curation_coarse", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "Adult", "label": "Adult", "count": 1005, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?tissue_curation=Liver", "selected": true}], "truncated": false}, "devstage_curation": {"name": "devstage_curation", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "Adult", "label": "Adult", "count": 980, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&devstage_curation=Adult", "selected": false}, {"value": "Undetermined", "label": "Undetermined", "count": 25, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&devstage_curation=Undetermined", "selected": false}], "truncated": false}, "tissue_curation_coarse": {"name": "tissue_curation_coarse", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "Liver and Biliary System", "label": "Liver and Biliary System", "count": 1005, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&tissue_curation_coarse=Liver+and+Biliary+System", "selected": false}], "truncated": false}, "tissue_curation": {"name": "tissue_curation", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "Liver", "label": "Liver", "count": 1005, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult", "selected": true}], "truncated": false}, "technology": {"name": "technology", "type": "column", "hideable": false, "toggle_url": "/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver", "results": [{"value": "unknown", "label": "unknown", "count": 887, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&technology=unknown", "selected": false}, {"value": "bulk", "label": "bulk", "count": 69, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&technology=bulk", "selected": false}, {"value": "dropseq", "label": "dropseq", "count": 28, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&technology=dropseq", "selected": false}, {"value": "10x", "label": "10x", "count": 21, "toggle_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&technology=10x", "selected": false}], "truncated": false}}, "suggested_facets": [], "next": "32528", "next_url": "http://metadata.rnaquarium.org/metadata/run_metadata.json?devstage_curation_coarse=Adult&tissue_curation=Liver&_next=32528", "private": false, "allow_execute_sql": true, "query_ms": 139.4962359991041}